Personal tools

MCL coexpression mm9:369: Difference between revisions

From FANTOM5_SSTAR

Jump to: navigation, search
No edit summary
No edit summary
Line 6: Line 6:
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000160!2.51e-14!31;UBERON:0005409!4.67e-14!47;UBERON:0005172!1.49e-12!49;UBERON:0005173!1.49e-12!49;UBERON:0002417!1.49e-12!49;UBERON:0000916!1.49e-12!49;UBERON:0002365!5.11e-12!25;UBERON:0002330!5.11e-12!25;UBERON:0005177!5.15e-12!79;UBERON:0004119!1.02e-11!118;UBERON:0000925!1.02e-11!118;UBERON:0006595!1.02e-11!118;UBERON:0009854!1.36e-11!23;UBERON:0009856!1.36e-11!23;UBERON:0001007!1.80e-11!116;UBERON:0001555!1.80e-11!116;UBERON:0007026!1.80e-11!116;UBERON:0002107!3.81e-11!22;UBERON:0007499!3.81e-11!22;UBERON:0006925!3.81e-11!22;UBERON:0009497!3.81e-11!22;UBERON:0000015!3.81e-11!22;UBERON:0002423!3.81e-11!22;UBERON:0006235!3.81e-11!22;UBERON:0008835!3.81e-11!22;UBERON:0003894!3.81e-11!22;UBERON:0004161!3.81e-11!22;UBERON:0008836!3.81e-11!22;UBERON:0004921!1.26e-10!114;UBERON:0000344!8.29e-10!15;UBERON:0002100!5.76e-09!90;UBERON:0009569!7.44e-09!66;UBERON:0001242!8.99e-09!13;UBERON:0000060!8.99e-09!13;UBERON:0001262!8.99e-09!13;UBERON:0004786!8.99e-09!13;UBERON:0003104!2.85e-08!61;UBERON:0009142!2.85e-08!61;UBERON:0000466!3.09e-08!79;UBERON:0004923!2.17e-07!24;UBERON:0005256!2.47e-07!45
|ontology_enrichment_uberon=UBERON:0000160!2.51e-14!31;UBERON:0005409!4.67e-14!47;UBERON:0005172!1.49e-12!49;UBERON:0005173!1.49e-12!49;UBERON:0002417!1.49e-12!49;UBERON:0000916!1.49e-12!49;UBERON:0002365!5.11e-12!25;UBERON:0002330!5.11e-12!25;UBERON:0005177!5.15e-12!79;UBERON:0004119!1.02e-11!118;UBERON:0000925!1.02e-11!118;UBERON:0006595!1.02e-11!118;UBERON:0009854!1.36e-11!23;UBERON:0009856!1.36e-11!23;UBERON:0001007!1.80e-11!116;UBERON:0001555!1.80e-11!116;UBERON:0007026!1.80e-11!116;UBERON:0002107!3.81e-11!22;UBERON:0007499!3.81e-11!22;UBERON:0006925!3.81e-11!22;UBERON:0009497!3.81e-11!22;UBERON:0000015!3.81e-11!22;UBERON:0002423!3.81e-11!22;UBERON:0006235!3.81e-11!22;UBERON:0008835!3.81e-11!22;UBERON:0003894!3.81e-11!22;UBERON:0004161!3.81e-11!22;UBERON:0008836!3.81e-11!22;UBERON:0004921!1.26e-10!114;UBERON:0000344!8.29e-10!15;UBERON:0002100!5.76e-09!90;UBERON:0009569!7.44e-09!66;UBERON:0001242!8.99e-09!13;UBERON:0000060!8.99e-09!13;UBERON:0001262!8.99e-09!13;UBERON:0004786!8.99e-09!13;UBERON:0003104!2.85e-08!61;UBERON:0009142!2.85e-08!61;UBERON:0000466!3.09e-08!79;UBERON:0004923!2.17e-07!24;UBERON:0005256!2.47e-07!45
|tfbs_overrepresentation_for_novel_motifs=0.403818,0.534014,0.364203,0.469866,0.458154,0.164217,0.644497,0.766372,0.0267199,0.243837,0.570169,0.218542,1.12096,0.23628,0.855559,0,1.01097,0.0539173,0.225105,0.794788,0.0932143,0.362751,0.235613,0.790844,0.37554,2.03034,0.0827016,1.01147,0.566523,0.487282,0.168752,0.476579,0.0529999,0.348165,0.498491,0.56272,0.413492,0.617803,0.159542,0.304085,0.0555312,0.512679,0.186867,0.232623,0.224221,1.42394,0.323935,1.0546,0.025795,0.573736,0.374992,0.760562,0.266413,1.4683,0.619345,0.677917,0.0837141,0.209397,0.194113,0.67439,0.459084,0.777251,0.862507,0.958213,1.99405,1.03267,0.745869,1.08074,0.455021,0.938231,1.13692,0.792871,0.392313,0.650163,0.0701313,1.98208,0.34796,0.314806,0.444191,0.0954455,0.79827,1.04303,0.283653,0.0973679,0.545133,0.646822,4.74073,0.0508374,0.327889,1.23935,0.811671,0.549603,0.487824,0.0597386,1.90152,0.580811,0.248387,2.12881,0.324141,0.909992,0.0493173,0.476334,0.58753,0.375488,0.978012,0.171895,1.08837,0.546657,0.664746,1.07708,0.393011,0.58915,0.318143,0.199544,0.818358,0.20155,1.12275,0.157255,0.390716,0.0478434,0.655146,0.919978,0.258253,0.314081,0.869916,0.447391,0.233251,1.21067,0.744444,0.478953,0.572132,0.896011,0.716744,0.251791,0.838892,0.542152,1.33798,0.17313,0.792231,1.60311,1.2081,0.750296,0.267427,0.48577,0.369214,0.513419,0.326451,1.56378,0.135184,1.22075,1.43712,0.487074,0.60483,0.331339,0.251095,0.680035,0.76234,0.0699281,0.127194,0.825084,0.801233,0.544365,0.447776,0.779273,0.366469,0.245542,0.410962,0.217399,0.660742
}}
}}

Revision as of 18:15, 26 November 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:120353209..120353235,+p1@Slc25a10
Mm9::chr11:120353243..120353263,+p3@Slc25a10
Mm9::chr11:96891239..96891311,+p1@Scrn2
Mm9::chr13:54167229..54167278,+p1@Sfxn1
Mm9::chr17:12868652..12868673,-p4@Slc22a1
Mm9::chr19:44144226..44144277,-p1@Erlin1
Mm9::chr19:44181916..44181931,-p2@Chuk
Mm9::chr1:133693960..133693995,+p1@Pm20d1
Mm9::chr1:13658820..13658853,+p1@Xkr9
Mm9::chr1:13659082..13659121,+p@chr1:13659082..13659121
+
Mm9::chr1:169280107..169280196,+p2@Aldh9a1
Mm9::chr1:169280315..169280365,+p1@Aldh9a1
Mm9::chr1:169280377..169280380,+p@chr1:169280377..169280380
+
Mm9::chr1:59030534..59030545,+p6@Stradb
Mm9::chr1:59030546..59030561,+p7@Stradb
Mm9::chr1:93339454..93339482,+p@chr1:93339454..93339482
+
Mm9::chr4:154937907..154937974,+p1@Nadk
Mm9::chr5:31223940..31223956,+p4@Khk
Mm9::chr5:31224198..31224239,+p2@Khk
Mm9::chr5:31224240..31224269,+p1@Khk
Mm9::chr6:137703123..137703129,+p2@Dera


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0019145aminobutyraldehyde dehydrogenase activity0.0359392976497014
GO:0004139deoxyribose-phosphate aldolase activity0.0359392976497014
GO:0004454ketohexokinase activity0.0359392976497014
GO:0003951NAD+ kinase activity0.0461798253473553
GO:0030099myeloid cell differentiation0.0461798253473553
GO:0007252I-kappaB phosphorylation0.0461798253473553
GO:0008384IkappaB kinase activity0.0461798253473553
GO:0009264deoxyribonucleotide catabolic process0.0478757600170195
GO:0009437carnitine metabolic process0.0478757600170195



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
epithelial cell5.95e-0725

Uber Anatomy
Ontology termp-valuen
intestine2.51e-1431
gastrointestinal system4.67e-1447
abdomen element1.49e-1249
abdominal segment element1.49e-1249
abdominal segment of trunk1.49e-1249
abdomen1.49e-1249
exocrine gland5.11e-1225
exocrine system5.11e-1225
trunk region element5.15e-1279
endoderm-derived structure1.02e-11118
endoderm1.02e-11118
presumptive endoderm1.02e-11118
digestive tract diverticulum1.36e-1123
sac1.36e-1123
digestive system1.80e-11116
digestive tract1.80e-11116
primitive gut1.80e-11116
liver3.81e-1122
epithelial sac3.81e-1122
digestive gland3.81e-1122
epithelium of foregut-midgut junction3.81e-1122
anatomical boundary3.81e-1122
hepatobiliary system3.81e-1122
foregut-midgut junction3.81e-1122
hepatic diverticulum3.81e-1122
liver primordium3.81e-1122
septum transversum3.81e-1122
liver bud3.81e-1122
subdivision of digestive tract1.26e-10114
mucosa8.29e-1015
trunk5.76e-0990
subdivision of trunk7.44e-0966
intestinal mucosa8.99e-0913
anatomical wall8.99e-0913
wall of intestine8.99e-0913
gastrointestinal system mucosa8.99e-0913
mesenchyme2.85e-0861
entire embryonic mesenchyme2.85e-0861
immaterial anatomical entity3.09e-0879
organ component layer2.17e-0724
trunk mesenchyme2.47e-0745


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}