MCL coexpression mm9:926: Difference between revisions
From FANTOM5_SSTAR
No edit summary |
No edit summary |
||
Line 3: | Line 3: | ||
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0205563265474198,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0514985917256918,0.0977489550031698,0.197834725467095,0,0,0,0,0,0,0,0,0,0,0.054710539498653,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0971864084671021,0,0,0,0,0,0,0,0.0570741246689917,0.202551054548896,0.181721285172594,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0325594900422539,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0210591418683525,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0532734549622995,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.033106842853765,0,0,0,0,0,0,0,0,0,0,0,0,0.0133149461563917,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0387082368603573,0,0,0,0,0,0,0,0,0,0,0,0,1.13644074260755,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0950304347095075,0.0325029563895826,0.0254340553719351,0.0244872863598586,0.0330027737817202,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0365202021377223,0.0421752250554017,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0375226752578547,0.0388749848471105,0.0269518943326477,0.0121269368029194,0,0,0,0,0.0298193647598867,0,0,0,0,0,0,0.0364791508700876,0,0.0276517186754466,0,0,0.020400916685161,0,0,0,0,0,0,0.0380084440794953,0,0 | |coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0205563265474198,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0514985917256918,0.0977489550031698,0.197834725467095,0,0,0,0,0,0,0,0,0,0,0.054710539498653,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0971864084671021,0,0,0,0,0,0,0,0.0570741246689917,0.202551054548896,0.181721285172594,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0325594900422539,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0210591418683525,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0532734549622995,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.033106842853765,0,0,0,0,0,0,0,0,0,0,0,0,0.0133149461563917,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0387082368603573,0,0,0,0,0,0,0,0,0,0,0,0,1.13644074260755,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0950304347095075,0.0325029563895826,0.0254340553719351,0.0244872863598586,0.0330027737817202,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0365202021377223,0.0421752250554017,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0375226752578547,0.0388749848471105,0.0269518943326477,0.0121269368029194,0,0,0,0,0.0298193647598867,0,0,0,0,0,0,0.0364791508700876,0,0.0276517186754466,0,0,0.020400916685161,0,0,0,0,0,0,0.0380084440794953,0,0 | ||
|gostat_on_MCL_coexpression=GO:0004692;cGMP-dependent protein kinase activity;0.00971838531944563;19092!GO:0004690;cyclic nucleotide-dependent protein kinase activity;0.00971838531944563;19092!GO:0004908;interleukin-1 receptor activity;0.00971838531944563;17082!GO:0019966;interleukin-1 binding;0.00971838531944563;17082!GO:0019002;GMP binding;0.00971838531944563;19092!GO:0030553;cGMP binding;0.00971838531944563;19092!GO:0005952;cAMP-dependent protein kinase complex;0.00971838531944563;19092!GO:0008603;cAMP-dependent protein kinase regulator activity;0.0113371842039205;19092!GO:0030551;cyclic nucleotide binding;0.0159529763788705;19092!GO:0004907;interleukin receptor activity;0.0247194069537288;17082!GO:0019965;interleukin binding;0.0247194069537288;17082!GO:0019838;growth factor binding;0.0308310436698183;17082!GO:0004896;hematopoietin/interferon-class (D200-domain) cytokine receptor activity;0.0313591463294665;17082!GO:0019887;protein kinase regulator activity;0.0337087347741023;19092!GO:0019955;cytokine binding;0.0337087347741023;17082!GO:0019207;kinase regulator activity;0.0348969287172017;19092!GO:0045087;innate immune response;0.0394855055171229;17082! | |gostat_on_MCL_coexpression=GO:0004692;cGMP-dependent protein kinase activity;0.00971838531944563;19092!GO:0004690;cyclic nucleotide-dependent protein kinase activity;0.00971838531944563;19092!GO:0004908;interleukin-1 receptor activity;0.00971838531944563;17082!GO:0019966;interleukin-1 binding;0.00971838531944563;17082!GO:0019002;GMP binding;0.00971838531944563;19092!GO:0030553;cGMP binding;0.00971838531944563;19092!GO:0005952;cAMP-dependent protein kinase complex;0.00971838531944563;19092!GO:0008603;cAMP-dependent protein kinase regulator activity;0.0113371842039205;19092!GO:0030551;cyclic nucleotide binding;0.0159529763788705;19092!GO:0004907;interleukin receptor activity;0.0247194069537288;17082!GO:0019965;interleukin binding;0.0247194069537288;17082!GO:0019838;growth factor binding;0.0308310436698183;17082!GO:0004896;hematopoietin/interferon-class (D200-domain) cytokine receptor activity;0.0313591463294665;17082!GO:0019887;protein kinase regulator activity;0.0337087347741023;19092!GO:0019955;cytokine binding;0.0337087347741023;17082!GO:0019207;kinase regulator activity;0.0348969287172017;19092!GO:0045087;innate immune response;0.0394855055171229;17082! | ||
|ontology_enrichment_celltype=CL:0000192!4.75e-10!3;CL:0000359!4.75e-10!3;CL:0002539!4.75e-10!3;CL:0000514!4.75e-10!3;CL:0000680!1.64e-08!6;CL:0000183!1.64e-08!6;CL:0000187!1.64e-08!6;CL:0000056!1.64e-08!6;CL:0000222!2.75e-07!7 | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0000014!1.15e-13!5;UBERON:0001003!1.15e-13!5;UBERON:0002097!1.15e-13!5;UBERON:0002199!1.15e-13!5;UBERON:0007029!1.15e-13!5;UBERON:0007376!1.15e-13!5;UBERON:0002416!1.15e-13!5;UBERON:0007383!1.15e-13!5;UBERON:0001135!4.75e-10!3;UBERON:0004237!4.75e-10!3;UBERON:0004695!4.75e-10!3;UBERON:0002111!4.75e-10!3;UBERON:0004178!4.75e-10!3;UBERON:0000947!1.27e-07!4;UBERON:0001637!1.27e-07!4;UBERON:0004573!1.27e-07!4;UBERON:0003509!1.27e-07!4;UBERON:0004571!1.27e-07!4;UBERON:0010191!1.27e-07!4;UBERON:0004572!1.27e-07!4;UBERON:0003102!5.37e-07!22 | |||
}} | }} |
Revision as of 21:28, 11 October 2012
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr11:98909393..98909430,+ | p@chr11:98909393..98909430 + |
Mm9::chr17:64212390..64212429,+ | p@chr17:64212390..64212429 + |
Mm9::chr19:7613621..7613623,+ | p@chr19:7613621..7613623 + |
Mm9::chr1:40496487..40496494,+ | p3@Il1rl1 |
Mm9::chr1:40496612..40496633,+ | p1@Il1rl1 |
Mm9::chr3:151668462..151668472,- | p@chr3:151668462..151668472 - |
Mm9::chr5:99372782..99372792,- | p6@Prkg2 |
Mm9::chr8:87160297..87160316,+ | p@chr8:87160297..87160316 + |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0004692 | cGMP-dependent protein kinase activity | 0.00971838531944563 |
GO:0004690 | cyclic nucleotide-dependent protein kinase activity | 0.00971838531944563 |
GO:0004908 | interleukin-1 receptor activity | 0.00971838531944563 |
GO:0019966 | interleukin-1 binding | 0.00971838531944563 |
GO:0019002 | GMP binding | 0.00971838531944563 |
GO:0030553 | cGMP binding | 0.00971838531944563 |
GO:0005952 | cAMP-dependent protein kinase complex | 0.00971838531944563 |
GO:0008603 | cAMP-dependent protein kinase regulator activity | 0.0113371842039205 |
GO:0030551 | cyclic nucleotide binding | 0.0159529763788705 |
GO:0004907 | interleukin receptor activity | 0.0247194069537288 |
GO:0019965 | interleukin binding | 0.0247194069537288 |
GO:0019838 | growth factor binding | 0.0308310436698183 |
GO:0004896 | hematopoietin/interferon-class (D200-domain) cytokine receptor activity | 0.0313591463294665 |
GO:0019887 | protein kinase regulator activity | 0.0337087347741023 |
GO:0019955 | cytokine binding | 0.0337087347741023 |
GO:0019207 | kinase regulator activity | 0.0348969287172017 |
GO:0045087 | innate immune response | 0.0394855055171229 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
smooth muscle cell | 4.75e-10 | 3 |
vascular associated smooth muscle cell | 4.75e-10 | 3 |
aortic smooth muscle cell | 4.75e-10 | 3 |
smooth muscle myoblast | 4.75e-10 | 3 |
muscle precursor cell | 1.64e-08 | 6 |
contractile cell | 1.64e-08 | 6 |
muscle cell | 1.64e-08 | 6 |
myoblast | 1.64e-08 | 6 |
mesodermal cell | 2.75e-07 | 7 |
Ontology term | p-value | n |
---|---|---|
zone of skin | 1.15e-13 | 5 |
skin epidermis | 1.15e-13 | 5 |
skin of body | 1.15e-13 | 5 |
integument | 1.15e-13 | 5 |
surface | 1.15e-13 | 5 |
outer epithelium | 1.15e-13 | 5 |
integumental system | 1.15e-13 | 5 |
enveloping layer of ectoderm | 1.15e-13 | 5 |
smooth muscle tissue | 4.75e-10 | 3 |
blood vessel smooth muscle | 4.75e-10 | 3 |
arterial system smooth muscle | 4.75e-10 | 3 |
artery smooth muscle tissue | 4.75e-10 | 3 |
aorta smooth muscle tissue | 4.75e-10 | 3 |
aorta | 1.27e-07 | 4 |
artery | 1.27e-07 | 4 |
systemic artery | 1.27e-07 | 4 |
arterial blood vessel | 1.27e-07 | 4 |
systemic arterial system | 1.27e-07 | 4 |
aortic system | 1.27e-07 | 4 |
arterial system | 1.27e-07 | 4 |
surface structure | 5.37e-07 | 22 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |