MCL coexpression mm9:1349

Phase1 CAGE Peaks

	Short description
Mm9::chr13:56849145..56849162,+	p@chr13:56849145..56849162 +
Mm9::chr14:35033214..35033244,+	p1@Syt15
Mm9::chr15:3532624..3532677,-	p4@Ghr
Mm9::chr5:151930051..151930066,-	p@chr5:151930051..151930066 -
Mm9::chr5:151930128..151930142,-	p@chr5:151930128..151930142 -
Mm9::chr5:151930148..151930172,-	p@chr5:151930148..151930172 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004903	growth hormone receptor activity	0.00493056125112394
GO:0017046	peptide hormone binding	0.00493056125112394
GO:0042562	hormone binding	0.0115030670703289
GO:0000299	integral to membrane of membrane fraction	0.0147876315703311
GO:0008021	synaptic vesicle	0.0443118372046809
GO:0004896	hematopoietin/interferon-class (D200-domain) cytokine receptor activity	0.0443118372046809
GO:0019898	extrinsic to membrane	0.0455177331093935
GO:0030136	clathrin-coated vesicle	0.0455177331093935
GO:0030135	coated vesicle	0.0475511073031396

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
anatomical space	6.09e-11	57
lung	2.14e-09	14
respiratory tube	2.14e-09	14
respiration organ	2.14e-09	14
pair of lungs	2.14e-09	14
lung primordium	2.14e-09	14
lung bud	2.14e-09	14
pancreas	3.05e-09	12
multi-cellular organism	4.08e-09	333
epithelial bud	5.82e-08	17
trunk region element	2.15e-07	79
tissue	3.57e-07	349
trunk	3.73e-07	90
viscus	4.69e-07	19
anatomical cavity	5.08e-07	39
immaterial anatomical entity	5.30e-07	79
body cavity precursor	6.44e-07	38
body cavity	7.15e-07	37
body cavity or lining	7.15e-07	37

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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