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{{UBERON
{{UBERON
|id=UBERON:0002371
|alt_id=UBERON:FMA_9608-MA_0000134-MIAA_0000084-XAO_0000123-ZFA_0000669
|name=bone marrow
|namespace=
|def="flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells[WP]." [Wikipedia:Bone_marrow]
|xref=AAO:0011007;;BTO:0000141;;BTO:0000829;;EFO:0000868;;EV:0100046;;FMA:9608;;GAID:1287;;galen:BoneMarrow;;http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg;;MA:0000134;;MAT:0000084;;MESH:A.15.382.216;;MIAA:0000084;;ncithesaurus:Bone_Marrow;;OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA;;SCTID:421320006;;VHOG:0001218;;XAO:0000123
|is_a=UBERON:0000479;;UBERON:0004120
|synonym="anterior kidney" RELATED [];;"head kidney" BROAD [];;"kidney marrow" RELATED [];;"medulla of bone" RELATED [BTO:0000141];;"medulla ossea" EXACT [];;"medulla ossium" RELATED LATIN [Wikipedia:Bone_marrow];;"medulla ossium" RELATED [BTO:0000141]
|comment=TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs
|comment=TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs
|alt_id=UBERON:FMA_9608-MA_0000134-MIAA_0000084-XAO_0000123-ZFA_0000669
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells[WP]." [Wikipedia:Bone_marrow]
|subset=uberon_slim
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0002371
|is_a=UBERON:0012429
|is_obsolete=
|located_in=
|located_in=
|name=bone marrow
|namespace=
|obo_creation_date=
|part_of=UBERON:0001474;;UBERON:0002390;;UBERON:0002405
|part_of=UBERON:0001474;;UBERON:0002390;;UBERON:0002405
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|is_obsolete=
|subset=uberon_slim
|preceded_by=
|synonym="anterior kidney" RELATED [];;"head kidney" BROAD [];;"kidney marrow" RELATED [];;"medulla of bone" RELATED [BTO:0000141];;"medulla ossea" EXACT [];;"medulla ossium" RELATED LATIN [Wikipedia:Bone_marrow];;"medulla ossium" RELATED [BTO:0000141]
|union_of=
|xref=AAO:0011007;;BTO:0000141;;BTO:0000829;;EFO:0000868;;EV:0100046;;FMA:9608;;GAID:1287;;galen:BoneMarrow;;http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg;;MA:0000134;;MAT:0000084;;MESH:A.15.382.216;;MIAA:0000084;;ncithesaurus:Bone_Marrow;;OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA;;SCTID:421320006;;VHOG:0001218;;XAO:0000123
}}
}}

Revision as of 11:15, 12 September 2014

Name:bone marrow
Definition:"flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells[WP]." [Wikipedia:Bone_marrow]
Xrefs:
links:

AAO:0011007
BTO:0000141
BTO:0000829
EFO:0000868
EV:0100046
FMA:9608
GAID:1287
galen:BoneMarrow
[1]
MA:0000134
MAT:0000084
MESH:A.15.382.216
MIAA:0000084
ncithesaurus:Bone_Marrow
OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA
SCTID:421320006
VHOG:0001218

XAO:0000123
Synonyms: "anterior kidney" RELATED []
"head kidney" BROAD []
"kidney marrow" RELATED []
"medulla of bone" RELATED [BTO:0000141]
"medulla ossea" EXACT []
"medulla ossium" RELATED LATIN [Wikipedia:Bone_marrow]
"medulla ossium" RELATED [BTO:0000141]
Comments:TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs
Alt_id: UBERON:FMA_9608-MA_0000134-MIAA_0000084-XAO_0000123-ZFA_0000669
Subset: uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0012429(hemopoietic tissue)
part_of:UBERON:0001474(bone element),UBERON:0002390(hematopoietic system),UBERON:0002405(immune system)



Children

derives from:FF:0010192 (human bone marrow - adult sample),FF:0200020 (osteoclast, bone marrow-derived sample),FF:0200029 (hematopoietic stem cell, bone marrow derived sample)
part of:CL:0000556 (megakaryocyte),CL:0000557 (granulocyte monocyte progenitor cell),CL:0002092 (bone marrow cell),CL:0002476 (bone marrow macrophage),CL:0002540 (mesenchymal stem cell of the bone marrow),UBERON:0007195 (stroma of bone marrow),CL:1001610 (bone marrow hematopoietic cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002371 (bone marrow), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
3.02e-119FFCP PHASE1:Hg19::chr1:161187824..161187847,+#_fb288fb0dd4490ba420de939d7b549c6p@chr1:161187824..161187847, +
3.02e-119FFCP PHASE2:Hg19::chr1:161187824..161187847,+#_fb288fb0dd4490ba420de939d7b549c6p@chr1:161187824..161187847, +
7.29e-115FFCP PHASE1:Hg19::chr16:50313426..50313459,+#_0f7bf86989a2da0c0782b39d099bd003p@chr16:50313426..50313459, +
7.29e-115FFCP PHASE2:Hg19::chr16:50313426..50313459,+#_0f7bf86989a2da0c0782b39d099bd003p@chr16:50313426..50313459, +
1.19e-114FFCP PHASE2:Hg19::chr1:161188661..161188679,+#_f05fbde14200f076ddb4fbaa2a643511p@chr1:161188661..161188679, +
1.19e-114FFCP PHASE1:Hg19::chr1:161188661..161188679,+#_f05fbde14200f076ddb4fbaa2a643511p@chr1:161188661..161188679, +
4.24e-113FFCP PHASE1:Hg19::chr18:2847062..2847071,+#_b3c9078f5b6cbfc07d37145982131b60p7@EMILIN2
4.24e-113FFCP PHASE2:Hg19::chr18:2847062..2847071,+#_b3c9078f5b6cbfc07d37145982131b60p7@EMILIN2
1.01e-112FFCP PHASE1:Hg19::chr7:77050554..77050601,+#_2e0774b534916bd0083c05f67a9b4bdcp@chr7:77050554..77050601, +
1.01e-112FFCP PHASE2:Hg19::chr7:77050554..77050601,+#_2e0774b534916bd0083c05f67a9b4bdcp@chr7:77050554..77050601, +
1.9e-111FFCP PHASE1:Hg19::chr1:161188746..161188758,+#_c358df2711241791bf4fc993444f90c0p@chr1:161188746..161188758, +
1.9e-111FFCP PHASE2:Hg19::chr1:161188746..161188758,+#_c358df2711241791bf4fc993444f90c0p@chr1:161188746..161188758, +
7.78e-111FFCP PHASE2:Hg19::chr17:7482481..7482508,-#_fea5d07b0a7ac31f193be8b2dd36553dp@chr17:7482481..7482508, -
7.78e-111FFCP PHASE1:Hg19::chr17:7482481..7482508,-#_fea5d07b0a7ac31f193be8b2dd36553dp@chr17:7482481..7482508, -
2.59e-110FFCP PHASE1:Hg19::chr19:18288651..18288682,+#_8420d68ef0d380fba0fee47cc4bf47c6p5@IFI30
2.59e-110FFCP PHASE2:Hg19::chr19:18288651..18288682,+#_8420d68ef0d380fba0fee47cc4bf47c6p5@IFI30
5.16e-109FFCP PHASE2:Hg19::chr4:3387239..3387324,-#_72086cba4aa5b69ab20eee096ff962c4p@chr4:3387239..3387324, -
5.16e-109FFCP PHASE1:Hg19::chr4:3387239..3387324,-#_72086cba4aa5b69ab20eee096ff962c4p@chr4:3387239..3387324, -
1.18e-107FFCP PHASE1:Hg19::chr7:2832730..2832791,+#_536c1801722acc7850108a0aefb2bac6p@chr7:2832730..2832791, +
1.18e-107FFCP PHASE2:Hg19::chr7:2832730..2832791,+#_536c1801722acc7850108a0aefb2bac6p@chr7:2832730..2832791, +
7.69e-107FFCP PHASE2:Hg19::chr5:180242646..180242657,-#_00a7aef9980fdd13dbb72f4993ca7431p15@MGAT1
7.69e-107FFCP PHASE1:Hg19::chr5:180242646..180242657,-#_00a7aef9980fdd13dbb72f4993ca7431p15@MGAT1
2.19e-106FFCP PHASE1:Hg19::chr19:18288828..18288861,+#_86423e31ee228d41f7578b87f9cbd65fp7@IFI30
2.19e-106FFCP PHASE2:Hg19::chr19:18288828..18288861,+#_86423e31ee228d41f7578b87f9cbd65fp7@IFI30
4.2e-106FFCP PHASE2:Hg19::chr1:111743000..111743011,+#_edaee5933a9448bc812c28369aaa999dp8@CHI3L2
4.2e-106FFCP PHASE1:Hg19::chr1:111743000..111743011,+#_edaee5933a9448bc812c28369aaa999dp8@CHI3L2
9.25e-106FFCP PHASE2:Hg19::chr17:40168698..40168726,-#_9d42f22ed206a684bd783c92e03ceafcp1@AK126179
9.25e-106FFCP PHASE1:Hg19::chr17:40168698..40168726,-#_9d42f22ed206a684bd783c92e03ceafcp1@AK126179
6.0e-105FFCP PHASE2:Hg19::chr2:145429606..145429658,+#_fe5c7ce6cec85a35db1f1742408f3fbep@chr2:145429606..145429658, +
6.0e-105FFCP PHASE1:Hg19::chr2:145429606..145429658,+#_fe5c7ce6cec85a35db1f1742408f3fbep@chr2:145429606..145429658, +
1.54e-104FFCP PHASE1:Hg19::chr19:18286116..18286156,+#_37ab9a6aa1d27a2728af9a15e0a16317p@chr19:18286116..18286156, +
1.54e-104FFCP PHASE2:Hg19::chr19:18286116..18286156,+#_37ab9a6aa1d27a2728af9a15e0a16317p@chr19:18286116..18286156, +
3.16e-104FFCP PHASE1:Hg19::chr17:72542163..72542182,-#_3a3a7b8f3ab968ecc956e6614f9a10c6p2@CD300C
3.16e-104FFCP PHASE2:Hg19::chr17:72542163..72542182,-#_3a3a7b8f3ab968ecc956e6614f9a10c6p2@CD300C
2.33e-103FFCP PHASE1:Hg19::chr2:38358217..38358244,+#_525ade17346c48bec4dee470edcf267cp1@CYP1B1-AS1
2.33e-103FFCP PHASE2:Hg19::chr2:38358217..38358244,+#_525ade17346c48bec4dee470edcf267cp1@CYP1B1-AS1
3.32e-103FFCP PHASE1:Hg19::chr15:65174546..65174583,-#_275d4c4bbe0182dfc53910d2a26aa518p@chr15:65174546..65174583, -
3.32e-103FFCP PHASE2:Hg19::chr15:65174546..65174583,-#_275d4c4bbe0182dfc53910d2a26aa518p@chr15:65174546..65174583, -
6.1e-103FFCP PHASE1:Hg19::chr4:159727272..159727307,+#_13028d7e697d6a5ca6fa36e0abc17c4cp7@FNIP2
6.1e-103FFCP PHASE2:Hg19::chr4:159727272..159727307,+#_13028d7e697d6a5ca6fa36e0abc17c4cp7@FNIP2
1.77e-102FFCP PHASE2:Hg19::chr4:185314125..185314143,-#_356752c12b6ba55692e1e2ac59a532d1p@chr4:185314125..185314143, -
1.77e-102FFCP PHASE1:Hg19::chr4:185314125..185314143,-#_356752c12b6ba55692e1e2ac59a532d1p@chr4:185314125..185314143, -
3.48e-102FFCP PHASE2:Hg19::chr3:149531627..149531651,+#_4c67fa311721a70714ee3ed1474222ebp7@RNF13
3.48e-102FFCP PHASE1:Hg19::chr3:149531627..149531651,+#_4c67fa311721a70714ee3ed1474222ebp7@RNF13
9.05e-102FFCP PHASE1:Hg19::chr19:52299474..52299504,-#_9a853885e7d51cfad8df78758a993a25p@chr19:52299474..52299504, -
9.05e-102FFCP PHASE2:Hg19::chr19:52299474..52299504,-#_9a853885e7d51cfad8df78758a993a25p@chr19:52299474..52299504, -
1.3e-101FFCP PHASE2:Hg19::chr1:161188686..161188721,+#_5356f7331a9a7f1e4acca94148ff9da0p@chr1:161188686..161188721, +
1.3e-101FFCP PHASE1:Hg19::chr1:161188686..161188721,+#_5356f7331a9a7f1e4acca94148ff9da0p@chr1:161188686..161188721, +
2.05e-101FFCP PHASE1:Hg19::chr5:131280548..131280574,-#_544475e36132fd7889ad7b5283b019bdp1@ENST00000425320
2.05e-101FFCP PHASE2:Hg19::chr5:131280548..131280574,-#_544475e36132fd7889ad7b5283b019bdp1@ENST00000425320
2.11e-101FFCP PHASE1:Hg19::chr2:119726719..119726744,+#_dbc8fd4ac3ddc66319ec55f1b8ec9f13p@chr2:119726719..119726744, +
2.11e-101FFCP PHASE2:Hg19::chr2:119726719..119726744,+#_dbc8fd4ac3ddc66319ec55f1b8ec9f13p@chr2:119726719..119726744, +
6.02e-101FFCP PHASE1:Hg19::chr10:73648356..73648408,-#_5ec94b6bb82431e45a3d80174933669ep@chr10:73648356..73648408, -
6.02e-101FFCP PHASE2:Hg19::chr10:73648356..73648408,-#_5ec94b6bb82431e45a3d80174933669ep@chr10:73648356..73648408, -
7.24e-101FFCP PHASE2:Hg19::chr4:185314151..185314178,-#_e3fa43a7157d560a401f9d82edfb1695p@chr4:185314151..185314178, -
7.24e-101FFCP PHASE1:Hg19::chr4:185314151..185314178,-#_e3fa43a7157d560a401f9d82edfb1695p@chr4:185314151..185314178, -
8.21e-101FFCP PHASE1:Hg19::chr19:18288064..18288080,+#_cf4fad3c0f83846e35209968edef3b93p@chr19:18288064..18288080, +
8.21e-101FFCP PHASE2:Hg19::chr19:18288064..18288080,+#_cf4fad3c0f83846e35209968edef3b93p@chr19:18288064..18288080, +
3.82e-100FFCP PHASE2:Hg19::chrX:153286067..153286101,-#_03a1bfd7d43b897cb5fbbbbd9661ffdcp@chrX:153286067..153286101, -
3.82e-100FFCP PHASE1:Hg19::chrX:153286067..153286101,-#_03a1bfd7d43b897cb5fbbbbd9661ffdcp@chrX:153286067..153286101, -
4.64e-100FFCP PHASE2:Hg19::chr4:185314188..185314207,-#_c6bd6d4e94f4e2f7729de93bcc41c515p@chr4:185314188..185314207, -
4.64e-100FFCP PHASE1:Hg19::chr4:185314188..185314207,-#_c6bd6d4e94f4e2f7729de93bcc41c515p@chr4:185314188..185314207, -
7.34e-100FFCP PHASE1:Hg19::chrX:37664331..37664352,+#_57f4cdc1a6cd84f45f77e50503072795p@chrX:37664331..37664352, +
7.34e-100FFCP PHASE2:Hg19::chrX:37664331..37664352,+#_57f4cdc1a6cd84f45f77e50503072795p@chrX:37664331..37664352, +
1.26e-99FFCP PHASE1:Hg19::chr1:150724282..150724308,-#_055516f08a1e8e4aa32e040230133b0dp8@CTSS
1.26e-99FFCP PHASE2:Hg19::chr1:150724282..150724308,-#_055516f08a1e8e4aa32e040230133b0dp8@CTSS
1.49e-99FFCP PHASE2:Hg19::chr2:145276939..145276960,+#_a5a92d3282e357a6cf89b988635d70bap2@ZEB2-AS1
1.49e-99FFCP PHASE2:Hg19::chr1:161188826..161188842,+#_a5a92d3282e357a6cf89b988635d70bap@chr1:161188826..161188842, +
1.49e-99FFCP PHASE1:Hg19::chr1:161188826..161188842,+#_a5a92d3282e357a6cf89b988635d70bap@chr1:161188826..161188842, +
1.49e-99FFCP PHASE1:Hg19::chr2:145276939..145276960,+#_a5a92d3282e357a6cf89b988635d70bap2@ZEB2-AS1
2.41e-99FFCP PHASE1:Hg19::chr8:116588888..116588904,+#_2c5ba577e02efe5816e70bac70a99fbap@chr8:116588888..116588904, +
2.41e-99FFCP PHASE2:Hg19::chr8:116588888..116588904,+#_2c5ba577e02efe5816e70bac70a99fbap@chr8:116588888..116588904, +
3.12e-99FFCP PHASE2:Hg19::chr1:145610717..145610730,+#_0ab46bde54cfc4ce5c8bf28d85cd4756p4@RNF115
3.12e-99FFCP PHASE1:Hg19::chr1:145610717..145610730,+#_0ab46bde54cfc4ce5c8bf28d85cd4756p4@RNF115
6.31e-99FFCP PHASE1:Hg19::chr19:18285955..18285972,+#_140e54e20c44befb3ff954848a52272bp@chr19:18285955..18285972, +
6.31e-99FFCP PHASE2:Hg19::chr19:18285955..18285972,+#_140e54e20c44befb3ff954848a52272bp@chr19:18285955..18285972, +
6.91e-99FFCP PHASE1:Hg19::chr2:129283966..129283970,+#_d97a175e30bb7bf19a262cc3252ee96cp@chr2:129283966..129283970, +
6.91e-99FFCP PHASE2:Hg19::chr2:129283966..129283970,+#_d97a175e30bb7bf19a262cc3252ee96cp@chr2:129283966..129283970, +
1.67e-98FFCP PHASE2:Hg19::chr1:26602990..26603008,+#_5a97f2199be8cbab7d998771cec7d267p@chr1:26602990..26603008, +
1.67e-98FFCP PHASE1:Hg19::chr1:26602990..26603008,+#_5a97f2199be8cbab7d998771cec7d267p@chr1:26602990..26603008, +
1.95e-98FFCP PHASE1:Hg19::chr1:108593061..108593077,+#_7efb429297c773ee1bacd6bd91a50feap@chr1:108593061..108593077, +
1.95e-98FFCP PHASE2:Hg19::chr1:108593061..108593077,+#_7efb429297c773ee1bacd6bd91a50feap@chr1:108593061..108593077, +
2.14e-98FFCP PHASE1:Hg19::chr19:18288914..18288931,-#_68820a8b835e7042b19099f3ade35078p5@CU676849, p5@CU689079
2.14e-98FFCP PHASE2:Hg19::chr19:18288914..18288931,-#_68820a8b835e7042b19099f3ade35078p5@CU676849, p5@CU689079
2.9e-98FFCP PHASE2:Hg19::chr20:1517991..1518011,-#_6e836f25f30cbd565f1b8d1c01d2fb1ep@chr20:1517991..1518011, -
2.9e-98FFCP PHASE1:Hg19::chr20:1517991..1518011,-#_6e836f25f30cbd565f1b8d1c01d2fb1ep@chr20:1517991..1518011, -
5.04e-98FFCP PHASE2:Hg19::chr19:18283959..18283993,+#_ee27b2938749d19386fd16683bc24e4bp@chr19:18283959..18283993, +
5.04e-98FFCP PHASE1:Hg19::chr19:18283959..18283993,+#_ee27b2938749d19386fd16683bc24e4bp@chr19:18283959..18283993, +
1.42e-97FFCP PHASE2:Hg19::chr19:18288514..18288554,+#_78e2402cbac4cff40b9afff0ae776073p6@IFI30
1.42e-97FFCP PHASE1:Hg19::chr19:18288514..18288554,+#_78e2402cbac4cff40b9afff0ae776073p6@IFI30
1.8e-97FFCP PHASE1:Hg19::chr5:180242576..180242585,-#_3a6ebe3e9d7da1bd59c8c0e104545391p12@MGAT1
1.8e-97FFCP PHASE2:Hg19::chr5:180242576..180242585,-#_3a6ebe3e9d7da1bd59c8c0e104545391p12@MGAT1
3.13e-97FFCP PHASE1:Hg19::chr8:53373491..53373506,-#_21c3a637a76eb46823f602b6f207d3a6p4@ST18
3.13e-97FFCP PHASE2:Hg19::chr8:53373491..53373506,-#_21c3a637a76eb46823f602b6f207d3a6p4@ST18
4.98e-97FFCP PHASE1:Hg19::chr7:6066589..6066602,-#_07a3dde7adcb3a69e4b98aa8a6cc758cp4@EIF2AK1
4.98e-97FFCP PHASE2:Hg19::chr7:6066589..6066602,-#_07a3dde7adcb3a69e4b98aa8a6cc758cp4@EIF2AK1
6.22e-97FFCP PHASE2:Hg19::chr17:7483714..7483726,+#_6449b142b2152f554c25e3f79a6c5491p@chr17:7483714..7483726, +
6.22e-97FFCP PHASE1:Hg19::chr17:7483714..7483726,+#_6449b142b2152f554c25e3f79a6c5491p@chr17:7483714..7483726, +
7.99e-97FFCP PHASE1:Hg19::chr7:128503395..128503414,+#_66a8556a0aed7d6b48946b1d4df7ad5fp@chr7:128503395..128503414, +
7.99e-97FFCP PHASE2:Hg19::chr7:128503395..128503414,+#_66a8556a0aed7d6b48946b1d4df7ad5fp@chr7:128503395..128503414, +

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