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MCL coexpression mm9:397: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0165945545155982;27416,18671!GO:0043492;ATPase activity, coupled to movement of substances;0.0165945545155982;27416,18671!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0165945545155982;27416,18671!GO:0015399;primary active transmembrane transporter activity;0.0165945545155982;27416,18671!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0165945545155982;27416,18671!GO:0042910;xenobiotic transporter activity;0.0165945545155982;18671!GO:0008559;xenobiotic-transporting ATPase activity;0.0165945545155982;18671!GO:0015239;multidrug transporter activity;0.0193571315492903;18671!GO:0046581;intercellular canaliculus;0.0300962493678044;18671!GO:0042623;ATPase activity, coupled;0.0308035786832829;27416,18671!GO:0016887;ATPase activity;0.0354472679943566;27416,18671!GO:0042176;regulation of protein catabolic process;0.0354472679943566;66222!GO:0015893;drug transport;0.0358958214104973;18671!GO:0009894;regulation of catabolic process;0.0358958214104973;66222!GO:0015238;drug transporter activity;0.0360739735558713;18671!GO:0022804;active transmembrane transporter activity;0.0371635418739551;27416,18671!GO:0048029;monosaccharide binding;0.0476900747764418;83382!}}
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activity, coupled to transmembrane movement of substances;0.0165945545155982;27416,18671!GO:0043492;ATPase activity, coupled to movement of substances;0.0165945545155982;27416,18671!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0165945545155982;27416,18671!GO:0015399;primary active transmembrane transporter activity;0.0165945545155982;27416,18671!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0165945545155982;27416,18671!GO:0042910;xenobiotic transporter activity;0.0165945545155982;18671!GO:0008559;xenobiotic-transporting ATPase activity;0.0165945545155982;18671!GO:0015239;multidrug transporter activity;0.0193571315492903;18671!GO:0046581;intercellular canaliculus;0.0300962493678044;18671!GO:0042623;ATPase activity, coupled;0.0308035786832829;27416,18671!GO:0016887;ATPase activity;0.0354472679943566;27416,18671!GO:0042176;regulation of protein catabolic process;0.0354472679943566;66222!GO:0015893;drug transport;0.0358958214104973;18671!GO:0009894;regulation of catabolic process;0.0358958214104973;66222!GO:0015238;drug transporter activity;0.0360739735558713;18671!GO:0022804;active transmembrane transporter activity;0.0371635418739551;27416,18671!GO:0048029;monosaccharide binding;0.0476900747764418;83382!|ontology_enrichment_celltype=CL:0000627!2.44e-21!3;CL:0000682!2.44e-21!3;CL:0000239!2.00e-18!6;CL:0000677!2.00e-18!6;CL:0000212!2.00e-18!6;CL:0000584!2.00e-18!6;CL:0000075!7.62e-16!7;CL:0000066!5.90e-13!25;CL:0002563!2.16e-12!9;CL:0002251!2.16e-12!9;CL:0000473!1.71e-09!7;CL:0002076!1.57e-07!15|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0000344!1.82e-28!15;UBERON:0002465!1.78e-21!3;UBERON:0001242!2.15e-18!13;UBERON:0000060!2.15e-18!13;UBERON:0001262!2.15e-18!13;UBERON:0004786!2.15e-18!13;UBERON:0004923!1.41e-17!24;UBERON:0001962!2.51e-15!2;UBERON:0001961!2.51e-15!2;UBERON:0001744!2.51e-15!2;UBERON:0003350!2.16e-12!9;UBERON:0004808!2.16e-12!9;UBERON:0001277!2.16e-12!9;UBERON:0000485!3.45e-10!11;UBERON:0000331!9.30e-10!3;UBERON:0002116!9.30e-10!3;UBERON:0001204!9.30e-10!3;UBERON:0001168!9.30e-10!3;UBERON:0003199!1.56e-08!1;UBERON:0000029!7.68e-08!1;UBERON:0001097!7.68e-08!1;UBERON:0003968!7.68e-08!1;UBERON:0001467!7.68e-08!1;UBERON:0000160!1.46e-07!31;UBERON:0002108!1.54e-07!4|tfbs_overrepresentation_for_novel_motifs=0.149902,0.327473,0.133309,0.526976,0.906347,0.188081,0.254787,0.308279,0.32877,0.0966197,0.221763,0.687282,0.130811,0.264234,0.271754,0,0.42315,0.511529,0.114994,0.11724,0.111207,0.153134,0.728683,0.527336,0.138033,0.285776,0.260094,0.202945,0.313062,0.353285,0.192916,0.512187,0.0660956,0.424507,0.0793793,0.0928537,0.0618293,0.242872,0.430935,0.364515,0.891393,0.571717,0.617892,0.274585,0.0590634,0.170437,0.355451,0.214351,0.499056,0.095769,0.408111,0.307229,0.063174,0.641205,0.657376,0.269785,0.100694,0.23598,0.740917,0.268198,0.494318,0.845221,0.154301,0.398468,0.278491,0.433342,0.785371,1.12243,0.490165,0.979213,0.12178,0.58423,0.0244677,0.6886,0.0208952,0.208208,1.02246,0.914794,0.479091,0.736885,0.138314,0.438213,0.31368,1.68368,0.582029,0.000483541,1.19933,0.590279,0.359539,1.2816,0.851763,0.586575,0.523661,0.545909,0.0506699,0.0436985,0.87978,0.526183,0.355664,0.291825,0.834613,0.511936,0.625103,0.408622,0.407717,0.196264,0.459578,0.211422,0.116526,0.112248,0.145352,0.626748,0.366686,0.640523,0.858505,0.88475,0.0705519,0.180644,0.424276,0.820725,0.693645,0.991308,0.287218,0.345253,0.910454,0.482363,0.261058,0.517583,0.783932,0.260855,2.51834,0.990708,0.75595,0.767443,0.879201,0.452982,0.15539,0.197578,0.832159,1.64606,1.25025,0.789841,0.296788,0.521565,0.402166,0.196898,0.941495,1.60668,0.92438,0.0717633,0.0705641,0.0028093,0.642658,0.698566,0.27974,0.718834,0.30804,0.603495,0.453591,0.155206,0.841238,1.42171,0.482758,0.442531,1.03222,0.273933,0.220881,0.684489,0.000971366|tfbs_overrepresentation_jaspar=MA0003.1;0.0394173,MA0004.1;0.178381,MA0006.1;0.265566,MA0007.1;0.168178,MA0009.1;0.535932,MA0014.1;0.00432862,MA0017.1;0.30345,MA0019.1;0.376509,MA0024.1;0.496718,MA0025.1;0.751694,MA0027.1;2.14278,MA0028.1;0.0821841,MA0029.1;0.477444,MA0030.1;1.21364,MA0031.1;0.451927,MA0038.1;0.285714,MA0040.1;0.547233,MA0041.1;1.89679,MA0042.1;0.384176,MA0043.1;0.624178,MA0046.1;1.39477,MA0048.1;0.145518,MA0050.1;0.205672,MA0051.1;0.2928,MA0052.1;0.554531,MA0055.1;0.106374,MA0056.1;0,MA0057.1;0.00889471,MA0058.1;0.117003,MA0059.1;0.124358,MA0060.1;0.0417645,MA0061.1;3.39719,MA0063.1;0,MA0066.1;1.3903,MA0067.1;0.857286,MA0068.1;0.4712,MA0069.1;0.554839,MA0070.1;0.54606,MA0071.1;0.20507,MA0072.1;0.538403,MA0073.1;0.00268899,MA0074.1;0.695974,MA0076.1;0.101055,MA0077.1;0.518913,MA0078.1;0.855296,MA0081.1;0.429201,MA0083.1;0.623446,MA0084.1;1.1752,MA0087.1;1.42725,MA0088.1;0.978382,MA0089.1;0,MA0090.1;0.471234,MA0091.1;1.04884,MA0092.1;1.47114,MA0093.1;0.0864726,MA0095.1;0,MA0098.1;0,MA0100.1;0.2406,MA0101.1;1.90338,MA0103.1;0.657254,MA0105.1;1.37354,MA0106.1;0.325663,MA0107.1;4.25171,MA0108.2;1.02466,MA0109.1;0,MA0111.1;0.164756,MA0113.1;0.818211,MA0114.1;0.43311,MA0115.1;0.626759,MA0116.1;0.561344,MA0117.1;0.597086,MA0119.1;0.130171,MA0122.1;0.615314,MA0124.1;0.80652,MA0125.1;1.7455,MA0130.1;0,MA0131.1;0.372683,MA0132.1;0,MA0133.1;0,MA0135.1;0.657882,MA0136.1;0.731186,MA0139.1;0.550862,MA0140.1;0.240513,MA0141.1;1.16831,MA0142.1;0.439269,MA0143.1;0.31603,MA0144.1;2.18311,MA0145.1;1.05479,MA0146.1;0.00163181,MA0147.1;0.215066,MA0148.1;1.66813,MA0149.1;0.415447,MA0062.2;0.0201154,MA0035.2;0.244063,MA0039.2;0.00524431,MA0138.2;0.366012,MA0002.2;0.886864,MA0137.2;1.15722,MA0104.2;0.145321,MA0047.2;1.41968,MA0112.2;0.326529,MA0065.2;1.05819,MA0150.1;0.970484,MA0151.1;0,MA0152.1;0.778204,MA0153.1;1.61457,MA0154.1;1.0685,MA0155.1;0.100954,MA0156.1;0.100572,MA0157.1;0.411541,MA0158.1;0,MA0159.1;0.851047,MA0160.1;0.191754,MA0161.1;0,MA0162.1;0.00257384,MA0163.1;0.00199685,MA0164.1;0.264905,MA0080.2;0.0935932,MA0018.2;0.272436,MA0099.2;0.360735,MA0079.2;1.07076e-06,MA0102.2;1.22663,MA0258.1;0.401444,MA0259.1;0.0546944,MA0442.1;0}}

Latest revision as of 15:14, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:115993887..115993898,-p@chr11:115993887..115993898
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Mm9::chr11:115994191..115994226,-p@chr11:115994191..115994226
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Mm9::chr11:70323682..70323701,+p4@Tm4sf5
Mm9::chr13:32943045..32943055,-p1@Serpinb1a
Mm9::chr16:20364230..20364242,-p7@Abcc5
Mm9::chr18:65200347..65200364,-p@chr18:65200347..65200364
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Mm9::chr18:65200384..65200395,-p@chr18:65200384..65200395
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Mm9::chr19:5953618..5953632,+p@chr19:5953618..5953632
+
Mm9::chr3:158560571..158560574,+p@chr3:158560571..158560574
+
Mm9::chr4:117118403..117118419,+p1@ENSMUST00000136115
Mm9::chr4:117118428..117118440,+p2@ENSMUST00000136115
Mm9::chr5:8660633..8660652,+p@chr5:8660633..8660652
+
Mm9::chr6:82702729..82702733,-p@chr6:82702729..82702733
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Mm9::chr6:86535959..86535964,-p@chr6:86535959..86535964
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Mm9::chr7:121860793..121860804,+p@chr7:121860793..121860804
+
Mm9::chr7:19117743..19117762,-p2@Psg25
Mm9::chr7:50606748..50606782,+p1@Siglec5
Mm9::chr7:52393029..52393077,-p@chr7:52393029..52393077
-
Mm9::chr8:8533654..8533663,+p@chr8:8533654..8533663
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0042626ATPase activity, coupled to transmembrane movement of substances0.0165945545155982
GO:0043492ATPase activity, coupled to movement of substances0.0165945545155982
GO:0016820hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances0.0165945545155982
GO:0015399primary active transmembrane transporter activity0.0165945545155982
GO:0015405P-P-bond-hydrolysis-driven transmembrane transporter activity0.0165945545155982
GO:0042910xenobiotic transporter activity0.0165945545155982
GO:0008559xenobiotic-transporting ATPase activity0.0165945545155982
GO:0015239multidrug transporter activity0.0193571315492903
GO:0046581intercellular canaliculus0.0300962493678044
GO:0042623ATPase activity, coupled0.0308035786832829
GO:0016887ATPase activity0.0354472679943566
GO:0042176regulation of protein catabolic process0.0354472679943566
GO:0015893drug transport0.0358958214104973
GO:0009894regulation of catabolic process0.0358958214104973
GO:0015238drug transporter activity0.0360739735558713
GO:0022804active transmembrane transporter activity0.0371635418739551
GO:0048029monosaccharide binding0.0476900747764418



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0394173
MA0004.10.178381
MA0006.10.265566
MA0007.10.168178
MA0009.10.535932
MA0014.10.00432862
MA0017.10.30345
MA0019.10.376509
MA0024.10.496718
MA0025.10.751694
MA0027.12.14278
MA0028.10.0821841
MA0029.10.477444
MA0030.11.21364
MA0031.10.451927
MA0038.10.285714
MA0040.10.547233
MA0041.11.89679
MA0042.10.384176
MA0043.10.624178
MA0046.11.39477
MA0048.10.145518
MA0050.10.205672
MA0051.10.2928
MA0052.10.554531
MA0055.10.106374
MA0056.10
MA0057.10.00889471
MA0058.10.117003
MA0059.10.124358
MA0060.10.0417645
MA0061.13.39719
MA0063.10
MA0066.11.3903
MA0067.10.857286
MA0068.10.4712
MA0069.10.554839
MA0070.10.54606
MA0071.10.20507
MA0072.10.538403
MA0073.10.00268899
MA0074.10.695974
MA0076.10.101055
MA0077.10.518913
MA0078.10.855296
MA0081.10.429201
MA0083.10.623446
MA0084.11.1752
MA0087.11.42725
MA0088.10.978382
MA0089.10
MA0090.10.471234
MA0091.11.04884
MA0092.11.47114
MA0093.10.0864726
MA0095.10
MA0098.10
MA0100.10.2406
MA0101.11.90338
MA0103.10.657254
MA0105.11.37354
MA0106.10.325663
MA0107.14.25171
MA0108.21.02466
MA0109.10
MA0111.10.164756
MA0113.10.818211
MA0114.10.43311
MA0115.10.626759
MA0116.10.561344
MA0117.10.597086
MA0119.10.130171
MA0122.10.615314
MA0124.10.80652
MA0125.11.7455
MA0130.10
MA0131.10.372683
MA0132.10
MA0133.10
MA0135.10.657882
MA0136.10.731186
MA0139.10.550862
MA0140.10.240513
MA0141.11.16831
MA0142.10.439269
MA0143.10.31603
MA0144.12.18311
MA0145.11.05479
MA0146.10.00163181
MA0147.10.215066
MA0148.11.66813
MA0149.10.415447
MA0062.20.0201154
MA0035.20.244063
MA0039.20.00524431
MA0138.20.366012
MA0002.20.886864
MA0137.21.15722
MA0104.20.145321
MA0047.21.41968
MA0112.20.326529
MA0065.21.05819
MA0150.10.970484
MA0151.10
MA0152.10.778204
MA0153.11.61457
MA0154.11.0685
MA0155.10.100954
MA0156.10.100572
MA0157.10.411541
MA0158.10
MA0159.10.851047
MA0160.10.191754
MA0161.10
MA0162.10.00257384
MA0163.10.00199685
MA0164.10.264905
MA0080.20.0935932
MA0018.20.272436
MA0099.20.360735
MA0079.21.07076e-06
MA0102.21.22663
MA0258.10.401444
MA0259.10.0546944
MA0442.10
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