Personal tools

CL:0000895

From FANTOM5_SSTAR

Jump to: navigation, search
Name:naive thymus-derived CD4-positive, alpha-beta T cell
Namespace:FANTOM
Definition:"An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low." [GO_REF:0000031, GOC:add, GOC:tfm, http://www.immgen.org/index_content.html, PMID:19100699]
Synonyms: "naive thymus-derived CD4-positive, alpha-beta T lymphocyte" EXACT []
"naive thymus-derived CD4-positive, alpha-beta T-cell" EXACT []
"naive thymus-derived CD4-positive, alpha-beta T-lymphocyte" EXACT []
"T.4Nve.Sp" EXACT []
"Th0" EXACT [GOC:tfm]
Comments:These cells have not been exposed to antigen following thymic T-cell selection; found in blood and secondary lymphoid organs.


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000624(CD4-positive, alpha-beta T cell),CL:0000898(naive T cell)
develops_from:CL:0002436(mature CD4 single-positive thymocyte)



Children


is a:FF:0011121 (CD4-positiveCD25-CD45RA- naive conventional T cells expanded)
derives from:FF:0011122 (human CD4-positiveCD25-CD45RA- naive conventional T cells sample),FF:0011446 (CD4-positiveCD25-CD44- naive conventional T cells stimulated with alphaCD3_CD28 - 06hr- (C57BL_6J) sample),FF:0011447 (CD4-positiveCD25-CD44- naive conventional T cells stimulated with alphaCD3_CD28- 06hr- (Balb_cAJcl) sample),FF:0011448 (CD4-positiveCD25-CD44- naive conventional T cells stimulated with PMA an ionomycin- 02hr- (C57BL_6J) sample),FF:0011449 (CD4-positiveCD25-CD44- naive conventional T cells stimulated with PMA an ionomycin- 02hr- (Balb_cAJcl) sample),FF:0011450 (CD4-positiveCD25-CD44- naive conventional T cells- (C57BL_6J) sample),FF:0011451 (CD4-positiveCD25-CD44- naive conventional T cells- (Balb_cAJcl) sample)
develops from:CL:0000896 (activated CD4-positive, alpha-beta T cell)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

  • 11786-124B4 (CD4+CD25-CD45RA- memory conventional T cells, donor1)
  • 11813-124E4 (CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J))
  • 11815-124E6 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J))
  • 11816-124E7 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J))
  • 11817-124E8 (CD4+CD25-CD44- naive conventional T cells, pool2 (Balb_cAJcl))
  • 11819-124F1 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool2 (Balb_cAJcl))
  • 11820-124F2 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool2 (Balb_cAJcl))

Mouse (Mus musculus)

  • 11786-124B4 (CD4+CD25-CD45RA- memory conventional T cells, donor1)
  • 11813-124E4 (CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J))
  • 11815-124E6 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J))
  • 11816-124E7 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J))
  • 11817-124E8 (CD4+CD25-CD44- naive conventional T cells, pool2 (Balb_cAJcl))
  • 11819-124F1 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool2 (Balb_cAJcl))
  • 11820-124F2 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool2 (Balb_cAJcl))


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000895 (naive thymus-derived CD4-positive, alpha-beta T cell), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
2.55e-98FFCP PHASE1:Hg19::chr1:183622379..183622388,-#_877754c48acaca1e7030c3a2c21c7e1ap4@APOBEC4
2.55e-98FFCP PHASE2:Hg19::chr2:162762361..162762364,+#_877754c48acaca1e7030c3a2c21c7e1ap@chr2:162762361..162762364, +
2.55e-98FFCP PHASE1:Hg19::chr2:162762361..162762364,+#_877754c48acaca1e7030c3a2c21c7e1ap@chr2:162762361..162762364, +
2.55e-98FFCP PHASE2:Hg19::chr1:183622379..183622388,-#_877754c48acaca1e7030c3a2c21c7e1ap4@APOBEC4
1.36e-86FFCP PHASE1:Mm9::chr13:30878406..30878419,+#_9e0e8d34b07ae1f0090f8f00ee7bd19ep@chr13:30878406..30878419, +
1.36e-86FFCP PHASE2:Mm9::chr13:30878406..30878419,+#_9e0e8d34b07ae1f0090f8f00ee7bd19ep@chr13:30878406..30878419, +
1.36e-86FFCP PHASE2:Mm9::chrX:54476786..54476810,+#_9e0e8d34b07ae1f0090f8f00ee7bd19ep@chrX:54476786..54476810, +
1.36e-86FFCP PHASE1:Mm9::chrX:54476786..54476810,+#_9e0e8d34b07ae1f0090f8f00ee7bd19ep@chrX:54476786..54476810, +
1.01e-74FFCP PHASE1:Mm9::chr16:52032670..52032685,+#_3b47b1952960f83420c988c97dc8eee9p@chr16:52032670..52032685, +
1.01e-74FFCP PHASE2:Mm9::chr16:52032670..52032685,+#_3b47b1952960f83420c988c97dc8eee9p@chr16:52032670..52032685, +
2.41e-74FFCP PHASE2:Mm9::chr16:93777453..93777464,+#_d298ad28011d96b8f5a9d9736e792fb1p@chr16:93777453..93777464, +
2.41e-74FFCP PHASE2:Mm9::chr14:54795946..54795960,+#_d298ad28011d96b8f5a9d9736e792fb1p1@ENSMUST00000103701
2.41e-74FFCP PHASE1:Mm9::chr14:54795946..54795960,+#_d298ad28011d96b8f5a9d9736e792fb1p1@ENSMUST00000103701
2.41e-74FFCP PHASE1:Mm9::chr16:93777453..93777464,+#_d298ad28011d96b8f5a9d9736e792fb1p@chr16:93777453..93777464, +
2.48e-72FFCP PHASE1:Mm9::chr11:11587720..11587735,+#_94832edd9377246242c59c524a406cfdp@chr11:11587720..11587735, +
2.48e-72FFCP PHASE1:Mm9::chr14:122362270..122362291,-#_94832edd9377246242c59c524a406cfdp@chr14:122362270..122362291, -
2.48e-72FFCP PHASE2:Mm9::chr14:122362270..122362291,-#_94832edd9377246242c59c524a406cfdp@chr14:122362270..122362291, -
2.48e-72FFCP PHASE1:Mm9::chr13:30853488..30853499,+#_94832edd9377246242c59c524a406cfdp@chr13:30853488..30853499, +
2.48e-72FFCP PHASE2:Mm9::chr14:54827490..54827502,+#_94832edd9377246242c59c524a406cfdp@chr14:54827490..54827502, +
2.48e-72FFCP PHASE2:Mm9::chr11:11587720..11587735,+#_94832edd9377246242c59c524a406cfdp@chr11:11587720..11587735, +
2.48e-72FFCP PHASE2:Mm9::chr15:80403112..80403122,+#_94832edd9377246242c59c524a406cfdp12@Grap2
2.48e-72FFCP PHASE1:Mm9::chr11:11592840..11592849,+#_94832edd9377246242c59c524a406cfdp@chr11:11592840..11592849, +
2.48e-72FFCP PHASE1:Mm9::chr15:80403112..80403122,+#_94832edd9377246242c59c524a406cfdp12@Grap2
2.48e-72FFCP PHASE2:Mm9::chr11:11592840..11592849,+#_94832edd9377246242c59c524a406cfdp@chr11:11592840..11592849, +
2.48e-72FFCP PHASE1:Mm9::chr14:54827490..54827502,+#_94832edd9377246242c59c524a406cfdp@chr14:54827490..54827502, +
2.48e-72FFCP PHASE2:Mm9::chr13:30853488..30853499,+#_94832edd9377246242c59c524a406cfdp@chr13:30853488..30853499, +
2.39e-66FFCP PHASE1:Hg19::chr9:75772924..75772957,+#_04189a82afa14ff6adf1929c0056182bp17@ANXA1
2.39e-66FFCP PHASE2:Hg19::chr9:75772924..75772957,+#_04189a82afa14ff6adf1929c0056182bp17@ANXA1
4.66e-66FFCP PHASE2:Hg19::chr11:118209514..118209525,+#_6ac0e645f7a64d9e69dba8f3b8760cabp@chr11:118209514..118209525, +
4.66e-66FFCP PHASE1:Hg19::chr2:204816181..204816219,-#_6ac0e645f7a64d9e69dba8f3b8760cab-, p@chr2:204816181..204816219
4.66e-66FFCP PHASE1:Hg19::chr11:118209514..118209525,+#_6ac0e645f7a64d9e69dba8f3b8760cabp@chr11:118209514..118209525, +
4.66e-66FFCP PHASE1:Hg19::chr20:37493438..37493456,-#_6ac0e645f7a64d9e69dba8f3b8760cabp@chr20:37493438..37493456, -
4.66e-66FFCP PHASE2:Hg19::chr2:204816181..204816219,-#_6ac0e645f7a64d9e69dba8f3b8760cabp@chr2:204816181..204816219, -
4.66e-66FFCP PHASE2:Hg19::chr20:37493438..37493456,-#_6ac0e645f7a64d9e69dba8f3b8760cabp@chr20:37493438..37493456, -
1.05e-65FFCP PHASE2:Mm9::chr14:53242248..53242261,+#_8004f2ea89e796c2fb960a433bf52178p@chr14:53242248..53242261, +
1.05e-65FFCP PHASE1:Mm9::chr14:53242248..53242261,+#_8004f2ea89e796c2fb960a433bf52178p@chr14:53242248..53242261, +
1.74e-65FFCP PHASE2:Mm9::chr5:123439274..123439290,+#_4b64687bfcdefea0bfcad8e1805df6e6p4@ENSMUST00000148466, p4@uc008zmw.1
1.74e-65FFCP PHASE1:Mm9::chr5:123439274..123439290,+#_4b64687bfcdefea0bfcad8e1805df6e6p4@ENSMUST00000148466, p4@uc008zmw.1
2.25e-65FFCP PHASE2:Mm9::chr5:123465978..123465989,-#_f42a347de0b51dce535cc25bcb3dc074p@chr5:123465978..123465989, -
2.25e-65FFCP PHASE2:Mm9::chr1:140069290..140069308,+#_f42a347de0b51dce535cc25bcb3dc074p@chr1:140069290..140069308, +
2.25e-65FFCP PHASE1:Mm9::chr1:140069290..140069308,+#_f42a347de0b51dce535cc25bcb3dc074+, p@chr1:140069290..140069308
2.25e-65FFCP PHASE1:Mm9::chr5:123465978..123465989,-#_f42a347de0b51dce535cc25bcb3dc074p@chr5:123465978..123465989, -
2.25e-65FFCP PHASE1:Mm9::chr15:80403104..80403111,+#_f42a347de0b51dce535cc25bcb3dc074p10@Grap2
2.25e-65FFCP PHASE2:Mm9::chr15:80403104..80403111,+#_f42a347de0b51dce535cc25bcb3dc074p10@Grap2
2.9e-65FFCP PHASE2:Mm9::chr11:46200242..46200255,+#_7e92ac78f4ba05d003e9a4c8d0ad0c5cp@chr11:46200242..46200255, +
2.9e-65FFCP PHASE1:Mm9::chr11:46200242..46200255,+#_7e92ac78f4ba05d003e9a4c8d0ad0c5cp@chr11:46200242..46200255, +
2.9e-65FFCP PHASE2:Mm9::chr6:41504409..41504422,-#_7e92ac78f4ba05d003e9a4c8d0ad0c5cp@chr6:41504409..41504422, -
2.9e-65FFCP PHASE1:Mm9::chr14:54817583..54817593,-#_7e92ac78f4ba05d003e9a4c8d0ad0c5cp@chr14:54817583..54817593, -
2.9e-65FFCP PHASE2:Mm9::chr14:54817583..54817593,-#_7e92ac78f4ba05d003e9a4c8d0ad0c5cp@chr14:54817583..54817593, -
2.9e-65FFCP PHASE1:Mm9::chr6:41504409..41504422,-#_7e92ac78f4ba05d003e9a4c8d0ad0c5cp@chr6:41504409..41504422, -
3.74e-65FFCP PHASE1:Mm9::chr4:32328217..32328228,-#_21838e18a3445167eae1b5f9f9d9100ep@chr4:32328217..32328228, -
3.74e-65FFCP PHASE2:Mm9::chr4:32328217..32328228,-#_21838e18a3445167eae1b5f9f9d9100ep@chr4:32328217..32328228, -
6.21e-65FFCP PHASE1:Mm9::chr13:105412781..105412798,+#_a4967cb80b91d5b1645524c822a4009fp@chr13:105412781..105412798, +
6.21e-65FFCP PHASE2:Mm9::chr11:46200110..46200124,-#_a4967cb80b91d5b1645524c822a4009fp@chr11:46200110..46200124, -
6.21e-65FFCP PHASE1:Mm9::chr5:123465955..123465966,-#_a4967cb80b91d5b1645524c822a4009fp@chr5:123465955..123465966, -
6.21e-65FFCP PHASE2:Mm9::chr5:123465955..123465966,-#_a4967cb80b91d5b1645524c822a4009fp@chr5:123465955..123465966, -
6.21e-65FFCP PHASE2:Mm9::chr13:105412781..105412798,+#_a4967cb80b91d5b1645524c822a4009fp@chr13:105412781..105412798, +
6.21e-65FFCP PHASE1:Mm9::chr11:46200110..46200124,-#_a4967cb80b91d5b1645524c822a4009fp@chr11:46200110..46200124, -
1.0e-60FFCP PHASE1:Mm9::chr2:11097490..11097500,+#_be9860812276d09800454363d898d692p@chr2:11097490..11097500, +
1.0e-60FFCP PHASE2:Mm9::chr2:11097490..11097500,+#_be9860812276d09800454363d898d692p@chr2:11097490..11097500, +
1.33e-60FFCP PHASE2:Mm9::chr7:150943007..150943022,+#_4fdb861e76e71aeb0ba3dc386fa81960p@chr7:150943007..150943022, +
1.33e-60FFCP PHASE2:Mm9::chr10:128157769..128157772,-#_4fdb861e76e71aeb0ba3dc386fa81960p@chr10:128157769..128157772, -
1.33e-60FFCP PHASE2:Mm9::chr12:70398221..70398232,-#_4fdb861e76e71aeb0ba3dc386fa81960p@chr12:70398221..70398232, -
1.33e-60FFCP PHASE1:Mm9::chr7:150943007..150943022,+#_4fdb861e76e71aeb0ba3dc386fa81960p@chr7:150943007..150943022, +
1.33e-60FFCP PHASE1:Mm9::chr5:108160486..108160515,-#_4fdb861e76e71aeb0ba3dc386fa81960p@chr5:108160486..108160515, -
1.33e-60FFCP PHASE1:Mm9::chr10:128157769..128157772,-#_4fdb861e76e71aeb0ba3dc386fa81960p@chr10:128157769..128157772, -
1.33e-60FFCP PHASE2:Mm9::chr5:108160486..108160515,-#_4fdb861e76e71aeb0ba3dc386fa81960p@chr5:108160486..108160515, -
1.33e-60FFCP PHASE1:Mm9::chr12:70398221..70398232,-#_4fdb861e76e71aeb0ba3dc386fa81960p@chr12:70398221..70398232, -
1.77e-60FFCP PHASE2:Mm9::chr14:53414758..53414769,+#_67bf24132681babbe7e4729cb19b0443p1@ENSMUST00000103582
1.77e-60FFCP PHASE1:Mm9::chr14:53414758..53414769,+#_67bf24132681babbe7e4729cb19b0443p1@ENSMUST00000103582
2.34e-60FFCP PHASE2:Mm9::chr2:73290853..73290866,+#_afea924e28698ad2287a1c8d23f565e0p@chr2:73290853..73290866, +
2.34e-60FFCP PHASE1:Mm9::chr2:73290853..73290866,+#_afea924e28698ad2287a1c8d23f565e0p@chr2:73290853..73290866, +
4.1e-60FFCP PHASE2:Mm9::chr1:138476217..138476228,+#_0240567d7c98d907e6a828635dea701ap@chr1:138476217..138476228, +
4.1e-60FFCP PHASE2:Mm9::chr9:14708434..14708444,-#_0240567d7c98d907e6a828635dea701ap8@Folr4
4.1e-60FFCP PHASE2:Mm9::chr2:11181142..11181148,-#_0240567d7c98d907e6a828635dea701ap@chr2:11181142..11181148, -
4.1e-60FFCP PHASE1:Mm9::chr2:11181142..11181148,-#_0240567d7c98d907e6a828635dea701ap@chr2:11181142..11181148, -
4.1e-60FFCP PHASE1:Mm9::chr1:138476217..138476228,+#_0240567d7c98d907e6a828635dea701ap@chr1:138476217..138476228, +
4.1e-60FFCP PHASE1:Mm9::chr9:14708434..14708444,-#_0240567d7c98d907e6a828635dea701ap8@Folr4
6.9e-59FFCP PHASE2:Mm9::chr11:87558695..87558707,+#_f7f3b923569be3724be3bf570e336e5fp@chr11:87558695..87558707, +
6.9e-59FFCP PHASE1:Mm9::chrX:54465221..54465232,+#_f7f3b923569be3724be3bf570e336e5fp4@Cd40lg
6.9e-59FFCP PHASE1:Mm9::chrX:54477240..54477286,+#_f7f3b923569be3724be3bf570e336e5fp@chrX:54477240..54477286, +
6.9e-59FFCP PHASE2:Mm9::chrX:54465221..54465232,+#_f7f3b923569be3724be3bf570e336e5fp4@Cd40lg
6.9e-59FFCP PHASE2:Mm9::chrX:54477240..54477286,+#_f7f3b923569be3724be3bf570e336e5fp@chrX:54477240..54477286, +
6.9e-59FFCP PHASE1:Mm9::chr11:87558695..87558707,+#_f7f3b923569be3724be3bf570e336e5fp@chr11:87558695..87558707, +
1.09e-58FFCP PHASE1:Mm9::chr4:32339235..32339263,+#_6fdd623e858564378f180d21e17241d5p@chr4:32339235..32339263, +
1.09e-58FFCP PHASE2:Mm9::chr4:32339235..32339263,+#_6fdd623e858564378f180d21e17241d5p@chr4:32339235..32339263, +
1.71e-58FFCP PHASE2:Mm9::chr16:23175296..23175310,+#_9d748b65baaf4d5a9b25e5f8531d7deep3@uc007ytl.1
1.71e-58FFCP PHASE1:Mm9::chr19:10904395..10904400,-#_9d748b65baaf4d5a9b25e5f8531d7deep5@Cd6
1.71e-58FFCP PHASE1:Mm9::chr16:23175296..23175310,+#_9d748b65baaf4d5a9b25e5f8531d7deep3@uc007ytl.1
1.71e-58FFCP PHASE2:Mm9::chr19:10904395..10904400,-#_9d748b65baaf4d5a9b25e5f8531d7deep5@Cd6
2.15e-58FFCP PHASE1:Mm9::chr14:54831123..54831141,+#_699bc42111bc677c6019206000b43320p1@ENSMUST00000103733
2.15e-58FFCP PHASE2:Mm9::chr14:54831123..54831141,+#_699bc42111bc677c6019206000b43320p1@ENSMUST00000103733
2.69e-58FFCP PHASE1:Mm9::chr4:151490126..151490137,+#_c3b11b2d74812c5f18eb21da7eac0029p3@Tnfrsf25
2.69e-58FFCP PHASE2:Mm9::chr4:32339511..32339518,+#_c3b11b2d74812c5f18eb21da7eac0029p@chr4:32339511..32339518, +
2.69e-58FFCP PHASE1:Mm9::chr4:32339511..32339518,+#_c3b11b2d74812c5f18eb21da7eac0029p@chr4:32339511..32339518, +
2.69e-58FFCP PHASE2:Mm9::chr4:151490126..151490137,+#_c3b11b2d74812c5f18eb21da7eac0029p3@Tnfrsf25
3.38e-58FFCP PHASE2:Mm9::chr6:48656532..48656548,+#_d5000e82374c3c518ff90268487e7bc7p@chr6:48656532..48656548, +
3.38e-58FFCP PHASE1:Mm9::chr6:48656532..48656548,+#_d5000e82374c3c518ff90268487e7bc7p@chr6:48656532..48656548, +
3.91e-58FFCP PHASE1:Mm9::chr4:119635138..119635148,-#_f485e583b22d18224a7950ea95c0ac67p@chr4:119635138..119635148, -
3.91e-58FFCP PHASE2:Mm9::chr19:5638280..5638306,+#_f485e583b22d18224a7950ea95c0ac67p@chr19:5638280..5638306, +