MCL coexpression mm9:2174

Phase1 CAGE Peaks

	Short description
Mm9::chr16:29541470..29541495,-	p2@Atp13a4
Mm9::chr2:110561630..110561647,+	p2@Muc15
Mm9::chr2:110571707..110571718,+	p@chr2:110571707..110571718 +
Mm9::chr7:86293901..86293915,-	p1@Mfge8

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008429	phosphatidylethanolamine binding	0.0155299915344662
GO:0001786	phosphatidylserine binding	0.0155299915344662
GO:0006910	phagocytosis, recognition	0.0275892129910274
GO:0006911	phagocytosis, engulfment	0.0275892129910274
GO:0050766	positive regulation of phagocytosis	0.0275892129910274
GO:0050764	regulation of phagocytosis	0.0275892129910274
GO:0045807	positive regulation of endocytosis	0.028442021337754
GO:0005178	integrin binding	0.028442021337754
GO:0051050	positive regulation of transport	0.0322709021062711
GO:0030100	regulation of endocytosis	0.0322709021062711
GO:0006909	phagocytosis	0.0322709021062711
GO:0007338	single fertilization	0.0322709021062711
GO:0008037	cell recognition	0.0322709021062711
GO:0009566	fertilization	0.0322709021062711
GO:0032403	protein complex binding	0.0322709021062711
GO:0019897	extrinsic to plasma membrane	0.0322709021062711
GO:0019898	extrinsic to membrane	0.0418705503834012
GO:0051049	regulation of transport	0.0481014166799778

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
epithelial bud	3.60e-10	17
lung	6.46e-09	14
respiratory tube	6.46e-09	14
respiration organ	6.46e-09	14
pair of lungs	6.46e-09	14
lung primordium	6.46e-09	14
lung bud	6.46e-09	14
epithelial fold	5.40e-08	20
thoracic cavity element	9.72e-07	17
thoracic segment organ	9.72e-07	17
thoracic cavity	9.72e-07	17
thoracic segment of trunk	9.72e-07	17
respiratory primordium	9.72e-07	17
endoderm of foregut	9.72e-07	17

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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