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|ontology_enrichment_disease=
|ontology_enrichment_disease=
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|ontology_enrichment_uberon=UBERON:0000475!8.59e-16!365;UBERON:0000481!4.68e-10!347;UBERON:0000119!1.63e-09!312;UBERON:0003102!1.97e-09!95;UBERON:0000914!2.72e-09!83;UBERON:0002329!2.72e-09!83;UBERON:0003077!2.72e-09!83;UBERON:0003059!2.72e-09!83;UBERON:0007282!2.72e-09!83;UBERON:0009618!2.72e-09!83;UBERON:0007285!2.72e-09!83;UBERON:0000483!3.88e-09!309;UBERON:0000468!3.14e-08!659;UBERON:0000486!4.07e-08!82;UBERON:0000477!7.77e-08!286;UBERON:0004290!9.51e-08!70;UBERON:0000033!1.85e-07!123;UBERON:0002097!4.27e-07!40;UBERON:0000153!4.97e-07!129;UBERON:0007811!4.97e-07!129;UBERON:0000467!6.49e-07!625;UBERON:0002199!6.62e-07!45;UBERON:0002416!6.62e-07!45;UBERON:0001134!7.60e-07!61;UBERON:0002036!7.60e-07!61;UBERON:0003082!7.60e-07!61;UBERON:0002385!8.81e-07!63;UBERON:0001015!8.81e-07!63;UBERON:0000383!8.81e-07!63;UBERON:0000480!9.34e-07!626
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}}
}}

Revision as of 18:54, 8 August 2012


Full id: C3103_Fibroblast_prostate_Olfactory_Smooth_meningioma_Preadipocyte_Myoblast



Phase1 CAGE Peaks

Hg19::chr11:122018727..122018742,-p@chr11:122018727..122018742
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Hg19::chr11:122018961..122018971,-p@chr11:122018961..122018971
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Hg19::chr11:122022942..122022947,-p1@MIR100


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell2.64e-25180
fibroblast3.02e-2075
skin fibroblast1.10e-1123
muscle precursor cell1.68e-0757
myoblast1.68e-0757
multi-potent skeletal muscle stem cell1.68e-0757
Uber Anatomy
Ontology termp-valuen
organism subdivision8.59e-16365
multi-tissue structure4.68e-10347
cell layer1.63e-09312
surface structure1.97e-0995
somite2.72e-0983
paraxial mesoderm2.72e-0983
presomitic mesoderm2.72e-0983
presumptive segmental plate2.72e-0983
trunk paraxial mesoderm2.72e-0983
presumptive paraxial mesoderm2.72e-0983
epithelium3.88e-09309
multi-cellular organism3.14e-08659
multilaminar epithelium4.07e-0882
anatomical cluster7.77e-08286
dermomyotome9.51e-0870
head1.85e-07123
skin of body4.27e-0740
anterior region of body4.97e-07129
craniocervical region4.97e-07129
anatomical system6.49e-07625
integument6.62e-0745
integumental system6.62e-0745
skeletal muscle tissue7.60e-0761
striated muscle tissue7.60e-0761
myotome7.60e-0761
muscle tissue8.81e-0763
musculature8.81e-0763
musculature of body8.81e-0763
anatomical group9.34e-07626


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.