Coexpression cluster:C120

Full id: C120_immature_salivary_tongue_skin_cervical_CD14_CD34

Phase1 CAGE Peaks

Hg19::chr10:103893775..103893800,-	p@chr10:103893775..103893800 -
Hg19::chr10:135337169..135337187,-	p@chr10:135337169..135337187 -
Hg19::chr10:135337234..135337244,-	p@chr10:135337234..135337244 -
Hg19::chr10:135337292..135337307,-	p@chr10:135337292..135337307 -
Hg19::chr10:81701830..81701837,-	p@chr10:81701830..81701837 -
Hg19::chr10:85954269..85954280,+	p4@CDHR1
Hg19::chr10:85954282..85954314,+	p1@CDHR1
Hg19::chr10:97592419..97592428,+	p@chr10:97592419..97592428 +
Hg19::chr11:108408895..108408924,-	p3@EXPH5
Hg19::chr11:113258495..113258506,+	p1@ANKK1
Hg19::chr11:12214399..12214404,-	p@chr11:12214399..12214404 -
Hg19::chr11:12214548..12214586,+	p@chr11:12214548..12214586 +
Hg19::chr11:57543275..57543296,+	p@chr11:57543275..57543296 +
Hg19::chr11:62311004..62311025,+	p@chr11:62311004..62311025 +
Hg19::chr11:65363259..65363275,-	p1@KCNK7
Hg19::chr12:112587704..112587710,+	p@chr12:112587704..112587710 +
Hg19::chr12:322653..322665,-	p8@SLC6A12
Hg19::chr12:52541319..52541358,+	p@chr12:52541319..52541358 +
Hg19::chr12:53045991..53045996,-	p1@KRT2
Hg19::chr12:53268328..53268340,+	p@chr12:53268328..53268340 +
Hg19::chr13:23490561..23490568,-	p1@ENST00000379093
Hg19::chr13:78130718..78130733,+	p@chr13:78130718..78130733 +
Hg19::chr13:79979347..79979384,+	p@chr13:79979347..79979384 +
Hg19::chr14:104583456..104583460,+	p1@MIR203
Hg19::chr14:24017647..24017657,-	p15@ZFHX2
Hg19::chr14:50234166..50234170,+	p6@KLHDC2
Hg19::chr14:67879076..67879080,+	p@chr14:67879076..67879080 +
Hg19::chr14:69192856..69192867,-	p@chr14:69192856..69192867 -
Hg19::chr14:69223811..69223817,+	p@chr14:69223811..69223817 +
Hg19::chr14:94833955..94833966,+	p@chr14:94833955..94833966 +
Hg19::chr15:42313237..42313242,-	p@chr15:42313237..42313242 -
Hg19::chr15:42448788..42448849,-	p1@PLA2G4F
Hg19::chr15:59949497..59949508,-	p3@GTF2A2
Hg19::chr16:10915414..10915421,+	p@chr16:10915414..10915421 +
Hg19::chr16:10953616..10953637,+	p@chr16:10953616..10953637 +
Hg19::chr16:10970721..10970727,-	p@chr16:10970721..10970727 -
Hg19::chr16:1257038..1257050,+	p@chr16:1257038..1257050 +
Hg19::chr16:31454377..31454381,+	p@chr16:31454377..31454381 +
Hg19::chr16:33722353..33722359,+	p@chr16:33722353..33722359 +
Hg19::chr16:34571309..34571314,-	p@chr16:34571309..34571314 -
Hg19::chr16:75018508..75018512,+	p@chr16:75018508..75018512 +
Hg19::chr16:85894104..85894112,-	p@chr16:85894104..85894112 -
Hg19::chr17:10009524..10009534,-	p@chr17:10009524..10009534 -
Hg19::chr17:10009535..10009542,-	p@chr17:10009535..10009542 -
Hg19::chr17:25874072..25874076,+	p@chr17:25874072..25874076 +
Hg19::chr17:29887192..29887207,-	p@chr17:29887192..29887207 -
Hg19::chr17:39812242..39812247,+	p@chr17:39812242..39812247 +
Hg19::chr17:48546232..48546247,-	p1@CHAD
Hg19::chr17:7154246..7154280,+	p@chr17:7154246..7154280 +
Hg19::chr17:7183607..7183612,-	p@chr17:7183607..7183612 -
Hg19::chr17:7819599..7819609,-	p1@ENST00000324348
Hg19::chr17:79874727..79874731,+	p@chr17:79874727..79874731 +
Hg19::chr18:13562948..13562955,+	p@chr18:13562948..13562955 +
Hg19::chr18:23806437..23806449,+	p2@TAF4B
Hg19::chr18:53545728..53545733,+	p@chr18:53545728..53545733 +
Hg19::chr18:53548086..53548099,-	p@chr18:53548086..53548099 -
Hg19::chr19:10024468..10024484,-	p@chr19:10024468..10024484 -
Hg19::chr19:1180737..1180757,+	p@chr19:1180737..1180757 +
Hg19::chr19:1180760..1180775,+	p@chr19:1180760..1180775 +
Hg19::chr19:1180783..1180800,+	p@chr19:1180783..1180800 +
Hg19::chr19:2090131..2090140,-	p@chr19:2090131..2090140 -
Hg19::chr19:33783896..33783902,+	p@chr19:33783896..33783902 +
Hg19::chr19:35481293..35481296,-	p@chr19:35481293..35481296 -
Hg19::chr19:40440897..40440908,-	p2@FCGBP
Hg19::chr19:55581103..55581143,-	p4@RDH13
Hg19::chr19:6062602..6062619,+	p@chr19:6062602..6062619 +
Hg19::chr19:6063658..6063670,-	p@chr19:6063658..6063670 -
Hg19::chr19:6063965..6063994,+	p@chr19:6063965..6063994 +
Hg19::chr19:9732460..9732472,-	p2@ZNF561
Hg19::chr1:1100457..1100470,+	p@chr1:1100457..1100470 +
Hg19::chr1:117602977..117602984,+	p3@TTF2
Hg19::chr1:11865532..11865537,-	p11@MTHFR
Hg19::chr1:152878978..152878994,+	p@chr1:152878978..152878994 +
Hg19::chr1:157926828..157926838,+	p@chr1:157926828..157926838 +
Hg19::chr1:158224235..158224244,+	p10@CD1A
Hg19::chr1:16481684..16481727,+	p1@ENST00000424774
Hg19::chr1:183442112..183442126,-	p@chr1:183442112..183442126 -
Hg19::chr1:19283116..19283132,-	p1@IFFO2
Hg19::chr1:19283143..19283154,-	p3@IFFO2
Hg19::chr1:212780312..212780339,+	p@chr1:212780312..212780339 +
Hg19::chr1:212780356..212780372,+	p@chr1:212780356..212780372 +
Hg19::chr1:27181551..27181558,-	p@chr1:27181551..27181558 -
Hg19::chr1:29270212..29270216,-	p@chr1:29270212..29270216 -
Hg19::chr1:39571788..39571799,-	p@chr1:39571788..39571799 -
Hg19::chr1:42902892..42902896,+	p@chr1:42902892..42902896 +
Hg19::chr1:85462278..85462283,+	p@chr1:85462278..85462283 +
Hg19::chr20:1762918..1762921,-	p@chr20:1762918..1762921 -
Hg19::chr20:19095317..19095322,+	p@chr20:19095317..19095322 +
Hg19::chr20:23117745..23117783,+	p@chr20:23117745..23117783 +
Hg19::chr20:24933916..24933922,-	p@chr20:24933916..24933922 -
Hg19::chr20:43588041..43588075,+	p@chr20:43588041..43588075 +
Hg19::chr20:44639343..44639375,+	p@chr20:44639343..44639375 +
Hg19::chr20:44639385..44639400,+	p@chr20:44639385..44639400 +
Hg19::chr2:122041216..122041223,-	p@chr2:122041216..122041223 -
Hg19::chr2:173867941..173867955,+	p@chr2:173867941..173867955 +
Hg19::chr2:208368220..208368233,+	p@chr2:208368220..208368233 +
Hg19::chr2:216002151..216002158,+	p@chr2:216002151..216002158 +
Hg19::chr2:216003243..216003282,-	p2@ABCA12
Hg19::chr2:216003447..216003472,+	p@chr2:216003447..216003472 +
Hg19::chr2:230990020..230990046,+	p1@ENST00000445199
Hg19::chr2:38948032..38948038,-	p@chr2:38948032..38948038 -
Hg19::chr2:64587249..64587257,-	p@chr2:64587249..64587257 -
Hg19::chr2:64680581..64680593,+	p@chr2:64680581..64680593 +
Hg19::chr2:64680611..64680624,+	p11@LGALSL
Hg19::chr2:71057780..71057794,-	p@chr2:71057780..71057794 -
Hg19::chr2:71057873..71057874,-	p@chr2:71057873..71057874 -
Hg19::chr2:71058922..71058927,-	p@chr2:71058922..71058927 -
Hg19::chr2:73340735..73340740,-	p@chr2:73340735..73340740 -
Hg19::chr3:186252359..186252380,+	p@chr3:186252359..186252380 +
Hg19::chr3:52099097..52099134,-	p1@C3orf74
Hg19::chr3:71080443..71080455,-	p@chr3:71080443..71080455 -
Hg19::chr3:71080630..71080635,+	p@chr3:71080630..71080635 +
Hg19::chr4:100484667..100484671,-	p8@RG9MTD2
Hg19::chr4:106817137..106817150,-	p4@INTS12
Hg19::chr4:108745881..108745897,+	p4@SGMS2
Hg19::chr4:159149804..159149824,-	p@chr4:159149804..159149824 -
Hg19::chr4:3392220..3392256,+	p@chr4:3392220..3392256 +
Hg19::chr5:133773054..133773060,+	p@chr5:133773054..133773060 +
Hg19::chr5:159933217..159933221,-	p@chr5:159933217..159933221 -
Hg19::chr5:79551098..79551103,+	p@chr5:79551098..79551103 +
Hg19::chr6:10413321..10413336,+	p@chr6:10413321..10413336 +
Hg19::chr6:10413345..10413356,+	p@chr6:10413345..10413356 +
Hg19::chr6:106943050..106943075,+	p@chr6:106943050..106943075 +
Hg19::chr6:122532780..122532793,+	p1@RNU1-18P
Hg19::chr6:132452229..132452234,+	p@chr6:132452229..132452234 +
Hg19::chr6:138137434..138137443,+	p@chr6:138137434..138137443 +
Hg19::chr6:32140886..32140902,-	p26@AGPAT1
Hg19::chr6:32632755..32632783,-	p5@HLA-DQB1
Hg19::chr6:32729494..32729506,-	p1@M95729
Hg19::chr6:32729634..32729642,-	p2@M95729
Hg19::chr6:36992669..36992691,+	p@chr6:36992669..36992691 +
Hg19::chr7:2284179..2284201,+	p3@NUDT1
Hg19::chr7:39767535..39767539,+	p@chr7:39767535..39767539 +
Hg19::chr7:42928540..42928555,+	p@chr7:42928540..42928555 +
Hg19::chr7:55594397..55594400,+	p@chr7:55594397..55594400 +
Hg19::chr8:144261054..144261063,-	p@chr8:144261054..144261063 -
Hg19::chr8:22069222..22069228,+	p@chr8:22069222..22069228 +
Hg19::chr8:57233103..57233123,-	p2@SDR16C5
Hg19::chr8:62629856..62629862,+	p@chr8:62629856..62629862 +
Hg19::chr8:987779..987786,+	p@chr8:987779..987786 +
Hg19::chr9:109626921..109626926,-	p@chr9:109626921..109626926 -
Hg19::chr9:111314011..111314037,+	p@chr9:111314011..111314037 +
Hg19::chr9:134510706..134510711,-	p@chr9:134510706..134510711 -
Hg19::chr9:136004782..136004793,-	p23@RALGDS
Hg19::chr9:34662651..34662656,-	p1@CCL27
Hg19::chr9:87445344..87445355,+	p@chr9:87445344..87445355 +
Hg19::chrX:131156808..131156816,+	p6@MST4
Hg19::chrX:135838814..135838818,+	p@chrX:135838814..135838818 +
Hg19::chrY:27869488..27869491,+	p1@ENST00000516617

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016591	DNA-directed RNA polymerase II, holoenzyme	0.0331363952634676
GO:0044451	nucleoplasm part	0.0455375014718003
GO:0006644	phospholipid metabolic process	0.0455375014718003
GO:0005654	nucleoplasm	0.0455375014718003
GO:0032980	keratinocyte activation	0.0455375014718003
GO:0003717	RNA polymerase II transcription termination factor activity	0.0455375014718003
GO:0006643	membrane lipid metabolic process	0.0481807030480791
GO:0008413	8-oxo-7,8-dihydroguanine triphosphatase activity	0.0481807030480791
GO:0033188	sphingomyelin synthase activity	0.0481807030480791
GO:0047493	ceramide cholinephosphotransferase activity	0.0481807030480791
GO:0031981	nuclear lumen	0.0481807030480791
GO:0006352	transcription initiation	0.0481807030480791
GO:0008654	phospholipid biosynthetic process	0.0481807030480791
GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	0.0481807030480791
GO:0006654	phosphatidic acid biosynthetic process	0.0481807030480791
GO:0051546	keratinocyte migration	0.0481807030480791
GO:0006686	sphingomyelin biosynthetic process	0.0481807030480791

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n
CD14-positive, CD16-negative classical monocyte	5.51e-22	42
classical monocyte	4.41e-21	45
leukocyte	1.47e-15	140
myeloid leukocyte	1.72e-15	76
macrophage dendritic cell progenitor	1.53e-14	65
granulocyte monocyte progenitor cell	2.56e-14	71
monopoietic cell	2.00e-13	63
monocyte	2.00e-13	63
monoblast	2.00e-13	63
promonocyte	2.00e-13	63
myeloid lineage restricted progenitor cell	1.32e-11	70
nongranular leukocyte	3.40e-11	119
hematopoietic lineage restricted progenitor cell	1.95e-10	124
endo-epithelial cell	2.15e-09	43
hematopoietic stem cell	4.91e-09	172
angioblastic mesenchymal cell	4.91e-09	172
myeloid cell	2.23e-08	112
common myeloid progenitor	2.23e-08	112
hematopoietic cell	4.92e-08	182
hematopoietic oligopotent progenitor cell	7.90e-08	165
hematopoietic multipotent progenitor cell	7.90e-08	165
epithelial cell	1.38e-07	254

Uber Anatomy

Ontology term	p-value	n
hematopoietic system	3.85e-11	102
blood island	3.85e-11	102
bone marrow	6.61e-11	80
hemolymphoid system	2.03e-09	112
bone element	2.07e-09	86
adult organism	4.41e-08	115
organ	2.96e-07	511
respiratory system	6.86e-07	72

Disease

Ontology term	p-value	n
carcinoma	1.88e-07	106
squamous cell carcinoma	7.60e-07	14

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}

ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

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No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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