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MCL coexpression mm9:394

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:79579860..79579871,-p@chr10:79579860..79579871
-
Mm9::chr11:115628094..115628110,+p5@2310067B10Rik
Mm9::chr11:6192037..6192053,+p11@Ogdh
Mm9::chr11:69760911..69760934,-p@chr11:69760911..69760934
-
Mm9::chr11:95686473..95686493,+p@chr11:95686473..95686493
+
Mm9::chr12:37833337..37833344,-p@chr12:37833337..37833344
-
Mm9::chr15:101091097..101091115,+p@chr15:101091097..101091115
+
Mm9::chr15:89256249..89256282,-p1@Cpt1b
Mm9::chr16:43364103..43364130,+p30@Zbtb20
Mm9::chr19:5848495..5848522,+p1@ENSMUST00000135347
p1@uc012bhf.1
Mm9::chr1:182123606..182123623,-p2@Adck3
Mm9::chr2:26465282..26465293,+p@chr2:26465282..26465293
+
Mm9::chr5:114596684..114596724,+p1@Acacb
Mm9::chr6:5446296..5446316,-p1@Pdk4
Mm9::chr6:86466170..86466203,-p2@uc009csb.1
Mm9::chr7:137696485..137696499,+p@chr7:137696485..137696499
+
Mm9::chr7:146037793..146037814,-p3@Mapk1ip1
Mm9::chr7:148086300..148086318,-p1@Cox8b
Mm9::chr7:53152416..53152459,+p1@Tmem143


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0050164oxoglutarate dehydrogenase (NADP+) activity0.0203257535509281
GO:0005739mitochondrion0.0203257535509281
GO:0006006glucose metabolic process0.0203257535509281
GO:0009343biotin carboxylase complex0.0203257535509281
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity0.0203257535509281
GO:0015909long-chain fatty acid transport0.0203257535509281
GO:0009317acetyl-CoA carboxylase complex0.0203257535509281
GO:0004075biotin carboxylase activity0.0203257535509281
GO:0006086acetyl-CoA biosynthetic process from pyruvate0.0203257535509281
GO:0003989acetyl-CoA carboxylase activity0.0203257535509281
GO:0030976thiamin pyrophosphate binding0.0203257535509281
GO:0019318hexose metabolic process0.0203257535509281
GO:0005996monosaccharide metabolic process0.0203257535509281
GO:0016416O-palmitoyltransferase activity0.0203257535509281
GO:0004095carnitine O-palmitoyltransferase activity0.0203257535509281
GO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activity0.0203257535509281
GO:0015908fatty acid transport0.0212001878857225
GO:0009401phosphoenolpyruvate-dependent sugar phosphotransferase system0.0212001878857225
GO:0018106peptidyl-histidine phosphorylation0.0212001878857225
GO:0006085acetyl-CoA biosynthetic process0.0212001878857225
GO:0016421CoA carboxylase activity0.0212001878857225
GO:0018202peptidyl-histidine modification0.0212001878857225
GO:0016406carnitine O-acyltransferase activity0.0212001878857225
GO:0016624oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor0.0227498824205088
GO:0016885ligase activity, forming carbon-carbon bonds0.0227498824205088
GO:0004712protein serine/threonine/tyrosine kinase activity0.0249943931706218
GO:0032787monocarboxylic acid metabolic process0.0282512687771836
GO:0004673protein histidine kinase activity0.0289986381866018
GO:0031966mitochondrial membrane0.0341836849493751
GO:0044262cellular carbohydrate metabolic process0.0341836849493751
GO:0006066alcohol metabolic process0.0346510387827957
GO:0016775phosphotransferase activity, nitrogenous group as acceptor0.0354922136400253
GO:0005740mitochondrial envelope0.0357826276418746
GO:0016409palmitoyltransferase activity0.0357826276418746
GO:0044444cytoplasmic part0.0405003810754452
GO:0005741mitochondrial outer membrane0.0405003810754452
GO:0044429mitochondrial part0.0405003810754452
GO:0004129cytochrome-c oxidase activity0.0405003810754452
GO:0006090pyruvate metabolic process0.0405003810754452
GO:0016676oxidoreductase activity, acting on heme group of donors, oxygen as acceptor0.0405003810754452
GO:0015002heme-copper terminal oxidase activity0.0405003810754452
GO:0016675oxidoreductase activity, acting on heme group of donors0.0405003810754452
GO:0031968organelle outer membrane0.0414331748193682
GO:0005975carbohydrate metabolic process0.0445371017946409
GO:0031975envelope0.0494077548759043
GO:0031967organelle envelope0.0494077548759043
GO:0016620oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor0.0498917110559975



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
primary circulatory organ2.32e-0918
heart2.32e-0918
primitive heart tube2.32e-0918
primary heart field2.32e-0918
anterior lateral plate mesoderm2.32e-0918
heart tube2.32e-0918
heart primordium2.32e-0918
cardiac mesoderm2.32e-0918
cardiogenic plate2.32e-0918
heart rudiment2.32e-0918
cardiovascular system1.99e-0823
circulatory system1.99e-0823


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0710448
MA0004.10.527785
MA0006.10.0769247
MA0007.10.970795
MA0009.10.535932
MA0014.10.0353374
MA0017.10.0906268
MA0019.10.376509
MA0024.10.496718
MA0025.10.751694
MA0027.12.14278
MA0028.10.0821841
MA0029.10.477444
MA0030.10.483253
MA0031.10.451927
MA0038.10.285714
MA0040.11.34987
MA0041.10.805215
MA0042.10.384176
MA0043.10.624178
MA0046.10.568473
MA0048.10.145518
MA0050.10.205672
MA0051.10.2928
MA0052.11.36531
MA0055.10.473971
MA0056.10
MA0057.10.262449
MA0058.10.373672
MA0059.10.124358
MA0060.10.161631
MA0061.10.438647
MA0063.10
MA0066.10.277072
MA0067.10.857286
MA0068.10.273642
MA0069.10.554839
MA0070.10.54606
MA0071.11.1183
MA0072.10.538403
MA0073.10.0405835
MA0074.10.249359
MA0076.10.331592
MA0077.10.518913
MA0078.10.319336
MA0081.10.138626
MA0083.10.623446
MA0084.11.1752
MA0087.10.583879
MA0088.10.294412
MA0089.10
MA0090.10.471234
MA0091.10.187483
MA0092.10.155586
MA0093.10.609251
MA0095.10
MA0098.10
MA0100.10.2406
MA0101.10.40675
MA0103.10.319254
MA0105.10.410191
MA0106.10.325663
MA0107.10.310214
MA0108.21.02466
MA0109.10
MA0111.10.956743
MA0113.10.818211
MA0114.11.16017
MA0115.10.626759
MA0116.10.561344
MA0117.10.597086
MA0119.10.407675
MA0122.10.615314
MA0124.10.80652
MA0125.10.736412
MA0130.10
MA0131.12.60364
MA0132.10
MA0133.10
MA0135.10.657882
MA0136.10.264624
MA0139.10.872959
MA0140.10.675435
MA0141.12.327
MA0142.10.439269
MA0143.10.31603
MA0144.10.19926
MA0145.10.522455
MA0146.10.427848
MA0147.10.0593437
MA0148.10.189643
MA0149.10.133214
MA0062.20.0201154
MA0035.20.68369
MA0039.20.175076
MA0138.20.366012
MA0002.20.560759
MA0137.20.105829
MA0104.20.145321
MA0047.20.285109
MA0112.22.16314
MA0065.20.524507
MA0150.10.168102
MA0151.10
MA0152.10.285194
MA0153.10.67335
MA0154.10.755185
MA0155.10.215697
MA0156.10.100572
MA0157.10.411541
MA0158.10
MA0159.10.494347
MA0160.12.38263
MA0161.10
MA0162.10.00257384
MA0163.10.319278
MA0164.10.264905
MA0080.20.0935932
MA0018.20.272436
MA0099.20.947425
MA0079.20.0408007
MA0102.21.22663
MA0258.12.61782
MA0259.10.201267
MA0442.10
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