MCL coexpression mm9:263
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont
link to source dataset
data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0043121 | neurotrophin binding | 0.0220018627075001 |
GO:0017049 | GTP-Rho binding | 0.0220018627075001 |
GO:0001829 | trophectodermal cell differentiation | 0.0220018627075001 |
GO:0048199 | vesicle targeting, to, from or within Golgi | 0.0220018627075001 |
GO:0048406 | nerve growth factor binding | 0.0220018627075001 |
GO:0009653 | anatomical structure morphogenesis | 0.0274970545431882 |
GO:0042488 | positive regulation of odontogenesis of dentine-containing teeth | 0.0274970545431882 |
GO:0042482 | positive regulation of odontogenesis | 0.0274970545431882 |
GO:0042481 | regulation of odontogenesis | 0.0305347110597331 |
GO:0005095 | GTPase inhibitor activity | 0.0305347110597331 |
GO:0042589 | zymogen granule membrane | 0.0305347110597331 |
GO:0007399 | nervous system development | 0.0305347110597331 |
GO:0048667 | neuron morphogenesis during differentiation | 0.0305347110597331 |
GO:0048812 | neurite morphogenesis | 0.0305347110597331 |
GO:0005035 | death receptor activity | 0.0305347110597331 |
GO:0001825 | blastocyst formation | 0.0305347110597331 |
GO:0042588 | zymogen granule | 0.0305347110597331 |
GO:0042487 | regulation of odontogenesis of dentine-containing teeth | 0.0305347110597331 |
GO:0006903 | vesicle targeting | 0.0328181267948919 |
GO:0016048 | detection of temperature stimulus | 0.0328181267948919 |
GO:0000904 | cellular morphogenesis during differentiation | 0.0328181267948919 |
GO:0031175 | neurite development | 0.0328181267948919 |
GO:0005801 | cis-Golgi network | 0.0328181267948919 |
GO:0032502 | developmental process | 0.0328181267948919 |
GO:0048731 | system development | 0.0328181267948919 |
GO:0030667 | secretory granule membrane | 0.0328181267948919 |
GO:0048869 | cellular developmental process | 0.0328181267948919 |
GO:0030154 | cell differentiation | 0.0328181267948919 |
GO:0048666 | neuron development | 0.0328181267948919 |
GO:0021675 | nerve development | 0.0355230660621697 |
GO:0043588 | skin development | 0.0355230660621697 |
GO:0035257 | nuclear hormone receptor binding | 0.0355230660621697 |
GO:0051650 | establishment of vesicle localization | 0.0355230660621697 |
GO:0001892 | embryonic placenta development | 0.0355230660621697 |
GO:0051427 | hormone receptor binding | 0.0356708540809494 |
GO:0051648 | vesicle localization | 0.0356708540809494 |
GO:0032990 | cell part morphogenesis | 0.0356708540809494 |
GO:0048858 | cell projection morphogenesis | 0.0356708540809494 |
GO:0030030 | cell projection organization and biogenesis | 0.0356708540809494 |
GO:0051017 | actin filament bundle formation | 0.0356708540809494 |
GO:0048856 | anatomical structure development | 0.0358024264734813 |
GO:0030182 | neuron differentiation | 0.0361493430947323 |
GO:0017048 | Rho GTPase binding | 0.042373404854525 |
GO:0030041 | actin filament polymerization | 0.042373404854525 |
GO:0048699 | generation of neurons | 0.0432869659028584 |
GO:0007275 | multicellular organismal development | 0.0474875106611709 |
GO:0022008 | neurogenesis | 0.0474875106611709 |
GO:0051656 | establishment of organelle localization | 0.0479448740767939 |
Relative expression of the co-expression cluster over median
Analyst:
Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji
links to source dataset
cell_data
uberon_data
Ontology term | p-value | n |
---|---|---|
autonomic neuron | 2.00e-13 | 9 |
ectodermal cell | 2.50e-10 | 44 |
neurectodermal cell | 2.50e-10 | 44 |
neural cell | 1.76e-09 | 43 |
neuron | 2.47e-08 | 33 |
neuronal stem cell | 2.47e-08 | 33 |
neuroblast | 2.47e-08 | 33 |
electrically signaling cell | 2.47e-08 | 33 |
non-terminally differentiated cell | 1.48e-07 | 49 |
Ontology term | p-value | n |
---|---|---|
peripheral nervous system | 3.09e-16 | 11 |
autonomic nervous system | 2.00e-13 | 9 |
spinal cord | 6.37e-08 | 6 |
dorsal region element | 6.37e-08 | 6 |
dorsum | 6.37e-08 | 6 |
regional part of spinal cord | 2.77e-07 | 5 |
gray matter of spinal cord | 2.77e-07 | 5 |
ectoderm-derived structure | 5.98e-07 | 95 |
ectoderm | 5.98e-07 | 95 |
presumptive ectoderm | 5.98e-07 | 95 |
TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon
link to source data
Novel motifs
data
Jaspar motifs
data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.328739 |
MA0004.1 | 0.075713 |
MA0006.1 | 0.228715 |
MA0007.1 | 0.0693451 |
MA0009.1 | 0.356735 |
MA0014.1 | 0.348616 |
MA0017.1 | 0.272987 |
MA0019.1 | 0.221321 |
MA0024.1 | 0.322453 |
MA0025.1 | 0.553002 |
MA0027.1 | 1.91746 |
MA0028.1 | 0.0230932 |
MA0029.1 | 0.305809 |
MA0030.1 | 0.31081 |
MA0031.1 | 0.284004 |
MA0038.1 | 0.89669 |
MA0040.1 | 0.366712 |
MA0041.1 | 0.0464556 |
MA0042.1 | 0.371303 |
MA0043.1 | 0.435645 |
MA0046.1 | 0.385571 |
MA0048.1 | 0.364526 |
MA0050.1 | 0.311127 |
MA0051.1 | 0.155655 |
MA0052.1 | 1.73218 |
MA0055.1 | 0.0656494 |
MA0056.1 | 0 |
MA0057.1 | 0.664918 |
MA0058.1 | 0.156036 |
MA0059.1 | 0.381997 |
MA0060.1 | 0.116099 |
MA0061.1 | 0.310047 |
MA0063.1 | 0 |
MA0066.1 | 0.143893 |
MA0067.1 | 0.652366 |
MA0068.1 | 1.19329 |
MA0069.1 | 0.975461 |
MA0070.1 | 0.365675 |
MA0071.1 | 0.310039 |
MA0072.1 | 0.358914 |
MA0073.1 | 4.23588 |
MA0074.1 | 0.391044 |
MA0076.1 | 0.0318933 |
MA0077.1 | 0.905433 |
MA0078.1 | 0.175945 |
MA0081.1 | 0.192641 |
MA0083.1 | 0.434982 |
MA0084.1 | 0.958921 |
MA0087.1 | 0.399335 |
MA0088.1 | 0.559807 |
MA0089.1 | 0 |
MA0090.1 | 0.481928 |
MA0091.1 | 0.584863 |
MA0092.1 | 1.76058 |
MA0093.1 | 0.106412 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.117472 |
MA0101.1 | 0.177595 |
MA0103.1 | 0.122326 |
MA0105.1 | 0.355784 |
MA0106.1 | 1.02229 |
MA0107.1 | 0.0280799 |
MA0108.2 | 0.237143 |
MA0109.1 | 0 |
MA0111.1 | 0.238061 |
MA0113.1 | 0.490789 |
MA0114.1 | 0.787303 |
MA0115.1 | 0.437985 |
MA0116.1 | 1.43356 |
MA0117.1 | 0.411186 |
MA0119.1 | 0.400754 |
MA0122.1 | 0.427622 |
MA0124.1 | 0.604388 |
MA0125.1 | 0.538769 |
MA0130.1 | 0 |
MA0131.1 | 0.623192 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.466327 |
MA0136.1 | 0.419326 |
MA0139.1 | 0.00479353 |
MA0140.1 | 0.117411 |
MA0141.1 | 1.33852 |
MA0142.1 | 0.27329 |
MA0143.1 | 0.515613 |
MA0144.1 | 0.311788 |
MA0145.1 | 0.0245594 |
MA0146.1 | 0.0233321 |
MA0147.1 | 0.341028 |
MA0148.1 | 0.996586 |
MA0149.1 | 6.1348 |
MA0062.2 | 0.117118 |
MA0035.2 | 0.119926 |
MA0039.2 | 0.275067 |
MA0138.2 | 0.61046 |
MA0002.2 | 0.336369 |
MA0137.2 | 0.585976 |
MA0104.2 | 0.213989 |
MA0047.2 | 0.457516 |
MA0112.2 | 0.0575877 |
MA0065.2 | 0.197264 |
MA0150.1 | 0.0692983 |
MA0151.1 | 0 |
MA0152.1 | 0.457674 |
MA0153.1 | 0.480495 |
MA0154.1 | 0.221011 |
MA0155.1 | 0.0344296 |
MA0156.1 | 0.128979 |
MA0157.1 | 0.250083 |
MA0158.1 | 0 |
MA0159.1 | 0.365833 |
MA0160.1 | 0.0842824 |
MA0161.1 | 0 |
MA0162.1 | 0.609369 |
MA0163.1 | 0.533899 |
MA0164.1 | 0.419846 |
MA0080.2 | 0.523079 |
MA0018.2 | 0.433858 |
MA0099.2 | 1.77332 |
MA0079.2 | 0.411928 |
MA0102.2 | 1.0092 |
MA0258.1 | 0.273872 |
MA0259.1 | 0.533842 |
MA0442.1 | 0 |