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Coexpression cluster:C251

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Full id: C251_gall_tonsil_trachea_CD14_salivary_throat_tongue



Phase1 CAGE Peaks

Hg19::chr11:1244263..1244268,+p18@MUC5B
Hg19::chr11:1244288..1244302,+p1@MUC5B
Hg19::chr11:1246908..1246942,+p@chr11:1246908..1246942
+
Hg19::chr11:1248582..1248591,+p@chr11:1248582..1248591
+
Hg19::chr11:1249793..1249803,+p25@MUC5B
Hg19::chr11:1249994..1249999,+p30@MUC5B
Hg19::chr11:1251248..1251255,+p@chr11:1251248..1251255
+
Hg19::chr11:1252161..1252166,+p@chr11:1252161..1252166
+
Hg19::chr11:1260725..1260734,+p@chr11:1260725..1260734
+
Hg19::chr11:1262722..1262737,+p@chr11:1262722..1262737
+
Hg19::chr11:1262749..1262754,+p@chr11:1262749..1262754
+
Hg19::chr11:1262797..1262805,+p@chr11:1262797..1262805
+
Hg19::chr11:1262879..1262886,+p@chr11:1262879..1262886
+
Hg19::chr11:1262959..1262968,-p@chr11:1262959..1262968
-
Hg19::chr11:1263220..1263227,+p@chr11:1263220..1263227
+
Hg19::chr11:1263382..1263385,+p@chr11:1263382..1263385
+
Hg19::chr11:1263439..1263454,-p@chr11:1263439..1263454
-
Hg19::chr11:1263446..1263456,+p@chr11:1263446..1263456
+
Hg19::chr11:1263486..1263491,+p@chr11:1263486..1263491
+
Hg19::chr11:1263559..1263572,+p@chr11:1263559..1263572
+
Hg19::chr11:1263601..1263611,+p@chr11:1263601..1263611
+
Hg19::chr11:1263622..1263627,+p@chr11:1263622..1263627
+
Hg19::chr11:1263636..1263653,+p@chr11:1263636..1263653
+
Hg19::chr11:1263666..1263677,+p@chr11:1263666..1263677
+
Hg19::chr11:1263705..1263748,+p@chr11:1263705..1263748
+
Hg19::chr11:1263750..1263761,+p@chr11:1263750..1263761
+
Hg19::chr11:1263767..1263777,+p@chr11:1263767..1263777
+
Hg19::chr11:1263870..1263886,+p@chr11:1263870..1263886
+
Hg19::chr11:1265985..1265990,+p@chr11:1265985..1265990
+
Hg19::chr11:1267070..1267081,+p9@MUC5B
Hg19::chr11:1267131..1267141,+p20@MUC5B
Hg19::chr11:1267642..1267655,+p17@MUC5B
Hg19::chr11:1267665..1267678,+p7@MUC5B
Hg19::chr11:1267685..1267693,+p26@MUC5B
Hg19::chr11:1267694..1267708,+p10@MUC5B
Hg19::chr11:1267812..1267847,+p15@MUC5B
Hg19::chr11:1270881..1270911,+p13@MUC5B
Hg19::chr11:1271068..1271087,+p11@MUC5B
Hg19::chr11:1272208..1272220,+p2@MUC5B
Hg19::chr11:1272233..1272254,+p3@MUC5B
Hg19::chr11:1272348..1272371,+p5@MUC5B
Hg19::chr11:1272387..1272410,+p6@MUC5B
Hg19::chr11:1272505..1272518,+p22@MUC5B
Hg19::chr11:1272548..1272559,+p8@MUC5B
Hg19::chr11:1275337..1275348,+p16@MUC5B
Hg19::chr11:1275383..1275393,+p27@MUC5B
Hg19::chr11:1276056..1276069,+p@chr11:1276056..1276069
+
Hg19::chr11:1276071..1276078,+p@chr11:1276071..1276078
+
Hg19::chr20:31611160..31611167,+p5@BPIFB6
Hg19::chr20:31611175..31611184,+p6@BPIFB6
Hg19::chr9:140331458..140331471,-p@chr9:140331458..140331471
-
Hg19::chr9:140331478..140331491,-p@chr9:140331478..140331491
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005201extracellular matrix structural constituent0.0217237725185447
GO:0030414protease inhibitor activity0.023489932885906
GO:0004857enzyme inhibitor activity0.0236076769103968
GO:0007155cell adhesion0.033910279053338
GO:0022610biological adhesion0.033910279053338



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
open tracheal system trachea5.58e-252
tongue1.61e-163
gustatory system1.61e-163
future tongue1.61e-163
tonsil1.82e-131
mucosa-associated lymphoid tissue1.82e-131
lymphoid tissue1.82e-131
tonsillar ring1.82e-131
oral opening2.42e-1322
submandibular gland6.06e-131
submandibular gland primordium6.06e-131
foregut3.11e-1287
orifice2.11e-1136
chordate pharynx3.15e-1110
pharyngeal region of foregut3.15e-1110
subdivision of digestive tract1.79e-10118
pharynx2.94e-1011
mouth4.17e-1029
stomodeum4.17e-1029
digestive system5.46e-10145
digestive tract5.46e-10145
primitive gut5.46e-10145
respiratory system2.30e-0974
adult organism4.61e-09114
endoderm-derived structure6.67e-09160
endoderm6.67e-09160
presumptive endoderm6.67e-09160
saliva-secreting gland8.57e-096
gland of oral region8.57e-096
gland of foregut8.57e-096
oral gland8.57e-096
oral cavity8.57e-096
segment of respiratory tract1.01e-0847
trachea8.35e-087
respiratory airway8.35e-087
respiratory tract1.54e-0754
major salivary gland4.17e-072
throat4.69e-072
Disease
Ontology termp-valuen
signet ring cell adenocarcinoma5.28e-072


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data