MCL coexpression mm9:111
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0044255 | cellular lipid metabolic process | 0.00776432066695159 |
| GO:0006629 | lipid metabolic process | 0.00854523667889149 |
| GO:0019842 | vitamin binding | 0.0242127072511119 |
| GO:0005739 | mitochondrion | 0.0242127072511119 |
| GO:0016866 | intramolecular transferase activity | 0.0242127072511119 |
| GO:0006073 | glucan metabolic process | 0.0242127072511119 |
| GO:0005977 | glycogen metabolic process | 0.0242127072511119 |
| GO:0006112 | energy reserve metabolic process | 0.0242127072511119 |
| GO:0016903 | oxidoreductase activity, acting on the aldehyde or oxo group of donors | 0.0242127072511119 |
| GO:0048037 | cofactor binding | 0.0242127072511119 |
| GO:0006091 | generation of precursor metabolites and energy | 0.0242127072511119 |
| GO:0004608 | phosphatidylethanolamine N-methyltransferase activity | 0.0242127072511119 |
| GO:0051156 | glucose 6-phosphate metabolic process | 0.0242127072511119 |
| GO:0004491 | methylmalonate-semialdehyde dehydrogenase (acylating) activity | 0.0242127072511119 |
| GO:0046415 | urate metabolic process | 0.0242127072511119 |
| GO:0001977 | renal regulation of blood volume | 0.0242127072511119 |
| GO:0002017 | aldosterone mediated regulation of blood volume | 0.0242127072511119 |
| GO:0004494 | methylmalonyl-CoA mutase activity | 0.0242127072511119 |
| GO:0004507 | steroid 11-beta-monooxygenase activity | 0.0242127072511119 |
| GO:0006307 | DNA dealkylation | 0.0242127072511119 |
| GO:0006705 | mineralocorticoid biosynthetic process | 0.0242127072511119 |
| GO:0032342 | aldosterone biosynthetic process | 0.0242127072511119 |
| GO:0044264 | cellular polysaccharide metabolic process | 0.0254827065698553 |
| GO:0005976 | polysaccharide metabolic process | 0.0254827065698553 |
| GO:0032341 | aldosterone metabolic process | 0.0332742320185638 |
| GO:0003908 | methylated-DNA-[protein]-cysteine S-methyltransferase activity | 0.0332742320185638 |
| GO:0004607 | phosphatidylcholine-sterol O-acyltransferase activity | 0.0332742320185638 |
| GO:0008184 | glycogen phosphorylase activity | 0.0332742320185638 |
| GO:0008212 | mineralocorticoid metabolic process | 0.0332742320185638 |
| GO:0004346 | glucose-6-phosphatase activity | 0.0332742320185638 |
| GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity | 0.0332742320185638 |
| GO:0047783 | corticosterone 18-monooxygenase activity | 0.0332742320185638 |
| GO:0008610 | lipid biosynthetic process | 0.0335243363309589 |
| GO:0015980 | energy derivation by oxidation of organic compounds | 0.0342196772509301 |
| GO:0044275 | cellular carbohydrate catabolic process | 0.0342196772509301 |
| GO:0044262 | cellular carbohydrate metabolic process | 0.0353679485546969 |
| GO:0006066 | alcohol metabolic process | 0.0368177256429547 |
| GO:0016052 | carbohydrate catabolic process | 0.0374016203066091 |
| GO:0015760 | glucose-6-phosphate transport | 0.0399072050714338 |
| GO:0030976 | thiamin pyrophosphate binding | 0.0399072050714338 |
| GO:0005980 | glycogen catabolic process | 0.0472715222525254 |
| GO:0009251 | glucan catabolic process | 0.0472715222525254 |
| GO:0003071 | renal regulation of systemic arterial blood pressure | 0.0472715222525254 |
| GO:0004645 | phosphorylase activity | 0.0472715222525254 |
| GO:0003997 | acyl-CoA oxidase activity | 0.0472715222525254 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| metabolising cell | 8.85e-12 | 5 |
| endopolyploid cell | 8.85e-12 | 5 |
| parenchymal cell | 8.85e-12 | 5 |
| polyploid cell | 8.85e-12 | 5 |
| hepatocyte | 8.85e-12 | 5 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
{{{tfbs_overrepresentation_jaspar}}} |
