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Coexpression cluster:C3225

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Full id: C3225_Endothelial_Neural_Lymphatic_Aortic_aorta_Whole_ductus



Phase1 CAGE Peaks

Hg19::chr12:105889929..105889933,+p@chr12:105889929..105889933
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Hg19::chr12:105962745..105962748,+p@chr12:105962745..105962748
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Hg19::chr16:82788994..82789018,+p@chr16:82788994..82789018
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
lymphatic vessel1.15e-268
lymph vasculature1.15e-268
lymphatic part of lymphoid system1.15e-268
blood vessel endothelium2.02e-2218
endothelium2.02e-2218
cardiovascular system endothelium2.02e-2218
lymphoid system2.55e-2110
vessel6.51e-1968
simple squamous epithelium3.26e-1822
umbilical vein3.13e-165
vasculature3.38e-1678
vascular system3.38e-1678
squamous epithelium6.12e-1625
vein1.58e-159
venous blood vessel1.58e-159
venous system1.58e-159
cardiovascular system8.31e-13109
circulatory system2.13e-12112
vas deferens8.91e-101
spermatic cord8.91e-101
umbilical blood vessel3.01e-099
endothelial tube5.37e-099
arterial system endothelium5.37e-099
endothelium of artery5.37e-099
splanchnic layer of lateral plate mesoderm1.43e-0883
epithelial tube open at both ends3.47e-0859
blood vessel3.47e-0859
blood vasculature3.47e-0859
vascular cord3.47e-0859


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.