MCL coexpression mm9:478

Phase1 CAGE Peaks

	Short description
Mm9::chr10:19399797..19399799,+	p@chr10:19399797..19399799 +
Mm9::chr11:8445343..8445345,+	p@chr11:8445343..8445345 +
Mm9::chr12:91668902..91668912,+	p@chr12:91668902..91668912 +
Mm9::chr13:101017287..101017298,-	p1@Naip5
Mm9::chr13:91238101..91238106,+	p@chr13:91238101..91238106 +
Mm9::chr18:54586672..54586676,+	p@chr18:54586672..54586676 +
Mm9::chr18:82501736..82501745,-	p@chr18:82501736..82501745 -
Mm9::chr1:176260649..176260652,+	p1@1810030J14Rik p1@LOC100503310
Mm9::chr1:83832601..83832602,+	p@chr1:83832601..83832602 +
Mm9::chr2:81509850..81509853,+	p@chr2:81509850..81509853 +
Mm9::chr7:147539463..147539468,+	p@chr7:147539463..147539468 +
Mm9::chr7:28886273..28886282,+	p13@Fcgbp
Mm9::chr8:22224074..22224079,+	p1@Defa25 p1@Gm15299
Mm9::chr8:22583676..22583680,+	p1@ENSMUST00000121849
Mm9::chr8:22832496..22832497,+	p1@ENSMUST00000121649

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007339	binding of sperm to zona pellucida	0.0363964490813327
GO:0035036	sperm-egg recognition	0.0363964490813327
GO:0009988	cell-cell recognition	0.0363964490813327
GO:0007338	single fertilization	0.0468551383576859
GO:0008037	cell recognition	0.0468551383576859
GO:0009566	fertilization	0.0468551383576859

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
brush border epithelial cell	5.44e-17	6
gut absorptive cell	5.44e-17	6
absorptive cell	5.44e-17	6
enterocyte	5.44e-17	6
columnar/cuboidal epithelial cell	1.31e-14	7
intestinal epithelial cell	2.00e-11	9
epithelial cell of alimentary canal	2.00e-11	9
endo-epithelial cell	6.12e-07	15

Uber Anatomy

Ontology term	p-value	n
mucosa	2.99e-33	15
intestine	2.44e-23	31
intestinal mucosa	4.12e-23	13
anatomical wall	4.12e-23	13
wall of intestine	4.12e-23	13
gastrointestinal system mucosa	4.12e-23	13
organ component layer	1.75e-20	24
ileal mucosa	1.72e-19	3
ileum	1.72e-19	3
mucosa of small intestine	1.72e-19	3
wall of small intestine	1.72e-19	3
gastrointestinal system	5.27e-15	47
small intestine	8.80e-15	4
gut-associated lymphoid tissue	3.90e-14	2
mucosa-associated lymphoid tissue	3.90e-14	2
lymphoid tissue	3.90e-14	2
epithelium of mucosa	2.00e-11	9
gastrointestinal system epithelium	2.00e-11	9
intestinal epithelium	2.00e-11	9
lymphoid system	9.97e-10	3
simple columnar epithelium	2.16e-09	11
egg chamber	6.29e-08	1
digestive system	7.76e-08	116
digestive tract	7.76e-08	116
primitive gut	7.76e-08	116
endoderm-derived structure	1.12e-07	118
endoderm	1.12e-07	118
presumptive endoderm	1.12e-07	118

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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