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Coexpression cluster:C90

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Full id: C90_neuroectodermal_peripheral_neuroepithelioma_neuroblastoma_carcinoid_parietal_putamen



Phase1 CAGE Peaks

  Short description
Hg19::chr10:118897577..118897600,- p5@VAX1
Hg19::chr10:118898078..118898093,- p3@VAX1
Hg19::chr10:118898132..118898140,- p9@VAX1
Hg19::chr10:132938202..132938217,- p@chr10:132938202..132938217
-
Hg19::chr10:50857941..50857943,+ +
p@chr10:50857941..50857943
Hg19::chr10:50864356..50864359,+ p@chr10:50864356..50864359
+
Hg19::chr10:50881798..50881801,+ p@chr10:50881798..50881801
+
Hg19::chr10:71695706..71695736,- p@chr10:71695706..71695736
-
Hg19::chr10:71696103..71696151,- p@chr10:71696103..71696151
-
Hg19::chr10:71812074..71812078,+ p5@H2AFY2
Hg19::chr10:71812102..71812136,+ p3@H2AFY2
Hg19::chr11:15989432..15989436,- p17@SOX6
Hg19::chr11:16000244..16000250,- p@chr11:16000244..16000250
-
Hg19::chr11:16015978..16015981,- p@chr11:16015978..16015981
-
Hg19::chr11:16117457..16117461,- p@chr11:16117457..16117461
-
Hg19::chr11:16125602..16125625,- p@chr11:16125602..16125625
-
Hg19::chr11:16377727..16377766,- p@chr11:16377727..16377766
-
Hg19::chr11:16377955..16378017,- p@chr11:16377955..16378017
-
Hg19::chr11:16378028..16378044,- p@chr11:16378028..16378044
-
Hg19::chr11:16378048..16378071,- p@chr11:16378048..16378071
-
Hg19::chr11:16378085..16378097,- p@chr11:16378085..16378097
-
Hg19::chr11:16629597..16629610,- p25@SOX6
Hg19::chr11:16629621..16629629,- p30@SOX6
Hg19::chr11:16629630..16629643,- p20@SOX6
Hg19::chr11:16629650..16629667,- p22@SOX6
Hg19::chr11:16630036..16630039,- p@chr11:16630036..16630039
-
Hg19::chr11:16630054..16630060,- p@chr11:16630054..16630060
-
Hg19::chr11:16630068..16630078,- p@chr11:16630068..16630078
-
Hg19::chr11:16630089..16630102,- p@chr11:16630089..16630102
-
Hg19::chr11:16630144..16630146,- p@chr11:16630144..16630146
-
Hg19::chr11:16633687..16633732,- p@chr11:16633687..16633732
-
Hg19::chr11:16633751..16633768,- p@chr11:16633751..16633768
-
Hg19::chr11:83317672..83317677,- p@chr11:83317672..83317677
-
Hg19::chr11:83436107..83436115,- p46@DLG2
Hg19::chr12:114791999..114792001,- p@chr12:114791999..114792001
-
Hg19::chr12:114798682..114798690,- p@chr12:114798682..114798690
-
Hg19::chr12:114798704..114798714,- p@chr12:114798704..114798714
-
Hg19::chr12:114798729..114798733,- p@chr12:114798729..114798733
-
Hg19::chr12:114798826..114798847,- p@chr12:114798826..114798847
-
Hg19::chr12:114829979..114829984,- p@chr12:114829979..114829984
-
Hg19::chr12:114837394..114837405,- p@chr12:114837394..114837405
-
Hg19::chr12:114845810..114845824,- p1@TBX5
Hg19::chr12:114845834..114845848,- p5@TBX5
Hg19::chr12:114845861..114845868,- p12@TBX5
Hg19::chr12:114845970..114846000,+ p1@LOC255480
Hg19::chr12:18242272..18242295,- p4@RERGL
Hg19::chr12:18243080..18243091,- p3@RERGL
Hg19::chr12:18243103..18243118,- p2@RERGL
Hg19::chr12:18243119..18243133,- p1@RERGL
Hg19::chr12:80707347..80707351,+ p@chr12:80707347..80707351
+
Hg19::chr13:100951268..100951280,+ p@chr13:100951268..100951280
+
Hg19::chr13:38558628..38558643,- p@chr13:38558628..38558643
-
Hg19::chr13:39648479..39648502,+ +
p@chr13:39648479..39648502
Hg19::chr13:39650556..39650592,+ p@chr13:39650556..39650592
+
Hg19::chr14:97674516..97674526,- p@chr14:97674516..97674526
-
Hg19::chr14:97682312..97682318,+ +
p@chr14:97682312..97682318
Hg19::chr15:78110780..78110799,+ p@chr15:78110780..78110799
+
Hg19::chr15:78111373..78111388,- p@chr15:78111373..78111388
-
Hg19::chr16:25736373..25736377,+ p@chr16:25736373..25736377
+
Hg19::chr16:25741429..25741437,+ p@chr16:25741429..25741437
+
Hg19::chr16:25741486..25741495,+ +
p@chr16:25741486..25741495
Hg19::chr16:25766149..25766153,+ p@chr16:25766149..25766153
+
Hg19::chr16:25807276..25807277,+ p@chr16:25807276..25807277
+
Hg19::chr16:25842052..25842056,+ p@chr16:25842052..25842056
+
Hg19::chr16:25858350..25858351,+ p@chr16:25858350..25858351
+
Hg19::chr16:25883932..25883941,+ p@chr16:25883932..25883941
+
Hg19::chr16:25884405..25884421,+ p@chr16:25884405..25884421
+
Hg19::chr16:25884530..25884541,+ p@chr16:25884530..25884541
+
Hg19::chr16:25885675..25885684,+ p@chr16:25885675..25885684
+
Hg19::chr16:25894488..25894490,+ p@chr16:25894488..25894490
+
Hg19::chr16:61905717..61905720,- p@chr16:61905717..61905720
-
Hg19::chr16:62070488..62070510,+ p@chr16:62070488..62070510
+
Hg19::chr16:62070534..62070537,+ p@chr16:62070534..62070537
+
Hg19::chr16:78738655..78738675,+ p@chr16:78738655..78738675
+
Hg19::chr17:31618260..31618271,+ p@chr17:31618260..31618271
+
Hg19::chr17:31624987..31624990,+ p@chr17:31624987..31624990
+
Hg19::chr17:39890893..39890898,- p1@HAP1
Hg19::chr17:43972989..43973035,- p1@LOC100128977
Hg19::chr17:43973042..43973067,- p2@LOC100128977
Hg19::chr17:46799872..46799887,- p1@PRAC
Hg19::chr17:46800319..46800343,- p2@PRAC
Hg19::chr17:46882304..46882321,- p@chr17:46882304..46882321
-
Hg19::chr17:46882324..46882346,- p@chr17:46882324..46882346
-
Hg19::chr17:6946298..6946321,- p@chr17:6946298..6946321
-
Hg19::chr17:7078552..7078564,+ p@chr17:7078552..7078564
+
Hg19::chr17:7080763..7080778,- p10@ASGR1
Hg19::chr17:7080802..7080850,- p2@ASGR1
Hg19::chr17:7080851..7080863,- p7@ASGR1
Hg19::chr17:7115019..7115065,- p@chr17:7115019..7115065
-
Hg19::chr18:50329052..50329058,+ p@chr18:50329052..50329058
+
Hg19::chr19:15580880..15580942,- p@chr19:15580880..15580942
-
Hg19::chr19:15580961..15580969,- p@chr19:15580961..15580969
-
Hg19::chr19:15619299..15619308,+ p2@CYP4F22
Hg19::chr19:49713991..49714040,+ p@chr19:49713991..49714040
+
Hg19::chr19:49714044..49714055,+ +
p@chr19:49714044..49714055
Hg19::chr19:49725100..49725103,+ p@chr19:49725100..49725103
+
Hg19::chr19:50000746..50000765,+ p1@SNORD35B
Hg19::chr19:50016671..50016675,+ p22@FCGRT
Hg19::chr19:50024944..50024947,+ p@chr19:50024944..50024947
+
Hg19::chr1:185717192..185717195,+ p@chr1:185717192..185717195
+
Hg19::chr1:185720104..185720113,+ p@chr1:185720104..185720113
+
Hg19::chr1:185846482..185846486,+ p@chr1:185846482..185846486
+
Hg19::chr1:185853036..185853046,+ p@chr1:185853036..185853046
+
Hg19::chr1:185866241..185866248,+ p@chr1:185866241..185866248
+
Hg19::chr1:185958925..185958928,+ +
p@chr1:185958925..185958928
Hg19::chr1:186095617..186095620,+ p@chr1:186095617..186095620
+
Hg19::chr1:186116540..186116557,+ p@chr1:186116540..186116557
+
Hg19::chr1:186156032..186156038,+ p@chr1:186156032..186156038
+
Hg19::chr1:186159241..186159250,+ p@chr1:186159241..186159250
+
Hg19::chr1:18957333..18957375,+ p1@PAX7
Hg19::chr1:18957380..18957386,+ p10@PAX7
Hg19::chr1:209757051..209757069,+ p1@CAMK1G
Hg19::chr1:214161038..214161063,- p@chr1:214161038..214161063
-
Hg19::chr1:21766691..21766715,+ p3@NBPF3
Hg19::chr1:230041565..230041573,- -
p@chr1:230041565..230041573
Hg19::chr1:230041588..230041591,- p@chr1:230041588..230041591
-
Hg19::chr1:236851687..236851691,+ p@chr1:236851687..236851691
+
Hg19::chr1:236866756..236866760,+ p@chr1:236866756..236866760
+
Hg19::chr1:236883677..236883685,+ p@chr1:236883677..236883685
+
Hg19::chr1:236883935..236883939,+ +
p@chr1:236883935..236883939
Hg19::chr1:236888019..236888038,+ p@chr1:236888019..236888038
+
Hg19::chr1:236888159..236888162,+ p@chr1:236888159..236888162
+
Hg19::chr1:236893586..236893590,+ p@chr1:236893586..236893590
+
Hg19::chr1:236895237..236895246,+ p@chr1:236895237..236895246
+
Hg19::chr1:236904639..236904648,+ +
p@chr1:236904639..236904648
Hg19::chr1:236931738..236931742,+ p@chr1:236931738..236931742
+
Hg19::chr1:247297360..247297367,+ p@chr1:247297360..247297367
+
Hg19::chr1:38502134..38502142,- p@chr1:38502134..38502142
-
Hg19::chr1:60313952..60313962,+ p@chr1:60313952..60313962
+
Hg19::chr1:60313967..60313974,+ p@chr1:60313967..60313974
+
Hg19::chr1:86827881..86827900,- p@chr1:86827881..86827900
-
Hg19::chr1:86938045..86938051,- p@chr1:86938045..86938051
-
Hg19::chr1:86938076..86938081,- p@chr1:86938076..86938081
-
Hg19::chr1:86938084..86938088,- p@chr1:86938084..86938088
-
Hg19::chr1:86964268..86964277,+ p@chr1:86964268..86964277
+
Hg19::chr1:86964280..86964295,+ +
p@chr1:86964280..86964295
Hg19::chr1:86964312..86964323,+ p@chr1:86964312..86964323
+
Hg19::chr20:4228155..4228166,+ p@chr20:4228155..4228166
+
Hg19::chr20:4228171..4228192,+ p@chr20:4228171..4228192
+
Hg19::chr20:4228201..4228214,+ p@chr20:4228201..4228214
+
Hg19::chr20:4228233..4228238,+ p@chr20:4228233..4228238
+
Hg19::chr20:4228244..4228251,+ p@chr20:4228244..4228251
+
Hg19::chr21:41955829..41955834,- p@chr21:41955829..41955834
-
Hg19::chr21:42198965..42198972,- p@chr21:42198965..42198972
-
Hg19::chr22:39207648..39207661,- p@chr22:39207648..39207661
-
Hg19::chr2:166979731..166979732,- -
p@chr2:166979731..166979732
Hg19::chr2:183712795..183712798,- p@chr2:183712795..183712798
-
Hg19::chr2:183868223..183868260,- p@chr2:183868223..183868260
-
Hg19::chr2:218876099..218876142,- p@chr2:218876099..218876142
-
Hg19::chr2:228754609..228754626,+ p@chr2:228754609..228754626
+
Hg19::chr2:242937020..242937026,+ p@chr2:242937020..242937026
+
Hg19::chr3:131718082..131718086,- p@chr3:131718082..131718086
-
Hg19::chr3:131753790..131753801,- p3@CPNE4
Hg19::chr4:1562242..1562255,+ p@chr4:1562242..1562255
+
Hg19::chr4:1562269..1562275,+ p@chr4:1562269..1562275
+
Hg19::chr4:1562312..1562319,+ p@chr4:1562312..1562319
+
Hg19::chr4:1574584..1574600,+ p@chr4:1574584..1574600
+
Hg19::chr4:1574650..1574668,+ p@chr4:1574650..1574668
+
Hg19::chr4:187322326..187322329,- p@chr4:187322326..187322329
-
Hg19::chr4:82634425..82634427,- p@chr4:82634425..82634427
-
Hg19::chr5:111035724..111035730,- p@chr5:111035724..111035730
-
Hg19::chr5:132531396..132531398,- p@chr5:132531396..132531398
-
Hg19::chr6:13814036..13814054,+ p@chr6:13814036..13814054
+
Hg19::chr6:29944918..29944949,- p@chr6:29944918..29944949
-
Hg19::chr6:33175140..33175167,+ p2@MIR219-1
Hg19::chr6:6002642..6002653,- p@chr6:6002642..6002653
-
Hg19::chr6:6007064..6007075,- p5@NRN1
Hg19::chr7:121944689..121944705,- p2@FEZF1
Hg19::chr7:121944796..121944814,- p1@FEZF1
Hg19::chr7:121944948..121944985,+ p1@ENST00000437317
Hg19::chr7:121945005..121945046,+ p2@ENST00000437317
Hg19::chr7:121945047..121945052,+ p6@ENST00000437317
Hg19::chr7:121945161..121945169,+ p4@ENST00000437317
Hg19::chr7:121945203..121945213,+ p3@ENST00000437317
Hg19::chr7:123674206..123674214,- p@chr7:123674206..123674214
-
Hg19::chr7:129991457..129991472,- p@chr7:129991457..129991472
-
Hg19::chr7:19148521..19148527,- p@chr7:19148521..19148527
-
Hg19::chr8:107072791..107072808,- p2@ENST00000520433
Hg19::chr8:12808701..12808712,+ p16@KIAA1456
Hg19::chr8:12808834..12808898,+ p4@KIAA1456
Hg19::chr8:12809275..12809298,+ p2@KIAA1456
Hg19::chr8:12809300..12809317,+ p5@KIAA1456
Hg19::chr8:12810112..12810134,+ p@chr8:12810112..12810134
+
Hg19::chr8:12810136..12810161,+ p@chr8:12810136..12810161
+
Hg19::chr8:12866747..12866757,+ +
p@chr8:12866747..12866757
Hg19::chr8:12878732..12878750,+ p@chr8:12878732..12878750
+
Hg19::chr8:27080859..27080874,+ p@chr8:27080859..27080874
+
Hg19::chr8:27108843..27108849,+ p@chr8:27108843..27108849
+
Hg19::chr8:27118247..27118250,+ p@chr8:27118247..27118250
+
Hg19::chr8:50822747..50822761,- p@chr8:50822747..50822761
-
Hg19::chr9:138048874..138048890,- p@chr9:138048874..138048890
-
Hg19::chr9:138048894..138048904,- p@chr9:138048894..138048904
-
Hg19::chr9:14780426..14780431,- p@chr9:14780426..14780431
-
Hg19::chr9:14910922..14910928,- p24@FREM1
Hg19::chr9:14910957..14910964,- p23@FREM1
Hg19::chr9:14910990..14910995,- p25@FREM1
Hg19::chr9:14993142..14993181,- p@chr9:14993142..14993181
-
Hg19::chr9:16007885..16007892,+ p@chr9:16007885..16007892
+
Hg19::chr9:80264105..80264126,- p@chr9:80264105..80264126
-
Hg19::chrX:117119262..117119297,- p4@KLHL13
Hg19::chrX:19140237..19140247,- p@chrX:19140237..19140247
-
Hg19::chrX:19140694..19140760,- p2@GPR64
Hg19::chrX:19141065..19141080,- p3@GPR64
Hg19::chrX:52685427..52685450,+ p12@OAT
Hg19::chrX:52686443..52686456,+ p@chrX:52686443..52686456
+


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0007275multicellular organismal development0.0325330912060701
GO:0004587ornithine-oxo-acid transaminase activity0.0325330912060701
GO:0060044negative regulation of cardiac muscle cell proliferation0.0325330912060701
GO:0060039pericardium development0.0325330912060701
GO:0032501multicellular organismal process0.0325330912060701
GO:0051890regulation of cardioblast differentiation0.0325330912060701
GO:0051891positive regulation of cardioblast differentiation0.0325330912060701
GO:0007549dosage compensation0.0325330912060701
GO:0060043regulation of cardiac muscle cell proliferation0.0325330912060701
GO:0032502developmental process0.0325330912060701
GO:0035117embryonic arm morphogenesis0.0325330912060701
GO:0035140arm morphogenesis0.0325330912060701
GO:0001740Barr body0.0325330912060701
GO:0004873asialoglycoprotein receptor activity0.0325330912060701
GO:0000805X chromosome0.0325330912060701
GO:0010002cardioblast differentiation0.038709355173715
GO:0035136forelimb morphogenesis0.038709355173715
GO:0005954calcium- and calmodulin-dependent protein kinase complex0.038709355173715
GO:0035115embryonic forelimb morphogenesis0.038709355173715
GO:0000803sex chromosome0.038709355173715
GO:0001739sex chromatin0.038709355173715
GO:0060038cardiac muscle cell proliferation0.0424007559487827
GO:0014855striated muscle cell proliferation0.0424007559487827
GO:0006591ornithine metabolic process0.0499846624744467
GO:0035051cardiac cell differentiation0.0499846624744467
GO:0019864IgG binding0.0499846624744467



Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


uberon_data
disease_data


Uber Anatomy
Ontology termp-valuen
sympathetic nervous system7.49e-085
autonomic nervous system7.49e-085
Disease
Ontology termp-valuen
neuroectodermal tumor4.26e-8210
germ cell and embryonal cancer9.20e-3822
germ cell cancer9.20e-3822
neuroendocrine tumor9.49e-076


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.11.17166e-14
MA0004.10.0161544
MA0006.10.0267162
MA0007.10.0486405
MA0009.10.378772
MA0014.11.50616e-08
MA0017.10.0390911
MA0019.10.495421
MA0024.10.00609035
MA0025.10.0423182
MA0027.11.13906
MA0028.11.86805e-05
MA0029.10.236236
MA0030.10.219799
MA0031.10.26153
MA0038.10.664655
MA0040.11.66264
MA0041.10.591439
MA0042.10.577677
MA0043.10.194778
MA0046.10.358721
MA0048.10.00171999
MA0050.10.0538728
MA0051.10.0354866
MA0052.12.10816
MA0055.18.91567e-08
MA0056.10
MA0057.10.738729
MA0058.10.00997738
MA0059.10.0041527
MA0060.10.0145586
MA0061.11.47181e-05
MA0063.10
MA0066.10.141244
MA0067.10.345089
MA0068.11.84223
MA0069.10.35175
MA0070.11.17963
MA0071.10.239853
MA0072.10.324075
MA0073.10.13467
MA0074.10.133161
MA0076.15.86983e-06
MA0077.10.0574218
MA0078.10.330945
MA0081.10.303333
MA0083.12.72279
MA0084.10.588993
MA0087.11.95304
MA0088.10.0136519
MA0089.10
MA0090.10.242079
MA0091.10.380468
MA0092.10.249621
MA0093.10.00379816
MA0095.10
MA0098.10
MA0100.10.00597625
MA0101.10.00177576
MA0103.10.0112397
MA0105.10.000180959
MA0106.10.211957
MA0107.17.274e-05
MA0108.20.136132
MA0109.10
MA0111.10.135672
MA0113.10.145795
MA0114.10.0648849
MA0115.10.0755631
MA0116.10.0214829
MA0117.10.0963027
MA0119.10.0462583
MA0122.10.505935
MA0124.10.221046
MA0125.10.972839
MA0130.10
MA0131.10.0246953
MA0132.10
MA0133.10
MA0135.11.04756
MA0136.10.151566
MA0139.10.000108942
MA0140.10.00746575
MA0141.10.00395555
MA0142.10.763488
MA0143.10.245581
MA0144.10.00265116
MA0145.10.000165207
MA0146.11.4303e-09
MA0147.10.00182082
MA0148.10.624557
MA0149.197.6018
MA0062.22.28764e-07
MA0035.20.0854449
MA0039.23.12604e-06
MA0138.20.0536952
MA0002.20.18459
MA0137.20.0030437
MA0104.20.00054827
MA0047.21.90122
MA0112.20.00195729
MA0065.20.0496781
MA0150.10.0613134
MA0151.10
MA0152.11.6033
MA0153.10.583461
MA0154.10.00927313
MA0155.10.0237235
MA0156.10.00042812
MA0157.10.895526
MA0158.10
MA0159.10.301227
MA0160.10.032557
MA0161.10
MA0162.15.10106e-08
MA0163.11.72493e-06
MA0164.10.58986
MA0080.20.00819734
MA0018.20.0280599
MA0099.20.00847154
MA0079.20.00922246
MA0102.20.22667
MA0258.10.240831
MA0259.10.151142
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
SUZ12#23512184.400410031215282.08786291113617e-071.11765409828883e-05



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data