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MCL coexpression mm9:600

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Phase1 CAGE Peaks

  Short description
Mm9::chr11:118165162..118165220,- p@chr11:118165162..118165220
-
Mm9::chr11:5763981..5764006,+ +
p@chr11:5763981..5764006
Mm9::chr11:5770554..5770565,+ p@chr11:5770554..5770565
+
Mm9::chr11:5771774..5771785,+ p@chr11:5771774..5771785
+
Mm9::chr17:29227914..29227965,+ p2@Cdkn1a
Mm9::chr1:137662795..137662802,+ p3@Phlda3
Mm9::chr1:137662818..137662834,+ p2@Phlda3
Mm9::chr4:88920480..88920487,- p@chr4:88920480..88920487
-
Mm9::chr4:88928017..88928055,- p2@Cdkn2a
Mm9::chr4:88928056..88928065,- p4@Cdkn2a
Mm9::chr7:74764902..74764914,- p@chr7:74764902..74764914
-
Mm9::chr9:58095257..58095272,- -
p@chr9:58095257..58095272


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0045736negative regulation of cyclin-dependent protein kinase activity6.23135703143626e-06
GO:0004861cyclin-dependent protein kinase inhibitor activity1.45398330733513e-05
GO:0000079regulation of cyclin-dependent protein kinase activity1.90402575960552e-05
GO:0004860protein kinase inhibitor activity3.9984540951716e-05
GO:0030888regulation of B cell proliferation3.9984540951716e-05
GO:0019210kinase inhibitor activity3.9984540951716e-05
GO:0042100B cell proliferation5.20763409055744e-05
GO:0006469negative regulation of protein kinase activity6.63733938348437e-05
GO:0033673negative regulation of kinase activity6.63733938348437e-05
GO:0050864regulation of B cell activation6.63733938348437e-05
GO:0051348negative regulation of transferase activity6.63733938348437e-05
GO:0007050cell cycle arrest8.56811591822485e-05
GO:0043086negative regulation of catalytic activity8.63602173202896e-05
GO:0050670regulation of lymphocyte proliferation9.5408999881324e-05
GO:0032944regulation of mononuclear cell proliferation9.5408999881324e-05
GO:0019887protein kinase regulator activity0.000126769169608281
GO:0032943mononuclear cell proliferation0.000147639432823766
GO:0019207kinase regulator activity0.000147639432823766
GO:0046651lymphocyte proliferation0.000147639432823766
GO:0051249regulation of lymphocyte activation0.000172542499620451
GO:0042113B cell activation0.000172542499620451
GO:0050865regulation of cell activation0.000172542499620451
GO:0045786negative regulation of progression through cell cycle0.000298715677694475
GO:0008285negative regulation of cell proliferation0.000298715677694475
GO:0045859regulation of protein kinase activity0.00033238058405681
GO:0043549regulation of kinase activity0.000345360980088448
GO:0051338regulation of transferase activity0.000347917434255191
GO:0000074regulation of progression through cell cycle0.000584300995929853
GO:0046649lymphocyte activation0.00059236837780091
GO:0043071positive regulation of non-apoptotic programmed cell death0.00059236837780091
GO:0016244non-apoptotic programmed cell death0.00059236837780091
GO:0043070regulation of non-apoptotic programmed cell death0.00059236837780091
GO:0045321leukocyte activation0.000644975998621454
GO:0004857enzyme inhibitor activity0.000644975998621454
GO:0001775cell activation0.000721353759210549
GO:0050790regulation of catalytic activity0.000997645726835604
GO:0033087negative regulation of immature T cell proliferation0.000997645726835604
GO:0033088negative regulation of immature T cell proliferation in the thymus0.000997645726835604
GO:0051239regulation of multicellular organismal process0.0010253245289803
GO:0065009regulation of a molecular function0.001243545187586
GO:0042127regulation of cell proliferation0.00126871442388828
GO:0030332cyclin binding0.00135391068072313
GO:0051726regulation of cell cycle0.00147511678563941
GO:0033080immature T cell proliferation in the thymus0.001613125978755
GO:0033079immature T cell proliferation0.001613125978755
GO:0033083regulation of immature T cell proliferation0.001613125978755
GO:0033084regulation of immature T cell proliferation in the thymus0.001613125978755
GO:0008283cell proliferation0.00230410917234263
GO:0048103somatic stem cell division0.00232079898255502
GO:0000307cyclin-dependent protein kinase holoenzyme complex0.00265337413755587
GO:0030889negative regulation of B cell proliferation0.00297288676570365
GO:0022402cell cycle process0.00303730721766891
GO:0017145stem cell division0.00321820197480138
GO:0006915apoptosis0.00347919357513534
GO:0012501programmed cell death0.00353046029921064
GO:0050869negative regulation of B cell activation0.00363859322660616
GO:0008219cell death0.00363859322660616
GO:0016265death0.00363859322660616
GO:0007569cell aging0.00410573729206283
GO:0030890positive regulation of B cell proliferation0.00410573729206283
GO:0007049cell cycle0.00412965310414495
GO:0002376immune system process0.00431174729559889
GO:0048523negative regulation of cellular process0.00550853610086116
GO:0050672negative regulation of lymphocyte proliferation0.00553819046196241
GO:0032945negative regulation of mononuclear cell proliferation0.00553819046196241
GO:0016301kinase activity0.00562450782962479
GO:0048519negative regulation of biological process0.00598149821554142
GO:0009411response to UV0.00676547334841651
GO:0033077T cell differentiation in the thymus0.00676547334841651
GO:0051250negative regulation of lymphocyte activation0.00676547334841651
GO:0016772transferase activity, transferring phosphorus-containing groups0.00684045775682157
GO:0050871positive regulation of B cell activation0.00684045775682157
GO:0007568aging0.00726533549337855
GO:0048468cell development0.00859156771462019
GO:0032946positive regulation of mononuclear cell proliferation0.00897044840445193
GO:0050671positive regulation of lymphocyte proliferation0.00897044840445193
GO:0042129regulation of T cell proliferation0.0103279077926027
GO:0016072rRNA metabolic process0.0126990586550902
GO:0006364rRNA processing0.0126990586550902
GO:0042098T cell proliferation0.013012826050804
GO:0051251positive regulation of lymphocyte activation0.014078079385034
GO:0030217T cell differentiation0.014078079385034
GO:0050863regulation of T cell activation0.0143636908787096
GO:0009416response to light stimulus0.0164409904305137
GO:0048869cellular developmental process0.0169711008751167
GO:0030154cell differentiation0.0169711008751167
GO:0016740transferase activity0.0177298342497547
GO:0030098lymphocyte differentiation0.0197578127502482
GO:0009314response to radiation0.0197578127502482
GO:0008544epidermis development0.0201668869473389
GO:0007398ectoderm development0.0209812073796822
GO:0005730nucleolus0.0219823875503924
GO:0042110T cell activation0.0239743421323824
GO:0042254ribosome biogenesis and assembly0.0249212517907133
GO:0002521leukocyte differentiation0.0252534270819102
GO:0043066negative regulation of apoptosis0.0293016798776038
GO:0043069negative regulation of programmed cell death0.0293872403622387
GO:0043068positive regulation of programmed cell death0.031771972700846
GO:0009628response to abiotic stimulus0.0320202372355373
GO:0008284positive regulation of cell proliferation0.0332022488739404
GO:0022613ribonucleoprotein complex biogenesis and assembly0.0352890386214833
GO:0030097hemopoiesis0.038435743270726
GO:0032502developmental process0.0396246347091916
GO:0006974response to DNA damage stimulus0.0415787003990648
GO:0048534hemopoietic or lymphoid organ development0.0415787003990648
GO:0051301cell division0.0415787003990648
GO:0002520immune system development0.0435798320167287
GO:0009719response to endogenous stimulus0.0435798320167287
GO:0050794regulation of cellular process0.046956514775283
GO:0009888tissue development0.048051995656815



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Uber Anatomy
Ontology termp-valuen
peripheral nervous system2.56e-1211
autonomic nervous system9.73e-119


TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.829197
MA0004.10.303605
MA0006.10.16569
MA0007.10.790701
MA0009.10.709264
MA0014.11.34901
MA0017.10.546298
MA0019.10.535691
MA0024.10.667197
MA0025.10.936082
MA0027.12.34178
MA0028.10.173587
MA0029.11.55834
MA0030.10.65267
MA0031.10.618697
MA0038.10.432665
MA0040.10.721328
MA0041.10.239557
MA0042.10.228771
MA0043.10.802848
MA0046.10.743934
MA0048.10.168666
MA0050.10.337476
MA0051.10.440863
MA0052.10.729105
MA0055.10.10681
MA0056.10
MA0057.10.630087
MA0058.10.223242
MA0059.10.233271
MA0060.10.351437
MA0061.10.40468
MA0063.10
MA0066.11.08293
MA0067.11.04514
MA0068.10.0405002
MA0069.10.729433
MA0070.10.720077
MA0071.10.336739
MA0072.10.711905
MA0073.11.47506
MA0074.10.390075
MA0076.10.200996
MA0077.10.691048
MA0078.10.471303
MA0081.10.702944
MA0083.10.802078
MA0084.11.3693
MA0087.10.760279
MA0088.11.08862
MA0089.10
MA0090.11.38006
MA0091.10.315003
MA0092.10.274547
MA0093.10.179936
MA0095.10
MA0098.10
MA0100.10.379666
MA0101.10.240622
MA0103.10.19444
MA0105.10.226879
MA0106.16.61172
MA0107.10.189625
MA0108.20.557195
MA0109.10
MA0111.10.78079
MA0113.10.452439
MA0114.10.400482
MA0115.10.805567
MA0116.10.165534
MA0117.10.774259
MA0119.10.676816
MA0122.10.793507
MA0124.10.992825
MA0125.10.920215
MA0130.10
MA0131.10.531427
MA0132.10
MA0133.10
MA0135.10.838263
MA0136.10.408073
MA0139.10.297344
MA0140.10.379562
MA0141.10.603844
MA0142.10.604892
MA0143.10.467531
MA0144.10.129525
MA0145.10.0257706
MA0146.10.266418
MA0147.10.138228
MA0148.10.851609
MA0149.12.75689
MA0062.20.0662974
MA0035.20.383789
MA0039.20.00920605
MA0138.20.523978
MA0002.20.302282
MA0137.20.598347
MA0104.20.326825
MA0047.20.431964
MA0112.20.025769
MA0065.20.4963
MA0150.10.290598
MA0151.10
MA0152.10.432062
MA0153.10.854464
MA0154.10.670722
MA0155.10.0312913
MA0156.10.200311
MA0157.10.574484
MA0158.10
MA0159.10.145521
MA0160.10.320315
MA0161.10
MA0162.10.0257461
MA0163.10.692813
MA0164.10.408402
MA0080.20.190316
MA0018.20.417217
MA0099.20.518072
MA0079.21.35452
MA0102.21.42135
MA0258.10.118033
MA0259.10.408856
MA0442.10