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Coexpression cluster:C943

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Full id: C943_Mesenchymal_Preadipocyte_Fibroblast_Adipocyte_Synoviocyte_Hair_Mesothelial



Phase1 CAGE Peaks

  Short description
Hg19::chr3:13590619..13590632,+ p2@FBLN2
Hg19::chr3:13590636..13590667,+ p1@FBLN2
Hg19::chr3:13612049..13612061,+ p@chr3:13612049..13612061
+
Hg19::chr3:13612234..13612246,+ p@chr3:13612234..13612246
+
Hg19::chr3:13612256..13612291,+ p@chr3:13612256..13612291
+
Hg19::chr3:13612325..13612337,+ p@chr3:13612325..13612337
+
Hg19::chr3:13612343..13612379,+ p@chr3:13612343..13612379
+
Hg19::chr3:13612408..13612437,+ p@chr3:13612408..13612437
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Hg19::chr3:13670704..13670708,+ p@chr3:13670704..13670708
+


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
fibroblast8.51e-1776
preadipocyte1.50e-1112
fat cell2.00e-1115
skin fibroblast2.04e-0823
cardiocyte7.58e-0716
Uber Anatomy
Ontology termp-valuen
primary circulatory organ4.55e-1227
heart6.63e-1224
primitive heart tube6.63e-1224
primary heart field6.63e-1224
anterior lateral plate mesoderm6.63e-1224
heart tube6.63e-1224
heart primordium6.63e-1224
cardiac mesoderm6.63e-1224
cardiogenic plate6.63e-1224
heart rudiment6.63e-1224
integument9.34e-1146
integumental system9.34e-1146
adipose tissue1.43e-1014
omentum6.70e-086
peritoneum6.70e-086
abdominal cavity6.70e-086
visceral peritoneum6.70e-086
skin of body1.33e-0741
blood vessel layer3.76e-077
surface structure6.87e-0799
splanchnic layer of lateral plate mesoderm8.77e-0783


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.16.05151
MA0004.11.06719
MA0006.12.89341
MA0007.11.81613
MA0009.10.870971
MA0014.11.14942
MA0017.10.301634
MA0019.10.558663
MA0024.10.766783
MA0025.11.00397
MA0027.12.48103
MA0028.10.280275
MA0029.10.785955
MA0030.10.774581
MA0031.10.710608
MA0038.10.514558
MA0040.10.791764
MA0041.10.433167
MA0042.10.402577
MA0043.10.871285
MA0046.10.860127
MA0048.10.559235
MA0050.10.403421
MA0051.10.510444
MA0052.10.795605
MA0055.10.22215
MA0056.10
MA0057.10.539841
MA0058.11.56347
MA0059.13.26849
MA0060.10.162248
MA0061.10.139804
MA0063.10
MA0066.10.514973
MA0067.11.18766
MA0068.10.109867
MA0069.10.856287
MA0070.10.845142
MA0071.10.47692
MA0072.10.840664
MA0073.10.00178726
MA0074.11.27017
MA0076.10.339975
MA0077.10.832987
MA0078.10.607575
MA0081.10.324031
MA0083.10.878452
MA0084.11.37471
MA0087.10.838229
MA0088.10.158781
MA0089.10
MA0090.10.353576
MA0091.10.417885
MA0092.10.993944
MA0093.12.08959
MA0095.10
MA0098.10
MA0100.10.528088
MA0101.10.271368
MA0103.11.31682
MA0105.10.0643619
MA0106.10.554855
MA0107.10.205358
MA0108.20.707575
MA0109.10
MA0111.10.366362
MA0113.12.39359
MA0114.10.200901
MA0115.11.11137
MA0116.10.208403
MA0117.10.908433
MA0119.10.83188
MA0122.10.934245
MA0124.11.06995
MA0125.10.986127
MA0130.10
MA0131.10.625452
MA0132.10
MA0133.10
MA0135.10.90122
MA0136.10.521435
MA0139.14.07339
MA0140.10.474342
MA0141.10.322254
MA0142.10.679161
MA0143.10.571113
MA0144.10.1885
MA0145.10.39929
MA0146.12.13659
MA0147.19.31123
MA0148.10.439278
MA0149.10.464973
MA0062.20.135498
MA0035.20.473658
MA0039.20.199243
MA0138.22.51613
MA0002.20.152495
MA0137.20.28622
MA0104.29.38345
MA0047.20.542971
MA0112.20.166662
MA0065.20.182082
MA0150.10.919271
MA0151.10
MA0152.10.480711
MA0153.10.969315
MA0154.10.488402
MA0155.11.00468
MA0156.10.288314
MA0157.10.652111
MA0158.10
MA0159.10.212043
MA0160.10.453945
MA0161.10
MA0162.10.294626
MA0163.10.034916
MA0164.10.583138
MA0080.20.268439
MA0018.20.556211
MA0099.20.481058
MA0079.20.893499
MA0102.21.41188
MA0258.10.180288
MA0259.11.82941
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
CTCF#1066463.573504248716680.002103883629372150.0121665283703211
RAD21#588566.903355930304225.2568380699896e-050.000893585467434317



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.