MCL coexpression mm9:509

Phase1 CAGE Peaks

	Short description
Mm9::chr10:20032267..20032298,+	p1@Bclaf1
Mm9::chr10:30320468..30320507,-	p1@Trmt11
Mm9::chr11:83286581..83286625,+	p1@Taf15
Mm9::chr16:98303146..98303177,-	p1@A630089N07Rik
Mm9::chr1:58449963..58449991,+	p1@Bzw1
Mm9::chr2:139996264..139996305,-	p1@Esf1
Mm9::chr2:69560854..69560897,+	p1@Ppig
Mm9::chr2:69699642..69699692,+	p1@Ssb
Mm9::chr2:75497310..75497323,+	p1@Gm11847 p1@Hnrnpa3 p1@LOC100504930 p1@LOC100505153 p1@LOC100505318
Mm9::chr4:134909041..134909072,-	p1@Srrm1
Mm9::chr6:51419835..51419853,-	p1@Hnrnpa2b1 p1@LOC100045191
Mm9::chr9:95412276..95412311,-	p1@2610101N10Rik
Mm9::chrX:148450978..148451061,+	p1@Smc1a
Mm9::chrX:46048227..46048272,+	p1@Rbmx2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0003676	nucleic acid binding	0.000132674954062797
GO:0003723	RNA binding	0.00116200650109324
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.00116200650109324
GO:0016070	RNA metabolic process	0.00116200650109324
GO:0006396	RNA processing	0.00217965357397562
GO:0010467	gene expression	0.00289657235911795
GO:0044237	cellular metabolic process	0.00473553114394023
GO:0043283	biopolymer metabolic process	0.00655461103996711
GO:0043170	macromolecule metabolic process	0.00767170497479986
GO:0044238	primary metabolic process	0.0244127424594363
GO:0030529	ribonucleoprotein complex	0.0418820546813995

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
primordium	6.99e-11	134
anterior region of body	5.61e-10	43
hemopoietic organ	6.88e-09	29
immune organ	6.88e-09	29
craniocervical region	6.34e-08	36
foregut	1.68e-07	80
thymus	6.07e-07	23
neck	6.07e-07	23
respiratory system epithelium	6.07e-07	23
hemolymphoid system gland	6.07e-07	23
pharyngeal epithelium	6.07e-07	23
thymic region	6.07e-07	23
pharyngeal gland	6.07e-07	23
entire pharyngeal arch endoderm	6.07e-07	23
thymus primordium	6.07e-07	23
early pharyngeal endoderm	6.07e-07	23
mixed endoderm/mesoderm-derived structure	6.43e-07	35
respiratory tract	8.24e-07	41

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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