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CL:0000556

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Name:megakaryocyte
Namespace:FANTOM
Definition:"A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm." [ISBN:0721601464, MESH:D008533]
Xrefs:
links:

BTO:0000843

FMA:83555
Synonyms: "megacaryocyte" EXACT []
"megalocaryocyte" EXACT []
"megalokaryocyte" EXACT []
Comments:Megakaryocytes are reportedly CD181-positive and CD182-positive.


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000763(myeloid cell),CL:1001610(bone marrow hematopoietic cell)
disjoint_from:CL:0000764(erythroid lineage cell)
develops_from:CL:0000553(megakaryocyte progenitor cell)
part_of:UBERON:0002371(bone marrow)



Children


is a:CL:0002027 (CD9-positive, CD41-positive megakaryocyte cell),FF:0101549 (megakaryocytic cell line)
derives from:FF:0011468 (mouse CD41-positive megakaryocyte control sample)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000556 (megakaryocyte), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
1.0e-60FFCP PHASE2:Mm9::chr3:40893940..40893948,+#_132d24c8283cc5b6b3f35dc48a6ea635+, p@chr3:40893940..40893948
1.0e-60FFCP PHASE1:Mm9::chr3:40893940..40893948,+#_132d24c8283cc5b6b3f35dc48a6ea635p@chr3:40893940..40893948, +
2.34e-60FFCP PHASE1:Mm9::chr6:68860437..68860451,-#_4de172110d26fb6f05c5730fb9b36d2bp@chr6:68860437..68860451, -
2.34e-60FFCP PHASE2:Mm9::chr6:68860437..68860451,-#_4de172110d26fb6f05c5730fb9b36d2bp@chr6:68860437..68860451, -
3.38e-58FFCP PHASE2:Mm9::chr3:41343162..41343165,+#_6276cfa83783bf14f4019d8d778be851p@chr3:41343162..41343165, +
3.38e-58FFCP PHASE1:Mm9::chr3:41343162..41343165,+#_6276cfa83783bf14f4019d8d778be851p@chr3:41343162..41343165, +
3.91e-58FFCP PHASE1:Mm9::chr9:108276696..108276698,+#_97a28ceb0d01d69a148eebcd1b8335edp@chr9:108276696..108276698, +
3.91e-58FFCP PHASE2:Mm9::chr9:108276696..108276698,+#_97a28ceb0d01d69a148eebcd1b8335edp@chr9:108276696..108276698, +
4.23e-58FFCP PHASE2:Mm9::chr2:98503916..98503926,+#_d12a87c03295df4e60e48e15760be08ep@chr2:98503916..98503926, +
4.23e-58FFCP PHASE1:Mm9::chr2:98503916..98503926,+#_d12a87c03295df4e60e48e15760be08ep@chr2:98503916..98503926, +
1.25e-52FFCP PHASE2:Mm9::chr4:105391511..105391533,+#_60133d19d1f9894e3150b53849eb6ac0p@chr4:105391511..105391533, +
1.25e-52FFCP PHASE1:Mm9::chr4:105391511..105391533,+#_60133d19d1f9894e3150b53849eb6ac0p@chr4:105391511..105391533, +
5.18e-52FFCP PHASE1:Mm9::chr6:69851116..69851126,-#_5836280e010abe51de02805818ef6143p2@ENSMUST00000103370
5.18e-52FFCP PHASE2:Mm9::chr6:69851116..69851126,-#_5836280e010abe51de02805818ef6143p2@ENSMUST00000103370
5.23e-52FFCP PHASE1:Mm9::chr10:41613773..41613784,+#_dc4da0847e0d408737c5f01d047476bcp@chr10:41613773..41613784, +
5.23e-52FFCP PHASE2:Mm9::chr17:34376620..34376634,-#_dc4da0847e0d408737c5f01d047476bcp@chr17:34376620..34376634, -
5.23e-52FFCP PHASE1:Mm9::chr17:34376620..34376634,-#_dc4da0847e0d408737c5f01d047476bcp@chr17:34376620..34376634, -
5.23e-52FFCP PHASE2:Mm9::chr10:41613773..41613784,+#_dc4da0847e0d408737c5f01d047476bcp@chr10:41613773..41613784, +
1.08e-51FFCP PHASE1:Mm9::chr9:32425275..32425296,+#_806205f44445fc0772d844b56de433c5p@chr9:32425275..32425296, +
1.08e-51FFCP PHASE2:Mm9::chr9:32425275..32425296,+#_806205f44445fc0772d844b56de433c5p@chr9:32425275..32425296, +
1.74e-51FFCP PHASE1:Mm9::chr6:70676952..70676959,-#_da8dbfc8b8d58c86276bcc876a70cce4p@chr6:70676952..70676959, -
1.74e-51FFCP PHASE2:Mm9::chr6:70676952..70676959,-#_da8dbfc8b8d58c86276bcc876a70cce4p@chr6:70676952..70676959, -
6.51e-48FFCP PHASE2:Mm9::chr17:88981299..88981314,+#_bb72f369134229df065775c6c748843ep@chr17:88981299..88981314, +
6.51e-48FFCP PHASE1:Mm9::chr17:88981299..88981314,+#_bb72f369134229df065775c6c748843ep@chr17:88981299..88981314, +
1.98e-47FFCP PHASE1:Mm9::chr12:48935035..48935049,+#_e55b0d3d02a3b90232a42454d7b446efp@chr12:48935035..48935049, +
1.98e-47FFCP PHASE2:Mm9::chr12:48935035..48935049,+#_e55b0d3d02a3b90232a42454d7b446efp@chr12:48935035..48935049, +
8.31e-47FFCP PHASE2:Mm9::chr11:96193855..96193860,+#_bd99f090b9006b92c58c2837f2556a08p@chr11:96193855..96193860, +
8.31e-47FFCP PHASE2:Mm9::chr13:30095274..30095283,+#_bd99f090b9006b92c58c2837f2556a08p@chr13:30095274..30095283, +
8.31e-47FFCP PHASE1:Mm9::chr13:30095274..30095283,+#_bd99f090b9006b92c58c2837f2556a08p@chr13:30095274..30095283, +
8.31e-47FFCP PHASE1:Mm9::chr11:96193855..96193860,+#_bd99f090b9006b92c58c2837f2556a08p@chr11:96193855..96193860, +
1.42e-46FFCP PHASE1:Mm9::chr19:11463663..11463671,+#_64b9247ee11c30216ffb56e2863f1452p@chr19:11463663..11463671, +
1.42e-46FFCP PHASE2:Mm9::chr19:11463663..11463671,+#_64b9247ee11c30216ffb56e2863f1452p@chr19:11463663..11463671, +
1.86e-46FFCP PHASE2:Mm9::chr3:58321410..58321423,+#_bd5194c89cfc4b2317e68e4edbd98248p@chr3:58321410..58321423, +
1.86e-46FFCP PHASE1:Mm9::chr3:58321410..58321423,+#_bd5194c89cfc4b2317e68e4edbd98248p@chr3:58321410..58321423, +
1.86e-46FFCP PHASE2:Mm9::chr13:112658212..112658227,+#_bd5194c89cfc4b2317e68e4edbd98248p3@ENSMUST00000128198, p3@uc007rwb.1
1.86e-46FFCP PHASE2:Mm9::chr17:34400036..34400056,-#_bd5194c89cfc4b2317e68e4edbd98248p@chr17:34400036..34400056, -
1.86e-46FFCP PHASE1:Mm9::chr17:34400036..34400056,-#_bd5194c89cfc4b2317e68e4edbd98248-, p@chr17:34400036..34400056
1.86e-46FFCP PHASE1:Mm9::chr13:112658212..112658227,+#_bd5194c89cfc4b2317e68e4edbd98248p3@ENSMUST00000128198, p3@uc007rwb.1
9.65e-46FFCP PHASE1:Mm9::chr4:135451095..135451110,+#_6b1521ffed2e7a974a5f9bba84a6681cp4@Cnr2
9.65e-46FFCP PHASE1:Mm9::chr16:19200368..19200390,-#_6b1521ffed2e7a974a5f9bba84a6681cp2@ENSMUST00000103749
9.65e-46FFCP PHASE2:Mm9::chr4:135451095..135451110,+#_6b1521ffed2e7a974a5f9bba84a6681cp4@Cnr2
9.65e-46FFCP PHASE2:Mm9::chr16:19200368..19200390,-#_6b1521ffed2e7a974a5f9bba84a6681cp2@ENSMUST00000103749
9.65e-46FFCP PHASE2:Mm9::chr12:114659326..114659343,-#_6b1521ffed2e7a974a5f9bba84a6681cp5@uc007pgs.1
9.65e-46FFCP PHASE2:Mm9::chr2:99640370..99640374,+#_6b1521ffed2e7a974a5f9bba84a6681cp@chr2:99640370..99640374, +
9.65e-46FFCP PHASE1:Mm9::chr12:114659326..114659343,-#_6b1521ffed2e7a974a5f9bba84a6681cp5@uc007pgs.1
9.65e-46FFCP PHASE1:Mm9::chr2:99640370..99640374,+#_6b1521ffed2e7a974a5f9bba84a6681cp@chr2:99640370..99640374, +
1.19e-45FFCP PHASE1:Mm9::chr12:100880892..100880902,-#_f183b4d80fd85f8f29c85f28e8e6d9f2p@chr12:100880892..100880902, -
1.19e-45FFCP PHASE2:Mm9::chr12:100880892..100880902,-#_f183b4d80fd85f8f29c85f28e8e6d9f2p@chr12:100880892..100880902, -
1.82e-45FFCP PHASE2:Mm9::chr9:32460050..32460070,+#_ab4936195bea033d3e87a618e969b62dp@chr9:32460050..32460070, +
1.82e-45FFCP PHASE1:Mm9::chr9:32460050..32460070,+#_ab4936195bea033d3e87a618e969b62dp@chr9:32460050..32460070, +
2.38e-44FFCP PHASE1:Mm9::chr12:114659633..114659652,-#_061cc06dc44941a2e4d346d9fffcee00p4@uc007pgs.1
2.38e-44FFCP PHASE1:Mm9::chr9:32487351..32487367,+#_061cc06dc44941a2e4d346d9fffcee00p@chr9:32487351..32487367, +
2.38e-44FFCP PHASE2:Mm9::chr9:32487351..32487367,+#_061cc06dc44941a2e4d346d9fffcee00+, p@chr9:32487351..32487367
2.38e-44FFCP PHASE2:Mm9::chr12:114659633..114659652,-#_061cc06dc44941a2e4d346d9fffcee00p4@uc007pgs.1
3.35e-44FFCP PHASE2:Mm9::chr5:122674421..122674426,+#_70bb9038eea536606c1aebb2a3c70200p@chr5:122674421..122674426, +
3.35e-44FFCP PHASE1:Mm9::chr5:122674421..122674426,+#_70bb9038eea536606c1aebb2a3c70200p@chr5:122674421..122674426, +
5.38e-44FFCP PHASE2:Mm9::chr4:44980637..44980644,+#_c5fe6b19031b9d643b5d4d24c6eee4dap4@ENSMUST00000150111
5.38e-44FFCP PHASE1:Mm9::chr4:44980637..44980644,+#_c5fe6b19031b9d643b5d4d24c6eee4dap4@ENSMUST00000150111
5.38e-44FFCP PHASE2:Mm9::chr18:35809146..35809153,-#_c5fe6b19031b9d643b5d4d24c6eee4dap4@2010001M09Rik
5.38e-44FFCP PHASE1:Mm9::chr4:59740918..59740923,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr4:59740918..59740923, +
5.38e-44FFCP PHASE1:Mm9::chr18:35809146..35809153,-#_c5fe6b19031b9d643b5d4d24c6eee4dap4@2010001M09Rik
5.38e-44FFCP PHASE2:Mm9::chr11:102210718..102210728,-#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr11:102210718..102210728, -
5.38e-44FFCP PHASE2:Mm9::chr4:59740918..59740923,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr4:59740918..59740923, +
5.38e-44FFCP PHASE2:Mm9::chr19:43721970..43721975,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr19:43721970..43721975, +
5.38e-44FFCP PHASE2:Mm9::chr6:135966781..135966785,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr6:135966781..135966785, +
5.38e-44FFCP PHASE2:Mm9::chr1:156964198..156964201,+#_c5fe6b19031b9d643b5d4d24c6eee4da+, p@chr1:156964198..156964201
5.38e-44FFCP PHASE2:Mm9::chr17:84975629..84975633,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr17:84975629..84975633, +
5.38e-44FFCP PHASE1:Mm9::chr19:43721970..43721975,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr19:43721970..43721975, +
5.38e-44FFCP PHASE1:Mm9::chr6:135966781..135966785,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr6:135966781..135966785, +
5.38e-44FFCP PHASE2:Mm9::chr18:55201820..55201826,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr18:55201820..55201826, +
5.38e-44FFCP PHASE1:Mm9::chr11:102210718..102210728,-#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr11:102210718..102210728, -
5.38e-44FFCP PHASE1:Mm9::chr18:55201820..55201826,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr18:55201820..55201826, +
5.38e-44FFCP PHASE1:Mm9::chr1:156964198..156964201,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr1:156964198..156964201, +
5.38e-44FFCP PHASE1:Mm9::chr17:84975629..84975633,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr17:84975629..84975633, +
6.62e-44FFCP PHASE1:Mm9::chr17:34282256..34282276,+#_ed19da4ea9561662f6188c4569255f28p4@H2-DMb2
6.62e-44FFCP PHASE2:Mm9::chr17:34282256..34282276,+#_ed19da4ea9561662f6188c4569255f28p4@H2-DMb2
2.83e-41FFCP PHASE2:Mm9::chr12:114660740..114660753,+#_8046e7040e1463913d9e7159d1373b19p@chr12:114660740..114660753, +
2.83e-41FFCP PHASE1:Mm9::chr12:114660740..114660753,+#_8046e7040e1463913d9e7159d1373b19p@chr12:114660740..114660753, +
4.64e-41FFCP PHASE2:Mm9::chr19:21705252..21705273,-#_f10ea5ba0408681ab8dca166a093cfecp@chr19:21705252..21705273, -
4.64e-41FFCP PHASE1:Mm9::chr19:21705252..21705273,-#_f10ea5ba0408681ab8dca166a093cfecp@chr19:21705252..21705273, -
7.27e-41FFCP PHASE1:Mm9::chr12:114652607..114652619,-#_13ee81766cdefd347a9bc92c6e28564bp@chr12:114652607..114652619, -
7.27e-41FFCP PHASE2:Mm9::chr12:114652607..114652619,-#_13ee81766cdefd347a9bc92c6e28564bp@chr12:114652607..114652619, -
8.77e-41FFCP PHASE2:Mm9::chr18:36069982..36069991,+#_c499b3f9377e6d5a84e26d85a1bf48cbp@chr18:36069982..36069991, +
8.77e-41FFCP PHASE1:Mm9::chr18:36069982..36069991,+#_c499b3f9377e6d5a84e26d85a1bf48cbp@chr18:36069982..36069991, +
8.77e-41FFCP PHASE2:Mm9::chr13:30095241..30095252,+#_c499b3f9377e6d5a84e26d85a1bf48cbp@chr13:30095241..30095252, +
8.77e-41FFCP PHASE1:Mm9::chr13:30095241..30095252,+#_c499b3f9377e6d5a84e26d85a1bf48cbp@chr13:30095241..30095252, +
1.02e-40FFCP PHASE1:Mm9::chr12:114659852..114659872,+#_5f20d10b5ad5102f68b6005d7c83e56cp@chr12:114659852..114659872, +
1.02e-40FFCP PHASE2:Mm9::chr12:114659852..114659872,+#_5f20d10b5ad5102f68b6005d7c83e56cp@chr12:114659852..114659872, +
1.02e-40FFCP PHASE1:Mm9::chr12:53180087..53180104,+#_5f20d10b5ad5102f68b6005d7c83e56cp@chr12:53180087..53180104, +
1.02e-40FFCP PHASE2:Mm9::chr12:53180087..53180104,+#_5f20d10b5ad5102f68b6005d7c83e56cp@chr12:53180087..53180104, +
1.06e-40FFCP PHASE1:Mm9::chr10:50076400..50076404,+#_854668bddbeddff362535dea3fda6c60p@chr10:50076400..50076404, +
1.06e-40FFCP PHASE2:Mm9::chr10:50076400..50076404,+#_854668bddbeddff362535dea3fda6c60p@chr10:50076400..50076404, +
1.91e-40FFCP PHASE2:Mm9::chr8:70480444..70480457,+#_1c16f61964ad512940b63478061a8184p2@ENSMUST00000127631
1.91e-40FFCP PHASE1:Mm9::chr8:70480444..70480457,+#_1c16f61964ad512940b63478061a8184p2@ENSMUST00000127631
4.18e-40FFCP PHASE1:Mm9::chr6:70676615..70676621,+#_b91c8a72a0995fdee99107017da9aefb+, p@chr6:70676615..70676621
4.18e-40FFCP PHASE2:Mm9::chr6:70676615..70676621,+#_b91c8a72a0995fdee99107017da9aefbp@chr6:70676615..70676621, +
2.4e-39FFCP PHASE1:Mm9::chr12:100880924..100880933,-#_7b507ef6159f077b542d577826c06d87p@chr12:100880924..100880933, -
2.4e-39FFCP PHASE2:Mm9::chr1:134238914..134238921,+#_7b507ef6159f077b542d577826c06d87p@chr1:134238914..134238921, +
2.4e-39FFCP PHASE1:Mm9::chr1:134238914..134238921,+#_7b507ef6159f077b542d577826c06d87p@chr1:134238914..134238921, +
2.4e-39FFCP PHASE2:Mm9::chr12:100880924..100880933,-#_7b507ef6159f077b542d577826c06d87p@chr12:100880924..100880933, -