MCL coexpression mm9:901

Phase1 CAGE Peaks

	Short description
Mm9::chr11:34108085..34108092,-	p1@Foxi1
Mm9::chr11:96156719..96156721,-	p@chr11:96156719..96156721 -
Mm9::chr2:74975548..74975563,-	p1@ENSMUST00000143898
Mm9::chr7:81210431..81210442,-	p@chr7:81210431..81210442 -
Mm9::chr7:86741445..86741455,-	p@chr7:86741445..86741455 -
Mm9::chr7:86741570..86741584,-	p@chr7:86741570..86741584 -
Mm9::chr7:86741766..86741778,-	p@chr7:86741766..86741778 -
Mm9::chr7:86762435..86762451,-	p1@Rhcg

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0015696	ammonium transport	0.0140239391447833
GO:0008519	ammonium transmembrane transporter activity	0.0140239391447833
GO:0015695	organic cation transport	0.0140239391447833
GO:0015101	organic cation transmembrane transporter activity	0.0157760670721659

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
kidney	1.54e-19	14
kidney mesenchyme	1.54e-19	14
upper urinary tract	1.54e-19	14
kidney rudiment	1.54e-19	14
kidney field	1.54e-19	14
urinary system structure	1.83e-14	18
renal system	1.57e-13	19
cavitated compound organ	6.17e-12	21
male reproductive organ	1.71e-10	15
male organism	1.07e-09	16
male reproductive system	1.07e-09	16
testis	6.14e-09	14
gonad	3.10e-08	18
gonad primordium	3.10e-08	18
reproductive organ	4.13e-07	24
external genitalia	4.82e-07	17
indifferent external genitalia	4.82e-07	17
indifferent gonad	4.82e-07	17
epididymis	9.96e-07	3
excretory tube	9.96e-07	3
mesonephric epithelium	9.96e-07	3
mesonephric tubule	9.96e-07	3
nephric duct	9.96e-07	3
kidney epithelium	9.96e-07	3
renal duct	9.96e-07	3
mesonephric duct	9.96e-07	3
pronephric duct	9.96e-07	3

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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