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MCL coexpression mm9:497: Difference between revisions

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{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0004245;neprilysin activity;0.032765781590713;18675!GO:0004467;long-chain-fatty-acid-CoA ligase activity;0.032765781590713;225579!GO:0015645;fatty-acid ligase activity;0.032765781590713;225579!GO:0001676;long-chain fatty acid metabolic process;0.032765781590713;225579!GO:0016877;ligase activity, forming carbon-sulfur bonds;0.0430423622096199;225579!
}}

Latest revision as of 15:24, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr14:119536766..119536773,+p@chr14:119536766..119536773
+
Mm9::chr18:58715612..58715663,+p1@Slc27a6
Mm9::chr18:58715665..58715701,+p3@Slc27a6
Mm9::chr18:58715716..58715727,+p4@Slc27a6
Mm9::chr18:58715730..58715735,+p7@Slc27a6
Mm9::chr18:58715744..58715754,+p6@Slc27a6
Mm9::chr18:58715854..58715870,+p5@Slc27a6
Mm9::chr18:58715878..58715900,+p2@Slc27a6
Mm9::chr18:58772481..58772486,+p@chr18:58772481..58772486
+
Mm9::chr1:135152659..135152676,+p@chr1:135152659..135152676
+
Mm9::chr1:135152690..135152732,+p@chr1:135152690..135152732
+
Mm9::chr1:51037934..51037949,-p@chr1:51037934..51037949
-
Mm9::chr2:172219448..172219464,+p1@Cass4
Mm9::chr8:105310531..105310551,-p@chr8:105310531..105310551
-
Mm9::chrX:153853025..153853036,-p4@Phex


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004245neprilysin activity0.032765781590713
GO:0004467long-chain-fatty-acid-CoA ligase activity0.032765781590713
GO:0015645fatty-acid ligase activity0.032765781590713
GO:0001676long-chain fatty acid metabolic process0.032765781590713
GO:0016877ligase activity, forming carbon-sulfur bonds0.0430423622096199



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
lung1.79e-1614
respiratory tube1.79e-1614
respiration organ1.79e-1614
pair of lungs1.79e-1614
lung primordium1.79e-1614
lung bud1.79e-1614
epithelial bud1.16e-1217
thoracic cavity element1.16e-1217
thoracic segment organ1.16e-1217
thoracic cavity1.16e-1217
thoracic segment of trunk1.16e-1217
respiratory primordium1.16e-1217
endoderm of foregut1.16e-1217
epithelial fold5.02e-1020
breast1.99e-076
chest1.99e-076
anatomical space8.43e-0757


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.13442
MA0004.10.239244
MA0006.10.118059
MA0007.10.227553
MA0009.10.623671
MA0014.10.304428
MA0017.10.420732
MA0019.11.15568
MA0024.10.582844
MA0025.10.845702
MA0027.12.24512
MA0028.10.12472
MA0029.10.562703
MA0030.10.568779
MA0031.10.535959
MA0038.10.358622
MA0040.10.635404
MA0041.10.18185
MA0042.10.172351
MA0043.10.71494
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