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MCL coexpression mm9:1156: Difference between revisions

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{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0047276;N-acetyllactosaminide 3-alpha-galactosyltransferase activity;0.015942584780584;14594!GO:0030676;Rac guanyl-nucleotide exchange factor activity;0.0239112568070353;22324!
|ontology_enrichment_celltype=CL:0000049!5.82e-08!19
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002193!3.90e-14!48;UBERON:0002405!3.90e-14!48;UBERON:0002390!8.78e-13!45;UBERON:0003061!8.78e-13!45;UBERON:0002371!1.09e-10!16;UBERON:0001474!2.10e-10!22;UBERON:0004765!2.10e-10!22;UBERON:0001434!2.10e-10!22;UBERON:0002204!3.20e-08!32;UBERON:0003081!7.24e-08!87;UBERON:0000926!2.26e-07!120;UBERON:0004120!2.26e-07!120;UBERON:0006603!2.26e-07!120
}}

Latest revision as of 16:29, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr17:10511185..10511202,+p@chr17:10511185..10511202
+
Mm9::chr17:57418593..57418604,+p2@Vav1
Mm9::chr1:89537750..89537753,+p@chr1:89537750..89537753
+
Mm9::chr2:35318238..35318241,-p@chr2:35318238..35318241
-
Mm9::chr2:35318313..35318352,-p5@Ggta1
Mm9::chrX:83115605..83115636,+p1@5430427O19Rik
Mm9::chrX:83115663..83115674,+p3@5430427O19Rik


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0047276N-acetyllactosaminide 3-alpha-galactosyltransferase activity0.015942584780584
GO:0030676Rac guanyl-nucleotide exchange factor activity0.0239112568070353



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
common myeloid progenitor5.82e-0819

Uber Anatomy
Ontology termp-valuen
hemolymphoid system3.90e-1448
immune system3.90e-1448
hematopoietic system8.78e-1345
blood island8.78e-1345
bone marrow1.09e-1016
bone element2.10e-1022
skeletal element2.10e-1022
skeletal system2.10e-1022
musculoskeletal system3.20e-0832
lateral plate mesoderm7.24e-0887
mesoderm2.26e-07120
mesoderm-derived structure2.26e-07120
presumptive mesoderm2.26e-07120


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.188259
MA0004.10.481116
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.10.222567
MA0017.10.337808
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.128106
MA0050.12.22815
MA0051.11.53797
MA0052.10.945011
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