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CL:0000115

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Name:endothelial cell
Namespace:FANTOM
Definition:"An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://63.198.234.228/OpenFMA/Endothelial%20cell.html, https://sourceforge.net/tracker/?func
Xrefs:
links:

BTO:0001176

FMA:66772
Synonyms: "endotheliocyte" EXACT []
Comments:From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000213(lining cell),CL:0002078(meso-epithelial cell)



Children


is a:CL:0002139 (endothelial cell of vascular tree),CL:0002188 (glomerular endothelial cell),CL:0002262 (endothelial cell of sinusoid),CL:0002367 (trabecular meshwork cell),FF:13595-146E4 (liver sinusoidal endothelial cells, sham operation, biol_rep1),FF:13596-146E5 (liver sinusoidal endothelial cells, sham operation, biol_rep2),FF:13597-146E6 (liver sinusoidal endothelial cells, sham operation, biol_rep3),FF:13598-146E7 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep1),FF:13599-146E8 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep2),FF:13600-146E9 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep3),FF:13601-146F1 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep1),FF:13602-146F2 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep2),FF:13603-146F3 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep3),FF:13604-146F4 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep1),FF:13605-146F5 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep2),FF:13606-146F6 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep3),FF:13607-146F7 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep1),FF:13608-146F8 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep2),FF:13609-146F9 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep3)
derives from:FF:0000046 (human endothelial cell sample)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000115 (endothelial cell), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
9.88e-148FFCP PHASE2:Hg19::chr6:3753188..3753192,-#_06bc30e74497af619d61975e77d8eb98p@chr6:3753188..3753192, -
9.88e-148FFCP PHASE1:Hg19::chr6:3753188..3753192,-#_06bc30e74497af619d61975e77d8eb98p@chr6:3753188..3753192, -
1.61e-140FFCP PHASE2:Hg19::chr2:56216687..56216727,-#_fab41e54c2e336d47c48c7d6dee52670p1@MIR216A
1.61e-140FFCP PHASE1:Hg19::chr2:56216687..56216727,-#_fab41e54c2e336d47c48c7d6dee52670p1@MIR216A
6.06e-136FFCP PHASE2:Hg19::chr17:62084108..62084111,-#_9a0069514c9294f599f7e5cc7fbf874bp5@ICAM2
6.06e-136FFCP PHASE1:Hg19::chr17:62084108..62084111,-#_9a0069514c9294f599f7e5cc7fbf874bp5@ICAM2
9.36e-136FFCP PHASE1:Hg19::chr11:124761247..124761258,-#_85f7ac7e0263a7f05e6cc84e9456b9d2p@chr11:124761247..124761258, -
9.36e-136FFCP PHASE2:Hg19::chr11:124761247..124761258,-#_85f7ac7e0263a7f05e6cc84e9456b9d2p@chr11:124761247..124761258, -
8.29e-123FFCP PHASE1:Hg19::chr16:2220383..2220402,+#_0a24232b2879c978fc4e9db6fa2d5b69p@chr16:2220383..2220402, +
8.29e-123FFCP PHASE2:Hg19::chr16:2220383..2220402,+#_0a24232b2879c978fc4e9db6fa2d5b69+, p@chr16:2220383..2220402
7.69e-118FFCP PHASE2:Hg19::chrX:71299684..71299699,+#_9b523ba8e131c3ff26b28cd1106422ccp@chrX:71299684..71299699, +
7.69e-118FFCP PHASE1:Hg19::chrX:71299684..71299699,+#_9b523ba8e131c3ff26b28cd1106422ccp@chrX:71299684..71299699, +
8.89e-118FFCP PHASE2:Hg19::chr5:95920642..95920681,+#_21ce1d641a2177218ecff1a2973dc1c5p1@ENST00000513158
8.89e-118FFCP PHASE1:Hg19::chr5:95920642..95920681,+#_21ce1d641a2177218ecff1a2973dc1c5p1@ENST00000513158
2.23e-117FFCP PHASE1:Hg19::chr13:32835894..32835907,+#_785c732e886f06e401cd15af7c92f860p@chr13:32835894..32835907, +
2.23e-117FFCP PHASE2:Hg19::chr13:32835894..32835907,+#_785c732e886f06e401cd15af7c92f860p@chr13:32835894..32835907, +
3.21e-114FFCP PHASE2:Hg19::chr18:33047117..33047138,-#_381dcad6998a74e5410f9a824c731022p@chr18:33047117..33047138, -
3.21e-114FFCP PHASE1:Hg19::chr18:33047117..33047138,-#_381dcad6998a74e5410f9a824c731022p@chr18:33047117..33047138, -
5.66e-114FFCP PHASE1:Hg19::chr15:39423060..39423066,+#_9bcfe4f795a9e4c53d755f86ed810026p@chr15:39423060..39423066, +
5.66e-114FFCP PHASE2:Hg19::chr15:39423060..39423066,+#_9bcfe4f795a9e4c53d755f86ed810026p@chr15:39423060..39423066, +
5.52e-113FFCP PHASE1:Hg19::chr18:33046982..33046991,-#_684b3e4bb6885f0a1d1b627d7f2e3c99p@chr18:33046982..33046991, -
5.52e-113FFCP PHASE2:Hg19::chr18:33046982..33046991,-#_684b3e4bb6885f0a1d1b627d7f2e3c99p@chr18:33046982..33046991, -
4.6e-112FFCP PHASE1:Hg19::chrX:15518894..15518905,+#_16f64d24281979e3f09e9ffb7a1ff9b0p2@BMX
4.6e-112FFCP PHASE2:Hg19::chrX:15518894..15518905,+#_16f64d24281979e3f09e9ffb7a1ff9b0p2@BMX
2.66e-111FFCP PHASE2:Hg19::chr12:105863654..105863682,+#_25731f1147645a59858d91acc0ec7a96+, p@chr12:105863654..105863682
2.66e-111FFCP PHASE1:Hg19::chr12:105863654..105863682,+#_25731f1147645a59858d91acc0ec7a96p@chr12:105863654..105863682, +
1.63e-110FFCP PHASE1:Hg19::chr14:38725249..38725254,-#_e37384ebfd73de880ebb5562b9abcbcdp6@CLEC14A
1.63e-110FFCP PHASE2:Hg19::chr14:38725249..38725254,-#_e37384ebfd73de880ebb5562b9abcbcdp6@CLEC14A
7.97e-110FFCP PHASE1:Hg19::chr14:38725228..38725236,-#_a8b40fb330c1d3e81fba7f2f8ed0876bp5@CLEC14A
7.97e-110FFCP PHASE2:Hg19::chr14:38725228..38725236,-#_a8b40fb330c1d3e81fba7f2f8ed0876bp5@CLEC14A
6.56e-109FFCP PHASE2:Hg19::chr18:33047157..33047168,-#_6b2dc6ff68fb7578d5809bc92e1707c1p@chr18:33047157..33047168, -
6.56e-109FFCP PHASE1:Hg19::chr18:33047157..33047168,-#_6b2dc6ff68fb7578d5809bc92e1707c1p@chr18:33047157..33047168, -
7.47e-109FFCP PHASE2:Hg19::chr12:105863636..105863650,+#_8ad218010ff3980fae406f8e73352966p@chr12:105863636..105863650, +
7.47e-109FFCP PHASE1:Hg19::chr12:105863636..105863650,+#_8ad218010ff3980fae406f8e73352966p@chr12:105863636..105863650, +
1.87e-108FFCP PHASE2:Hg19::chr3:43538305..43538325,-#_66692a06d918de47eff75e48ef7cf4d1p@chr3:43538305..43538325, -
1.87e-108FFCP PHASE1:Hg19::chr3:43538305..43538325,-#_66692a06d918de47eff75e48ef7cf4d1p@chr3:43538305..43538325, -
1.97e-108FFCP PHASE1:Hg19::chr10:129785574..129785580,+#_f65ae4b4706cd3cd3f7135eedd961d5bp14@PTPRE
1.97e-108FFCP PHASE2:Hg19::chr10:129785574..129785580,+#_f65ae4b4706cd3cd3f7135eedd961d5bp14@PTPRE
2.37e-108FFCP PHASE2:Hg19::chr9:139543390..139543404,+#_246a11e56064fdca30885871771165afp@chr9:139543390..139543404, +
2.37e-108FFCP PHASE1:Hg19::chr9:139543390..139543404,+#_246a11e56064fdca30885871771165afp@chr9:139543390..139543404, +
9.99e-107FFCP PHASE1:Hg19::chr19:4639579..4639589,+#_07c5ca06b169e93ec9904b869098b483p2@TNFAIP8L1
9.99e-107FFCP PHASE2:Hg19::chr19:4639579..4639589,+#_07c5ca06b169e93ec9904b869098b483p2@TNFAIP8L1
5.19e-104FFCP PHASE2:Hg19::chr13:32835912..32835936,+#_a7d084e376072fc3d27dae6989cd2181p@chr13:32835912..32835936, +
5.19e-104FFCP PHASE1:Hg19::chr13:32835912..32835936,+#_a7d084e376072fc3d27dae6989cd2181p@chr13:32835912..32835936, +
8.89e-103FFCP PHASE2:Hg19::chr13:32838801..32838818,+#_e6d1da271bb41cc6b46da58bd6f8048ap9@FRY
8.89e-103FFCP PHASE1:Hg19::chr13:32838801..32838818,+#_e6d1da271bb41cc6b46da58bd6f8048ap9@FRY
3.87e-101FFCP PHASE2:Hg19::chr17:47287786..47287797,+#_beaba73ecc618e5758f5218112744586p4@ABI3
3.87e-101FFCP PHASE1:Hg19::chr17:47287786..47287797,+#_beaba73ecc618e5758f5218112744586p4@ABI3
1.92e-100FFCP PHASE1:Hg19::chr19:41985048..41985050,-#_c61c32af69712cdc8ae290920468e219p@chr19:41985048..41985050, -
1.92e-100FFCP PHASE2:Hg19::chr19:41985048..41985050,-#_c61c32af69712cdc8ae290920468e219p@chr19:41985048..41985050, -
9.53e-100FFCP PHASE2:Hg19::chr16:66413317..66413328,+#_de3d3861818eb9acef73a3d5a70e3250p1@AB385138
9.53e-100FFCP PHASE1:Hg19::chr16:66413317..66413328,+#_de3d3861818eb9acef73a3d5a70e3250p1@AB385138
9.54e-99FFCP PHASE1:Hg19::chr12:118112251..118112272,-#_6aa08e6bfd1d85a8e73a8f040411daebp12@KSR2
9.54e-99FFCP PHASE2:Hg19::chr12:118112251..118112272,-#_6aa08e6bfd1d85a8e73a8f040411daebp12@KSR2
2.11e-98FFCP PHASE2:Hg19::chr7:150329732..150329739,-#_5f3978443f6c36d83318fdb322df882fp8@GIMAP6
2.11e-98FFCP PHASE1:Hg19::chr7:150329732..150329739,-#_5f3978443f6c36d83318fdb322df882fp8@GIMAP6
1.26e-97FFCP PHASE2:Hg19::chr5:176433333..176433349,-#_ec81fa9cd193f97b0802ecbb0f1e2d93p11@UIMC1
1.26e-97FFCP PHASE1:Hg19::chr5:176433333..176433349,-#_ec81fa9cd193f97b0802ecbb0f1e2d93p11@UIMC1
4.26e-97FFCP PHASE1:Hg19::chr10:50153735..50153750,+#_f9bc43df97004d7f744aa7deee63561cp6@WDFY4
4.26e-97FFCP PHASE2:Hg19::chr10:50153735..50153750,+#_f9bc43df97004d7f744aa7deee63561cp6@WDFY4
5.01e-97FFCP PHASE1:Hg19::chr12:105863705..105863718,+#_6539287d81ebfcfefb27a97039d4d2d8p@chr12:105863705..105863718, +
5.01e-97FFCP PHASE2:Hg19::chr12:105863705..105863718,+#_6539287d81ebfcfefb27a97039d4d2d8p@chr12:105863705..105863718, +
3.98e-96FFCP PHASE1:Hg19::chr10:99655692..99655725,-#_51ba59a5683c8361aa6aa645b5701691p@chr10:99655692..99655725, -
3.98e-96FFCP PHASE2:Hg19::chr10:99655692..99655725,-#_51ba59a5683c8361aa6aa645b5701691p@chr10:99655692..99655725, -
8.76e-96FFCP PHASE1:Hg19::chr11:124767798..124767809,-#_68fa61fd333ba639cb688dc6931ca6c1p3@ROBO4
8.76e-96FFCP PHASE2:Hg19::chr11:124767798..124767809,-#_68fa61fd333ba639cb688dc6931ca6c1p3@ROBO4
1.94e-95FFCP PHASE1:Hg19::chr12:80084018..80084035,-#_64578b003dc87499ed0c1e19f3483119p17@PAWR
1.94e-95FFCP PHASE2:Hg19::chr12:80084018..80084035,-#_64578b003dc87499ed0c1e19f3483119p17@PAWR
6.54e-95FFCP PHASE1:Hg19::chr17:75137460..75137485,+#_f0fa33f8112dd683b0eccd4b617b414ap@chr17:75137460..75137485, +
6.54e-95FFCP PHASE2:Hg19::chr17:75137460..75137485,+#_f0fa33f8112dd683b0eccd4b617b414ap@chr17:75137460..75137485, +
1.27e-94FFCP PHASE2:Hg19::chr6:132455180..132455197,+#_ccf5128a2e6e14689f6343d2310460fcp2@LOC100507254
1.27e-94FFCP PHASE1:Hg19::chr6:132455180..132455197,+#_ccf5128a2e6e14689f6343d2310460fcp2@LOC100507254
1.3e-93FFCP PHASE2:Hg19::chr3:58034268..58034295,+#_65485d3061024adcf41fafa0db23adcdp@chr3:58034268..58034295, +
1.3e-93FFCP PHASE1:Hg19::chr3:58034268..58034295,+#_65485d3061024adcf41fafa0db23adcdp@chr3:58034268..58034295, +
1.98e-93FFCP PHASE2:Hg19::chr6:78171774..78171792,+#_90ab8e2a9b473a97de881613c2652f66p@chr6:78171774..78171792, +
1.98e-93FFCP PHASE1:Hg19::chr6:78171774..78171792,+#_90ab8e2a9b473a97de881613c2652f66p@chr6:78171774..78171792, +
1.01e-92FFCP PHASE1:Hg19::chr19:47220191..47220198,-#_56a3ccd9f872e025444523751eec91fep14@PRKD2
1.01e-92FFCP PHASE2:Hg19::chr19:47220191..47220198,-#_56a3ccd9f872e025444523751eec91fep14@PRKD2
1.93e-92FFCP PHASE2:Hg19::chr18:33047039..33047063,-#_b583652e47286b1cac8d3462d285a2fdp@chr18:33047039..33047063, -
1.93e-92FFCP PHASE1:Hg19::chr18:33047039..33047063,-#_b583652e47286b1cac8d3462d285a2fdp@chr18:33047039..33047063, -
2.0e-92FFCP PHASE1:Hg19::chr18:33047076..33047099,-#_0a111c3378aa97f5ed3ee9bf782840aep@chr18:33047076..33047099, -
2.0e-92FFCP PHASE1:Hg19::chr13:32838839..32838850,+#_0a111c3378aa97f5ed3ee9bf782840aep20@FRY
2.0e-92FFCP PHASE1:Hg19::chr7:139741594..139741615,-#_0a111c3378aa97f5ed3ee9bf782840aep5@PARP12
2.0e-92FFCP PHASE2:Hg19::chr13:32838839..32838850,+#_0a111c3378aa97f5ed3ee9bf782840aep20@FRY
2.0e-92FFCP PHASE2:Hg19::chr7:139741594..139741615,-#_0a111c3378aa97f5ed3ee9bf782840aep5@PARP12
2.0e-92FFCP PHASE2:Hg19::chr18:33047076..33047099,-#_0a111c3378aa97f5ed3ee9bf782840aep@chr18:33047076..33047099, -
6.65e-92FFCP PHASE2:Hg19::chr12:71031247..71031262,-#_4a40390335d2c543eefdf3784f1ff3dbp7@PTPRB
6.65e-92FFCP PHASE1:Hg19::chr12:71031247..71031262,-#_4a40390335d2c543eefdf3784f1ff3dbp7@PTPRB
1.75e-91FFCP PHASE2:Hg19::chr10:50153703..50153720,+#_6ca380c4836d4b130c90080dff551db7p7@WDFY4
1.75e-91FFCP PHASE1:Hg19::chr10:50153703..50153720,+#_6ca380c4836d4b130c90080dff551db7p7@WDFY4
2.48e-91FFCP PHASE2:Hg19::chr21:39869867..39869880,-#_b80cc45b9e6a64bf29bf6488c43165c0p@chr21:39869867..39869880, -
2.48e-91FFCP PHASE1:Hg19::chr21:39869867..39869880,-#_b80cc45b9e6a64bf29bf6488c43165c0p@chr21:39869867..39869880, -
5.09e-91FFCP PHASE2:Hg19::chr11:62344721..62344758,-#_8ca4b5923b1ca1721d461f978b2879d5p2@TUT1
5.09e-91FFCP PHASE1:Hg19::chr11:62344721..62344758,-#_8ca4b5923b1ca1721d461f978b2879d5p2@TUT1
1.11e-90FFCP PHASE2:Hg19::chr1:208063620..208063634,-#_931992a8819a1541b7815c9a4e82fbbap4@CD34
1.11e-90FFCP PHASE1:Hg19::chr1:208063620..208063634,-#_931992a8819a1541b7815c9a4e82fbbap4@CD34
1.26e-90FFCP PHASE1:Hg19::chr2:225266779..225266786,-#_97f6c73a7784fea0da7857c3c9bdd610p4@FAM124B
1.26e-90FFCP PHASE2:Hg19::chr2:225266779..225266786,-#_97f6c73a7784fea0da7857c3c9bdd610p4@FAM124B
2.6e-89FFCP PHASE1:Hg19::chr7:39663061..39663072,+#_36f5fa3e393cc28b9d225cc42eace732p6@RALA
2.6e-89FFCP PHASE2:Hg19::chr7:39663061..39663072,+#_36f5fa3e393cc28b9d225cc42eace732p6@RALA