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DOID:3571

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Name:liver cancer
Namespace:FANTOM
Definition:"A gastrointestinal system cancer that is located_in the liver." [url:http://en.wikipedia.org/wiki/Liver]
Xrefs:
links:

MSH:D008113
SNOMEDCT_2010_1_31:126851005
SNOMEDCT_2010_1_31:154470007
SNOMEDCT_2010_1_31:187768001
SNOMEDCT_2010_1_31:187771009
SNOMEDCT_2010_1_31:187779006
SNOMEDCT_2010_1_31:269548006
SNOMEDCT_2010_1_31:363361004
SNOMEDCT_2010_1_31:93870000
SNOMEDCT_2010_1_31:95214007
UMLS_CUI:C0023903
UMLS_CUI:C0024620
UMLS_CUI:C0345904
UMLS_CUI:C0854795
UMLS_CUI:C0861869

UMLS_CUI:C1334590
Synonyms: "ca liver - primary" EXACT []
"Ca liver - primary (disorder)" EXACT [SNOMEDCT_2005_07_31:269548006]
"hepatic cancer" EXACT [CSP2005:2003-2810]
"hepatic neoplasm" EXACT [CSP2005:2003-2810]
"malignant hepato-biliary neoplasm" EXACT []
"malignant neoplasm of liver" EXACT []
"malignant neoplasm of liver (disorder)" EXACT [SNOMEDCT_2005_07_31:93870000]
"malignant neoplasm of liver unspecified (disorder)" EXACT [SNOMEDCT_2005_07_31:187779006]
"malignant neoplasm of liver, not specified as primary or secondary" EXACT [ICD9CM_2006:155.2]
"malignant neoplasm of liver, primary" EXACT [ICD9CM_2006:155.0]
"malignant tumor of liver (disorder)" EXACT [SNOMEDCT_2005_07_31:363361004]
"neoplasm of liver (disorder)" EXACT [SNOMEDCT_2005_07_31:126851005]
"non-resectable primary hepatic malignant neoplasm" EXACT []
"primary liver cancer" EXACT []
"primary malignant neoplasm of Liver" EXACT [NCI2004_11_17:C34803]
"primary malignant neoplasm of liver" EXACT [SNOMEDCT_2005_07_31:187768001, SNOMEDCT_2005_07_31:93870000]
"primary malignant neoplasm of liver (disorder)" EXACT [SNOMEDCT_2005_07_31:95214007]
"primary malignant neoplasm of liver NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:187771009]
"Resectable malignant neoplasm of Liver" EXACT [NCI2004_11_17:C7692]
"resectable malignant neoplasm of the liver" EXACT []
Alt_id: DOID:12300
DOID:269
DOID:7330
DOID:915
DOID:919

Ontology association
Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.

link to ontology dataset
data

Parents

is_a:DOID:3119(gastrointestinal system cancer)



Children


is a:FF:10778-110G4 (hepatic mesenchymal tumor cell line:LI90),DOID:686 (liver carcinoma),DOID:687 (hepatoblastoma)


Ontology Tree: Loaded from BioPortal

FF samples

Human (Homo sapiens)

Mouse (Mus musculus)

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:3571 (liver cancer), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data

P-valueFFCPShort description
2.55e-98FFCP PHASE1:Hg19::chr13:38275506..38275512,-#_f9cf370e5b66b6df35a92cf7b226209fp@chr13:38275506..38275512, -
2.55e-98FFCP PHASE2:Hg19::chr13:38275506..38275512,-#_f9cf370e5b66b6df35a92cf7b226209fp@chr13:38275506..38275512, -
6.58e-50FFCP PHASE1:Hg19::chr19:10402114..10402120,+#_f5cb02c3ba8c4626f2963bb22eb9e84bp6@ICAM5
6.58e-50FFCP PHASE2:Hg19::chr19:10402114..10402120,+#_f5cb02c3ba8c4626f2963bb22eb9e84bp6@ICAM5
6.58e-50FFCP PHASE2:Hg19::chr21:47424477..47424486,+#_f5cb02c3ba8c4626f2963bb22eb9e84bp@chr21:47424477..47424486, +
6.58e-50FFCP PHASE1:Hg19::chr21:47424477..47424486,+#_f5cb02c3ba8c4626f2963bb22eb9e84bp@chr21:47424477..47424486, +
6.62e-41FFCP PHASE1:Hg19::chr2:217538399..217538408,-#_c01de8a807c4ffbc3e2641576222d893p75@IGFBP5
6.62e-41FFCP PHASE2:Hg19::chr2:217538399..217538408,-#_c01de8a807c4ffbc3e2641576222d893p75@IGFBP5
1.48e-40FFCP PHASE1:Hg19::chr12:109094948..109094959,-#_21d9a7dcb034f7492532e32076809206p31@CORO1C
1.48e-40FFCP PHASE1:Hg19::chr6:169588737..169588744,-#_21d9a7dcb034f7492532e32076809206p@chr6:169588737..169588744, -
1.48e-40FFCP PHASE2:Hg19::chr12:109094948..109094959,-#_21d9a7dcb034f7492532e32076809206p31@CORO1C
1.48e-40FFCP PHASE2:Hg19::chr6:169588737..169588744,-#_21d9a7dcb034f7492532e32076809206p@chr6:169588737..169588744, -
2.21e-40FFCP PHASE2:Hg19::chr2:133426030..133426041,-#_a078ebefb0726ab60932fa0f414ec53ep@chr2:133426030..133426041, -
2.21e-40FFCP PHASE2:Hg19::chr14:80090211..80090214,+#_a078ebefb0726ab60932fa0f414ec53ep@chr14:80090211..80090214, +
2.21e-40FFCP PHASE1:Hg19::chr2:133426030..133426041,-#_a078ebefb0726ab60932fa0f414ec53ep@chr2:133426030..133426041, -
2.21e-40FFCP PHASE1:Hg19::chr14:80090211..80090214,+#_a078ebefb0726ab60932fa0f414ec53ep@chr14:80090211..80090214, +
3.61e-34FFCP PHASE1:Hg19::chr5:167396347..167396349,+#_ba6072bc176bf364cabb22cec8c29d77p@chr5:167396347..167396349, +
3.61e-34FFCP PHASE2:Hg19::chr5:167396347..167396349,+#_ba6072bc176bf364cabb22cec8c29d77p@chr5:167396347..167396349, +
7.48e-30FFCP PHASE2:Hg19::chr7:41729165..41729178,-#_20c620d88660dbcb5a71c8b4d6c3b94ap@chr7:41729165..41729178, -
7.48e-30FFCP PHASE1:Hg19::chr7:41729165..41729178,-#_20c620d88660dbcb5a71c8b4d6c3b94ap@chr7:41729165..41729178, -
1.78e-29FFCP PHASE2:Hg19::chrX:149716271..149716273,+#_8fd6b2e34da8e9b7c5a2a373c3bc0530p@chrX:149716271..149716273, +
1.78e-29FFCP PHASE2:Hg19::chr2:217536930..217536944,-#_8fd6b2e34da8e9b7c5a2a373c3bc0530p@chr2:217536930..217536944, -
1.78e-29FFCP PHASE1:Hg19::chrX:149716271..149716273,+#_8fd6b2e34da8e9b7c5a2a373c3bc0530p@chrX:149716271..149716273, +
1.78e-29FFCP PHASE1:Hg19::chr2:217536930..217536944,-#_8fd6b2e34da8e9b7c5a2a373c3bc0530p@chr2:217536930..217536944, -
2.37e-29FFCP PHASE2:Hg19::chr16:71123774..71123782,+#_753c59b6635236623b52b06aba6fabef+, p@chr16:71123774..71123782
2.37e-29FFCP PHASE1:Hg19::chr16:71123774..71123782,+#_753c59b6635236623b52b06aba6fabefp@chr16:71123774..71123782, +
3.16e-29FFCP PHASE2:Hg19::chr7:136553339..136553348,+#_90bc52b0789efc2d3b6d93d6efbd1584p11@CHRM2
3.16e-29FFCP PHASE1:Hg19::chr7:136553339..136553348,+#_90bc52b0789efc2d3b6d93d6efbd1584p11@CHRM2
3.16e-29FFCP PHASE1:Hg19::chr9:21505583..21505593,-#_90bc52b0789efc2d3b6d93d6efbd1584p@chr9:21505583..21505593, -
3.16e-29FFCP PHASE2:Hg19::chr9:21505583..21505593,-#_90bc52b0789efc2d3b6d93d6efbd1584-, p@chr9:21505583..21505593
4.61e-26FFCP PHASE2:Hg19::chr3:141103437..141103451,+#_3792ab777780d2e9e137e1d5a97fc7b5p55@ZBTB38
4.61e-26FFCP PHASE1:Hg19::chr15:33018927..33018930,+#_3792ab777780d2e9e137e1d5a97fc7b5p@chr15:33018927..33018930, +
4.61e-26FFCP PHASE2:Hg19::chr15:33018927..33018930,+#_3792ab777780d2e9e137e1d5a97fc7b5p@chr15:33018927..33018930, +
4.61e-26FFCP PHASE1:Hg19::chr3:141103437..141103451,+#_3792ab777780d2e9e137e1d5a97fc7b5p55@ZBTB38
5.93e-26FFCP PHASE2:Hg19::chr1:172972632..172972638,+#_2e8f1c570467ac49add6287ab4e8e3cdp@chr1:172972632..172972638, +
5.93e-26FFCP PHASE1:Hg19::chr1:172972632..172972638,+#_2e8f1c570467ac49add6287ab4e8e3cdp@chr1:172972632..172972638, +
7.62e-26FFCP PHASE1:Hg19::chr4:95508126..95508142,+#_0182757e036dd40fd731f7476662dc7cp@chr4:95508126..95508142, +
7.62e-26FFCP PHASE2:Hg19::chr4:95508126..95508142,+#_0182757e036dd40fd731f7476662dc7cp@chr4:95508126..95508142, +
9.79e-26FFCP PHASE1:Hg19::chr21:38071760..38071776,+#_7a080033518eb44593b6b3160a93d722p5@SIM2
9.79e-26FFCP PHASE2:Hg19::chr12:12272276..12272282,-#_7a080033518eb44593b6b3160a93d722p@chr12:12272276..12272282, -
9.79e-26FFCP PHASE1:Hg19::chr12:12272276..12272282,-#_7a080033518eb44593b6b3160a93d722p@chr12:12272276..12272282, -
9.79e-26FFCP PHASE2:Hg19::chr21:38071760..38071776,+#_7a080033518eb44593b6b3160a93d722p5@SIM2
1.26e-25FFCP PHASE2:Hg19::chr15:39486488..39486494,-#_45c36a51c37d8b778d6c2bfd66d34bacp6@ENST00000560743
1.26e-25FFCP PHASE1:Hg19::chr15:39486488..39486494,-#_45c36a51c37d8b778d6c2bfd66d34bacp6@ENST00000560743
2.1e-23FFCP PHASE1:Hg19::chr9:119164000..119164021,+#_063a9fb19019c2b5672ccc0b7cd9ca8ap@chr9:119164000..119164021, +
2.1e-23FFCP PHASE2:Hg19::chr9:119164000..119164021,+#_063a9fb19019c2b5672ccc0b7cd9ca8ap@chr9:119164000..119164021, +
5.13e-23FFCP PHASE2:Hg19::chr6:52272474..52272475,-#_ce5ecf06379aba35d606fbb0047c4360p@chr6:52272474..52272475, -
5.13e-23FFCP PHASE1:Hg19::chr13:76258701..76258705,+#_ce5ecf06379aba35d606fbb0047c4360p@chr13:76258701..76258705, +
5.13e-23FFCP PHASE1:Hg19::chr6:52272474..52272475,-#_ce5ecf06379aba35d606fbb0047c4360p@chr6:52272474..52272475, -
5.13e-23FFCP PHASE2:Hg19::chr13:76258701..76258705,+#_ce5ecf06379aba35d606fbb0047c4360p@chr13:76258701..76258705, +
5.13e-23FFCP PHASE2:Hg19::chr2:27858182..27858185,+#_ce5ecf06379aba35d606fbb0047c4360p@chr2:27858182..27858185, +
5.13e-23FFCP PHASE1:Hg19::chr2:27858182..27858185,+#_ce5ecf06379aba35d606fbb0047c4360p@chr2:27858182..27858185, +
6.4e-23FFCP PHASE2:Hg19::chr5:14156841..14156863,+#_47390fd13fb35497b43c44b67f3faca9p@chr5:14156841..14156863, +
6.4e-23FFCP PHASE1:Hg19::chr5:14156841..14156863,+#_47390fd13fb35497b43c44b67f3faca9p@chr5:14156841..14156863, +
5.16e-21FFCP PHASE2:Hg19::chr6:132269901..132269911,-#_24d29aec9891b95c833f8615a4d2ee48p30@CTGF
5.16e-21FFCP PHASE1:Hg19::chr6:132269901..132269911,-#_24d29aec9891b95c833f8615a4d2ee48p30@CTGF
6.31e-21FFCP PHASE1:Hg19::chr10:97262828..97262865,-#_a79271896553fc41bf727d7cfcfac869p@chr10:97262828..97262865, -
6.31e-21FFCP PHASE2:Hg19::chr10:97262828..97262865,-#_a79271896553fc41bf727d7cfcfac869p@chr10:97262828..97262865, -
1.3e-19FFCP PHASE1:Hg19::chr14:55034385..55034400,+#_f83e245872cb40fb62b3878c1a4665cap20@SAMD4A
1.3e-19FFCP PHASE2:Hg19::chr14:55034385..55034400,+#_f83e245872cb40fb62b3878c1a4665cap20@SAMD4A
2.25e-19FFCP PHASE2:Hg19::chr2:134432699..134432711,-#_a38494a90217e9d624f638ca288d54b6p@chr2:134432699..134432711, -
2.25e-19FFCP PHASE1:Hg19::chr2:134432699..134432711,-#_a38494a90217e9d624f638ca288d54b6p@chr2:134432699..134432711, -
3.25e-19FFCP PHASE2:Hg19::chr3:100539939..100539944,-#_9b0ef131f0e90d1e342a7150bb7676a6p@chr3:100539939..100539944, -
3.25e-19FFCP PHASE1:Hg19::chr3:100539939..100539944,-#_9b0ef131f0e90d1e342a7150bb7676a6p@chr3:100539939..100539944, -
3.91e-19FFCP PHASE2:Hg19::chr1:152412443..152412445,+#_9cb4a2abafd92907f92422ca0f878c59p@chr1:152412443..152412445, +
3.91e-19FFCP PHASE1:Hg19::chr1:152412443..152412445,+#_9cb4a2abafd92907f92422ca0f878c59p@chr1:152412443..152412445, +
4.69e-19FFCP PHASE2:Hg19::chr12:104645296..104645338,+#_b618505f946f2ce636a76e8d232f6db4p11@TXNRD1
4.69e-19FFCP PHASE1:Hg19::chr12:104645296..104645338,+#_b618505f946f2ce636a76e8d232f6db4p11@TXNRD1
5.62e-19FFCP PHASE1:Hg19::chr12:96199635..96199641,-#_4d3380ab633a8be6e23c89173408ba56p@chr12:96199635..96199641, -
5.62e-19FFCP PHASE2:Hg19::chr12:96199635..96199641,-#_4d3380ab633a8be6e23c89173408ba56p@chr12:96199635..96199641, -
3.16e-18FFCP PHASE2:Hg19::chr7:41729687..41729699,-#_1405ee799e1c1d4227338e74317ffc44p15@INHBA
3.16e-18FFCP PHASE1:Hg19::chr7:41729687..41729699,-#_1405ee799e1c1d4227338e74317ffc44p15@INHBA
3.75e-18FFCP PHASE1:Hg19::chr15:68655572..68655579,-#_b6eff708e5537003835de7bdf9975f56p@chr15:68655572..68655579, -
3.75e-18FFCP PHASE2:Hg19::chr15:68655572..68655579,-#_b6eff708e5537003835de7bdf9975f56p@chr15:68655572..68655579, -
4.44e-18FFCP PHASE1:Hg19::chr5:14145555..14145567,-#_d78cbeeea86b5d75b7faa7ba94f32ac1p@chr5:14145555..14145567, -
4.44e-18FFCP PHASE2:Hg19::chr5:14145555..14145567,-#_d78cbeeea86b5d75b7faa7ba94f32ac1p@chr5:14145555..14145567, -
5.26e-18FFCP PHASE2:Hg19::chr9:119164050..119164076,+#_c1a22b1bd3b81efd7402cd3a549e24bep@chr9:119164050..119164076, +
5.26e-18FFCP PHASE1:Hg19::chr9:119164050..119164076,+#_c1a22b1bd3b81efd7402cd3a549e24bep@chr9:119164050..119164076, +
6.23e-18FFCP PHASE1:Hg19::chr11:27723059..27723067,-#_4e1ffc6496dc5141cdd8b9a76b5730aep11@BDNF
6.23e-18FFCP PHASE2:Hg19::chr11:27723059..27723067,-#_4e1ffc6496dc5141cdd8b9a76b5730aep11@BDNF
7.37e-18FFCP PHASE1:Hg19::chr8:106489489..106489493,+#_19349b1137cfcc0bffcfd3ae3a955238p@chr8:106489489..106489493, +
7.37e-18FFCP PHASE2:Hg19::chr8:106489489..106489493,+#_19349b1137cfcc0bffcfd3ae3a955238p@chr8:106489489..106489493, +
8.72e-18FFCP PHASE1:Hg19::chr2:134325832..134325855,-#_77c950f5c7185aa98e9b96c7e777b14cp7@NCKAP5
8.72e-18FFCP PHASE2:Hg19::chr2:134325832..134325855,-#_77c950f5c7185aa98e9b96c7e777b14cp7@NCKAP5
1.03e-17FFCP PHASE2:Hg19::chr13:38145589..38145600,-#_9f1d254dba5c23bca49a6b46f6b9a7b9p12@POSTN
1.03e-17FFCP PHASE1:Hg19::chr13:38145589..38145600,-#_9f1d254dba5c23bca49a6b46f6b9a7b9p12@POSTN
1.22e-17FFCP PHASE1:Hg19::chr9:119131199..119131210,+#_73bfe40815a75ef63ab7a028bb376064p@chr9:119131199..119131210, +
1.22e-17FFCP PHASE1:Hg19::chr3:159943174..159943185,+#_73bfe40815a75ef63ab7a028bb376064p7@C3orf80
1.22e-17FFCP PHASE1:Hg19::chr6:150185105..150185119,-#_73bfe40815a75ef63ab7a028bb376064p5@LRP11
1.22e-17FFCP PHASE2:Hg19::chr3:159943174..159943185,+#_73bfe40815a75ef63ab7a028bb376064p7@C3orf80
1.22e-17FFCP PHASE2:Hg19::chr9:119131199..119131210,+#_73bfe40815a75ef63ab7a028bb376064p@chr9:119131199..119131210, +
1.22e-17FFCP PHASE2:Hg19::chr6:150185105..150185119,-#_73bfe40815a75ef63ab7a028bb376064p5@LRP11
1.7e-17FFCP PHASE1:Hg19::chr3:193855009..193855029,+#_520e1cba074acb6e900f2b144a46c495p@chr3:193855009..193855029, +
1.7e-17FFCP PHASE2:Hg19::chr3:193855009..193855029,+#_520e1cba074acb6e900f2b144a46c495p@chr3:193855009..193855029, +
4.72e-17FFCP PHASE1:Hg19::chr2:217537210..217537213,-#_f3e0e250b19b5bb7cf8324d00de28b7cp54@IGFBP5
4.72e-17FFCP PHASE2:Hg19::chr2:217537210..217537213,-#_f3e0e250b19b5bb7cf8324d00de28b7cp54@IGFBP5
5.53e-17FFCP PHASE2:Hg19::chr12:47497443..47497474,+#_cac71162391ba537b411e15822756e3ap@chr12:47497443..47497474, +
5.53e-17FFCP PHASE1:Hg19::chr12:47497443..47497474,+#_cac71162391ba537b411e15822756e3ap@chr12:47497443..47497474, +
6.47e-17FFCP PHASE1:Hg19::chr4:7844024..7844029,-#_c1f4f6dcabf876202b644440e96bf18ap@chr4:7844024..7844029, -
6.47e-17FFCP PHASE2:Hg19::chr4:7844024..7844029,-#_c1f4f6dcabf876202b644440e96bf18ap@chr4:7844024..7844029, -

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