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MCL coexpression mm9:165

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:92798965..92798984,+p1@Gm17745
Mm9::chr11:103273968..103273980,-p2@Plekhm1
Mm9::chr11:77614793..77614823,+p3@Myo18a
Mm9::chr11:79337262..79337263,-p10@Evi2b
Mm9::chr13:49404567..49404583,-p5@Fgd3
Mm9::chr13:52678433..52678446,+p12@Syk
Mm9::chr13:52678451..52678492,+p4@Syk
Mm9::chr13:52678619..52678631,+p18@Syk
Mm9::chr13:52678701..52678720,+p14@Syk
Mm9::chr13:52678821..52678843,+p5@Syk
Mm9::chr13:52728696..52728706,+p@chr13:52728696..52728706
+
Mm9::chr14:33938461..33938465,-p@chr14:33938461..33938465
-
Mm9::chr14:33998675..33998743,-p1@Wdfy4
Mm9::chr14:51748714..51748725,+p4@Rnase6
Mm9::chr14:75629427..75629455,+p@chr14:75629427..75629455
+
Mm9::chr15:103284213..103284291,+p1@Nckap1l
Mm9::chr15:78075450..78075481,+p3@Ncf4
Mm9::chr17:36157473..36157515,-p1@H2-T24
p1@LOC100045444
Mm9::chr17:51133002..51133013,-p@chr17:51133002..51133013
-
Mm9::chr17:84247227..84247263,-p@chr17:84247227..84247263
-
Mm9::chr17:84580956..84580994,+p@chr17:84580956..84580994
+
Mm9::chr18:31919471..31919505,+p3@Ammecr1l
Mm9::chr19:10651929..10651951,+p1@Cybasc3
Mm9::chr19:10651971..10651982,+p2@Cybasc3
Mm9::chr19:4201591..4201623,-p1@Rad9
Mm9::chr1:130488861..130488884,-p1@Cxcr4
Mm9::chr1:154654957..154655006,+p1@Ncf2
Mm9::chr1:154655007..154655028,+p3@Ncf2
Mm9::chr1:157882522..157882561,+p5@Tor1aip2
Mm9::chr1:157883021..157883066,-p2@Tor1aip1
Mm9::chr1:37552967..37553001,-p4@Mgat4a
Mm9::chr1:58852215..58852291,+p1@Casp8
Mm9::chr1:89516909..89516976,+p1@Inpp5d
Mm9::chr2:112106551..112106561,+p11@Slc12a6
Mm9::chr2:112106613..112106661,+p6@Slc12a6
Mm9::chr2:118554262..118554280,-p5@Plcb2
Mm9::chr2:120230452..120230482,+p3@Ganc
Mm9::chr3:106592921..106592946,-p2@Cd53
Mm9::chr3:60276984..60277005,+p2@Mbnl1
Mm9::chr4:135451329..135451391,+p1@Cnr2
Mm9::chr4:3605224..3605249,+p2@Gm11787
p2@Lyn
Mm9::chr4:3605255..3605281,+p1@Gm11787
p1@Lyn
Mm9::chr5:122659857..122659923,+p1@Hvcn1
Mm9::chr5:86500759..86500781,+p1@Stap1
Mm9::chr6:124683039..124683050,-p6@Ptpn6
Mm9::chr6:145070358..145070366,+p7@Lrmp
Mm9::chr7:124524451..124524506,+p1@Xylt1
Mm9::chr7:133848036..133848056,-p4@Coro1a
Mm9::chr7:20163377..20163392,-p@chr7:20163377..20163392
-
Mm9::chr7:20163393..20163408,-p@chr7:20163393..20163408
-
Mm9::chr7:52490832..52490848,-p10@Cd37
Mm9::chr7:52494164..52494234,-p1@Cd37
Mm9::chr7:82846851..82846900,+p2@Akap13
Mm9::chr8:120022172..120022191,+p1@Plcg2
Mm9::chr8:120022193..120022218,+p2@Plcg2
Mm9::chr8:125394506..125394522,+p2@uc009ntw.1
Mm9::chr8:3353609..3353620,+p5@A430078G23Rik
Mm9::chr8:49033713..49033727,-p@chr8:49033713..49033727
-
Mm9::chr8:68992926..68992931,+p@chr8:68992926..68992931
+
Mm9::chr8:87225329..87225396,+p1@Lyl1
Mm9::chr9:32348943..32349001,-p1@Fli1
Mm9::chr9:57492932..57492943,-p5@Csk
Mm9::chr9:57492961..57492987,-p3@Csk
Mm9::chr9:57492995..57493014,-p2@Csk
Mm9::chrX:131090671..131090672,-p@chrX:131090671..131090672
-
Mm9::chrX:131117653..131117688,-p1@Btk
Mm9::chrX:83115560..83115590,+p2@5430427O19Rik


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0045579positive regulation of B cell differentiation0.0229382452089853
GO:0004715non-membrane spanning protein tyrosine kinase activity0.0229382452089853
GO:0007242intracellular signaling cascade0.025854791355854
GO:0045577regulation of B cell differentiation0.025854791355854
GO:0045621positive regulation of lymphocyte differentiation0.0357557661754232
GO:0032943mononuclear cell proliferation0.0357557661754232
GO:0046651lymphocyte proliferation0.0357557661754232
GO:0002376immune system process0.0357557661754232
GO:0046649lymphocyte activation0.0357557661754232
GO:0051249regulation of lymphocyte activation0.0357557661754232
GO:0005737cytoplasm0.0357557661754232
GO:0050865regulation of cell activation0.0357557661754232
GO:0045321leukocyte activation0.0357557661754232
GO:0030097hemopoiesis0.0357557661754232
GO:0030099myeloid cell differentiation0.0357557661754232
GO:0045619regulation of lymphocyte differentiation0.0357557661754232
GO:0001775cell activation0.0357557661754232
GO:0050871positive regulation of B cell activation0.0357557661754232
GO:0048534hemopoietic or lymphoid organ development0.0357557661754232
GO:0002520immune system development0.0357557661754232
GO:0008375acetylglucosaminyltransferase activity0.0357557661754232
GO:0042110T cell activation0.0357557661754232
GO:0045588positive regulation of gamma-delta T cell differentiation0.0357557661754232
GO:0046643regulation of gamma-delta T cell activation0.0357557661754232
GO:003068690S preribosome0.0357557661754232
GO:0030690Noc1p-Noc2p complex0.0357557661754232
GO:0046645positive regulation of gamma-delta T cell activation0.0357557661754232
GO:0045659negative regulation of neutrophil differentiation0.0357557661754232
GO:0045586regulation of gamma-delta T cell differentiation0.0357557661754232
GO:0030171voltage-gated proton channel activity0.0357557661754232
GO:0045658regulation of neutrophil differentiation0.0357557661754232
GO:0005521lamin binding0.0357557661754232
GO:0030852regulation of granulocyte differentiation0.0357557661754232
GO:0030687nucleolar preribosome, large subunit precursor0.0357557661754232
GO:0030853negative regulation of granulocyte differentiation0.0357557661754232
GO:0045409negative regulation of interleukin-6 biosynthetic process0.0357557661754232
GO:00003343-hydroxyanthranilate 3,4-dioxygenase activity0.0357557661754232
GO:0030689Noc complex0.0357557661754232
GO:0045656negative regulation of monocyte differentiation0.0357557661754232
GO:0045655regulation of monocyte differentiation0.0357557661754232
GO:0002521leukocyte differentiation0.0389229665753655
GO:0030183B cell differentiation0.0393318142679435
GO:0050864regulation of B cell activation0.0428888017035016
GO:0002573myeloid leukocyte differentiation0.0488960027584729



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
hemolymphoid system6.27e-1648
immune system6.27e-1648
hematopoietic system2.66e-1445
blood island2.66e-1445
bone marrow3.30e-1016
lateral plate mesoderm2.11e-0987
bone element2.33e-0922
skeletal element2.33e-0922
skeletal system2.33e-0922
musculoskeletal system7.03e-0832
mesoderm9.07e-08120
mesoderm-derived structure9.07e-08120
presumptive mesoderm9.07e-08120


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.428189
MA0004.11.3765
MA0006.10.0204236
MA0007.10.429024
MA0009.10.46576
MA0014.10.110813
MA0017.10.618636
MA0019.10.242182
MA0024.10.406955
MA0025.10.303494
MA0027.11.59941
MA0028.10.232316
MA0029.10.378863
MA0030.10.775333
MA0031.10.698051
MA0038.10.0344662
MA0040.10.483091
MA0041.10.459147
MA0042.10.627755
MA0043.10.210566
MA0046.10.173584
MA0048.10.264607
MA0050.11.61234
MA0051.11.83759
MA0052.10.494368
MA0055.10.425442
MA0056.10
MA0057.10.0931481
MA0058.11.45372
MA0059.10.908658
MA0060.10.133231
MA0061.10.198226
MA0063.10
MA0066.11.27728
MA0067.10.387388
MA0068.10.0183569
MA0069.10.957425
MA0070.10.15943
MA0071.10.0663704
MA0072.10.154697
MA0073.10.0674022
MA0074.10.103106
MA0076.10.49367
MA0077.10.142892
MA0078.10.174236
MA0081.13.03047
MA0083.10.210065
MA0084.10.664822
MA0087.10.540362
MA0088.10.772187
MA0089.10
MA0090.10.379579
MA0091.10.0538249
MA0092.10.380367
MA0093.12.03412
MA0095.10
MA0098.10
MA0100.10.0218536
MA0101.10.15393
MA0103.10.463373
MA0105.11.70035
MA0106.10.181356
MA0107.10.0321896
MA0108.20.564254
MA0109.10
MA0111.10.112742
MA0113.10.643071
MA0114.10.0079246
MA0115.10.212338
MA0116.10.702222
MA0117.10.192271
MA0119.10.465068
MA0122.10.590697
MA0124.10.346379
MA0125.10.793271
MA0130.10
MA0131.10.237396
MA0132.10
MA0133.10
MA0135.10.234087
MA0136.13.21928
MA0139.10.458262
MA0140.10.23639
MA0141.10.0132779
MA0142.10.324979
MA0143.10.0446173
MA0144.10.059114
MA0145.10.598136
MA0146.10.257985
MA0147.10.357038
MA0148.10.783122
MA0149.10.161517
MA0062.21.51971
MA0035.21.08834
MA0039.20.718715
MA0138.20.0641537
MA0002.20.0846659
MA0137.20.202977
MA0104.20.180336
MA0047.20.322259
MA0112.21.06301
MA0065.20.0613493
MA0150.10.245658
MA0151.10
MA0152.10.322429
MA0153.10.245148
MA0154.10.919861
MA0155.10.376483
MA0156.13.6481
MA0157.10.0847892
MA0158.10
MA0159.10.564224
MA0160.10.308291
MA0161.10
MA0162.10.00101833
MA0163.10.145337
MA0164.10.282353
MA0080.28.5371
MA0018.20.124921
MA0099.20.48382
MA0079.20.274013
MA0102.21.69511
MA0258.10.387656
MA0259.10.0260127
MA0442.10
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