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MCL coexpression mm9:1978

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Phase1 CAGE Peaks

  Short description
Mm9::chr11:61191808..61191849,- p2@Slc47a1
Mm9::chr13:93616609..93616624,+ p@chr13:93616609..93616624
+
Mm9::chr9:46048823..46048828,+ p4@Apoa4
Mm9::chr9:46048865..46048876,+ p3@Apoa4


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0006855multidrug transport0.00588879748364596
GO:0030300regulation of cholesterol absorption0.00588879748364596
GO:0030299cholesterol absorption0.00588879748364596
GO:0044241lipid digestion0.00588879748364596
GO:0042627chylomicron0.00659509178698858
GO:0050892intestinal absorption0.00706578256317182
GO:0015893drug transport0.00732647433950719
GO:0022600digestive system process0.00732647433950719
GO:0015238drug transporter activity0.00732647433950719
GO:0042493response to drug0.0141234337457087
GO:0015297antiporter activity0.0156884018441022
GO:0007586digestion0.0156884018441022
GO:0005319lipid transporter activity0.0166511017120968
GO:0042157lipoprotein metabolic process0.0191533287968437
GO:0006869lipid transport0.0231971854661205
GO:0006810transport0.0408473186988738
GO:0051234establishment of localization0.0408473186988738
GO:0015291secondary active transmembrane transporter activity0.0458476782780808
GO:0051179localization0.04657740421181



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Uber Anatomy
Ontology termp-valuen
intestine3.14e-2631
gastrointestinal system2.13e-2147
mucosa4.65e-1615
digestive system9.55e-15116
digestive tract9.55e-15116
primitive gut9.55e-15116
endoderm-derived structure3.07e-14118
endoderm3.07e-14118
presumptive endoderm3.07e-14118
intestinal mucosa4.27e-1413
anatomical wall4.27e-1413
wall of intestine4.27e-1413
gastrointestinal system mucosa4.27e-1413
subdivision of digestive tract2.20e-13114
epithelium of mucosa5.33e-109
gastrointestinal system epithelium5.33e-109
intestinal epithelium5.33e-109
liver5.44e-1022
epithelial sac5.44e-1022
digestive gland5.44e-1022
epithelium of foregut-midgut junction5.44e-1022
anatomical boundary5.44e-1022
hepatobiliary system5.44e-1022
foregut-midgut junction5.44e-1022
hepatic diverticulum5.44e-1022
liver primordium5.44e-1022
septum transversum5.44e-1022
liver bud5.44e-1022
digestive tract diverticulum2.33e-0923
sac2.33e-0923
simple columnar epithelium3.17e-0911
organ component layer2.57e-0824
exocrine gland2.98e-0825
exocrine system2.98e-0825
gut epithelium5.83e-0755


TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0356887
MA0004.10.6888
MA0006.10.497533
MA0007.10.672186
MA0009.11.15569
MA0014.10.0809287
MA0017.10.528196
MA0019.10.964875
MA0024.11.11019
MA0025.11.39562
MA0027.12.81824
MA0028.10.509589
MA0029.11.08753
MA0030.11.09438
MA0031.11.05719
MA0038.10.846479
MA0040.11.16866
MA0041.11.47002
MA0042.10.589368
MA0043.11.25564
MA0046.11.1929
MA0048.10.266382
MA0050.10.731539
MA0051.10.856094
MA0052.11.17701
MA0055.10.125758
MA0056.10
MA0057.10.251896
MA0058.11.4226
MA0059.11.45189
MA0060.10.403071
MA0061.11.11761
MA0063.10
MA0066.10.834648
MA0067.11.50873
MA0068.10.256913
MA0069.11.17737
MA0070.11.16732
MA0071.10.73062
MA0072.11.15853
MA0073.10.00221226
MA0074.10.795862
MA0076.10.550092
MA0077.11.13603
MA0078.10.891476
MA0081.10.621611
MA0083.11.25482
MA0084.11.84013
MA0087.11.21037
MA0088.10.201215
MA0089.10
MA0090.10.650768
MA0091.10.703314
MA0092.10.651119
MA0093.11.29026
MA0095.10
MA0098.10
MA0100.10.783305
MA0101.10.605676
MA0103.10.540576
MA0105.10.841866
MA0106.10.899777
MA0107.10.533522
MA0108.20.989014
MA0109.10
MA0111.11.60035
MA0113.10.869608
MA0114.10.43587
MA0115.11.25852
MA0116.10.497293
MA0117.11.22527
MA0119.11.47447
MA0122.11.24573
MA0124.11.45461
MA0125.11.37907
MA0130.10
MA0131.10.960068
MA0132.10
MA0133.10
MA0135.11.29308
MA0136.10.817395
MA0139.10.365453
MA0140.10.78318
MA0141.10.563066
MA0142.11.04199
MA0143.10.887119
MA0144.10.439506
MA0145.10.21199
MA0146.10.647546
MA0147.10.453952
MA0148.10.706718
MA0149.10.611881
MA0062.20.319836
MA0035.20.788288
MA0039.20.0959929
MA0138.20.951653
MA0002.20.368961
MA0137.20.559766
MA0104.20.386166
MA0047.20.845655
MA0112.20.211985
MA0065.21.14711
MA0150.10.67206
MA0151.10
MA0152.10.84577
MA0153.11.31015
MA0154.10.263609
MA0155.10.230016
MA0156.10.549102
MA0157.11.0083
MA0158.10
MA0159.10.465802
MA0160.10.71003
MA0161.10
MA0162.10.10667
MA0163.10.0996272
MA0164.10.817786
MA0080.20.534538
MA0018.20.828253
MA0099.20.944966
MA0079.20.000201415
MA0102.21.8929
MA0258.10.419871
MA0259.10.441366
MA0442.10