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{{UBERON
{{UBERON
|id=UBERON:0002405
|alt_id=UBERON:FMA_9825-MA_0002711-XAO_0003152-ZFA_0001159
|name=immune system
|namespace=
|def="Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [NLM:immune+system, Wikipedia:Immune_system]
|xref=AAO:0011003;;BILA:0000104;;FMA:9825;;GAID:328;;MA:0002711;;MESH:A.15.382;;ncithesaurus:Immune_System;;OpenCyc:Mx4rvWNkm5wpEbGdrcN5Y29ycA;;SCTID:362590003;;TAO:0001159;;VHOG:0001247;;XAO:0003152;;ZFA:0001159
|is_a=UBERON:0000467
|synonym=
|comment=This class was created automatically from a combination of ontologies
|comment=This class was created automatically from a combination of ontologies
|alt_id=UBERON:FMA_9825-MA_0002711-XAO_0003152-ZFA_0001159
|disjoint_from=UBERON:0002416;;UBERON:0002423;;UBERON:0004456
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [NLM:immune+system, Wikipedia:Immune_system]
|subset=uberon_slim;;vertebrate_core
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=UBERON:0002416;;UBERON:0002423;;UBERON:0004456
|has_quality=
|has_quality=
|id=UBERON:0002405
|is_a=UBERON:0000467
|is_obsolete=
|located_in=
|located_in=
|name=immune system
|namespace=FANTOM
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|is_obsolete=
|subset=uberon_slim;;vertebrate_core
|preceded_by=
|synonym=
|union_of=
|xref=AAO:0011003;;BILA:0000104;;FMA:9825;;GAID:328;;MA:0002711;;MESH:A.15.382;;ncithesaurus:Immune_System;;OpenCyc:Mx4rvWNkm5wpEbGdrcN5Y29ycA;;SCTID:362590003;;TAO:0001159;;VHOG:0001247;;XAO:0003152;;ZFA:0001159
}}
}}

Latest revision as of 17:31, 12 September 2014

Name:immune system
Namespace:FANTOM
Definition:"Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [NLM:immune+system, Wikipedia:Immune_system]
Xrefs:
links:

AAO:0011003
BILA:0000104
FMA:9825
GAID:328
MA:0002711
MESH:A.15.382
ncithesaurus:Immune_System
OpenCyc:Mx4rvWNkm5wpEbGdrcN5Y29ycA
SCTID:362590003
TAO:0001159
VHOG:0001247
XAO:0003152

ZFA:0001159
Comments:This class was created automatically from a combination of ontologies
Alt_id: UBERON:FMA_9825-MA_0002711-XAO_0003152-ZFA_0001159
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0000467(anatomical system)
disjoint_from:UBERON:0002416(integumental system),UBERON:0002423(hepatobiliary system),UBERON:0004456(entire sense organ system)



Children

disjoint from:UBERON:0000949 (endocrine system),UBERON:0000990 (reproductive system),UBERON:0001004 (respiratory system),UBERON:0001007 (digestive system),UBERON:0001008 (renal system),UBERON:0001009 (circulatory system),UBERON:0001016 (nervous system),UBERON:0001033 (gustatory system),UBERON:0001434 (skeletal system),UBERON:0002204 (musculoskeletal system),UBERON:0002294 (biliary system),UBERON:0002330 (exocrine system),UBERON:0002390 (hematopoietic system)
part of:CL:0000738 (leukocyte),UBERON:0002106 (spleen),UBERON:0002370 (thymus),UBERON:0002371 (bone marrow),UBERON:0002465 (lymphoid system),UBERON:0005057 (immune organ),UBERON:0005562 (thymus primordium)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002405 (immune system), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
7.86e-103FFCP PHASE2:Hg19::chr1:161187824..161187847,+#_f04738958b767004a48281a58084edb6p@chr1:161187824..161187847, +
7.86e-103FFCP PHASE1:Hg19::chr1:161187824..161187847,+#_f04738958b767004a48281a58084edb6p@chr1:161187824..161187847, +
3.11e-98FFCP PHASE1:Hg19::chr16:50313426..50313459,+#_8b6cc8bb6b0fb209f437c48b99bbca70p@chr16:50313426..50313459, +
3.11e-98FFCP PHASE2:Hg19::chr16:50313426..50313459,+#_8b6cc8bb6b0fb209f437c48b99bbca70p@chr16:50313426..50313459, +
1.87e-96FFCP PHASE2:Hg19::chr1:161188746..161188758,+#_7836a647c165b721cc84c67cda4e8d98p@chr1:161188746..161188758, +
1.87e-96FFCP PHASE1:Hg19::chr1:161188746..161188758,+#_7836a647c165b721cc84c67cda4e8d98p@chr1:161188746..161188758, +
2.36e-95FFCP PHASE2:Hg19::chr1:161188661..161188679,+#_0ef797085235fd62fb1badf4458d0cbcp@chr1:161188661..161188679, +
2.36e-95FFCP PHASE1:Hg19::chr1:161188661..161188679,+#_0ef797085235fd62fb1badf4458d0cbcp@chr1:161188661..161188679, +
2.31e-92FFCP PHASE2:Hg19::chr4:159727272..159727307,+#_0b3ccdfa43be8c928a79abf0389931b9p7@FNIP2
2.31e-92FFCP PHASE1:Hg19::chr4:159727272..159727307,+#_0b3ccdfa43be8c928a79abf0389931b9p7@FNIP2
8.32e-92FFCP PHASE2:Hg19::chr19:18288651..18288682,+#_bc4206de4156c3d81448bc077462a555p5@IFI30
8.32e-92FFCP PHASE1:Hg19::chr19:18288651..18288682,+#_bc4206de4156c3d81448bc077462a555p5@IFI30
6.63e-91FFCP PHASE2:Hg19::chr4:185314151..185314178,-#_b4341d1965f5ed3e5ace3de425ca6fb6p@chr4:185314151..185314178, -
6.63e-91FFCP PHASE1:Hg19::chr4:185314151..185314178,-#_b4341d1965f5ed3e5ace3de425ca6fb6p@chr4:185314151..185314178, -
2.23e-90FFCP PHASE2:Hg19::chr7:77050554..77050601,+#_19c710b896653b31c64e51ef20dd0e7ep@chr7:77050554..77050601, +
2.23e-90FFCP PHASE1:Hg19::chr7:77050554..77050601,+#_19c710b896653b31c64e51ef20dd0e7ep@chr7:77050554..77050601, +
4.39e-90FFCP PHASE2:Hg19::chr18:2847062..2847071,+#_c80550db7e9536f2f8dbba0bd975c5eap7@EMILIN2
4.39e-90FFCP PHASE1:Hg19::chr18:2847062..2847071,+#_c80550db7e9536f2f8dbba0bd975c5eap7@EMILIN2
5.36e-89FFCP PHASE2:Hg19::chr17:7482481..7482508,-#_49d141d286a8eaaada8ee37e3a972ac8p@chr17:7482481..7482508, -
5.36e-89FFCP PHASE1:Hg19::chr17:7482481..7482508,-#_49d141d286a8eaaada8ee37e3a972ac8p@chr17:7482481..7482508, -
2.0e-88FFCP PHASE1:Hg19::chr4:185314125..185314143,-#_cd05e8ab035b92ca916ea4a06a614227p@chr4:185314125..185314143, -
2.0e-88FFCP PHASE2:Hg19::chr4:185314125..185314143,-#_cd05e8ab035b92ca916ea4a06a614227p@chr4:185314125..185314143, -
2.39e-88FFCP PHASE2:Hg19::chr1:111743000..111743011,+#_d3f7c7998a2647a4d58e5d077d972d57p8@CHI3L2
2.39e-88FFCP PHASE1:Hg19::chr1:111743000..111743011,+#_d3f7c7998a2647a4d58e5d077d972d57p8@CHI3L2
2.46e-88FFCP PHASE2:Hg19::chr19:18288828..18288861,+#_5a15a643cc970050936b5c7778e72e1ap7@IFI30
2.46e-88FFCP PHASE1:Hg19::chr19:18288828..18288861,+#_5a15a643cc970050936b5c7778e72e1ap7@IFI30
1.07e-87FFCP PHASE2:Hg19::chr4:185314188..185314207,-#_544c8dc3a59df3c55fbc02f17fac0812p@chr4:185314188..185314207, -
1.07e-87FFCP PHASE1:Hg19::chr4:185314188..185314207,-#_544c8dc3a59df3c55fbc02f17fac0812p@chr4:185314188..185314207, -
3.43e-87FFCP PHASE1:Hg19::chr1:161188686..161188721,+#_b3084553dc9447291fb089ea04ae9f2fp@chr1:161188686..161188721, +
3.43e-87FFCP PHASE2:Hg19::chr1:161188686..161188721,+#_b3084553dc9447291fb089ea04ae9f2fp@chr1:161188686..161188721, +
1.51e-86FFCP PHASE1:Hg19::chr4:3387239..3387324,-#_dae8c6e948f53c3feba9c00344599c74p@chr4:3387239..3387324, -
1.51e-86FFCP PHASE2:Hg19::chr4:3387239..3387324,-#_dae8c6e948f53c3feba9c00344599c74p@chr4:3387239..3387324, -
4.76e-86FFCP PHASE2:Hg19::chr7:2832730..2832791,+#_8692f22a0f543448b5aa0fcf02a87029p@chr7:2832730..2832791, +
4.76e-86FFCP PHASE1:Hg19::chr7:2832730..2832791,+#_8692f22a0f543448b5aa0fcf02a87029p@chr7:2832730..2832791, +
1.19e-85FFCP PHASE2:Hg19::chr5:180242646..180242657,-#_ab22e60957938afa71f2286c95f0112fp15@MGAT1
1.19e-85FFCP PHASE1:Hg19::chr5:180242646..180242657,-#_ab22e60957938afa71f2286c95f0112fp15@MGAT1
1.83e-85FFCP PHASE2:Hg19::chr1:161188826..161188842,+#_b5232bfda69abea263d28b323c5325b6p@chr1:161188826..161188842, +
1.83e-85FFCP PHASE1:Hg19::chr1:161188826..161188842,+#_b5232bfda69abea263d28b323c5325b6p@chr1:161188826..161188842, +
1.01e-84FFCP PHASE1:Hg19::chr17:7483714..7483726,+#_faffad48dd6298a7eee2b1b373f8348ep@chr17:7483714..7483726, +
1.01e-84FFCP PHASE2:Hg19::chr17:7483714..7483726,+#_faffad48dd6298a7eee2b1b373f8348ep@chr17:7483714..7483726, +
1.19e-84FFCP PHASE2:Hg19::chr17:40168698..40168726,-#_0e749e31020a5e629ccccefeeed78106p1@AK126179
1.19e-84FFCP PHASE1:Hg19::chr17:40168698..40168726,-#_0e749e31020a5e629ccccefeeed78106p1@AK126179
7.07e-84FFCP PHASE1:Hg19::chr2:145429606..145429658,+#_cee7eb3cb5ff959a2bd04178b117be78p@chr2:145429606..145429658, +
7.07e-84FFCP PHASE2:Hg19::chr2:145429606..145429658,+#_cee7eb3cb5ff959a2bd04178b117be78p@chr2:145429606..145429658, +
9.51e-84FFCP PHASE2:Hg19::chr2:119726719..119726744,+#_099e9bd6b654d9ea3299245488fcbb56p@chr2:119726719..119726744, +
9.51e-84FFCP PHASE1:Hg19::chr2:119726719..119726744,+#_099e9bd6b654d9ea3299245488fcbb56p@chr2:119726719..119726744, +
9.61e-84FFCP PHASE2:Hg19::chr20:1517945..1517963,-#_4516a0358dafd8885e2f9a73b9119cc1p@chr20:1517945..1517963, -
9.61e-84FFCP PHASE1:Hg19::chr20:1517945..1517963,-#_4516a0358dafd8885e2f9a73b9119cc1p@chr20:1517945..1517963, -
1.61e-83FFCP PHASE1:Hg19::chr19:18283959..18283993,+#_5adaf159dd23255a2817a54410d48467p@chr19:18283959..18283993, +
1.61e-83FFCP PHASE2:Hg19::chr19:18283959..18283993,+#_5adaf159dd23255a2817a54410d48467p@chr19:18283959..18283993, +
3.47e-83FFCP PHASE2:Hg19::chr1:155959853..155959881,-#_d1b9661981898852df6a6d6eca8d6378p11@ARHGEF2
3.47e-83FFCP PHASE1:Hg19::chr1:155959853..155959881,-#_d1b9661981898852df6a6d6eca8d6378p11@ARHGEF2
3.54e-83FFCP PHASE1:Hg19::chr17:72542163..72542182,-#_b5d8b68fd02058b8fc421b80a92a08b1p2@CD300C
3.54e-83FFCP PHASE2:Hg19::chr17:72542163..72542182,-#_b5d8b68fd02058b8fc421b80a92a08b1p2@CD300C
3.78e-83FFCP PHASE1:Hg19::chr19:18286116..18286156,+#_ad00d4dadaadd6554b30287eb771a80cp@chr19:18286116..18286156, +
3.78e-83FFCP PHASE2:Hg19::chr19:18286116..18286156,+#_ad00d4dadaadd6554b30287eb771a80cp@chr19:18286116..18286156, +
1.52e-82FFCP PHASE2:Hg19::chr2:38358217..38358244,+#_4d5cc917ce0caa6716dac1b1ed96debcp1@CYP1B1-AS1
1.52e-82FFCP PHASE1:Hg19::chr2:38358217..38358244,+#_4d5cc917ce0caa6716dac1b1ed96debcp1@CYP1B1-AS1
3.08e-82FFCP PHASE1:Hg19::chr15:65174546..65174583,-#_3cfd9460878e6180522de19b1ec6fc7ap@chr15:65174546..65174583, -
3.08e-82FFCP PHASE2:Hg19::chr15:65174546..65174583,-#_3cfd9460878e6180522de19b1ec6fc7ap@chr15:65174546..65174583, -
9.01e-82FFCP PHASE2:Hg19::chr3:149531627..149531651,+#_afe025c09a8e1ce988da798a0ee3def2p7@RNF13
9.01e-82FFCP PHASE1:Hg19::chr3:149531627..149531651,+#_afe025c09a8e1ce988da798a0ee3def2p7@RNF13
1.25e-81FFCP PHASE2:Hg19::chr1:161187774..161187799,+#_8ba9e833a152f8f627eff2997a4dea8cp@chr1:161187774..161187799, +
1.25e-81FFCP PHASE1:Hg19::chr1:161187774..161187799,+#_8ba9e833a152f8f627eff2997a4dea8cp@chr1:161187774..161187799, +
1.36e-81FFCP PHASE2:Hg19::chr9:137264970..137264982,+#_0e894dc13f37ab6a6bf1b1ef84071358p@chr9:137264970..137264982, +
1.36e-81FFCP PHASE1:Hg19::chr9:137264970..137264982,+#_0e894dc13f37ab6a6bf1b1ef84071358p@chr9:137264970..137264982, +
1.38e-81FFCP PHASE1:Hg19::chr19:52299474..52299504,-#_8c8214494abd0d28be834978a94f4a8cp@chr19:52299474..52299504, -
1.38e-81FFCP PHASE2:Hg19::chr19:52299474..52299504,-#_8c8214494abd0d28be834978a94f4a8cp@chr19:52299474..52299504, -
1.88e-81FFCP PHASE2:Hg19::chr5:131280548..131280574,-#_7e5166eb8c5073e8d5bf0fd2d53ff339p1@ENST00000425320
1.88e-81FFCP PHASE1:Hg19::chr5:131280548..131280574,-#_7e5166eb8c5073e8d5bf0fd2d53ff339p1@ENST00000425320
4.02e-81FFCP PHASE2:Hg19::chr19:18288064..18288080,+#_850a313d089f85e817a10105a23bb981p@chr19:18288064..18288080, +
4.02e-81FFCP PHASE1:Hg19::chr19:18288064..18288080,+#_850a313d089f85e817a10105a23bb981p@chr19:18288064..18288080, +
1.01e-80FFCP PHASE2:Hg19::chr10:73648356..73648408,-#_593cd7f34197bfcbfd65d679d1b79539p@chr10:73648356..73648408, -
1.01e-80FFCP PHASE1:Hg19::chr10:73648356..73648408,-#_593cd7f34197bfcbfd65d679d1b79539p@chr10:73648356..73648408, -
1.48e-80FFCP PHASE2:Hg19::chr6:163836917..163836950,-#_f6983995631eaaeb81557084165a51eep@chr6:163836917..163836950, -
1.48e-80FFCP PHASE1:Hg19::chr6:163836917..163836950,-#_f6983995631eaaeb81557084165a51eep@chr6:163836917..163836950, -
2.43e-80FFCP PHASE2:Hg19::chr9:19230548..19230598,+#_d05383d5265ac9ba9529da54a04619a4p@chr9:19230548..19230598, +
2.43e-80FFCP PHASE1:Hg19::chr9:19230548..19230598,+#_d05383d5265ac9ba9529da54a04619a4p@chr9:19230548..19230598, +
8.18e-80FFCP PHASE2:Hg19::chr2:145276939..145276960,+#_a0b967a60d545f0c3d15ca9530403e8dp2@ZEB2-AS1
8.18e-80FFCP PHASE1:Hg19::chr2:145276939..145276960,+#_a0b967a60d545f0c3d15ca9530403e8dp2@ZEB2-AS1
8.22e-80FFCP PHASE2:Hg19::chr12:51402938..51402955,-#_57db0174e9a3e57db5e7b344a15a2490p7@SLC11A2
8.22e-80FFCP PHASE1:Hg19::chr12:51402938..51402955,-#_57db0174e9a3e57db5e7b344a15a2490p7@SLC11A2
8.44e-80FFCP PHASE1:Hg19::chrX:37664331..37664352,+#_67c99957d0161a874636e5406b3eec99p@chrX:37664331..37664352, +
8.44e-80FFCP PHASE2:Hg19::chrX:37664331..37664352,+#_67c99957d0161a874636e5406b3eec99p@chrX:37664331..37664352, +
1.12e-79FFCP PHASE2:Hg19::chrX:153286067..153286101,-#_e75226b7dc536fda2f7dd645fc9f0acep@chrX:153286067..153286101, -
1.12e-79FFCP PHASE1:Hg19::chrX:153286067..153286101,-#_e75226b7dc536fda2f7dd645fc9f0acep@chrX:153286067..153286101, -
1.21e-79FFCP PHASE1:Hg19::chr8:116588888..116588904,+#_a23a22e809e8a13198857ef35644b77bp@chr8:116588888..116588904, +
1.21e-79FFCP PHASE2:Hg19::chr8:116588888..116588904,+#_a23a22e809e8a13198857ef35644b77bp@chr8:116588888..116588904, +
1.25e-79FFCP PHASE1:Hg19::chr1:145610717..145610730,+#_d0d77a4699850320096a1755e22160c3p4@RNF115
1.25e-79FFCP PHASE2:Hg19::chr1:145610717..145610730,+#_d0d77a4699850320096a1755e22160c3p4@RNF115
1.7e-79FFCP PHASE2:Hg19::chr19:18285973..18285996,+#_ae12c45630b43e16de9d291361c79c59p@chr19:18285973..18285996, +
1.7e-79FFCP PHASE1:Hg19::chr19:18285973..18285996,+#_ae12c45630b43e16de9d291361c79c59p@chr19:18285973..18285996, +
2.0e-79FFCP PHASE2:Hg19::chr2:129283966..129283970,+#_76db8c75c2458cc9f980c3a6d8ff31d9p@chr2:129283966..129283970, +
2.0e-79FFCP PHASE1:Hg19::chr2:129283966..129283970,+#_76db8c75c2458cc9f980c3a6d8ff31d9p@chr2:129283966..129283970, +
2.34e-79FFCP PHASE1:Hg19::chr1:150724282..150724308,-#_3f2e492256b15ff9f0d20d33b1265408p8@CTSS
2.34e-79FFCP PHASE2:Hg19::chr1:150724282..150724308,-#_3f2e492256b15ff9f0d20d33b1265408p8@CTSS
2.51e-79FFCP PHASE2:Hg19::chr17:4643027..4643036,-#_a995b8bf3c77f369304ec246cffdf37cp10@CXCL16
2.51e-79FFCP PHASE1:Hg19::chr17:4643027..4643036,-#_a995b8bf3c77f369304ec246cffdf37cp10@CXCL16
3.43e-79FFCP PHASE2:Hg19::chr1:26602990..26603008,+#_60a1b9c0b92ee80d3f1334e0019ba680p@chr1:26602990..26603008, +
3.43e-79FFCP PHASE1:Hg19::chr1:26602990..26603008,+#_60a1b9c0b92ee80d3f1334e0019ba680p@chr1:26602990..26603008, +

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