MCL coexpression mm9:600: Difference between revisions
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{{MCL_coexpression_mm9| | {{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=-0.0340769738076358,-0.0178866900176871,-0.0119883852945622,-0.039945288714244,-0.0495091052751821,-0.0157684268538527,-0.0139048761596431,-0.0495091052751821,-0.0447420036843848,-0.0495091052751821,-0.0495091052751821,-0.0495091052751821,-0.0437898274100862,-0.0410800023283993,-0.0286981205093568,-0.0115529075269781,-0.0303143568482738,-0.0354874619650084,-0.0495091052751821,-0.0495091052751821,0.046750852760748,0.136204184066776,0.129011666263079,0.0393314409033491,0.0458821306271693,-0.00052234681619775,0.00502447132149767,-0.000867067995692333,-0.043212812915399,-0.0495091052751821,0.0179936533954424,0.154138703258272,0.137474720732862,0.0766991522581089,-0.0403255284691286,-0.0495091052751821,-0.0293372125069707,-0.0368558532555369,-0.0495091052751821,-0.0495091052751821,-0.0495091052751821,-0.0118264630899133,-0.0495091052751821,1.18371326746404,1.17904675674118,1.15764274852389,0.900425763929893,0.300031812032066,0.47515571709645,0.547014298404373,0.472259224195005,0.448544344022596,-0.0438956050906864,-0.0297690832340494,-0.0495091052751821,0.398320274757804,0.290467385019869,0.661306506711253,-0.0238757361683636,-0.0341420283440996,-0.0495091052751821,0.904434020123647,0.714662805023258,0.651418198129469,0.713029715414017,0.623821613015433,0.749162457519151,0.733005594277654,-0.0308218638947536,-0.0362752789346345,-0.0240945932688989,0.056525130580051,0.0419360107631841,-0.0369634078043488,-0.0264424991837259,-0.0495091052751821,0.0451374938496502,0.0134691479696978,0.0145287441731235,-0.0275859950463687,-0.00698317401210465,-0.0495091052751821,0.0555168148453519,0.00931728802288883,0.0222833377239713,0.0402395912998132,0.052485881468798,-0.0256700394261767,0.172522244928043,0.187579906544866,0.0596301681246152,-0.0270414465517676,-0.0307339493436001,-0.0495091052751821,-0.031390347663827,-0.0495091052751821,0.082846032418262,0.28411958194847,0.210319753193283,0.207393220970978,-0.0153735514529405,0.190947764976522,0.0421558988578215,-0.0495091052751821,0.252011084762254,0.258055467051194,0.220519723110664,-0.00153904317654044,0.0863300230861932,0.114112280283364,0.0278439734804751,0.0611197624643467,0.0739820042752433,0.0224620862011353,0.0917781683744033,0.0633913114331435,0.132267727623859,0.16530540660271,0.0332243005141884,0.0822994921807187,0.0319203200316744,0.0714589894226959,-0.0114290619219682,-0.0328271788043804,0.0339728009664256,0.0139967749943844,-0.0495091052751821,-0.0325013069641117,-0.0451798571485879,0.00824749368603785,0.00527219504724983,0.016271531517666,-0.0343204187304576,0.00348617015665966,0.00500086620099963,0.01272504523492,0.0751266630683921,0.0843159291019371,0.0259777573614933,0.0368995399025925,0.0329148522555913,-0.0305248363797024,0.0284587176429397,-0.00432049252404514,0.0528578760169341,0.0487533499751703,0.0110129974260979,0.0583971286791512,-0.00188928044546324,-0.00375827671648874,-0.00546141020025437,0.0323937199790058,0.0696262679052613,0.0322083359514367,0.0883951512120725,0.0348007034894431,-0.0495091052751821,-0.0495091052751821,-0.0495091052751821,0.0799247874914408,0.051082546403328,0.0653445303986364,0.0846170733881766,0.069235148269351,0.0585928145013965,0.070826788303315,0.0958156111450472,0.0495900745295462,0.0281699140607339,0.144220857188948,0.0732609885502551,0.0474744734422382,0.0450940470484765,0.0638865307501141,-0.0136032439794954,0.0401806861408047,-0.0495091052751821,-0.0495091052751821,-0.000331244667853951,-0.0192777287989508,0.0200801696213074,0.0201793359714939,0.00480217021192716,0.00824015899332403,0.0106470088445529,0.0112645902783566,0.0375675357898815,0.0291984471634642,0.0261816541693772,0.0805514192175313,0.025416644672964,0.00559568649402129,0.0305388570232263,-0.00924642312529926,0.00512144213224044,0.00168800268962947,0.0100615568673975,0.0485909619142199,0.0139332568522579,0.0278188038384359,0.0101104956805422,0.00992196158668325,-0.0170865318033445,-0.0292374860657539,-0.0430145956150955,-0.0161689431181557,-0.0213225055374211,-0.0171220100161055,0.0130476497341789,-0.0147578138151567,0.0337953670105597,-0.0119228137549849,-0.000483062340307913,0.0284841494508956,0.00735684430472442,-0.0250578342793728,-0.00689296841510286,-0.0108161265089691,0.0527083575920759,-0.0253189820945327,-0.0248937192473591,-0.0177742224403191,-0.0355812493537866,-0.017385012963816,0.00193244414763402,0.0505658911092316,0.0706963687132415,0.0898491816394677,0.0499256681202704,0.0660459698431434,0.119911152512162,0.0948187523762678,0.136049172682995,0.095409731065905,0.0225546646217825,0.0549469506702038,0.0298231596810095,0.0388441153813597,0.217733679854293,0.124265158189497,0.410904310801136,0.341319654197517,0.315965864586781,0.456510760489604,0.508840756818262,0.464420297949805,0.490921780649813,0.527774012800027,0.443410643025593,-0.00951336686607083,0.104203392090207,0.0454773908500761,0.0675053882070424,0.123980548022307,0.0171588926097092,0.0393371065391433,0.0229685224669982,0.083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regulation of cyclin-dependent protein kinase activity;6.23135703143626e-06;12575,12578!GO:0004861;cyclin-dependent protein kinase inhibitor activity;1.45398330733513e-05;12575,12578!GO:0000079;regulation of cyclin-dependent protein kinase activity;1.90402575960552e-05;12575,12578!GO:0004860;protein kinase inhibitor activity;3.9984540951716e-05;12575,12578!GO:0030888;regulation of B cell proliferation;3.9984540951716e-05;12575,12578!GO:0019210;kinase inhibitor activity;3.9984540951716e-05;12575,12578!GO:0042100;B cell proliferation;5.20763409055744e-05;12575,12578!GO:0006469;negative regulation of protein kinase activity;6.63733938348437e-05;12575,12578!GO:0033673;negative regulation of kinase activity;6.63733938348437e-05;12575,12578!GO:0050864;regulation of B cell activation;6.63733938348437e-05;12575,12578!GO:0051348;negative regulation of transferase activity;6.63733938348437e-05;12575,12578!GO:0007050;cell cycle arrest;8.56811591822485e-05;12575,12578!GO:0043086;negative regulation of catalytic activity;8.63602173202896e-05;12575,12578!GO:0050670;regulation of lymphocyte proliferation;9.5408999881324e-05;12575,12578!GO:0032944;regulation of mononuclear cell proliferation;9.5408999881324e-05;12575,12578!GO:0019887;protein kinase regulator activity;0.000126769169608281;12575,12578!GO:0032943;mononuclear cell proliferation;0.000147639432823766;12575,12578!GO:0019207;kinase regulator activity;0.000147639432823766;12575,12578!GO:0046651;lymphocyte proliferation;0.000147639432823766;12575,12578!GO:0051249;regulation of lymphocyte activation;0.000172542499620451;12575,12578!GO:0042113;B cell activation;0.000172542499620451;12575,12578!GO:0050865;regulation of cell activation;0.000172542499620451;12575,12578!GO:0045786;negative regulation of progression through cell cycle;0.000298715677694475;12575,12578!GO:0008285;negative regulation of cell proliferation;0.000298715677694475;12575,12578!GO:0045859;regulation of protein kinase activity;0.00033238058405681;12575,12578!GO:0043549;regulation of kinase activity;0.000345360980088448;12575,12578!GO:0051338;regulation of transferase activity;0.000347917434255191;12575,12578!GO:0000074;regulation of progression through cell cycle;0.000584300995929853;12575,12578!GO:0046649;lymphocyte activation;0.00059236837780091;12575,12578!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0016244;non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0043070;regulation of non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0045321;leukocyte activation;0.000644975998621454;12575,12578!GO:0004857;enzyme inhibitor activity;0.000644975998621454;12575,12578!GO:0001775;cell activation;0.000721353759210549;12575,12578!GO:0050790;regulation of catalytic activity;0.000997645726835604;12575,12578!GO:0033087;negative regulation of immature T cell proliferation;0.000997645726835604;12578!GO:0033088;negative regulation of immature T cell proliferation in the thymus;0.000997645726835604;12578!GO:0051239;regulation of multicellular organismal process;0.0010253245289803;12575,12578!GO:0065009;regulation of a molecular function;0.001243545187586;12575,12578!GO:0042127;regulation of cell proliferation;0.00126871442388828;12575,12578!GO:0030332;cyclin binding;0.00135391068072313;12575!GO:0051726;regulation of cell cycle;0.00147511678563941;12575,12578!GO:0033080;immature T cell proliferation in the thymus;0.001613125978755;12578!GO:0033079;immature T cell proliferation;0.001613125978755;12578!GO:0033083;regulation of immature T cell proliferation;0.001613125978755;12578!GO:0033084;regulation of immature T cell proliferation in the thymus;0.001613125978755;12578!GO:0008283;cell proliferation;0.00230410917234263;12575,12578!GO:0048103;somatic stem cell division;0.00232079898255502;12578!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00265337413755587;12575!GO:0030889;negative regulation of B cell proliferation;0.00297288676570365;12578!GO:0022402;cell cycle process;0.00303730721766891;12575,12578!GO:0017145;stem cell division;0.00321820197480138;12578!GO:0006915;apoptosis;0.00347919357513534;12575,12578!GO:0012501;programmed cell death;0.00353046029921064;12575,12578!GO:0050869;negative regulation of B cell activation;0.00363859322660616;12578!GO:0008219;cell death;0.00363859322660616;12575,12578!GO:0016265;death;0.00363859322660616;12575,12578!GO:0007569;cell aging;0.00410573729206283;12578!GO:0030890;positive regulation of B cell proliferation;0.00410573729206283;12575!GO:0007049;cell cycle;0.00412965310414495;12575,12578!GO:0002376;immune system process;0.00431174729559889;12575,12578!GO:0048523;negative regulation of cellular process;0.00550853610086116;12575,12578!GO:0050672;negative regulation of lymphocyte proliferation;0.00553819046196241;12578!GO:0032945;negative regulation of mononuclear cell proliferation;0.00553819046196241;12578!GO:0016301;kinase activity;0.00562450782962479;12575,12578!GO:0048519;negative regulation of biological process;0.00598149821554142;12575,12578!GO:0009411;response to UV;0.00676547334841651;12575!GO:0033077;T cell differentiation in the thymus;0.00676547334841651;12578!GO:0051250;negative regulation of lymphocyte activation;0.00676547334841651;12578!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.00684045775682157;12575,12578!GO:0050871;positive regulation of B cell activation;0.00684045775682157;12575!GO:0007568;aging;0.00726533549337855;12578!GO:0048468;cell development;0.00859156771462019;12575,12578!GO:0032946;positive regulation of mononuclear cell proliferation;0.00897044840445193;12575!GO:0050671;positive regulation of lymphocyte proliferation;0.00897044840445193;12575!GO:0042129;regulation of T cell proliferation;0.0103279077926027;12578!GO:0016072;rRNA metabolic process;0.0126990586550902;12578!GO:0006364;rRNA processing;0.0126990586550902;12578!GO:0042098;T cell proliferation;0.013012826050804;12578!GO:0051251;positive regulation of lymphocyte activation;0.014078079385034;12575!GO:0030217;T cell differentiation;0.014078079385034;12578!GO:0050863;regulation of T cell activation;0.0143636908787096;12578!GO:0009416;response to light stimulus;0.0164409904305137;12575!GO:0048869;cellular developmental process;0.0169711008751167;12575,12578!GO:0030154;cell differentiation;0.0169711008751167;12575,12578!GO:0016740;transferase activity;0.0177298342497547;12575,12578!GO:0030098;lymphocyte differentiation;0.0197578127502482;12578!GO:0009314;response to radiation;0.0197578127502482;12575!GO:0008544;epidermis development;0.0201668869473389;12578!GO:0007398;ectoderm development;0.0209812073796822;12578!GO:0005730;nucleolus;0.0219823875503924;12578!GO:0042110;T cell activation;0.0239743421323824;12578!GO:0042254;ribosome biogenesis and assembly;0.0249212517907133;12578!GO:0002521;leukocyte differentiation;0.0252534270819102;12578!GO:0043066;negative regulation of apoptosis;0.0293016798776038;12575!GO:0043069;negative regulation of programmed cell death;0.0293872403622387;12575!GO:0043068;positive regulation of programmed cell death;0.031771972700846;12575!GO:0009628;response to abiotic stimulus;0.0320202372355373;12575!GO:0008284;positive regulation of cell proliferation;0.0332022488739404;12575!GO:0022613;ribonucleoprotein complex biogenesis and assembly;0.0352890386214833;12578!GO:0030097;hemopoiesis;0.038435743270726;12578!GO:0032502;developmental process;0.0396246347091916;12575,12578!GO:0006974;response to DNA damage stimulus;0.0415787003990648;12575!GO:0048534;hemopoietic or lymphoid organ development;0.0415787003990648;12578!GO:0051301;cell division;0.0415787003990648;12578!GO:0002520;immune system development;0.0435798320167287;12578!GO:0009719;response to endogenous stimulus;0.0435798320167287;12575!GO:0050794;regulation of cellular process;0.046956514775283;12575,12578!GO:0009888;tissue development;0.048051995656815;12578!|ontology_enrichment_celltype=CL:0000333!8.91e-12!10;CL:0000095!8.91e-12!10;CL:0000243!8.91e-12!10;CL:0000123!8.91e-12!10;CL:0000125!8.91e-12!10;CL:0000030!8.91e-12!10;CL:0000339!8.91e-12!10;CL:0000107!9.73e-11!9;CL:0002453!3.26e-10!8;CL:0000055!4.60e-10!49;CL:0000222!5.40e-09!7;CL:0000680!2.29e-08!6;CL:0000183!2.29e-08!6;CL:0000187!2.29e-08!6;CL:0000056!2.29e-08!6;CL:0000128!7.39e-08!6;CL:0000126!7.39e-08!6;CL:0000127!7.39e-08!6|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0000010!2.56e-12!11;UBERON:0002410!9.73e-11!9|tfbs_overrepresentation_for_novel_motifs=0.737036,0.409645,0.245304,0.303186,0.1565,0.315748,0.396495,0.303924,0.320069,0.336879,0.357058,0.385627,0.630954,0.407615,0.169024,0,0.587245,0.459418,0.586013,1.35406,0.215242,1.06603,0.406794,0.155356,0.251585,0.432737,0.951622,0.334131,0.558665,0.198166,0.321757,0.683831,0.891038,0.504772,1.55237,1.83832,0.862318,0.382372,0.79515,1.70931,0.153518,0.326286,0.407596,0.508662,0.153213,0.293566,0.512146,0.34807,0.337012,0.564214,1.39948,0.457464,0.0502729,1.91948,0.837732,0.414119,0.200484,0.37415,0.250759,0.412262,0.664611,0.46618,0.340458,0.560059,0.424276,0.598412,0.970969,1.3158,0.660133,1.17005,0.650349,0.0945081,0.102623,0.870406,0.51601,0.835139,1.81769,0.50152,0.648171,0.218647,0.316038,0.60374,0.464847,0.293128,0.758319,0.206209,0.0395547,0.766772,0.516731,1.47691,1.03946,0.763136,0.696137,0.484945,0.391609,0.11194,0.299765,0.698838,0.512384,0.166936,0.142282,0.683562,0.803823,0.571268,0.57027,0.3259,0.627019,0.344504,1.18615,0.619563,0.723377,1.8882,0.626352,0.949483,1.04639,0.904538,0.278854,0.826326,0.58848,0.139554,0.875675,0.540309,0.434408,0.500675,1.09972,0.651709,0.403884,0.689622,0.969481,0.49047,0.787341,0.296885,0.940498,0.426575,1.06766,0.231689,0.753345,0.327523,1.01927,1.84381,1.44523,0.975592,0.445463,0.693891,0.564145,0.326684,0.515065,1.80426,0.276297,0.477267,1.66291,0.404179,0.822286,0.370892,0.425729,0.901933,0.458393,0.178202,0.265096,1.37924,1.02862,0.757491,0.652135,0.25933,0.561023,1.07498,0.436256,0.384198,0.556474|tfbs_overrepresentation_jaspar=MA0003.1;0.829197,MA0004.1;0.303605,MA0006.1;0.16569,MA0007.1;0.790701,MA0009.1;0.709264,MA0014.1;1.34901,MA0017.1;0.546298,MA0019.1;0.535691,MA0024.1;0.667197,MA0025.1;0.936082,MA0027.1;2.34178,MA0028.1;0.173587,MA0029.1;1.55834,MA0030.1;0.65267,MA0031.1;0.618697,MA0038.1;0.432665,MA0040.1;0.721328,MA0041.1;0.239557,MA0042.1;0.228771,MA0043.1;0.802848,MA0046.1;0.743934,MA0048.1;0.168666,MA0050.1;0.337476,MA0051.1;0.440863,MA0052.1;0.729105,MA0055.1;0.10681,MA0056.1;0,MA0057.1;0.630087,MA0058.1;0.223242,MA0059.1;0.233271,MA0060.1;0.351437,MA0061.1;0.40468,MA0063.1;0,MA0066.1;1.08293,MA0067.1;1.04514,MA0068.1;0.0405002,MA0069.1;0.729433,MA0070.1;0.720077,MA0071.1;0.336739,MA0072.1;0.711905,MA0073.1;1.47506,MA0074.1;0.390075,MA0076.1;0.200996,MA0077.1;0.691048,MA0078.1;0.471303,MA0081.1;0.702944,MA0083.1;0.802078,MA0084.1;1.3693,MA0087.1;0.760279,MA0088.1;1.08862,MA0089.1;0,MA0090.1;1.38006,MA0091.1;0.315003,MA0092.1;0.274547,MA0093.1;0.179936,MA0095.1;0,MA0098.1;0,MA0100.1;0.379666,MA0101.1;0.240622,MA0103.1;0.19444,MA0105.1;0.226879,MA0106.1;6.61172,MA0107.1;0.189625,MA0108.2;0.557195,MA0109.1;0,MA0111.1;0.78079,MA0113.1;0.452439,MA0114.1;0.400482,MA0115.1;0.805567,MA0116.1;0.165534,MA0117.1;0.774259,MA0119.1;0.676816,MA0122.1;0.793507,MA0124.1;0.992825,MA0125.1;0.920215,MA0130.1;0,MA0131.1;0.531427,MA0132.1;0,MA0133.1;0,MA0135.1;0.838263,MA0136.1;0.408073,MA0139.1;0.297344,MA0140.1;0.379562,MA0141.1;0.603844,MA0142.1;0.604892,MA0143.1;0.467531,MA0144.1;0.129525,MA0145.1;0.0257706,MA0146.1;0.266418,MA0147.1;0.138228,MA0148.1;0.851609,MA0149.1;2.75689,MA0062.2;0.0662974,MA0035.2;0.383789,MA0039.2;0.00920605,MA0138.2;0.523978,MA0002.2;0.302282,MA0137.2;0.598347,MA0104.2;0.326825,MA0047.2;0.431964,MA0112.2;0.025769,MA0065.2;0.4963,MA0150.1;0.290598,MA0151.1;0,MA0152.1;0.432062,MA0153.1;0.854464,MA0154.1;0.670722,MA0155.1;0.0312913,MA0156.1;0.200311,MA0157.1;0.574484,MA0158.1;0,MA0159.1;0.145521,MA0160.1;0.320315,MA0161.1;0,MA0162.1;0.0257461,MA0163.1;0.692813,MA0164.1;0.408402,MA0080.2;0.190316,MA0018.2;0.417217,MA0099.2;0.518072,MA0079.2;1.35452,MA0102.2;1.42135,MA0258.1;0.118033,MA0259.1;0.408856,MA0442.1;0}} | ||
Latest revision as of 15:34, 17 September 2013
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr11:118165162..118165220,- | p@chr11:118165162..118165220 - |
| Mm9::chr11:5763981..5764006,+ | p@chr11:5763981..5764006 + |
| Mm9::chr11:5770554..5770565,+ | p@chr11:5770554..5770565 + |
| Mm9::chr11:5771774..5771785,+ | p@chr11:5771774..5771785 + |
| Mm9::chr17:29227914..29227965,+ | p2@Cdkn1a |
| Mm9::chr1:137662795..137662802,+ | p3@Phlda3 |
| Mm9::chr1:137662818..137662834,+ | p2@Phlda3 |
| Mm9::chr4:88920480..88920487,- | p@chr4:88920480..88920487 - |
| Mm9::chr4:88928017..88928055,- | p2@Cdkn2a |
| Mm9::chr4:88928056..88928065,- | p4@Cdkn2a |
| Mm9::chr7:74764902..74764914,- | p@chr7:74764902..74764914 - |
| Mm9::chr9:58095257..58095272,- | p@chr9:58095257..58095272 - |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0045736 | negative regulation of cyclin-dependent protein kinase activity | 6.23135703143626e-06 |
| GO:0004861 | cyclin-dependent protein kinase inhibitor activity | 1.45398330733513e-05 |
| GO:0000079 | regulation of cyclin-dependent protein kinase activity | 1.90402575960552e-05 |
| GO:0004860 | protein kinase inhibitor activity | 3.9984540951716e-05 |
| GO:0030888 | regulation of B cell proliferation | 3.9984540951716e-05 |
| GO:0019210 | kinase inhibitor activity | 3.9984540951716e-05 |
| GO:0042100 | B cell proliferation | 5.20763409055744e-05 |
| GO:0006469 | negative regulation of protein kinase activity | 6.63733938348437e-05 |
| GO:0033673 | negative regulation of kinase activity | 6.63733938348437e-05 |
| GO:0050864 | regulation of B cell activation | 6.63733938348437e-05 |
| GO:0051348 | negative regulation of transferase activity | 6.63733938348437e-05 |
| GO:0007050 | cell cycle arrest | 8.56811591822485e-05 |
| GO:0043086 | negative regulation of catalytic activity | 8.63602173202896e-05 |
| GO:0050670 | regulation of lymphocyte proliferation | 9.5408999881324e-05 |
| GO:0032944 | regulation of mononuclear cell proliferation | 9.5408999881324e-05 |
| GO:0019887 | protein kinase regulator activity | 0.000126769169608281 |
| GO:0032943 | mononuclear cell proliferation | 0.000147639432823766 |
| GO:0019207 | kinase regulator activity | 0.000147639432823766 |
| GO:0046651 | lymphocyte proliferation | 0.000147639432823766 |
| GO:0051249 | regulation of lymphocyte activation | 0.000172542499620451 |
| GO:0042113 | B cell activation | 0.000172542499620451 |
| GO:0050865 | regulation of cell activation | 0.000172542499620451 |
| GO:0045786 | negative regulation of progression through cell cycle | 0.000298715677694475 |
| GO:0008285 | negative regulation of cell proliferation | 0.000298715677694475 |
| GO:0045859 | regulation of protein kinase activity | 0.00033238058405681 |
| GO:0043549 | regulation of kinase activity | 0.000345360980088448 |
| GO:0051338 | regulation of transferase activity | 0.000347917434255191 |
| GO:0000074 | regulation of progression through cell cycle | 0.000584300995929853 |
| GO:0046649 | lymphocyte activation | 0.00059236837780091 |
| GO:0043071 | positive regulation of non-apoptotic programmed cell death | 0.00059236837780091 |
| GO:0016244 | non-apoptotic programmed cell death | 0.00059236837780091 |
| GO:0043070 | regulation of non-apoptotic programmed cell death | 0.00059236837780091 |
| GO:0045321 | leukocyte activation | 0.000644975998621454 |
| GO:0004857 | enzyme inhibitor activity | 0.000644975998621454 |
| GO:0001775 | cell activation | 0.000721353759210549 |
| GO:0050790 | regulation of catalytic activity | 0.000997645726835604 |
| GO:0033087 | negative regulation of immature T cell proliferation | 0.000997645726835604 |
| GO:0033088 | negative regulation of immature T cell proliferation in the thymus | 0.000997645726835604 |
| GO:0051239 | regulation of multicellular organismal process | 0.0010253245289803 |
| GO:0065009 | regulation of a molecular function | 0.001243545187586 |
| GO:0042127 | regulation of cell proliferation | 0.00126871442388828 |
| GO:0030332 | cyclin binding | 0.00135391068072313 |
| GO:0051726 | regulation of cell cycle | 0.00147511678563941 |
| GO:0033080 | immature T cell proliferation in the thymus | 0.001613125978755 |
| GO:0033079 | immature T cell proliferation | 0.001613125978755 |
| GO:0033083 | regulation of immature T cell proliferation | 0.001613125978755 |
| GO:0033084 | regulation of immature T cell proliferation in the thymus | 0.001613125978755 |
| GO:0008283 | cell proliferation | 0.00230410917234263 |
| GO:0048103 | somatic stem cell division | 0.00232079898255502 |
| GO:0000307 | cyclin-dependent protein kinase holoenzyme complex | 0.00265337413755587 |
| GO:0030889 | negative regulation of B cell proliferation | 0.00297288676570365 |
| GO:0022402 | cell cycle process | 0.00303730721766891 |
| GO:0017145 | stem cell division | 0.00321820197480138 |
| GO:0006915 | apoptosis | 0.00347919357513534 |
| GO:0012501 | programmed cell death | 0.00353046029921064 |
| GO:0050869 | negative regulation of B cell activation | 0.00363859322660616 |
| GO:0008219 | cell death | 0.00363859322660616 |
| GO:0016265 | death | 0.00363859322660616 |
| GO:0007569 | cell aging | 0.00410573729206283 |
| GO:0030890 | positive regulation of B cell proliferation | 0.00410573729206283 |
| GO:0007049 | cell cycle | 0.00412965310414495 |
| GO:0002376 | immune system process | 0.00431174729559889 |
| GO:0048523 | negative regulation of cellular process | 0.00550853610086116 |
| GO:0050672 | negative regulation of lymphocyte proliferation | 0.00553819046196241 |
| GO:0032945 | negative regulation of mononuclear cell proliferation | 0.00553819046196241 |
| GO:0016301 | kinase activity | 0.00562450782962479 |
| GO:0048519 | negative regulation of biological process | 0.00598149821554142 |
| GO:0009411 | response to UV | 0.00676547334841651 |
| GO:0033077 | T cell differentiation in the thymus | 0.00676547334841651 |
| GO:0051250 | negative regulation of lymphocyte activation | 0.00676547334841651 |
| GO:0016772 | transferase activity, transferring phosphorus-containing groups | 0.00684045775682157 |
| GO:0050871 | positive regulation of B cell activation | 0.00684045775682157 |
| GO:0007568 | aging | 0.00726533549337855 |
| GO:0048468 | cell development | 0.00859156771462019 |
| GO:0032946 | positive regulation of mononuclear cell proliferation | 0.00897044840445193 |
| GO:0050671 | positive regulation of lymphocyte proliferation | 0.00897044840445193 |
| GO:0042129 | regulation of T cell proliferation | 0.0103279077926027 |
| GO:0016072 | rRNA metabolic process | 0.0126990586550902 |
| GO:0006364 | rRNA processing | 0.0126990586550902 |
| GO:0042098 | T cell proliferation | 0.013012826050804 |
| GO:0051251 | positive regulation of lymphocyte activation | 0.014078079385034 |
| GO:0030217 | T cell differentiation | 0.014078079385034 |
| GO:0050863 | regulation of T cell activation | 0.0143636908787096 |
| GO:0009416 | response to light stimulus | 0.0164409904305137 |
| GO:0048869 | cellular developmental process | 0.0169711008751167 |
| GO:0030154 | cell differentiation | 0.0169711008751167 |
| GO:0016740 | transferase activity | 0.0177298342497547 |
| GO:0030098 | lymphocyte differentiation | 0.0197578127502482 |
| GO:0009314 | response to radiation | 0.0197578127502482 |
| GO:0008544 | epidermis development | 0.0201668869473389 |
| GO:0007398 | ectoderm development | 0.0209812073796822 |
| GO:0005730 | nucleolus | 0.0219823875503924 |
| GO:0042110 | T cell activation | 0.0239743421323824 |
| GO:0042254 | ribosome biogenesis and assembly | 0.0249212517907133 |
| GO:0002521 | leukocyte differentiation | 0.0252534270819102 |
| GO:0043066 | negative regulation of apoptosis | 0.0293016798776038 |
| GO:0043069 | negative regulation of programmed cell death | 0.0293872403622387 |
| GO:0043068 | positive regulation of programmed cell death | 0.031771972700846 |
| GO:0009628 | response to abiotic stimulus | 0.0320202372355373 |
| GO:0008284 | positive regulation of cell proliferation | 0.0332022488739404 |
| GO:0022613 | ribonucleoprotein complex biogenesis and assembly | 0.0352890386214833 |
| GO:0030097 | hemopoiesis | 0.038435743270726 |
| GO:0032502 | developmental process | 0.0396246347091916 |
| GO:0006974 | response to DNA damage stimulus | 0.0415787003990648 |
| GO:0048534 | hemopoietic or lymphoid organ development | 0.0415787003990648 |
| GO:0051301 | cell division | 0.0415787003990648 |
| GO:0002520 | immune system development | 0.0435798320167287 |
| GO:0009719 | response to endogenous stimulus | 0.0435798320167287 |
| GO:0050794 | regulation of cellular process | 0.046956514775283 |
| GO:0009888 | tissue development | 0.048051995656815 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| migratory neural crest cell | 8.91e-12 | 10 |
| neuron associated cell | 8.91e-12 | 10 |
| glial cell (sensu Vertebrata) | 8.91e-12 | 10 |
| neuron associated cell (sensu Vertebrata) | 8.91e-12 | 10 |
| glial cell | 8.91e-12 | 10 |
| glioblast | 8.91e-12 | 10 |
| glioblast (sensu Vertebrata) | 8.91e-12 | 10 |
| autonomic neuron | 9.73e-11 | 9 |
| oligodendrocyte precursor cell | 3.26e-10 | 8 |
| non-terminally differentiated cell | 4.60e-10 | 49 |
| mesodermal cell | 5.40e-09 | 7 |
| muscle precursor cell | 2.29e-08 | 6 |
| contractile cell | 2.29e-08 | 6 |
| muscle cell | 2.29e-08 | 6 |
| myoblast | 2.29e-08 | 6 |
| oligodendrocyte | 7.39e-08 | 6 |
| macroglial cell | 7.39e-08 | 6 |
| astrocyte | 7.39e-08 | 6 |
| Ontology term | p-value | n |
|---|---|---|
| peripheral nervous system | 2.56e-12 | 11 |
| autonomic nervous system | 9.73e-11 | 9 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.829197 |
| MA0004.1 | 0.303605 |
| MA0006.1 | 0.16569 |
| MA0007.1 | 0.790701 |
| MA0009.1 | 0.709264 |
| MA0014.1 | 1.34901 |
| MA0017.1 | 0.546298 |
| MA0019.1 | 0.535691 |
| MA0024.1 | 0.667197 |
| MA0025.1 | 0.936082 |
| MA0027.1 | 2.34178 |
| MA0028.1 | 0.173587 |
| MA0029.1 | 1.55834 |
| MA0030.1 | 0.65267 |
| MA0031.1 | 0.618697 |
| MA0038.1 | 0.432665 |
| MA0040.1 | 0.721328 |
| MA0041.1 | 0.239557 |
| MA0042.1 | 0.228771 |
| MA0043.1 | 0.802848 |
| MA0046.1 | 0.743934 |
| MA0048.1 | 0.168666 |
| MA0050.1 | 0.337476 |
| MA0051.1 | 0.440863 |
| MA0052.1 | 0.729105 |
| MA0055.1 | 0.10681 |
| MA0056.1 | 0 |
| MA0057.1 | 0.630087 |
| MA0058.1 | 0.223242 |
| MA0059.1 | 0.233271 |
| MA0060.1 | 0.351437 |
| MA0061.1 | 0.40468 |
| MA0063.1 | 0 |
| MA0066.1 | 1.08293 |
| MA0067.1 | 1.04514 |
| MA0068.1 | 0.0405002 |
| MA0069.1 | 0.729433 |
| MA0070.1 | 0.720077 |
| MA0071.1 | 0.336739 |
| MA0072.1 | 0.711905 |
| MA0073.1 | 1.47506 |
| MA0074.1 | 0.390075 |
| MA0076.1 | 0.200996 |
| MA0077.1 | 0.691048 |
| MA0078.1 | 0.471303 |
| MA0081.1 | 0.702944 |
| MA0083.1 | 0.802078 |
| MA0084.1 | 1.3693 |
| MA0087.1 | 0.760279 |
| MA0088.1 | 1.08862 |
| MA0089.1 | 0 |
| MA0090.1 | 1.38006 |
| MA0091.1 | 0.315003 |
| MA0092.1 | 0.274547 |
| MA0093.1 | 0.179936 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.379666 |
| MA0101.1 | 0.240622 |
| MA0103.1 | 0.19444 |
| MA0105.1 | 0.226879 |
| MA0106.1 | 6.61172 |
| MA0107.1 | 0.189625 |
| MA0108.2 | 0.557195 |
| MA0109.1 | 0 |
| MA0111.1 | 0.78079 |
| MA0113.1 | 0.452439 |
| MA0114.1 | 0.400482 |
| MA0115.1 | 0.805567 |
| MA0116.1 | 0.165534 |
| MA0117.1 | 0.774259 |
| MA0119.1 | 0.676816 |
| MA0122.1 | 0.793507 |
| MA0124.1 | 0.992825 |
| MA0125.1 | 0.920215 |
| MA0130.1 | 0 |
| MA0131.1 | 0.531427 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.838263 |
| MA0136.1 | 0.408073 |
| MA0139.1 | 0.297344 |
| MA0140.1 | 0.379562 |
| MA0141.1 | 0.603844 |
| MA0142.1 | 0.604892 |
| MA0143.1 | 0.467531 |
| MA0144.1 | 0.129525 |
| MA0145.1 | 0.0257706 |
| MA0146.1 | 0.266418 |
| MA0147.1 | 0.138228 |
| MA0148.1 | 0.851609 |
| MA0149.1 | 2.75689 |
| MA0062.2 | 0.0662974 |
| MA0035.2 | 0.383789 |
| MA0039.2 | 0.00920605 |
| MA0138.2 | 0.523978 |
| MA0002.2 | 0.302282 |
| MA0137.2 | 0.598347 |
| MA0104.2 | 0.326825 |
| MA0047.2 | 0.431964 |
| MA0112.2 | 0.025769 |
| MA0065.2 | 0.4963 |
| MA0150.1 | 0.290598 |
| MA0151.1 | 0 |
| MA0152.1 | 0.432062 |
| MA0153.1 | 0.854464 |
| MA0154.1 | 0.670722 |
| MA0155.1 | 0.0312913 |
| MA0156.1 | 0.200311 |
| MA0157.1 | 0.574484 |
| MA0158.1 | 0 |
| MA0159.1 | 0.145521 |
| MA0160.1 | 0.320315 |
| MA0161.1 | 0 |
| MA0162.1 | 0.0257461 |
| MA0163.1 | 0.692813 |
| MA0164.1 | 0.408402 |
| MA0080.2 | 0.190316 |
| MA0018.2 | 0.417217 |
| MA0099.2 | 0.518072 |
| MA0079.2 | 1.35452 |
| MA0102.2 | 1.42135 |
| MA0258.1 | 0.118033 |
| MA0259.1 | 0.408856 |
| MA0442.1 | 0 |
