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Coexpression cluster:C405

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Full id: C405_Keratinocyte_Mammary_Sebocyte_tongue_Corneal_Mallassezderived_Gingival



Phase1 CAGE Peaks

Hg19::chr10:105791095..105791110,-p@chr10:105791095..105791110
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Hg19::chr12:52818230..52818265,-p@chr12:52818230..52818265
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Hg19::chr12:52828147..52828164,-p1@KRT75
Hg19::chr12:52840461..52840467,-p@chr12:52840461..52840467
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Hg19::chr12:52840473..52840479,-p@chr12:52840473..52840479
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Hg19::chr12:52840487..52840511,-p@chr12:52840487..52840511
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Hg19::chr12:52840896..52840905,-p@chr12:52840896..52840905
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Hg19::chr12:52845923..52845938,-p1@KRT6B
Hg19::chr12:52880994..52881011,-p@chr12:52880994..52881011
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Hg19::chr12:52908395..52908409,-p@chr12:52908395..52908409
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Hg19::chr12:52908434..52908443,-p@chr12:52908434..52908443
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Hg19::chr15:99637405..99637416,+p@chr15:99637405..99637416
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Hg19::chr17:19702846..19702866,-p@chr17:19702846..19702866
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Hg19::chr17:38632125..38632156,-p@chr17:38632125..38632156
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Hg19::chr17:39775719..39775763,-p@chr17:39775719..39775763
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Hg19::chr17:73753856..73753871,+p1@CU674593
Hg19::chr18:49762639..49762676,-p@chr18:49762639..49762676
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Hg19::chr19:46627914..46627955,-p1@IGFL3
Hg19::chr1:153533849..153533860,-p@chr1:153533849..153533860
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Hg19::chr1:153533861..153533893,-p@chr1:153533861..153533893
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Hg19::chr1:209788292..209788321,-p@chr1:209788292..209788321
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Hg19::chr5:134906504..134906518,-p@chr5:134906504..134906518
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Hg19::chr5:64400723..64400730,-p@chr5:64400723..64400730
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Hg19::chr9:108870138..108870152,+p1@uc004bcw.2
Hg19::chrY:7671750..7671771,-p@chrY:7671750..7671771
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0045111intermediate filament cytoskeleton0.00157857550617159
GO:0005882intermediate filament0.00157857550617159
GO:0044430cytoskeletal part0.0157589423587677
GO:0005856cytoskeleton0.0278905319402702
GO:0005200structural constituent of cytoskeleton0.0329455991167742
GO:0007398ectoderm development0.047072728176587



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
gingival epithelium1.04e-263
mouth mucosa1.02e-1013
epithelium of mucosa2.27e-108
gingiva2.27e-108
surface structure3.18e-1099
mouth4.63e-1029
stomodeum4.63e-1029
oral opening1.35e-0922
mammalian vulva1.91e-091
external female genitalia1.91e-091
mammary gland2.00e-094
mammary bud2.00e-094
mammary ridge2.00e-094
mammary placode2.00e-094
head1.36e-0856
orifice4.77e-0836
respiratory system7.53e-0874
subdivision of head1.04e-0749
anterior region of body1.17e-0762
craniocervical region1.17e-0762
mucosa5.22e-0720


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.