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Coexpression cluster:C3743

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Full id: C3743_Smooth_Fibroblast_clear_basal_normal_sacrococcigeal_Preadipocyte



Phase1 CAGE Peaks

Hg19::chr18:9334755..9334778,+p2@TWSG1
Hg19::chr18:9334786..9334844,+p1@TWSG1
Hg19::chr18:9334857..9334871,+p3@TWSG1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
somite7.01e-1883
paraxial mesoderm7.01e-1883
presomitic mesoderm7.01e-1883
presumptive segmental plate7.01e-1883
trunk paraxial mesoderm7.01e-1883
presumptive paraxial mesoderm7.01e-1883
multilaminar epithelium8.95e-1582
dermomyotome1.30e-1470
trunk mesenchyme8.07e-14143
trunk2.28e-13216
skeletal muscle tissue7.84e-1361
striated muscle tissue7.84e-1361
myotome7.84e-1361
organism subdivision8.14e-13365
muscle tissue9.33e-1363
musculature9.33e-1363
musculature of body9.33e-1363
unilaminar epithelium7.22e-12138
surface structure8.77e-1295
vasculature2.17e-1179
vascular system2.17e-1179
multi-cellular organism6.32e-11659
splanchnic layer of lateral plate mesoderm2.96e-1084
mesenchyme2.59e-09238
entire embryonic mesenchyme2.59e-09238
integument6.03e-0945
integumental system6.03e-0945
artery6.17e-0942
arterial blood vessel6.17e-0942
arterial system6.17e-0942
blood vessel7.84e-0960
epithelial tube open at both ends7.84e-0960
blood vasculature7.84e-0960
vascular cord7.84e-0960
vessel1.91e-0869
multi-tissue structure2.07e-08347
systemic artery2.14e-0833
systemic arterial system2.14e-0833
skin of body9.19e-0840
cardiovascular system1.40e-07110
anatomical system2.63e-07625
anatomical group3.76e-07626
circulatory system4.72e-07113
epithelial tube7.19e-07118


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.