Coexpression cluster:C577: Difference between revisions
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{{Coexpression_clusters | {{Coexpression_clusters|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.16390060743717,0.066028034726785,0.118873939973783,0,0,0,0,0,0,0.7146003826757,0.495896415571773,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.18924842580987,0,0.154341861042433,0.146250857583845,0.197212289927417,0.220381364985783,0.290936506658587,0.330094213592205,0.33735429485416,0.246633096772289,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.137229487140467,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.424506527225336,0,0,0.136484150373336,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.135103881494694,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.656288497594363,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.128948885815716,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.10787168088319,0.0526615420969484,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0271819376754428,0.0261550693490902,0,0,0,0,0,0.223631044494439,0,0,0,0,0,0,0,0,0,0,0.0796420028184954,0.12076093114532|full_id=C577_lymphoma_Burkitt_diffuse_b_myeloma_plasma_appendix|gostat_on_coexpression_clusters=GO:0051649!establishment of cellular localization!0.00552662192040757!7456;7277;4033;3507$GO:0051641!cellular localization!0.00552662192040757!7456;7277;4033;3507$GO:0042571!immunoglobulin complex, circulating!0.0192416604751251!3507$GO:0007010!cytoskeleton organization and biogenesis!0.0192416604751251!7456;7277;4033$GO:0019814!immunoglobulin complex!0.0216076366368423!3507$GO:0045022!early endosome to late endosome transport!0.0216076366368423!3507$GO:0019815!B cell receptor complex!0.0216076366368423!3507$GO:0046907!intracellular transport!0.0216076366368423!7456;7277;3507$GO:0030705!cytoskeleton-dependent intracellular transport!0.0216076366368423!7456;7277$GO:0006906!vesicle fusion!0.0234837102650863!4033$GO:0005522!profilin binding!0.026683677801369!7456$GO:0000702!oxidized base lesion DNA N-glycosylase activity!0.0270918033101799!79661$GO:0008534!oxidized purine base lesion DNA N-glycosylase activity!0.0270918033101799!79661$GO:0016044!membrane organization and biogenesis!0.0273904043885752!4033;3507$GO:0007516!hemocyte development!0.0273904043885752!4033$GO:0042386!hemocyte differentiation!0.0277973802242663!4033$GO:0007017!microtubule-based process!0.0277973802242663!7277;4033$GO:0003906!DNA-(apurinic or apyrimidinic site) lyase activity!0.0277973802242663!79661$GO:0030890!positive regulation of B cell proliferation!0.0277973802242663!3507$GO:0006903!vesicle targeting!0.0279419887118174!4033$GO:0030888!regulation of B cell proliferation!0.0279419887118174!3507$GO:0050853!B cell receptor signaling pathway!0.0280609975354872!3507$GO:0051650!establishment of vesicle localization!0.0280609975354872!4033$GO:0016043!cellular component organization and biogenesis!0.0281605506756081!7456;7277;4033;3507$GO:0051648!vesicle localization!0.0281605506756081!4033$GO:0006996!organelle organization and biogenesis!0.0302840317239506!7456;7277;4033$GO:0005622!intracellular!0.0310429794423133!7456;7277;4012;79661;57504;4033;3507$GO:0030048!actin filament-based movement!0.0310429794423133!7456$GO:0001772!immunological synapse!0.0310429794423133!3507$GO:0050731!positive regulation of peptidyl-tyrosine phosphorylation!0.0310429794423133!3507$GO:0050871!positive regulation of B cell activation!0.0310429794423133!3507$GO:0045807!positive regulation of endocytosis!0.0310429794423133!3507$GO:0042100!B cell proliferation!0.0310429794423133!3507$GO:0019104!DNA N-glycosylase activity!0.0310429794423133!79661$GO:0051656!establishment of organelle localization!0.0331805783503322!4033$GO:0042327!positive regulation of phosphorylation!0.0331805783503322!3507$GO:0016799!hydrolase activity, hydrolyzing N-glycosyl compounds!0.0331805783503322!79661$GO:0045937!positive regulation of phosphate metabolic process!0.0331805783503322!3507$GO:0050864!regulation of B cell activation!0.0331805783503322!3507$GO:0006810!transport!0.0331805783503322!7456;7277;4033;3507$GO:0001934!positive regulation of protein amino acid phosphorylation!0.0331805783503322!3507$GO:0033240!positive regulation of amine metabolic process!0.0331805783503322!3507$GO:0045764!positive regulation of amino acid metabolic process!0.0331805783503322!3507$GO:0050851!antigen receptor-mediated signaling pathway!0.0331805783503322!3507$GO:0051234!establishment of localization!0.0331805783503322!7456;7277;4033;3507$GO:0050730!regulation of peptidyl-tyrosine phosphorylation!0.0331805783503322!3507$GO:0032946!positive regulation of mononuclear cell proliferation!0.0331805783503322!3507$GO:0002429!immune response-activating cell surface receptor signaling pathway!0.0331805783503322!3507$GO:0002455!humoral immune response mediated by circulating immunoglobulin!0.0331805783503322!3507$GO:0050671!positive regulation of lymphocyte proliferation!0.0331805783503322!3507$GO:0043170!macromolecule metabolic process!0.0331805783503322!7456;7277;4012;79661;57504;3507$GO:0016192!vesicle-mediated transport!0.0331805783503322!4033;3507$GO:0002768!immune response-regulating cell surface receptor signaling pathway!0.0331805783503322!3507$GO:0002757!immune response-activating signal transduction!0.0331805783503322!3507$GO:0004520!endodeoxyribonuclease activity!0.0331805783503322!79661$GO:0051640!organelle localization!0.0331805783503322!4033$GO:0002764!immune response-regulating signal transduction!0.0331805783503322!3507$GO:0004179!membrane alanyl aminopeptidase activity!0.0331805783503322!4012$GO:0030100!regulation of endocytosis!0.0331805783503322!3507$GO:0016284!alanine aminopeptidase activity!0.0331805783503322!4012$GO:0006284!base-excision repair!0.0335935694889657!79661$GO:0051179!localization!0.0343797278606345!7456;7277;4033;3507$GO:0006944!membrane fusion!0.0343797278606345!4033$GO:0051050!positive regulation of transport!0.0347541396382348!3507$GO:0016197!endosome transport!0.0357691233612271!3507$GO:0032944!regulation of mononuclear cell proliferation!0.0357691233612271!3507$GO:0018108!peptidyl-tyrosine phosphorylation!0.0357691233612271!3507$GO:0050670!regulation of lymphocyte proliferation!0.0357691233612271!3507$GO:0044459!plasma membrane part!0.0357691233612271!4012;4033;3507$GO:0006289!nucleotide-excision repair!0.035940294858417!79661$GO:0018212!peptidyl-tyrosine modification!0.036254941554881!3507$GO:0001932!regulation of protein amino acid phosphorylation!0.0363598696327606!3507$GO:0033238!regulation of amine metabolic process!0.0363598696327606!3507$GO:0006521!regulation of amino acid metabolic process!0.0363598696327606!3507$GO:0003684!damaged DNA binding!0.03774397245156!79661$GO:0009897!external side of plasma membrane!0.03774397245156!3507$GO:0004536!deoxyribonuclease activity!0.03774397245156!79661$GO:0016064!immunoglobulin mediated immune response!0.03774397245156!3507$GO:0051251!positive regulation of lymphocyte activation!0.03774397245156!3507$GO:0019724!B cell mediated immunity!0.037782428412284!3507$GO:0032943!mononuclear cell proliferation!0.037782428412284!3507$GO:0046651!lymphocyte proliferation!0.037782428412284!3507$GO:0000187!activation of MAPK activity!0.0401301956548925!3507$GO:0008154!actin polymerization and/or depolymerization!0.0419210442296136!7456$GO:0042113!B cell activation!0.0419210442296136!3507$GO:0044237!cellular metabolic process!0.0424084858387849!7456;7277;4012;79661;57504;3507$GO:0042325!regulation of phosphorylation!0.0424720760935587!3507$GO:0048471!perinuclear region of cytoplasm!0.0424720760935587!3507$GO:0044238!primary metabolic process!0.042725642634001!7456;7277;4012;79661;57504;3507$GO:0043406!positive regulation of MAP kinase activity!0.0428184511525644!3507$GO:0051174!regulation of phosphorus metabolic process!0.043780004563187!3507$GO:0019220!regulation of phosphate metabolic process!0.043780004563187!3507$GO:0044424!intracellular part!0.044082719341471!7456;7277;79661;57504;4033;3507$GO:0002253!activation of immune response!0.044082719341471!3507$GO:0002449!lymphocyte mediated immunity!0.0442291349268762!3507$GO:0006959!humoral immune response!0.0447841817368642!3507$GO:0002250!adaptive immune response!0.0447841817368642!3507$GO:0002460!adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains!0.0447841817368642!3507$GO:0051249!regulation of lymphocyte activation!0.0447841817368642!3507$GO:0002443!leukocyte mediated immunity!0.0454950552453424!3507$GO:0050865!regulation of cell activation!0.0461914459110638!3507$GO:0007565!female pregnancy!0.0463062344559114!4012$GO:0004177!aminopeptidase activity!0.0468465567744402!4012$GO:0050778!positive regulation of immune response!0.0468465567744402!3507$GO:0051247!positive regulation of protein metabolic process!0.0468465567744402!3507$GO:0044260!cellular macromolecule metabolic process!0.0468465567744402!7456;7277;4012;3507$GO:0002684!positive regulation of immune system 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0162.1;0.000900738,MA0163.1;0.0365728,MA0164.1;0.402162,MA0080.2;0.851709,MA0018.2;0.378086,MA0099.2;0.312108,MA0079.2;9.91681e-05,MA0102.2;1.1957,MA0258.1;0.964206,MA0259.1;1.1468,MA0442.1;0}} | ||
|full_id=C577_lymphoma_Burkitt_diffuse_b_myeloma_plasma_appendix | |||
|id=C577 | |||
}} |
Latest revision as of 11:26, 17 September 2013
Full id: C577_lymphoma_Burkitt_diffuse_b_myeloma_plasma_appendix
Phase1 CAGE Peaks
Hg19::chr10:11715600..11715620,+ | p1@uc001ikv.1 |
Hg19::chr12:25157568..25157581,+ | p@chr12:25157568..25157581 + |
Hg19::chr12:25205026..25205040,+ | p9@LRMP |
Hg19::chr14:106320502..106320513,- | p12@IGHM |
Hg19::chr15:59691821..59691828,+ | p@chr15:59691821..59691828 + |
Hg19::chr15:59705215..59705224,- | p@chr15:59705215..59705224 - |
Hg19::chr15:75639773..75639782,+ | p15@NEIL1 |
Hg19::chr18:56563687..56563711,+ | p@chr18:56563687..56563711 + |
Hg19::chr19:19281060..19281078,- | p2@MEF2BNB-MEF2B p2@MEF2B |
Hg19::chr2:175462951..175462965,- | p7@WIPF1 |
Hg19::chr2:220142900..220142916,- | p22@TUBA4A |
Hg19::chr2:42795391..42795403,+ | p17@MTA3 |
Hg19::chr2:64370395..64370418,+ | p1@ENST00000438115 |
Hg19::chr5:96293965..96293986,+ | p10@LNPEP |
Hg19::chr7:101923076..101923085,+ | p@chr7:101923076..101923085 + |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
No results for this coexpression
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0051649 | establishment of cellular localization | 0.00552662192040757 |
GO:0051641 | cellular localization | 0.00552662192040757 |
GO:0042571 | immunoglobulin complex, circulating | 0.0192416604751251 |
GO:0007010 | cytoskeleton organization and biogenesis | 0.0192416604751251 |
GO:0019814 | immunoglobulin complex | 0.0216076366368423 |
GO:0045022 | early endosome to late endosome transport | 0.0216076366368423 |
GO:0019815 | B cell receptor complex | 0.0216076366368423 |
GO:0046907 | intracellular transport | 0.0216076366368423 |
GO:0030705 | cytoskeleton-dependent intracellular transport | 0.0216076366368423 |
GO:0006906 | vesicle fusion | 0.0234837102650863 |
GO:0005522 | profilin binding | 0.026683677801369 |
GO:0000702 | oxidized base lesion DNA N-glycosylase activity | 0.0270918033101799 |
GO:0008534 | oxidized purine base lesion DNA N-glycosylase activity | 0.0270918033101799 |
GO:0016044 | membrane organization and biogenesis | 0.0273904043885752 |
GO:0007516 | hemocyte development | 0.0273904043885752 |
GO:0042386 | hemocyte differentiation | 0.0277973802242663 |
GO:0007017 | microtubule-based process | 0.0277973802242663 |
GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity | 0.0277973802242663 |
GO:0030890 | positive regulation of B cell proliferation | 0.0277973802242663 |
GO:0006903 | vesicle targeting | 0.0279419887118174 |
GO:0030888 | regulation of B cell proliferation | 0.0279419887118174 |
GO:0050853 | B cell receptor signaling pathway | 0.0280609975354872 |
GO:0051650 | establishment of vesicle localization | 0.0280609975354872 |
GO:0016043 | cellular component organization and biogenesis | 0.0281605506756081 |
GO:0051648 | vesicle localization | 0.0281605506756081 |
GO:0006996 | organelle organization and biogenesis | 0.0302840317239506 |
GO:0005622 | intracellular | 0.0310429794423133 |
GO:0030048 | actin filament-based movement | 0.0310429794423133 |
GO:0001772 | immunological synapse | 0.0310429794423133 |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 0.0310429794423133 |
GO:0050871 | positive regulation of B cell activation | 0.0310429794423133 |
GO:0045807 | positive regulation of endocytosis | 0.0310429794423133 |
GO:0042100 | B cell proliferation | 0.0310429794423133 |
GO:0019104 | DNA N-glycosylase activity | 0.0310429794423133 |
GO:0051656 | establishment of organelle localization | 0.0331805783503322 |
GO:0042327 | positive regulation of phosphorylation | 0.0331805783503322 |
GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds | 0.0331805783503322 |
GO:0045937 | positive regulation of phosphate metabolic process | 0.0331805783503322 |
GO:0050864 | regulation of B cell activation | 0.0331805783503322 |
GO:0006810 | transport | 0.0331805783503322 |
GO:0001934 | positive regulation of protein amino acid phosphorylation | 0.0331805783503322 |
GO:0033240 | positive regulation of amine metabolic process | 0.0331805783503322 |
GO:0045764 | positive regulation of amino acid metabolic process | 0.0331805783503322 |
GO:0050851 | antigen receptor-mediated signaling pathway | 0.0331805783503322 |
GO:0051234 | establishment of localization | 0.0331805783503322 |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 0.0331805783503322 |
GO:0032946 | positive regulation of mononuclear cell proliferation | 0.0331805783503322 |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 0.0331805783503322 |
GO:0002455 | humoral immune response mediated by circulating immunoglobulin | 0.0331805783503322 |
GO:0050671 | positive regulation of lymphocyte proliferation | 0.0331805783503322 |
GO:0043170 | macromolecule metabolic process | 0.0331805783503322 |
GO:0016192 | vesicle-mediated transport | 0.0331805783503322 |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 0.0331805783503322 |
GO:0002757 | immune response-activating signal transduction | 0.0331805783503322 |
GO:0004520 | endodeoxyribonuclease activity | 0.0331805783503322 |
GO:0051640 | organelle localization | 0.0331805783503322 |
GO:0002764 | immune response-regulating signal transduction | 0.0331805783503322 |
GO:0004179 | membrane alanyl aminopeptidase activity | 0.0331805783503322 |
GO:0030100 | regulation of endocytosis | 0.0331805783503322 |
GO:0016284 | alanine aminopeptidase activity | 0.0331805783503322 |
GO:0006284 | base-excision repair | 0.0335935694889657 |
GO:0051179 | localization | 0.0343797278606345 |
GO:0006944 | membrane fusion | 0.0343797278606345 |
GO:0051050 | positive regulation of transport | 0.0347541396382348 |
GO:0016197 | endosome transport | 0.0357691233612271 |
GO:0032944 | regulation of mononuclear cell proliferation | 0.0357691233612271 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 0.0357691233612271 |
GO:0050670 | regulation of lymphocyte proliferation | 0.0357691233612271 |
GO:0044459 | plasma membrane part | 0.0357691233612271 |
GO:0006289 | nucleotide-excision repair | 0.035940294858417 |
GO:0018212 | peptidyl-tyrosine modification | 0.036254941554881 |
GO:0001932 | regulation of protein amino acid phosphorylation | 0.0363598696327606 |
GO:0033238 | regulation of amine metabolic process | 0.0363598696327606 |
GO:0006521 | regulation of amino acid metabolic process | 0.0363598696327606 |
GO:0003684 | damaged DNA binding | 0.03774397245156 |
GO:0009897 | external side of plasma membrane | 0.03774397245156 |
GO:0004536 | deoxyribonuclease activity | 0.03774397245156 |
GO:0016064 | immunoglobulin mediated immune response | 0.03774397245156 |
GO:0051251 | positive regulation of lymphocyte activation | 0.03774397245156 |
GO:0019724 | B cell mediated immunity | 0.037782428412284 |
GO:0032943 | mononuclear cell proliferation | 0.037782428412284 |
GO:0046651 | lymphocyte proliferation | 0.037782428412284 |
GO:0000187 | activation of MAPK activity | 0.0401301956548925 |
GO:0008154 | actin polymerization and/or depolymerization | 0.0419210442296136 |
GO:0042113 | B cell activation | 0.0419210442296136 |
GO:0044237 | cellular metabolic process | 0.0424084858387849 |
GO:0042325 | regulation of phosphorylation | 0.0424720760935587 |
GO:0048471 | perinuclear region of cytoplasm | 0.0424720760935587 |
GO:0044238 | primary metabolic process | 0.042725642634001 |
GO:0043406 | positive regulation of MAP kinase activity | 0.0428184511525644 |
GO:0051174 | regulation of phosphorus metabolic process | 0.043780004563187 |
GO:0019220 | regulation of phosphate metabolic process | 0.043780004563187 |
GO:0044424 | intracellular part | 0.044082719341471 |
GO:0002253 | activation of immune response | 0.044082719341471 |
GO:0002449 | lymphocyte mediated immunity | 0.0442291349268762 |
GO:0006959 | humoral immune response | 0.0447841817368642 |
GO:0002250 | adaptive immune response | 0.0447841817368642 |
GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0447841817368642 |
GO:0051249 | regulation of lymphocyte activation | 0.0447841817368642 |
GO:0002443 | leukocyte mediated immunity | 0.0454950552453424 |
GO:0050865 | regulation of cell activation | 0.0461914459110638 |
GO:0007565 | female pregnancy | 0.0463062344559114 |
GO:0004177 | aminopeptidase activity | 0.0468465567744402 |
GO:0050778 | positive regulation of immune response | 0.0468465567744402 |
GO:0051247 | positive regulation of protein metabolic process | 0.0468465567744402 |
GO:0044260 | cellular macromolecule metabolic process | 0.0468465567744402 |
GO:0002684 | positive regulation of immune system process | 0.0468465567744402 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
---|---|---|
lymphocyte of B lineage | 9.30e-109 | 24 |
pro-B cell | 9.30e-109 | 24 |
B cell | 7.86e-63 | 14 |
lymphocyte | 9.83e-53 | 53 |
common lymphoid progenitor | 9.83e-53 | 53 |
nucleate cell | 1.09e-50 | 55 |
lymphoid lineage restricted progenitor cell | 2.12e-48 | 52 |
nongranular leukocyte | 3.91e-22 | 115 |
hematopoietic lineage restricted progenitor cell | 8.25e-19 | 120 |
leukocyte | 3.55e-18 | 136 |
mature B cell | 1.33e-15 | 2 |
pre-B-II cell | 1.33e-15 | 2 |
transitional stage B cell | 1.33e-15 | 2 |
small pre-B-II cell | 1.33e-15 | 2 |
immature B cell | 1.33e-15 | 2 |
hematopoietic oligopotent progenitor cell | 8.48e-15 | 161 |
hematopoietic multipotent progenitor cell | 8.48e-15 | 161 |
hematopoietic stem cell | 4.96e-14 | 168 |
angioblastic mesenchymal cell | 4.96e-14 | 168 |
hematopoietic cell | 3.93e-13 | 177 |
precursor B cell | 1.03e-10 | 3 |
B-1 B cell | 1.13e-08 | 1 |
antibody secreting cell | 1.22e-08 | 1 |
plasma cell | 1.22e-08 | 1 |
plasmablast | 1.22e-08 | 1 |
Ontology term | p-value | n |
---|---|---|
hemopoietic organ | 1.86e-16 | 7 |
immune organ | 1.86e-16 | 7 |
spleen | 1.69e-10 | 3 |
gastrointestinal system mesentery | 1.69e-10 | 3 |
stomach region | 1.69e-10 | 3 |
mesentery | 1.69e-10 | 3 |
gastrointestinal system serosa | 1.69e-10 | 3 |
mesentery of stomach | 1.69e-10 | 3 |
gut mesentery | 1.69e-10 | 3 |
dorsal mesentery | 1.69e-10 | 3 |
dorsal mesogastrium | 1.69e-10 | 3 |
peritoneal cavity | 1.69e-10 | 3 |
spleen primordium | 1.69e-10 | 3 |
vermiform appendix | 3.87e-09 | 1 |
caecum | 3.87e-09 | 1 |
midgut | 3.87e-09 | 1 |
tonsil | 5.70e-09 | 1 |
mucosa-associated lymphoid tissue | 5.70e-09 | 1 |
lymphoid tissue | 5.70e-09 | 1 |
tonsillar ring | 5.70e-09 | 1 |
thymus | 5.35e-08 | 4 |
hemolymphoid system gland | 5.35e-08 | 4 |
thymic region | 5.35e-08 | 4 |
pharyngeal gland | 5.35e-08 | 4 |
thymus primordium | 5.35e-08 | 4 |
chordate pharynx | 4.61e-07 | 10 |
pharyngeal region of foregut | 4.61e-07 | 10 |
Ontology term | p-value | n |
---|---|---|
lymphoma | 1.52e-12 | 10 |
acute leukemia | 9.74e-09 | 1 |
lymphatic system cancer | 1.13e-08 | 1 |
lymphosarcoma | 1.13e-08 | 1 |
genetic disease | 1.32e-08 | 1 |
monogenic disease | 1.32e-08 | 1 |
xeroderma pigmentosum | 1.32e-08 | 1 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.0972587 |
MA0004.1 | 0.711841 |
MA0006.1 | 0.137644 |
MA0007.1 | 0.241375 |
MA0009.1 | 0.669377 |
MA0014.1 | 0.00275422 |
MA0017.1 | 0.16476 |
MA0019.1 | 0.38027 |
MA0024.1 | 0.570967 |
MA0025.1 | 0.796882 |
MA0027.1 | 2.25966 |
MA0028.1 | 0.148561 |
MA0029.1 | 0.588958 |
MA0030.1 | 0.578277 |
MA0031.1 | 0.518602 |
MA0038.1 | 0.34128 |
MA0040.1 | 0.594421 |
MA0041.1 | 0.27117 |
MA0042.1 | 1.97132 |
MA0043.1 | 0.669676 |
MA0046.1 | 0.659066 |
MA0048.1 | 1.0552 |
MA0050.1 | 0.688784 |
MA0051.1 | 0.337676 |
MA0052.1 | 0.598036 |
MA0055.1 | 0.229721 |
MA0056.1 | 0 |
MA0057.1 | 0.0196406 |
MA0058.1 | 1.03067 |
MA0059.1 | 0.536577 |
MA0060.1 | 0.877206 |
MA0061.1 | 1.17249 |
MA0063.1 | 0 |
MA0066.1 | 0.905108 |
MA0067.1 | 0.975379 |
MA0068.1 | 0.341559 |
MA0069.1 | 0.655419 |
MA0070.1 | 0.644843 |
MA0071.1 | 0.831024 |
MA0072.1 | 0.640598 |
MA0073.1 | 0.000193423 |
MA0074.1 | 0.894848 |
MA0076.1 | 0.194691 |
MA0077.1 | 0.633326 |
MA0078.1 | 0.424186 |
MA0081.1 | 0.18212 |
MA0083.1 | 0.676499 |
MA0084.1 | 1.15904 |
MA0087.1 | 0.63829 |
MA0088.1 | 0.426561 |
MA0089.1 | 0 |
MA0090.1 | 0.205547 |
MA0091.1 | 0.258318 |
MA0092.1 | 0.647316 |
MA0093.1 | 0.851459 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.353174 |
MA0101.1 | 0.437519 |
MA0103.1 | 0.815939 |
MA0105.1 | 1.29048 |
MA0106.1 | 0.37688 |
MA0107.1 | 1.08326 |
MA0108.2 | 0.515791 |
MA0109.1 | 0 |
MA0111.1 | 0.215855 |
MA0113.1 | 0.39123 |
MA0114.1 | 0.30732 |
MA0115.1 | 0.900969 |
MA0116.1 | 0.660297 |
MA0117.1 | 0.705104 |
MA0119.1 | 0.170362 |
MA0122.1 | 0.729811 |
MA0124.1 | 0.860724 |
MA0125.1 | 0.779672 |
MA0130.1 | 0 |
MA0131.1 | 1.12143 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.698212 |
MA0136.1 | 0.917713 |
MA0139.1 | 0.181369 |
MA0140.1 | 0.826015 |
MA0141.1 | 0.180729 |
MA0142.1 | 0.489543 |
MA0143.1 | 0.391385 |
MA0144.1 | 0.284854 |
MA0145.1 | 0.478485 |
MA0146.1 | 0.197185 |
MA0147.1 | 0.0991954 |
MA0148.1 | 0.276339 |
MA0149.1 | 5.05306 |
MA0062.2 | 0.0512998 |
MA0035.2 | 0.824687 |
MA0039.2 | 0.0386601 |
MA0138.2 | 1.08869 |
MA0002.2 | 0.82964 |
MA0137.2 | 0.153033 |
MA0104.2 | 0.236755 |
MA0047.2 | 0.366327 |
MA0112.2 | 1.33111 |
MA0065.2 | 0.140846 |
MA0150.1 | 0.201098 |
MA0151.1 | 0 |
MA0152.1 | 0.838393 |
MA0153.1 | 0.763487 |
MA0154.1 | 0.912675 |
MA0155.1 | 0.6552 |
MA0156.1 | 0.469333 |
MA0157.1 | 0.46471 |
MA0158.1 | 0 |
MA0159.1 | 0.327637 |
MA0160.1 | 0.288813 |
MA0161.1 | 0 |
MA0162.1 | 0.000900738 |
MA0163.1 | 0.0365728 |
MA0164.1 | 0.402162 |
MA0080.2 | 0.851709 |
MA0018.2 | 0.378086 |
MA0099.2 | 0.312108 |
MA0079.2 | 9.91681e-05 |
MA0102.2 | 1.1957 |
MA0258.1 | 0.964206 |
MA0259.1 | 1.1468 |
MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
TF | #promoters | Enrichment | p-value | q-value |
---|---|---|---|---|
EBF1#1879 | 7 | 4.15635119506554 | 0.000635940891991327 | 0.00521531455191851 |
TCF12#6938 | 5 | 3.54482163406214 | 0.00985505923893219 | 0.0370314647713477 |
ZEB1#6935 | 4 | 4.50358187134503 | 0.00989309630417724 | 0.0371169696774784 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
This analysis result is provided for C0 - C305 clusters.