MCL coexpression mm9:1358
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr14:26588519..26588569,- | p1@Zcchc24 |
| Mm9::chr15:78004386..78004418,- | p2@Ift27 |
| Mm9::chr5:116102983..116103001,- | p1@Ccdc64 |
| Mm9::chr5:137463227..137463253,+ | p3@Plod3 |
| Mm9::chr5:34000486..34000536,- | p2@Tmem129 |
| Mm9::chr7:150238681..150238702,+ | p1@Cd81 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0008475 | procollagen-lysine 5-dioxygenase activity | 0.0207066553792883 |
| GO:0030307 | positive regulation of cell growth | 0.0207066553792883 |
| GO:0045793 | positive regulation of cell size | 0.0230048737377879 |
| GO:0030890 | positive regulation of B cell proliferation | 0.037222988647217 |
| GO:0031418 | L-ascorbic acid binding | 0.037222988647217 |
| GO:0030888 | regulation of B cell proliferation | 0.037222988647217 |
| GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | 0.037222988647217 |
| GO:0050871 | positive regulation of B cell activation | 0.037222988647217 |
| GO:0045927 | positive regulation of growth | 0.037222988647217 |
| GO:0042100 | B cell proliferation | 0.037222988647217 |
| GO:0032946 | positive regulation of mononuclear cell proliferation | 0.0392164037242194 |
| GO:0050671 | positive regulation of lymphocyte proliferation | 0.0392164037242194 |
| GO:0050864 | regulation of B cell activation | 0.0392164037242194 |
| GO:0032944 | regulation of mononuclear cell proliferation | 0.0441788138872621 |
| GO:0050670 | regulation of lymphocyte proliferation | 0.0441788138872621 |
| GO:0051213 | dioxygenase activity | 0.0441788138872621 |
| GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | 0.0441788138872621 |
| GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | 0.0441788138872621 |
| GO:0051251 | positive regulation of lymphocyte activation | 0.0441788138872621 |
| GO:0032943 | mononuclear cell proliferation | 0.0472716327546309 |
| GO:0046651 | lymphocyte proliferation | 0.0472716327546309 |
| GO:0001558 | regulation of cell growth | 0.0472716327546309 |
| GO:0051249 | regulation of lymphocyte activation | 0.0472716327546309 |
| GO:0042113 | B cell activation | 0.0472716327546309 |
| GO:0050865 | regulation of cell activation | 0.0472716327546309 |
| GO:0016049 | cell growth | 0.0496599180348516 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| non-terminally differentiated cell | 3.25e-07 | 49 |
| oligodendrocyte precursor cell | 6.68e-07 | 8 |
| Ontology term | p-value | n |
|---|---|---|
| tube | 4.86e-15 | 114 |
| anatomical conduit | 1.97e-14 | 122 |
| central nervous system | 9.91e-09 | 73 |
| nervous system | 1.49e-08 | 75 |
| structure with developmental contribution from neural crest | 3.36e-08 | 92 |
| cardiovascular system | 3.32e-07 | 23 |
| circulatory system | 3.32e-07 | 23 |
| epithelial tube | 3.93e-07 | 47 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 3.21844 |
| MA0004.1 | 0.536396 |
| MA0006.1 | 0.359699 |
| MA0007.1 | 1.29371 |
| MA0009.1 | 0.987341 |
| MA0014.1 | 0.304529 |
| MA0017.1 | 0.387481 |
| MA0019.1 | 0.800946 |
| MA0024.1 | 0.942716 |
| MA0025.1 | 1.22395 |
| MA0027.1 | 2.64231 |
| MA0028.1 | 0.370592 |
| MA0029.1 | 0.920529 |
| MA0030.1 | 0.927235 |
| MA0031.1 | 0.890871 |
| MA0038.1 | 0.686534 |
| MA0040.1 | 1.00009 |
| MA0041.1 | 0.457338 |
| MA0042.1 | 0.443591 |
| MA0043.1 | 1.08567 |
| MA0046.1 | 1.02391 |
| MA0048.1 | 0.161427 |
| MA0050.1 | 0.57678 |
| MA0051.1 | 0.695779 |
| MA0052.1 | 1.00829 |
| MA0055.1 | 0.0585191 |
| MA0056.1 | 0 |
| MA0057.1 | 0.457693 |
| MA0058.1 | 0.436487 |
| MA0059.1 | 0.449345 |
| MA0060.1 | 1.38604 |
| MA0061.1 | 0.307097 |
| MA0063.1 | 0 |
| MA0066.1 | 0.675169 |
| MA0067.1 | 1.33603 |
| MA0068.1 | 0.467569 |
| MA0069.1 | 1.00864 |
| MA0070.1 | 0.998765 |
| MA0071.1 | 0.575909 |
| MA0072.1 | 0.990133 |
| MA0073.1 | 0.0198269 |
| MA0074.1 | 0.638014 |
| MA0076.1 | 0.407465 |
| MA0077.1 | 0.968053 |
| MA0078.1 | 0.729877 |
| MA0081.1 | 0.473489 |
| MA0083.1 | 1.08487 |
| MA0084.1 | 1.66561 |
| MA0087.1 | 1.04109 |
| MA0088.1 | 2.36749 |
| MA0089.1 | 0 |
| MA0090.1 | 0.500693 |
| MA0091.1 | 0.55008 |
| MA0092.1 | 0.501022 |
| MA0093.1 | 0.379257 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.626021 |
| MA0101.1 | 0.458688 |
| MA0103.1 | 0.398766 |
| MA0105.1 | 0.199622 |
| MA0106.1 | 0.737893 |
| MA0107.1 | 0.392331 |
| MA0108.2 | 0.824407 |
| MA0109.1 | 0 |
| MA0111.1 | 0.515457 |
| MA0113.1 | 0.708789 |
| MA0114.1 | 0.304661 |
| MA0115.1 | 1.08851 |
| MA0116.1 | 0.944657 |
| MA0117.1 | 1.05576 |
| MA0119.1 | 0.459301 |
| MA0122.1 | 1.07591 |
| MA0124.1 | 1.28237 |
| MA0125.1 | 1.20757 |
| MA0130.1 | 0 |
| MA0131.1 | 0.796279 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.1226 |
| MA0136.1 | 0.658622 |
| MA0139.1 | 0.243463 |
| MA0140.1 | 0.625902 |
| MA0141.1 | 1.07584 |
| MA0142.1 | 0.876028 |
| MA0143.1 | 0.725672 |
| MA0144.1 | 0.829535 |
| MA0145.1 | 0.119202 |
| MA0146.1 | 2.42438 |
| MA0147.1 | 0.320675 |
| MA0148.1 | 0.553294 |
| MA0149.1 | 0.464445 |
| MA0062.2 | 0.204999 |
| MA0035.2 | 0.630778 |
| MA0039.2 | 2.61252 |
| MA0138.2 | 0.788113 |
| MA0002.2 | 0.689262 |
| MA0137.2 | 0.416331 |
| MA0104.2 | 0.261255 |
| MA0047.2 | 0.685741 |
| MA0112.2 | 0.76177 |
| MA0065.2 | 0.763394 |
| MA0150.1 | 0.520653 |
| MA0151.1 | 0 |
| MA0152.1 | 0.685852 |
| MA0153.1 | 1.13945 |
| MA0154.1 | 0.480757 |
| MA0155.1 | 1.33283 |
| MA0156.1 | 0.406559 |
| MA0157.1 | 0.843181 |
| MA0158.1 | 0 |
| MA0159.1 | 1.58527 |
| MA0160.1 | 1.36931 |
| MA0161.1 | 0 |
| MA0162.1 | 2.04167 |
| MA0163.1 | 1.4645 |
| MA0164.1 | 0.658997 |
| MA0080.2 | 0.393257 |
| MA0018.2 | 0.669032 |
| MA0099.2 | 0.781628 |
| MA0079.2 | 0.911432 |
| MA0102.2 | 1.7182 |
| MA0258.1 | 0.290587 |
| MA0259.1 | 0.309517 |
| MA0442.1 | 0 |
