Coexpression cluster:C69
From FANTOM5_SSTAR
Full id: C69_anaplastic_CD14_cord_hairy_mycosis_adult_NK
Phase1 CAGE Peaks
Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont
link to source dataset
data
No results for this coexpression
Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner
link to source dataset
data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0001525 | angiogenesis | 0.0299532388017022 |
GO:0048514 | blood vessel morphogenesis | 0.0299532388017022 |
GO:0048646 | anatomical structure formation | 0.0299532388017022 |
GO:0001568 | blood vessel development | 0.0299532388017022 |
GO:0003700 | transcription factor activity | 0.0299532388017022 |
GO:0001944 | vasculature development | 0.0299532388017022 |
GO:0045765 | regulation of angiogenesis | 0.0299532388017022 |
GO:0048513 | organ development | 0.0299532388017022 |
GO:0050576 | 3-keto-steroid reductase activity | 0.0299532388017022 |
GO:0043890 | N-acetylgalactosamine-6-sulfatase activity | 0.0299532388017022 |
GO:0022417 | protein maturation via protein folding | 0.0299532388017022 |
GO:0030852 | regulation of granulocyte differentiation | 0.0299532388017022 |
GO:0030854 | positive regulation of granulocyte differentiation | 0.0299532388017022 |
GO:0003806 | coagulation factor XIIa activity | 0.0299532388017022 |
GO:0005625 | soluble fraction | 0.0364471011885933 |
GO:0031404 | chloride ion binding | 0.0364471011885933 |
GO:0043168 | anion binding | 0.0364471011885933 |
GO:0003805 | coagulation factor XIa activity | 0.0364471011885933 |
GO:0015111 | iodide transmembrane transporter activity | 0.0364471011885933 |
GO:0005961 | glycine dehydrogenase complex (decarboxylating) | 0.0364471011885933 |
GO:0003943 | N-acetylgalactosamine-4-sulfatase activity | 0.0364471011885933 |
GO:0004375 | glycine dehydrogenase (decarboxylating) activity | 0.0364471011885933 |
GO:0016642 | oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor | 0.0364471011885933 |
GO:0005218 | intracellular ligand-gated calcium channel activity | 0.0483390129260326 |
GO:0042808 | neuronal Cdc2-like kinase binding | 0.0483390129260326 |
GO:0005219 | ryanodine-sensitive calcium-release channel activity | 0.0483390129260326 |
Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji
links to source dataset
cell_data
disease_data
Ontology term | p-value | n |
---|---|---|
T cell | 2.15e-09 | 25 |
pro-T cell | 2.15e-09 | 25 |
Ontology term | p-value | n |
---|---|---|
lymphoma | 3.81e-21 | 10 |
Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon
link to source data
Novel motifs
data
Jaspar motifs
data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0 |
MA0004.1 | 0.962286 |
MA0006.1 | 0.00560358 |
MA0007.1 | 0.155912 |
MA0009.1 | 0.107879 |
MA0014.1 | 0 |
MA0017.1 | 0.0193495 |
MA0019.1 | 1.06445 |
MA0024.1 | 0.0445766 |
MA0025.1 | 0.242411 |
MA0027.1 | 1.04498 |
MA0028.1 | 0.000146668 |
MA0029.1 | 0.840009 |
MA0030.1 | 0.5595 |
MA0031.1 | 0.131474 |
MA0038.1 | 0.0885885 |
MA0040.1 | 0.248059 |
MA0041.1 | 0.0740187 |
MA0042.1 | 0.327585 |
MA0043.1 | 0.906337 |
MA0046.1 | 0.862649 |
MA0048.1 | 6.18885e-10 |
MA0050.1 | 0.242563 |
MA0051.1 | 0.139734 |
MA0052.1 | 0.135212 |
MA0055.1 | 2.01495e-07 |
MA0056.1 | 0 |
MA0057.1 | 9.86502e-07 |
MA0058.1 | 0.654601 |
MA0059.1 | 0.928288 |
MA0060.1 | 5.98194e-05 |
MA0061.1 | 0.238759 |
MA0063.1 | 0 |
MA0066.1 | 0.776533 |
MA0067.1 | 0.521783 |
MA0068.1 | 0.0164718 |
MA0069.1 | 0.0967703 |
MA0070.1 | 0.193283 |
MA0071.1 | 1.55483 |
MA0072.1 | 1.42 |
MA0073.1 | 0 |
MA0074.1 | 0.00296922 |
MA0076.1 | 0.082594 |
MA0077.1 | 0.518038 |
MA0078.1 | 0.924786 |
MA0081.1 | 0.419064 |
MA0083.1 | 0.113824 |
MA0084.1 | 0.14994 |
MA0087.1 | 0.333777 |
MA0088.1 | 0.00663953 |
MA0089.1 | 0 |
MA0090.1 | 0.29734 |
MA0091.1 | 0.514763 |
MA0092.1 | 1.85294 |
MA0093.1 | 1.0397 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.02947 |
MA0101.1 | 0.11906 |
MA0103.1 | 0.117844 |
MA0105.1 | 0.000991798 |
MA0106.1 | 0.231453 |
MA0107.1 | 0.0343119 |
MA0108.2 | 0.127942 |
MA0109.1 | 0 |
MA0111.1 | 0.268252 |
MA0113.1 | 0.271474 |
MA0114.1 | 0.321178 |
MA0115.1 | 0.174506 |
MA0116.1 | 0.00150873 |
MA0117.1 | 0.0101983 |
MA0119.1 | 0.254777 |
MA0122.1 | 0.833712 |
MA0124.1 | 1.81398 |
MA0125.1 | 0.0878098 |
MA0130.1 | 0 |
MA0131.1 | 0.00168401 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.02786 |
MA0136.1 | 0.159878 |
MA0139.1 | 2.10362e-06 |
MA0140.1 | 0.00417101 |
MA0141.1 | 2.84366 |
MA0142.1 | 0.0449718 |
MA0143.1 | 0.0556221 |
MA0144.1 | 4.64019 |
MA0145.1 | 8.33532e-05 |
MA0146.1 | 6.47443e-10 |
MA0147.1 | 0.492541 |
MA0148.1 | 1.17867 |
MA0149.1 | 0.810824 |
MA0062.2 | 6.05555e-05 |
MA0035.2 | 0.0108283 |
MA0039.2 | 9.64327e-17 |
MA0138.2 | 0.01793 |
MA0002.2 | 4.45089 |
MA0137.2 | 5.54195 |
MA0104.2 | 0.0977134 |
MA0047.2 | 0.304585 |
MA0112.2 | 0.000286053 |
MA0065.2 | 0.17095 |
MA0150.1 | 4.39482 |
MA0151.1 | 0 |
MA0152.1 | 0.440521 |
MA0153.1 | 0.201512 |
MA0154.1 | 0.01842 |
MA0155.1 | 2.3897e-05 |
MA0156.1 | 0.302034 |
MA0157.1 | 0.237148 |
MA0158.1 | 0 |
MA0159.1 | 0.0439867 |
MA0160.1 | 0.911058 |
MA0161.1 | 0 |
MA0162.1 | 0 |
MA0163.1 | 3.62369e-08 |
MA0164.1 | 0.0651096 |
MA0080.2 | 0.430018 |
MA0018.2 | 0.0452359 |
MA0099.2 | 5.87635 |
MA0079.2 | 0 |
MA0102.2 | 2.21983 |
MA0258.1 | 1.05993 |
MA0259.1 | 0.0797644 |
MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner
link to source dataset
data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
TF | #promoters | Enrichment | p-value | q-value |
---|---|---|---|---|
BATF#10538 | 19 | 1.80077133873062 | 0.0103911178957476 | 0.0385807516056022 |
STAT3#6774 | 45 | 1.84192966876242 | 4.75053594801859e-05 | 0.00082621352851809 |
Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA
link to data source
data