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{{UBERON
{{UBERON
|id=UBERON:0001049
|alt_id=UBERON:FBbt_00005554-MIAA_0000069-ZFA_0001135
|name=neural tube
|namespace=
|def="In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." [Wikipedia:Neural_tube]
|xref=AAO:0010617;;BTO:0001057;;EHDAA2:0001254;;EHDAA:2869;;EHDAA:908;;EMAPA:16164;;EMAPA:16530;;EMAPA:16757;;http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png;;http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png;;MAT:0000069;;MIAA:0000069;;ncithesaurus:Neural_Tube;;SCTID:362852000;;TAO:0001135;;VHOG:0000307;;XAO:0003204;;ZFA:0001135
|is_a=UBERON:0000025;;UBERON:0002050;;UBERON:0004121
|synonym="presumptive central nervous system" RELATED [];;"tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube]
|comment=The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium[GO:0021915]
|comment=The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium[GO:0021915]
|alt_id=UBERON:FBbt_00005554-MIAA_0000069-ZFA_0001135
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." [Wikipedia:Neural_tube]
|subset=uberon_slim;;vertebrate_core
|derives_from=
|derives_from=
|develops_from=UBERON:0002346;;UBERON:0005068;;UBERON:0006241
|develops_from=UBERON:0005068
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0001049
|is_a=UBERON:0003914 ;;UBERON:0005291 ;;UBERON:0007497 ;;UBERON:0010371 ;;UBERON:0016879
|is_obsolete=
|located_in=
|located_in=
|name=neural tube
|namespace=
|obo_creation_date=
|part_of=UBERON:0000922;;UBERON:0001016
|part_of=UBERON:0000922;;UBERON:0001016
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.[AAO]" xsd:string
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.[AAO]" xsd:string
|is_obsolete=
|subset=uberon_slim;;vertebrate_core
|preceded_by=
|synonym="presumptive central nervous system" RELATED [];;"tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube]
|union_of=
|xref=AAO:0010617;;BTO:0001057;;EHDAA2:0001254;;EHDAA:2869;;EHDAA:908;;EMAPA:16164;;EMAPA:16530;;EMAPA:16757;;http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png;;http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png;;MAT:0000069;;MIAA:0000069;;ncithesaurus:Neural_Tube;;SCTID:362852000;;TAO:0001135;;VHOG:0000307;;XAO:0003204;;ZFA:0001135
}}
}}

Revision as of 11:00, 12 September 2014

Name:neural tube
Definition:"In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." [Wikipedia:Neural_tube]
Xrefs:
links:

AAO:0010617
BTO:0001057
EHDAA2:0001254
EHDAA:2869
EHDAA:908
EMAPA:16164
EMAPA:16530
EMAPA:16757
[ Gray19_with_color.png Gray19_with_color.png]
[ 200px-Gray19_with_color.png 200px-Gray19_with_color.png]
MAT:0000069
MIAA:0000069
ncithesaurus:Neural_Tube
SCTID:362852000
TAO:0001135
VHOG:0000307
XAO:0003204

ZFA:0001135
Synonyms: "presumptive central nervous system" RELATED []
"tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube]
Comments:The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium[GO:0021915]
Alt_id: UBERON:FBbt_00005554-MIAA_0000069-ZFA_0001135
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0003914(epithelial tube),UBERON:0005291(embryonic tissue),UBERON:0007497(developing epithelial placode),UBERON:0010371(ecto-epithelium),UBERON:0016879(future central nervous system)
develops_from:UBERON:0005068(neural rod)
part_of:UBERON:0000922(embryo),UBERON:0001016(nervous system)



Children

part of:UBERON:0003076 (posterior neural tube),UBERON:0003080 (anterior neural tube),UBERON:0004061 (neural tube mantle layer)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology



Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001049 (neural tube), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
9.5e-145FFCP PHASE2:Hg19::chr12:106976678..106976708,+#_725484deac15eaa116bd162f6b367a9bp2@RFX4
9.5e-145FFCP PHASE1:Hg19::chr12:106976678..106976708,+#_725484deac15eaa116bd162f6b367a9bp2@RFX4
4.41e-144FFCP PHASE2:Hg19::chr5:87439352..87439386,-#_6205c941bd6ee79eb295023de1c76a5fp@chr5:87439352..87439386, -
4.41e-144FFCP PHASE1:Hg19::chr5:87439352..87439386,-#_6205c941bd6ee79eb295023de1c76a5fp@chr5:87439352..87439386, -
5.06e-144FFCP PHASE1:Hg19::chr2:74612644..74612670,+#_150803d0f45a81392e302f85fbf6e1fbp1@ENST00000412957
5.06e-144FFCP PHASE2:Hg19::chr2:74612644..74612670,+#_150803d0f45a81392e302f85fbf6e1fbp1@ENST00000412957
1.1e-143FFCP PHASE2:Hg19::chr5:11588907..11588967,-#_896b1704c2b70683f771642673988a85p3@CTNND2
1.1e-143FFCP PHASE1:Hg19::chr5:11588907..11588967,-#_896b1704c2b70683f771642673988a85p3@CTNND2
1.17e-142FFCP PHASE2:Hg19::chr4:46126063..46126087,-#_951d27ee98e227f1adbe994d76b82a3ep2@GABRG1
1.17e-142FFCP PHASE1:Hg19::chr4:46126063..46126087,-#_951d27ee98e227f1adbe994d76b82a3ep2@GABRG1
2.68e-142FFCP PHASE2:Hg19::chr2:50201220..50201261,-#_2994e02b49197a40a1f90466d7972438p3@NRXN1
2.68e-142FFCP PHASE1:Hg19::chr2:50201220..50201261,-#_2994e02b49197a40a1f90466d7972438p3@NRXN1
1.04e-141FFCP PHASE1:Hg19::chr5:112074041..112074101,+#_5340d165fec2300eb103c0e974a10470p4@APC
1.04e-141FFCP PHASE2:Hg19::chr5:112074041..112074101,+#_5340d165fec2300eb103c0e974a10470p4@APC
1.18e-141FFCP PHASE2:Hg19::chr5:11384884..11384916,-#_c08c75eaefb61ae89071fda01a641de2p8@CTNND2
1.18e-141FFCP PHASE1:Hg19::chr5:11384884..11384916,-#_c08c75eaefb61ae89071fda01a641de2p8@CTNND2
7.98e-141FFCP PHASE1:Hg19::chr18:32398296..32398318,+#_8b05eeec485f6c3bea00cb5727700a15p7@DTNA
7.98e-141FFCP PHASE2:Hg19::chr18:32398296..32398318,+#_8b05eeec485f6c3bea00cb5727700a15p7@DTNA
1.0e-140FFCP PHASE2:Hg19::chr17:68101117..68101162,+#_d6230af70c7103ae10deea46e5921649p2@KCNJ16
1.0e-140FFCP PHASE1:Hg19::chr17:68101117..68101162,+#_d6230af70c7103ae10deea46e5921649p2@KCNJ16
2.58e-140FFCP PHASE1:Hg19::chr5:146314142..146314146,-#_a6f7c8e7709e5c3ff83bd7471eb4a3edp@chr5:146314142..146314146, -
2.58e-140FFCP PHASE2:Hg19::chr5:146314142..146314146,-#_a6f7c8e7709e5c3ff83bd7471eb4a3edp@chr5:146314142..146314146, -
1.46e-139FFCP PHASE1:Hg19::chr12:106976774..106976788,+#_a2fb22a931a0c1dbe7083ad39b7cf6a6p1@RFX4
1.46e-139FFCP PHASE2:Hg19::chr12:106976774..106976788,+#_a2fb22a931a0c1dbe7083ad39b7cf6a6p1@RFX4
9.16e-139FFCP PHASE2:Hg19::chr12:106976656..106976672,+#_4ae62a03baa2ad6359052368a8ac670dp4@RFX4
9.16e-139FFCP PHASE1:Hg19::chr12:106976656..106976672,+#_4ae62a03baa2ad6359052368a8ac670dp4@RFX4
1.47e-138FFCP PHASE2:Hg19::chr1:84630574..84630602,+#_2f0395a25ba4d26edc90f4c5e8e484d9p9@PRKACB
1.47e-138FFCP PHASE1:Hg19::chr1:84630574..84630602,+#_2f0395a25ba4d26edc90f4c5e8e484d9p9@PRKACB
4.62e-138FFCP PHASE2:Hg19::chr5:11386115..11386130,-#_b7d0245b3e780c52b0b010ec445be82bp2@CTNND2
4.62e-138FFCP PHASE1:Hg19::chr5:11386115..11386130,-#_b7d0245b3e780c52b0b010ec445be82bp2@CTNND2
1.71e-137FFCP PHASE2:Hg19::chr15:46702499..46702523,+#_fdc9f52388c1ef2da2d502e55b3bbc57p@chr15:46702499..46702523, +
1.71e-137FFCP PHASE1:Hg19::chr15:46702499..46702523,+#_fdc9f52388c1ef2da2d502e55b3bbc57p@chr15:46702499..46702523, +
5.75e-137FFCP PHASE1:Hg19::chr1:84630610..84630621,+#_7ba557b69570a62018f7e7c56d1f1393p17@PRKACB
5.75e-137FFCP PHASE2:Hg19::chr1:84630610..84630621,+#_7ba557b69570a62018f7e7c56d1f1393p17@PRKACB
6.55e-137FFCP PHASE2:Hg19::chr9:87283501..87283520,+#_742464c387f71e4d95a68fbd390ec9acp17@NTRK2
6.55e-137FFCP PHASE1:Hg19::chr9:87283501..87283520,+#_742464c387f71e4d95a68fbd390ec9acp17@NTRK2
8.93e-137FFCP PHASE2:Hg19::chr6:80131670..80131724,+#_dafad2b29915451b86634fe94337899ep@chr6:80131670..80131724, +
8.93e-137FFCP PHASE1:Hg19::chr6:80131670..80131724,+#_dafad2b29915451b86634fe94337899ep@chr6:80131670..80131724, +
2.51e-136FFCP PHASE1:Hg19::chr11:35441048..35441059,-#_befd43992c884ae320563739b2fdf617p4@SLC1A2
2.51e-136FFCP PHASE2:Hg19::chr11:35441048..35441059,-#_befd43992c884ae320563739b2fdf617p4@SLC1A2
2.84e-136FFCP PHASE2:Hg19::chr5:160279207..160279247,-#_5f5249dc67a16a5747fe0b43dd53d7bcp1@ATP10B
2.84e-136FFCP PHASE1:Hg19::chr5:160279207..160279247,-#_5f5249dc67a16a5747fe0b43dd53d7bcp1@ATP10B
3.14e-136FFCP PHASE2:Hg19::chr1:2005182..2005194,+#_1d6cb3b79f384287c53abc557e03b94cp8@PRKCZ
3.14e-136FFCP PHASE1:Hg19::chr1:2005182..2005194,+#_1d6cb3b79f384287c53abc557e03b94cp8@PRKCZ
4.26e-136FFCP PHASE2:Hg19::chrX:13835312..13835321,-#_bbcdf64156dfda359dcae1ed33f0ae0dp9@GPM6B
4.26e-136FFCP PHASE1:Hg19::chrX:13835312..13835321,-#_bbcdf64156dfda359dcae1ed33f0ae0dp9@GPM6B
5.24e-136FFCP PHASE2:Hg19::chr18:24443122..24443142,-#_4ba3c9f1f41093d8f1e21b78d03fc2bap5@AQP4
5.24e-136FFCP PHASE1:Hg19::chr18:24443122..24443142,-#_4ba3c9f1f41093d8f1e21b78d03fc2bap5@AQP4
5.54e-136FFCP PHASE2:Hg19::chr2:74612614..74612643,+#_e78201d198fe2984ca44ede42dd0b4edp1@ENST00000418990, p1@ENST00000426715, p1@ENST00000427343
5.54e-136FFCP PHASE1:Hg19::chr2:74612614..74612643,+#_e78201d198fe2984ca44ede42dd0b4edp1@ENST00000418990, p1@ENST00000426715, p1@ENST00000427343
9.78e-136FFCP PHASE1:Hg19::chr6:56716896..56716928,-#_1d6fa6f6105f02c79ce3a3eca81902cbp8@DST
9.78e-136FFCP PHASE2:Hg19::chr6:56716896..56716928,-#_1d6fa6f6105f02c79ce3a3eca81902cbp8@DST
1.52e-135FFCP PHASE1:Hg19::chr7:47420733..47420758,-#_5c1810a369164725e98d8c1d4235cf32p@chr7:47420733..47420758, -
1.52e-135FFCP PHASE2:Hg19::chr7:47420733..47420758,-#_5c1810a369164725e98d8c1d4235cf32p@chr7:47420733..47420758, -
2.32e-135FFCP PHASE1:Hg19::chr17:54230819..54230848,+#_0cc049a390aba02b47efe7d323d7b0fap1@ANKFN1
2.32e-135FFCP PHASE2:Hg19::chr17:54230819..54230848,+#_0cc049a390aba02b47efe7d323d7b0fap1@ANKFN1
3.21e-135FFCP PHASE1:Hg19::chr4:46126009..46126045,-#_6fbfa49880f516cfa91d7014785a2393p1@GABRG1
3.21e-135FFCP PHASE2:Hg19::chr4:46126009..46126045,-#_6fbfa49880f516cfa91d7014785a2393p1@GABRG1
5.25e-135FFCP PHASE1:Hg19::chr17:7558857..7558903,+#_1f7a08ebfd2a94575c36b49403eedf8ap@chr17:7558857..7558903, +
5.25e-135FFCP PHASE2:Hg19::chr17:7558857..7558903,+#_1f7a08ebfd2a94575c36b49403eedf8ap@chr17:7558857..7558903, +
8.03e-135FFCP PHASE1:Hg19::chr2:73286253..73286279,-#_751b0deccc131a65ac7fec494a15e117p3@SFXN5
8.03e-135FFCP PHASE2:Hg19::chr2:73286253..73286279,-#_751b0deccc131a65ac7fec494a15e117p3@SFXN5
1.91e-134FFCP PHASE1:Hg19::chr4:46126093..46126106,-#_657175530c551e22c91aa6cedcea8074p3@GABRG1
1.91e-134FFCP PHASE2:Hg19::chr4:46126093..46126106,-#_657175530c551e22c91aa6cedcea8074p3@GABRG1
2.97e-134FFCP PHASE2:Hg19::chr18:32398400..32398416,+#_2ccbde772d4a8aaed71d98122adf83a8p10@DTNA
2.97e-134FFCP PHASE1:Hg19::chr18:32398400..32398416,+#_2ccbde772d4a8aaed71d98122adf83a8p10@DTNA
4.25e-134FFCP PHASE2:Hg19::chr18:32398372..32398394,+#_9c728485c2a60796cac03dbbcf72a502p5@DTNA
4.25e-134FFCP PHASE1:Hg19::chr18:32398372..32398394,+#_9c728485c2a60796cac03dbbcf72a502p5@DTNA
4.84e-134FFCP PHASE1:Hg19::chr17:42989121..42989166,-#_16b2b168d7d33fd7cd6be1e521226153p7@GFAP
4.84e-134FFCP PHASE2:Hg19::chr17:42989121..42989166,-#_16b2b168d7d33fd7cd6be1e521226153p7@GFAP
5.15e-134FFCP PHASE1:Hg19::chr1:156217805..156217817,-#_195d7a8e905bf419ac3ccc1a4329d76ap2@PAQR6
5.15e-134FFCP PHASE2:Hg19::chr1:156217805..156217817,-#_195d7a8e905bf419ac3ccc1a4329d76ap2@PAQR6
1.37e-133FFCP PHASE1:Hg19::chr16:72459772..72459794,+#_d1c4238f61dec8a7d18b6d3b01a8cb2dp2@uc002fch.1
1.37e-133FFCP PHASE2:Hg19::chr16:72459772..72459794,+#_d1c4238f61dec8a7d18b6d3b01a8cb2dp2@uc002fch.1
1.42e-133FFCP PHASE2:Hg19::chr17:36760961..36760976,-#_45af57664f4df938683e6ebf7bd09d46p2@SRCIN1
1.42e-133FFCP PHASE1:Hg19::chr17:36760961..36760976,-#_45af57664f4df938683e6ebf7bd09d46p2@SRCIN1
1.45e-133FFCP PHASE1:Hg19::chr3:153838982..153839001,-#_6ceb886b4c8c222ad4b56c13c99e0252p4@ARHGEF26-AS1
1.45e-133FFCP PHASE2:Hg19::chr3:153838982..153839001,-#_6ceb886b4c8c222ad4b56c13c99e0252p4@ARHGEF26-AS1
2.38e-133FFCP PHASE2:Hg19::chr12:41221684..41221704,+#_6ee567a5af1e6bc9c2978249e9ef7d6fp5@CNTN1
2.38e-133FFCP PHASE1:Hg19::chr12:41221684..41221704,+#_6ee567a5af1e6bc9c2978249e9ef7d6fp5@CNTN1
2.91e-133FFCP PHASE1:Hg19::chr5:11384929..11384947,-#_2448342798cc4cad51aa4f9cd65f82acp15@CTNND2
2.91e-133FFCP PHASE2:Hg19::chr5:11384929..11384947,-#_2448342798cc4cad51aa4f9cd65f82acp15@CTNND2
3.31e-133FFCP PHASE1:Hg19::chr12:57980138..57980165,+#_14af37d44e9ebb3af620c8125c2cb633p3@KIF5A
3.31e-133FFCP PHASE2:Hg19::chr12:57980138..57980165,+#_14af37d44e9ebb3af620c8125c2cb633p3@KIF5A
3.45e-133FFCP PHASE2:Hg19::chr1:110082487..110082535,+#_9b29b22ce168a006d00e8840fed112b7p1@GPR61
3.45e-133FFCP PHASE1:Hg19::chr1:110082487..110082535,+#_9b29b22ce168a006d00e8840fed112b7p1@GPR61
1.11e-132FFCP PHASE2:Hg19::chr8:63161215..63161235,+#_c1695ae8b563e345418fe71c47d97945p5@NKAIN3
1.11e-132FFCP PHASE1:Hg19::chr8:63161215..63161235,+#_c1695ae8b563e345418fe71c47d97945p5@NKAIN3
1.25e-132FFCP PHASE2:Hg19::chr15:30261066..30261096,-#_0321d44e9cc54f1fe8f2d376d1317455p12@TJP1
1.25e-132FFCP PHASE1:Hg19::chr15:30261066..30261096,-#_0321d44e9cc54f1fe8f2d376d1317455p12@TJP1
1.94e-132FFCP PHASE2:Hg19::chr17:7560542..7560578,+#_b3c9f582c0ea45fba0d5f0e1004afcecp4@ATP1B2
1.94e-132FFCP PHASE1:Hg19::chr17:7560542..7560578,+#_b3c9f582c0ea45fba0d5f0e1004afcecp4@ATP1B2
2.17e-132FFCP PHASE2:Hg19::chr7:29519599..29519612,+#_2c737b9815b42d86df83b7de06a7d3aap9@CHN2
2.17e-132FFCP PHASE1:Hg19::chr7:29519599..29519612,+#_2c737b9815b42d86df83b7de06a7d3aap9@CHN2
2.85e-132FFCP PHASE2:Hg19::chr12:102060112..102060135,+#_a77b16be2520deefab2ce6301dafd43ap4@MYBPC1
2.85e-132FFCP PHASE1:Hg19::chr12:102060112..102060135,+#_a77b16be2520deefab2ce6301dafd43ap4@MYBPC1
3.19e-132FFCP PHASE2:Hg19::chr5:87437100..87437115,-#_1d9af7d3f2c267e3b46c4b05b6615627p1@LOC100289347
3.19e-132FFCP PHASE1:Hg19::chr5:87437100..87437115,-#_1d9af7d3f2c267e3b46c4b05b6615627p1@LOC100289347
4.04e-132FFCP PHASE2:Hg19::chr2:210526233..210526258,+#_ae0f2c5cc641942271cf756c26ffb30cp9@MAP2
4.04e-132FFCP PHASE1:Hg19::chr2:210526233..210526258,+#_ae0f2c5cc641942271cf756c26ffb30cp9@MAP2










Property "Property value" (as page type) with input value "UBPROP:0000001 "Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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