UBERON:0002532
From FANTOM5_SSTAR
| Name: | epiblast (generic) | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]" [Wikipedia:Epiblast, ZFIN:curator] | ||
| Xrefs: |
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| Synonyms: |
"blastocyst" RELATED [] "ectoblast" RELATED [MP:0003886] "epiblastus" RELATED LATIN [Wikipedia:Epiblast] "primitive ectoderm" RELATED [VHOG:0000243] | ||
| Comments: | MP says - tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper. In HOG, epiblast is part of primitive streak/blastpore, which is inconsistent with the MP definition of primitive streak as a ridge of the epiblast. Note that these terms, epiblast and hypoblast, are also used to describe layers of the avian embryonic blastoderm, but the layers so-named seem to be altogether different in these two kinds of vertebrate embryos(CVS). Consider obsoleting this as a grouping class | ||
| Alt_id: | UBERON:MIAA_0000067-ZFA_0000018 | ||
| Subset: |
early_development grouping_class uberon_slim vertebrate_core |
Gray21.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0002050(embryonic structure) |
|---|
Children
| is a: | UBERON:0008780 (inner cell mass derived epiblast) |
|---|---|
| develops from: | UBERON:0000923 (germ layer),UBERON:0010316 (germ layer / neural crest) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002532 (epiblast (generic)), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 7.5e-31 | FFCP PHASE1:Hg19::chr20:23618584..23618603,-#_4e3ee18b06bf09a4cfc09653af000bd0 | p1@CST3 |
| 7.5e-31 | FFCP PHASE2:Hg19::chr20:23618584..23618603,-#_4e3ee18b06bf09a4cfc09653af000bd0 | p1@CST3 |
| 6.91e-29 | FFCP PHASE1:Hg19::chr13:77460532..77460548,-#_2b97e8c4198931b6e8e4ead92a5be977 | p1@KCTD12 |
| 6.91e-29 | FFCP PHASE2:Hg19::chr13:77460532..77460548,-#_2b97e8c4198931b6e8e4ead92a5be977 | p1@KCTD12 |
| 1.31e-28 | FFCP PHASE1:Hg19::chr13:45010939..45011033,-#_0972aa4510ed521af60abb12b7373a9c | p1@TSC22D1 |
| 1.31e-28 | FFCP PHASE2:Hg19::chr13:45010939..45011033,-#_0972aa4510ed521af60abb12b7373a9c | p1@TSC22D1 |
| 6.82e-28 | FFCP PHASE2:Hg19::chr2:230135937..230136016,-#_f80d1913823a2c6cc68101e71f8d79d9 | p1@PID1 |
| 6.82e-28 | FFCP PHASE1:Hg19::chr2:230135937..230136016,-#_f80d1913823a2c6cc68101e71f8d79d9 | p1@PID1 |
| 1.74e-26 | FFCP PHASE1:Hg19::chr7:111846435..111846471,-#_09186355d523945b6ed38c5e71965984 | p1@DOCK4 |
| 1.74e-26 | FFCP PHASE2:Hg19::chr7:111846435..111846471,-#_09186355d523945b6ed38c5e71965984 | p1@DOCK4 |
| 4.12e-26 | FFCP PHASE1:Hg19::chr11:1330834..1330875,-#_4056ab206f41590a6495e17e9354ac0e | p1@TOLLIP |
| 4.12e-26 | FFCP PHASE2:Hg19::chr11:1330834..1330875,-#_4056ab206f41590a6495e17e9354ac0e | p1@TOLLIP |
| 6.68e-25 | FFCP PHASE1:Hg19::chr12:112204714..112204781,+#_425caf8f5b84e56b61c9d64887e31111 | p1@ALDH2 |
| 6.68e-25 | FFCP PHASE2:Hg19::chr12:112204714..112204781,+#_425caf8f5b84e56b61c9d64887e31111 | p1@ALDH2 |
| 6.83e-25 | FFCP PHASE1:Hg19::chr13:77460594..77460613,-#_cd0f87def87d0ffc79918f23da26e253 | p3@KCTD12 |
| 6.83e-25 | FFCP PHASE2:Hg19::chr13:77460594..77460613,-#_cd0f87def87d0ffc79918f23da26e253 | p3@KCTD12 |
| 1.27e-24 | FFCP PHASE1:Hg19::chr4:85887789..85887862,-#_030041dd5a34be9d4927c80b94eaae89 | p1@WDFY3 |
| 1.27e-24 | FFCP PHASE2:Hg19::chr4:85887789..85887862,-#_030041dd5a34be9d4927c80b94eaae89 | p1@WDFY3 |
| 6.07e-24 | FFCP PHASE1:Hg19::chr16:4852616..4852679,-#_59e829c6b55b1e5a3fad88b725fba6f8 | p1@ROGDI |
| 6.07e-24 | FFCP PHASE2:Hg19::chr16:4852616..4852679,-#_59e829c6b55b1e5a3fad88b725fba6f8 | p1@ROGDI |
| 1.62e-23 | FFCP PHASE2:Hg19::chr1:183774240..183774270,+#_727ecc3909bfcadda08663f9140bdd6b | p1@RGL1 |
| 1.62e-23 | FFCP PHASE1:Hg19::chr1:183774240..183774270,+#_727ecc3909bfcadda08663f9140bdd6b | p1@RGL1 |
| 2.33e-23 | FFCP PHASE2:Hg19::chr8:30670289..30670354,-#_43d098d6a8c0d55612f2b9a4b5382b4c | p1@PPP2CB |
| 2.33e-23 | FFCP PHASE1:Hg19::chr8:30670289..30670354,-#_43d098d6a8c0d55612f2b9a4b5382b4c | p1@PPP2CB |
| 2.57e-23 | FFCP PHASE1:Hg19::chr13:77460635..77460654,-#_5bd8b19da60403995e1323e3de693f14 | p2@KCTD12 |
| 2.57e-23 | FFCP PHASE2:Hg19::chr13:77460635..77460654,-#_5bd8b19da60403995e1323e3de693f14 | p2@KCTD12 |
| 4.06e-23 | FFCP PHASE2:Hg19::chr4:159094160..159094185,-#_a9d557c2b6abe3917d422c9d1806ef09 | p2@FAM198B |
| 4.06e-23 | FFCP PHASE1:Hg19::chr4:159094160..159094185,-#_a9d557c2b6abe3917d422c9d1806ef09 | p2@FAM198B |
| 6.15e-23 | FFCP PHASE1:Hg19::chr15:90456156..90456198,-#_0cded6fba9152a11f68dbf9ea85c6df7 | p1@C15orf38 |
| 6.15e-23 | FFCP PHASE2:Hg19::chr15:90456156..90456198,-#_0cded6fba9152a11f68dbf9ea85c6df7 | p1@C15orf38 |
| 7.82e-23 | FFCP PHASE2:Hg19::chr19:40871734..40871809,+#_0338e5632c182e507611f8eb4a6b3216 | p1@PLD3 |
| 7.82e-23 | FFCP PHASE1:Hg19::chr19:40871734..40871809,+#_0338e5632c182e507611f8eb4a6b3216 | p1@PLD3 |
| 1.53e-22 | FFCP PHASE1:Hg19::chr16:2563989..2564006,+#_85d329fc99de046ad85445ae629d094d | p2@ATP6V0C |
| 1.53e-22 | FFCP PHASE2:Hg19::chr16:2563989..2564006,+#_85d329fc99de046ad85445ae629d094d | p2@ATP6V0C |
| 2.37e-22 | FFCP PHASE2:Hg19::chr20:35974484..35974529,+#_218bfca014d496e80bb51a109201ff94 | p2@SRC |
| 2.37e-22 | FFCP PHASE1:Hg19::chr20:35974484..35974529,+#_218bfca014d496e80bb51a109201ff94 | p2@SRC |
| 5.65e-22 | FFCP PHASE1:Hg19::chr11:65082349..65082378,+#_39f656c6ea7a1a64412b4c9b93ca1010 | p1@CDC42EP2 |
| 5.65e-22 | FFCP PHASE2:Hg19::chr11:65082349..65082378,+#_39f656c6ea7a1a64412b4c9b93ca1010 | p1@CDC42EP2 |
| 5.66e-22 | FFCP PHASE1:Hg19::chr17:1466030..1466129,-#_34bda6e8a79d961992346c843b384e1e | p1@PITPNA |
| 5.66e-22 | FFCP PHASE2:Hg19::chr17:1466030..1466129,-#_34bda6e8a79d961992346c843b384e1e | p1@PITPNA |
| 5.93e-22 | FFCP PHASE2:Hg19::chr19:6720653..6720670,-#_b174908955fdcc5de672116e93a7ee45 | p1@C3 |
| 5.93e-22 | FFCP PHASE1:Hg19::chr19:6720653..6720670,-#_b174908955fdcc5de672116e93a7ee45 | p1@C3 |
| 6.18e-22 | FFCP PHASE1:Hg19::chr7:2671611..2671658,+#_22b22779706208d2d583538b84526565 | p2@TTYH3 |
| 6.18e-22 | FFCP PHASE2:Hg19::chr7:2671611..2671658,+#_22b22779706208d2d583538b84526565 | p2@TTYH3 |
| 1.1e-21 | FFCP PHASE1:Hg19::chr2:127864839..127864888,-#_916eb9612dafd3a5fcce8b731724ecb7 | p2@BIN1 |
| 1.1e-21 | FFCP PHASE2:Hg19::chr2:127864839..127864888,-#_916eb9612dafd3a5fcce8b731724ecb7 | p2@BIN1 |
| 2.41e-21 | FFCP PHASE1:Hg19::chr17:73851380..73851427,-#_cfa959015e08db382b94704d7caa9fb0 | p1@WBP2 |
| 2.41e-21 | FFCP PHASE2:Hg19::chr17:73851380..73851427,-#_cfa959015e08db382b94704d7caa9fb0 | p1@WBP2 |
| 3.59e-21 | FFCP PHASE2:Hg19::chr22:31003154..31003188,+#_c05fa96e242e059b8f9dff2ebbd1972d | p1@TCN2 |
| 3.59e-21 | FFCP PHASE1:Hg19::chr22:31003154..31003188,+#_c05fa96e242e059b8f9dff2ebbd1972d | p1@TCN2 |
| 3.69e-21 | FFCP PHASE2:Hg19::chr9:14314566..14314618,-#_b3eeea4c6fb3385de558e2aa5b84a838 | p1@NFIB |
| 3.69e-21 | FFCP PHASE1:Hg19::chr9:14314566..14314618,-#_b3eeea4c6fb3385de558e2aa5b84a838 | p1@NFIB |
| 4.02e-21 | FFCP PHASE1:Hg19::chr9:14314131..14314147,-#_ae1fea3e6e5859faec6e79998c07ea32 | p2@NFIB |
| 4.02e-21 | FFCP PHASE2:Hg19::chr9:14314131..14314147,-#_ae1fea3e6e5859faec6e79998c07ea32 | p2@NFIB |
| 4.54e-21 | FFCP PHASE1:Hg19::chr19:44100155..44100211,-#_b37489456cb7b1f7056740a993726d13 | p1@IRGQ |
| 4.54e-21 | FFCP PHASE2:Hg19::chr19:44100155..44100211,-#_b37489456cb7b1f7056740a993726d13 | p1@IRGQ |
| 5.7e-21 | FFCP PHASE1:Hg19::chr4:24914581..24914691,-#_d307d1c9755a2ec8bd108a8b61f955a4 | p1@CCDC149 |
| 5.7e-21 | FFCP PHASE2:Hg19::chr4:24914581..24914691,-#_d307d1c9755a2ec8bd108a8b61f955a4 | p1@CCDC149 |
| 6.27e-21 | FFCP PHASE1:Hg19::chr2:127864608..127864688,-#_2386ff2dba52df2f4165c400d72e404c | p1@BIN1 |
| 6.27e-21 | FFCP PHASE2:Hg19::chr2:127864608..127864688,-#_2386ff2dba52df2f4165c400d72e404c | p1@BIN1 |
| 1.02e-20 | FFCP PHASE2:Hg19::chr19:14228541..14228582,-#_edc0a8183c6493f28d7daa057fce97da | p1@PRKACA |
| 1.02e-20 | FFCP PHASE1:Hg19::chr19:14228541..14228582,-#_edc0a8183c6493f28d7daa057fce97da | p1@PRKACA |
| 1.29e-20 | FFCP PHASE1:Hg19::chr16:89787269..89787359,-#_b529e790080c5abb79ee8a8d852ba877 | p1@C16orf7 |
| 1.29e-20 | FFCP PHASE2:Hg19::chr16:89787269..89787359,-#_b529e790080c5abb79ee8a8d852ba877 | p1@C16orf7 |
| 1.45e-20 | FFCP PHASE2:Hg19::chr1:10270620..10270637,+#_1d852043cf3a2191256be41478265a2c | p1@KIF1B |
| 1.45e-20 | FFCP PHASE1:Hg19::chr1:10270620..10270637,+#_1d852043cf3a2191256be41478265a2c | p1@KIF1B |
| 2.63e-20 | FFCP PHASE1:Hg19::chr18:59561635..59561651,-#_5b5c8761e74587d0362b6e71c9c80285 | p@chr18:59561635..59561651, - |
| 2.63e-20 | FFCP PHASE2:Hg19::chr18:59561635..59561651,-#_5b5c8761e74587d0362b6e71c9c80285 | p@chr18:59561635..59561651, - |
| 3.08e-20 | FFCP PHASE1:Hg19::chr12:52345448..52345532,+#_1ceaeb396aecd4e91a922fe63946f127 | p1@ACVR1B |
| 3.08e-20 | FFCP PHASE2:Hg19::chr12:52345448..52345532,+#_1ceaeb396aecd4e91a922fe63946f127 | p1@ACVR1B |
| 3.96e-20 | FFCP PHASE1:Hg19::chr20:23614485..23614564,-#_7a336af03d6701fcd85b51a2d631a41f | p@chr20:23614485..23614564, - |
| 3.96e-20 | FFCP PHASE2:Hg19::chr20:23614485..23614564,-#_7a336af03d6701fcd85b51a2d631a41f | p@chr20:23614485..23614564, - |
| 5.35e-20 | FFCP PHASE2:Hg19::chr1:68698197..68698214,-#_9d8c0844192b84df3332fee3dc2be3c2 | p1@WLS |
| 5.35e-20 | FFCP PHASE1:Hg19::chr1:68698197..68698214,-#_9d8c0844192b84df3332fee3dc2be3c2 | p1@WLS |
| 6.51e-20 | FFCP PHASE1:Hg19::chr10:30025922..30025958,-#_ad008731cba1f2eaf6ebd2380dcd977b | p3@SVIL |
| 6.51e-20 | FFCP PHASE2:Hg19::chr10:30025922..30025958,-#_ad008731cba1f2eaf6ebd2380dcd977b | p3@SVIL |
| 6.99e-20 | FFCP PHASE1:Hg19::chr15:64995399..64995422,-#_0d8491794eedbfd76e5c42e52716d9ee | p1@OAZ2 |
| 6.99e-20 | FFCP PHASE2:Hg19::chr15:64995399..64995422,-#_0d8491794eedbfd76e5c42e52716d9ee | p1@OAZ2 |
| 8.06e-20 | FFCP PHASE1:Hg19::chr9:34989685..34989748,+#_abe5a92c63500c16217dc45b79822b2d | p1@DNAJB5 |
| 8.06e-20 | FFCP PHASE2:Hg19::chr9:34989685..34989748,+#_abe5a92c63500c16217dc45b79822b2d | p1@DNAJB5 |
| 9.9e-20 | FFCP PHASE1:Hg19::chrX:100333858..100333876,+#_a76c4871575b9092a8e7287b32ae8aea | p1@TMEM35 |
| 9.9e-20 | FFCP PHASE2:Hg19::chrX:100333858..100333876,+#_a76c4871575b9092a8e7287b32ae8aea | p1@TMEM35 |
| 1.09e-19 | FFCP PHASE1:Hg19::chr16:2563941..2563983,+#_f58d1eca29e7639361c5ebc19d7c6845 | p1@ATP6V0C |
| 1.09e-19 | FFCP PHASE2:Hg19::chr16:2563941..2563983,+#_f58d1eca29e7639361c5ebc19d7c6845 | p1@ATP6V0C |
| 1.11e-19 | FFCP PHASE1:Hg19::chr17:68165657..68165688,+#_e761e14b2d4034657f80b9c3689568f1 | p1@KCNJ2 |
| 1.11e-19 | FFCP PHASE2:Hg19::chr17:68165657..68165688,+#_e761e14b2d4034657f80b9c3689568f1 | p1@KCNJ2 |
| 1.12e-19 | FFCP PHASE1:Hg19::chr17:7492684..7492778,-#_ab96814bfe67a7f4832dc2912085565c | p2@SOX15 |
| 1.12e-19 | FFCP PHASE2:Hg19::chr17:7492684..7492778,-#_ab96814bfe67a7f4832dc2912085565c | p2@SOX15 |
| 1.16e-19 | FFCP PHASE2:Hg19::chr19:11466086..11466159,+#_ef63dbed3e6fabceacadb2f19cc13459 | p1@LPPR2 |
| 1.16e-19 | FFCP PHASE1:Hg19::chr19:11466086..11466159,+#_ef63dbed3e6fabceacadb2f19cc13459 | p1@LPPR2 |
| 1.32e-19 | FFCP PHASE2:Hg19::chr18:59561658..59561685,-#_43631c3e3dfdef3d5a893779b22a8cc8 | p@chr18:59561658..59561685, - |
| 1.32e-19 | FFCP PHASE1:Hg19::chr18:59561658..59561685,-#_43631c3e3dfdef3d5a893779b22a8cc8 | p@chr18:59561658..59561685, - |
| 1.38e-19 | FFCP PHASE1:Hg19::chr12:110719036..110719113,+#_456c737cd8a5b1e3ac4cafbf2ae3b0d6 | p1@ATP2A2 |
| 1.38e-19 | FFCP PHASE2:Hg19::chr12:110719036..110719113,+#_456c737cd8a5b1e3ac4cafbf2ae3b0d6 | p1@ATP2A2 |
| 1.45e-19 | FFCP PHASE1:Hg19::chr6:123110389..123110441,+#_fb327e0bde48a1f24ec2f04cb6239f04 | p1@SMPDL3A |
| 1.45e-19 | FFCP PHASE2:Hg19::chr6:123110389..123110441,+#_fb327e0bde48a1f24ec2f04cb6239f04 | p1@SMPDL3A |
| 1.86e-19 | FFCP PHASE1:Hg19::chr10:118764649..118764683,-#_8d954ea905a5aca6543e4e97bd93018a | p2@KIAA1598 |
| 1.86e-19 | FFCP PHASE2:Hg19::chr10:118764649..118764683,-#_8d954ea905a5aca6543e4e97bd93018a | p2@KIAA1598 |
| 3.3e-19 | FFCP PHASE2:Hg19::chr2:153191678..153191697,+#_43996d591c7acbb5b45bd93e885f5966 | p1@FMNL2 |
| 3.3e-19 | FFCP PHASE1:Hg19::chr2:153191678..153191697,+#_43996d591c7acbb5b45bd93e885f5966 | p1@FMNL2 |
