MCL coexpression mm9:225: Difference between revisions
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|ontology_enrichment_uberon=UBERON:0000026!1.45e-15!12;UBERON:0004708!1.45e-15!12;UBERON:0002101!1.45e-15!12;UBERON:0004357!1.45e-15!12;UBERON:0004347!1.45e-15!12;UBERON:0005732!1.45e-15!12;UBERON:0005733!1.45e-15!12;UBERON:0010707!4.52e-14!13;UBERON:0003102!4.80e-12!22;UBERON:0002102!1.43e-09!7;UBERON:0004710!1.43e-09!7;UBERON:0005419!1.43e-09!7;UBERON:0005417!1.43e-09!7;UBERON:0005729!1.43e-09!7;UBERON:0010708!3.63e-08!8;UBERON:0000075!5.86e-08!6;UBERON:0005856!5.86e-08!6;UBERON:0005866!5.86e-08!6;UBERON:0005863!5.86e-08!6;UBERON:0005418!1.64e-07!5;UBERON:0002472!1.64e-07!5;UBERON:0008784!1.64e-07!5;UBERON:0006058!1.64e-07!5;UBERON:0004709!1.64e-07!5;UBERON:0002529!1.64e-07!5;UBERON:0010538!1.64e-07!5;UBERON:0005420!1.64e-07!5;UBERON:0010758!1.64e-07!5;UBERON:0000978!1.64e-07!5;UBERON:0002103!1.64e-07!5;UBERON:0000376!1.64e-07!5;UBERON:0000154!1.64e-07!5;UBERON:0010709!1.64e-07!5;UBERON:0005730!1.64e-07!5 | |ontology_enrichment_uberon=UBERON:0000026!1.45e-15!12;UBERON:0004708!1.45e-15!12;UBERON:0002101!1.45e-15!12;UBERON:0004357!1.45e-15!12;UBERON:0004347!1.45e-15!12;UBERON:0005732!1.45e-15!12;UBERON:0005733!1.45e-15!12;UBERON:0010707!4.52e-14!13;UBERON:0003102!4.80e-12!22;UBERON:0002102!1.43e-09!7;UBERON:0004710!1.43e-09!7;UBERON:0005419!1.43e-09!7;UBERON:0005417!1.43e-09!7;UBERON:0005729!1.43e-09!7;UBERON:0010708!3.63e-08!8;UBERON:0000075!5.86e-08!6;UBERON:0005856!5.86e-08!6;UBERON:0005866!5.86e-08!6;UBERON:0005863!5.86e-08!6;UBERON:0005418!1.64e-07!5;UBERON:0002472!1.64e-07!5;UBERON:0008784!1.64e-07!5;UBERON:0006058!1.64e-07!5;UBERON:0004709!1.64e-07!5;UBERON:0002529!1.64e-07!5;UBERON:0010538!1.64e-07!5;UBERON:0005420!1.64e-07!5;UBERON:0010758!1.64e-07!5;UBERON:0000978!1.64e-07!5;UBERON:0002103!1.64e-07!5;UBERON:0000376!1.64e-07!5;UBERON:0000154!1.64e-07!5;UBERON:0010709!1.64e-07!5;UBERON:0005730!1.64e-07!5 | ||
|tfbs_overrepresentation_for_novel_motifs=0.038675,0.632605,0.303794,0.0521344,0.739175,0.458442,0.316055,1.05547,1.4481,2.01651,0.262044,0.300876,0.553961,0.101135,0.813138,0,0.21295,0.127982,0.314208,0.543703,0.243179,0.440927,0.330636,0.0491323,0.316915,0.368158,0.16649,1.80884,0.0168238,0.281975,0.472306,0.283652,1.72233,0.369199,2.41275,3.25805,0.24095,0.616866,0.357102,0.0210063,0.272539,0.222116,0.172548,0.543344,0.457095,0.0483533,0.162636,0.250169,1.48029,0.95852,0.201485,0.404907,0.394991,0.392852,0.40698,0.341117,0.412875,0.0839337,0.411554,0.33845,0.26911,0.134246,0.654496,0.194216,0.355799,2.58955,0.521479,0.838102,0.73378,0.701582,0.272005,0.230324,0.150989,0.434495,0.241982,0.0207409,0.368913,0.920035,0.256849,0.101696,0.826984,0.224583,0.416055,0.341731,0.341929,0.220922,4.12353,0.428056,0.496452,0.992074,0.58241,0.345795,0.293074,1.08129,0.0881412,0.297551,0.210907,0.295154,0.162789,0.330179,0.241107,0.283447,0.378871,0.201872,0.201187,0.481919,0.241325,0.0698405,0.776826,0.0998343,0.337339,0.380295,0.0239112,0.2682,2.45105,0.463877,0.492871,0.197527,0.213814,0.4103,0.438969,0.180968,0.11583,0.155368,0.636966,0.719337,0.0991526,0.288075,0.520169,0.511075,0.957686,0.18602,0.494785,0.111453,0.60784,6.9299,0.0411839,0.223681,0.564325,1.34996,0.961602,0.525552,0.386957,0.291349,0.572722,1.26501,0.164504,1.31106,0.162069,0.284788,0.00397468,0.00422885,0.394118,0.171634,0.110984,0.46141,0.406306,0.17425,0.345623,0.159532,0.572691,0.341266,0.720067,0.143226,0.19487,0.707665,0.0398415,0.0889586,0.0136125 | |tfbs_overrepresentation_for_novel_motifs=0.038675,0.632605,0.303794,0.0521344,0.739175,0.458442,0.316055,1.05547,1.4481,2.01651,0.262044,0.300876,0.553961,0.101135,0.813138,0,0.21295,0.127982,0.314208,0.543703,0.243179,0.440927,0.330636,0.0491323,0.316915,0.368158,0.16649,1.80884,0.0168238,0.281975,0.472306,0.283652,1.72233,0.369199,2.41275,3.25805,0.24095,0.616866,0.357102,0.0210063,0.272539,0.222116,0.172548,0.543344,0.457095,0.0483533,0.162636,0.250169,1.48029,0.95852,0.201485,0.404907,0.394991,0.392852,0.40698,0.341117,0.412875,0.0839337,0.411554,0.33845,0.26911,0.134246,0.654496,0.194216,0.355799,2.58955,0.521479,0.838102,0.73378,0.701582,0.272005,0.230324,0.150989,0.434495,0.241982,0.0207409,0.368913,0.920035,0.256849,0.101696,0.826984,0.224583,0.416055,0.341731,0.341929,0.220922,4.12353,0.428056,0.496452,0.992074,0.58241,0.345795,0.293074,1.08129,0.0881412,0.297551,0.210907,0.295154,0.162789,0.330179,0.241107,0.283447,0.378871,0.201872,0.201187,0.481919,0.241325,0.0698405,0.776826,0.0998343,0.337339,0.380295,0.0239112,0.2682,2.45105,0.463877,0.492871,0.197527,0.213814,0.4103,0.438969,0.180968,0.11583,0.155368,0.636966,0.719337,0.0991526,0.288075,0.520169,0.511075,0.957686,0.18602,0.494785,0.111453,0.60784,6.9299,0.0411839,0.223681,0.564325,1.34996,0.961602,0.525552,0.386957,0.291349,0.572722,1.26501,0.164504,1.31106,0.162069,0.284788,0.00397468,0.00422885,0.394118,0.171634,0.110984,0.46141,0.406306,0.17425,0.345623,0.159532,0.572691,0.341266,0.720067,0.143226,0.19487,0.707665,0.0398415,0.0889586,0.0136125 | ||
|tfbs_overrepresentation_jaspar=MA0003.1;0.208917,MA0004.1;0.0523019,MA0006.1;0.307617,MA0007.1;0.178699,MA0009.1;0.30322,MA0014.1;0.376865,MA0017.1;0.368292,MA0019.1;0.177916,MA0024.1;0.745934,MA0025.1;0.490939,MA0027.1;1.84332,MA0028.1;0.0625976,MA0029.1;0.255531,MA0030.1;0.260188,MA0031.1;0.235297,MA0038.1;0.114851,MA0040.1;0.312625,MA0041.1;0.122365,MA0042.1;0.111518,MA0043.1;0.37807,MA0046.1;0.330453,MA0048.1;1.13075,MA0050.1;0.0666657,MA0051.1;0.119487,MA0052.1;0.318728,MA0055.1;0.60771,MA0056.1;0,MA0057.1;0.285369,MA0058.1;0.0249251,MA0059.1;0.0277969,MA0060.1;0.0678139,MA0061.1;0.840046,MA0063.1;0,MA0066.1;0.71687,MA0067.1;0.587517,MA0068.1;0.0237618,MA0069.1;0.318986,MA0070.1;0.311646,MA0071.1;0.507269,MA0072.1;0.823673,MA0073.1;1.23114,MA0074.1;0.307062,MA0076.1;0.0191324,MA0077.1;0.289168,MA0078.1;0.13731,MA0081.1;0.135744,MA0083.1;0.377437,MA0084.1;0.888928,MA0087.1;0.343502,MA0088.1;0.329408,MA0089.1;0,MA0090.1;1.01672,MA0091.1;1.20933,MA0092.1;0.366076,MA0093.1;0.0143916,MA0095.1;0,MA0098.1;0,MA0100.1;0.292642,MA0101.1;0.859809,MA0103.1;0.394121,MA0105.1;0.966856,MA0106.1;2.00021,MA0107.1;1.29817,MA0108.2;0.56139,MA0109.1;0,MA0111.1;0.391982,MA0113.1;0.126154,MA0114.1;1.13193,MA0115.1;0.380305,MA0116.1;0.307163,MA0117.1;0.354763,MA0119.1;0.295109,MA0122.1;0.370415,MA0124.1;1.33622,MA0125.1;1.20061,MA0130.1;0,MA0131.1;0.519826,MA0132.1;0,MA0133.1;0,MA0135.1;1.04987,MA0136.1;0.10138,MA0139.1;0.20766,MA0140.1;0.0866252,MA0141.1;0.719674,MA0142.1;0.225403,MA0143.1;0.135052,MA0144.1;0.206664,MA0145.1;0.379282,MA0146.1;0.0245201,MA0147.1;0.230012,MA0148.1;1.22213,MA0149.1;0.0314134,MA0062.2;0.000890599,MA0035.2;0.0887515,MA0039.2;0.458645,MA0138.2;0.170255,MA0002.2;0.548365,MA0137.2;0.228652,MA0104.2;0.131384,MA0047.2;1.21458,MA0112.2;1.64242,MA0065.2;1.94543,MA0150.1;0.0472137,MA0151.1;0,MA0152.1;0.114512,MA0153.1;0.42102,MA0154.1;0.654845,MA0155.1;0.834128,MA0156.1;0.0189666,MA0157.1;0.204086,MA0158.1;0,MA0159.1;0.11994,MA0160.1;0.214615,MA0161.1;0,MA0162.1;0.0685264,MA0163.1;0.893125,MA0164.1;0.332928,MA0080.2;0.0166373,MA0018.2;0.10631,MA0099.2;0.166437,MA0079.2;0.0104093,MA0102.2;0.938682,MA0258.1;0.321845,MA0259.1;0.0976349,MA0442.1;0 | |||
}} | }} |
Revision as of 11:23, 23 January 2013
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0005578 | proteinaceous extracellular matrix | 9.94805947125308e-09 |
GO:0005201 | extracellular matrix structural constituent | 9.94805947125308e-09 |
GO:0022610 | biological adhesion | 4.72297215510633e-07 |
GO:0007155 | cell adhesion | 4.72297215510633e-07 |
GO:0030198 | extracellular matrix organization and biogenesis | 6.55853841387458e-07 |
GO:0044420 | extracellular matrix part | 3.81878223203534e-06 |
GO:0043062 | extracellular structure organization and biogenesis | 4.39897247315514e-06 |
GO:0030020 | extracellular matrix structural constituent conferring tensile strength | 7.75836238883046e-06 |
GO:0005581 | collagen | 1.23252054246797e-05 |
GO:0005518 | collagen binding | 6.5611849078916e-05 |
GO:0044421 | extracellular region part | 6.68622318005401e-05 |
GO:0006817 | phosphate transport | 6.68622318005401e-05 |
GO:0001502 | cartilage condensation | 0.000108032930554557 |
GO:0030199 | collagen fibril organization | 0.000233644177338014 |
GO:0005540 | hyaluronic acid binding | 0.000249129426871181 |
GO:0006029 | proteoglycan metabolic process | 0.000332456786598914 |
GO:0015698 | inorganic anion transport | 0.000429192999854446 |
GO:0006820 | anion transport | 0.000671512432102679 |
GO:0051216 | cartilage development | 0.00182731708572627 |
GO:0030246 | carbohydrate binding | 0.00238614933504166 |
GO:0005615 | extracellular space | 0.00306266264442543 |
GO:0005539 | glycosaminoglycan binding | 0.00374314072995 |
GO:0030247 | polysaccharide binding | 0.0042839181942941 |
GO:0001871 | pattern binding | 0.00451696322521827 |
GO:0001501 | skeletal development | 0.0189008761426242 |
GO:0005529 | sugar binding | 0.0193667460790394 |
GO:0016337 | cell-cell adhesion | 0.0231487892777975 |
GO:0006811 | ion transport | 0.0260616293747252 |
GO:0030166 | proteoglycan biosynthetic process | 0.0285255231838653 |
GO:0044262 | cellular carbohydrate metabolic process | 0.0292110437925668 |
GO:0009888 | tissue development | 0.0345915528954376 |
GO:0005921 | gap junction | 0.039418383839295 |
GO:0005975 | carbohydrate metabolic process | 0.0473343727651521 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
appendage | 1.45e-15 | 12 |
paired limb/fin | 1.45e-15 | 12 |
limb | 1.45e-15 | 12 |
paired limb/fin bud | 1.45e-15 | 12 |
limb bud | 1.45e-15 | 12 |
limb/fin field | 1.45e-15 | 12 |
limb field | 1.45e-15 | 12 |
appendage girdle complex | 4.52e-14 | 13 |
surface structure | 4.80e-12 | 22 |
forelimb | 1.43e-09 | 7 |
pectoral appendage | 1.43e-09 | 7 |
pectoral appendage bud | 1.43e-09 | 7 |
forelimb bud | 1.43e-09 | 7 |
forelimb/pectoral fin field | 1.43e-09 | 7 |
pectoral complex | 3.63e-08 | 8 |
subdivision of skeletal system | 5.86e-08 | 6 |
developing mesenchymal condensation | 5.86e-08 | 6 |
pre-cartilage condensation | 5.86e-08 | 6 |
cartilaginous condensation | 5.86e-08 | 6 |
hindlimb bud | 1.64e-07 | 5 |
stylopod | 1.64e-07 | 5 |
lower limb segment | 1.64e-07 | 5 |
multi-limb segment region | 1.64e-07 | 5 |
pelvic appendage | 1.64e-07 | 5 |
limb segment | 1.64e-07 | 5 |
paired limb/fin segment | 1.64e-07 | 5 |
pelvic appendage bud | 1.64e-07 | 5 |
subdivision of organism along appendicular axis | 1.64e-07 | 5 |
leg | 1.64e-07 | 5 |
hindlimb | 1.64e-07 | 5 |
hindlimb stylopod | 1.64e-07 | 5 |
posterior region of body | 1.64e-07 | 5 |
pelvic complex | 1.64e-07 | 5 |
hindlimb/pelvic fin field | 1.64e-07 | 5 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.208917 |
MA0004.1 | 0.0523019 |
MA0006.1 | 0.307617 |
MA0007.1 | 0.178699 |
MA0009.1 | 0.30322 |
MA0014.1 | 0.376865 |
MA0017.1 | 0.368292 |
MA0019.1 | 0.177916 |
MA0024.1 | 0.745934 |
MA0025.1 | 0.490939 |
MA0027.1 | 1.84332 |
MA0028.1 | 0.0625976 |
MA0029.1 | 0.255531 |
MA0030.1 | 0.260188 |
MA0031.1 | 0.235297 |
MA0038.1 | 0.114851 |
MA0040.1 | 0.312625 |
MA0041.1 | 0.122365 |
MA0042.1 | 0.111518 |
MA0043.1 | 0.37807 |
MA0046.1 | 0.330453 |
MA0048.1 | 1.13075 |
MA0050.1 | 0.0666657 |
MA0051.1 | 0.119487 |
MA0052.1 | 0.318728 |
MA0055.1 | 0.60771 |
MA0056.1 | 0 |
MA0057.1 | 0.285369 |
MA0058.1 | 0.0249251 |
MA0059.1 | 0.0277969 |
MA0060.1 | 0.0678139 |
MA0061.1 | 0.840046 |
MA0063.1 | 0 |
MA0066.1 | 0.71687 |
MA0067.1 | 0.587517 |
MA0068.1 | 0.0237618 |
MA0069.1 | 0.318986 |
MA0070.1 | 0.311646 |
MA0071.1 | 0.507269 |
MA0072.1 | 0.823673 |
MA0073.1 | 1.23114 |
MA0074.1 | 0.307062 |
MA0076.1 | 0.0191324 |
MA0077.1 | 0.289168 |
MA0078.1 | 0.13731 |
MA0081.1 | 0.135744 |
MA0083.1 | 0.377437 |
MA0084.1 | 0.888928 |
MA0087.1 | 0.343502 |
MA0088.1 | 0.329408 |
MA0089.1 | 0 |
MA0090.1 | 1.01672 |
MA0091.1 | 1.20933 |
MA0092.1 | 0.366076 |
MA0093.1 | 0.0143916 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.292642 |
MA0101.1 | 0.859809 |
MA0103.1 | 0.394121 |
MA0105.1 | 0.966856 |
MA0106.1 | 2.00021 |
MA0107.1 | 1.29817 |
MA0108.2 | 0.56139 |
MA0109.1 | 0 |
MA0111.1 | 0.391982 |
MA0113.1 | 0.126154 |
MA0114.1 | 1.13193 |
MA0115.1 | 0.380305 |
MA0116.1 | 0.307163 |
MA0117.1 | 0.354763 |
MA0119.1 | 0.295109 |
MA0122.1 | 0.370415 |
MA0124.1 | 1.33622 |
MA0125.1 | 1.20061 |
MA0130.1 | 0 |
MA0131.1 | 0.519826 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.04987 |
MA0136.1 | 0.10138 |
MA0139.1 | 0.20766 |
MA0140.1 | 0.0866252 |
MA0141.1 | 0.719674 |
MA0142.1 | 0.225403 |
MA0143.1 | 0.135052 |
MA0144.1 | 0.206664 |
MA0145.1 | 0.379282 |
MA0146.1 | 0.0245201 |
MA0147.1 | 0.230012 |
MA0148.1 | 1.22213 |
MA0149.1 | 0.0314134 |
MA0062.2 | 0.000890599 |
MA0035.2 | 0.0887515 |
MA0039.2 | 0.458645 |
MA0138.2 | 0.170255 |
MA0002.2 | 0.548365 |
MA0137.2 | 0.228652 |
MA0104.2 | 0.131384 |
MA0047.2 | 1.21458 |
MA0112.2 | 1.64242 |
MA0065.2 | 1.94543 |
MA0150.1 | 0.0472137 |
MA0151.1 | 0 |
MA0152.1 | 0.114512 |
MA0153.1 | 0.42102 |
MA0154.1 | 0.654845 |
MA0155.1 | 0.834128 |
MA0156.1 | 0.0189666 |
MA0157.1 | 0.204086 |
MA0158.1 | 0 |
MA0159.1 | 0.11994 |
MA0160.1 | 0.214615 |
MA0161.1 | 0 |
MA0162.1 | 0.0685264 |
MA0163.1 | 0.893125 |
MA0164.1 | 0.332928 |
MA0080.2 | 0.0166373 |
MA0018.2 | 0.10631 |
MA0099.2 | 0.166437 |
MA0079.2 | 0.0104093 |
MA0102.2 | 0.938682 |
MA0258.1 | 0.321845 |
MA0259.1 | 0.0976349 |
MA0442.1 | 0 |