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Coexpression cluster:C81

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Full id: C81_trachea_salivary_throat_aorta_eye_submaxillary_parotid



Phase1 CAGE Peaks


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004745retinol dehydrogenase activity0.0166457643408104
GO:0001539ciliary or flagellar motility0.0166457643408104
GO:0004022alcohol dehydrogenase activity0.0166457643408104
GO:0005858axonemal dynein complex0.0166457643408104
GO:0044447axoneme part0.0166457643408104
GO:0005930axoneme0.0249902617576458
GO:0006664glycolipid metabolic process0.0454098234236558
GO:0042995cell projection0.0485879495834678
GO:0019861flagellum0.0485879495834678
GO:0030855epithelial cell differentiation0.0490211584529905
GO:0008917lipopolysaccharide N-acetylglucosaminyltransferase activity0.0493445582636681
GO:0008457beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity0.0493445582636681



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
open tracheal system trachea4.13e-282
throat8.13e-282
lower lobe of right lung8.17e-151
right lung lobe8.17e-151
lower lobe of lung8.17e-151
lobe of lung8.17e-151
right lung8.17e-151
epididymis2.41e-141
tonsil3.15e-141
mucosa-associated lymphoid tissue3.15e-141
lymphoid tissue3.15e-141
tonsillar ring3.15e-141
thoracic cavity element6.56e-1034
thoracic cavity6.56e-1034
thoracic segment organ1.27e-0935
respiratory primordium7.38e-0938
endoderm of foregut7.38e-0938
trachea1.01e-087
respiratory airway1.01e-087
respiratory tract1.24e-0854
adult organism1.82e-08114


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.11.7599e-14
MA0004.10.226021
MA0006.10.00433269
MA0007.10.0417359
MA0009.10.760206
MA0014.15.70256e-09
MA0017.10.591761
MA0019.10.139179
MA0024.10.449217
MA0025.12.72898
MA0027.11.08746
MA0028.10.000591349
MA0029.10.0766364
MA0030.14.42546
MA0031.12.71537
MA0038.10.0819849
MA0040.11.04565
MA0041.11.02685
MA0042.12.70621
MA0043.11.43955
MA0046.10.471608
MA0048.10.000138932
MA0050.10.0466807
MA0051.10.0776062
MA0052.10.0829429
MA0055.10.219373
MA0056.10
MA0057.13.70846e-06
MA0058.10.314263
MA0059.10.229494
MA0060.10.00164689
MA0061.10.00124389
MA0063.10
MA0066.10.624842
MA0067.10.287302
MA0068.10.00349068
MA0069.10.267893
MA0070.10.120361
MA0071.10.595661
MA0072.10.00788531
MA0073.10
MA0074.10.017431
MA0076.14.98433e-05
MA0077.11.24397
MA0078.11.1644
MA0081.10.165193
MA0083.10.150341
MA0084.10.991879
MA0087.11.27011
MA0088.10.00426465
MA0089.10
MA0090.10.0857234
MA0091.11.31037
MA0092.10.639994
MA0093.10.358747
MA0095.10
MA0098.10
MA0100.11.63295
MA0101.10.00537976
MA0103.11.67423
MA0105.10.000242952
MA0106.10.839402
MA0107.10.00501293
MA0108.21.53708
MA0109.10
MA0111.10.161962
MA0113.10.535932
MA0114.10.305317
MA0115.11.22344
MA0116.10.0103995
MA0117.10.0691354
MA0119.10.177433
MA0122.10.403499
MA0124.10.175475
MA0125.10.113246
MA0130.10
MA0131.10.00326717
MA0132.10
MA0133.10
MA0135.10.34267
MA0136.10.84868
MA0139.10.00589273
MA0140.10.00303519
MA0141.13.57323
MA0142.10.800085
MA0143.10.381323
MA0144.10.97977
MA0145.10.124338
MA0146.11.11285e-08
MA0147.10.00665197
MA0148.12.35857
MA0149.10.00061128
MA0062.21.58812e-05
MA0035.20.313276
MA0039.22.7e-11
MA0138.20.510554
MA0002.22.46248
MA0137.21.0123
MA0104.20.000790316
MA0047.23.54556
MA0112.20.649481
MA0065.20.000929008
MA0150.10.0770415
MA0151.10
MA0152.10.790333
MA0153.11.11526
MA0154.11.77016
MA0155.10.000254125
MA0156.10.606833
MA0157.12.15035
MA0158.10
MA0159.10.245123
MA0160.10.481673
MA0161.10
MA0162.14.1929e-13
MA0163.14.26233e-14
MA0164.10.0215609
MA0080.20.811034
MA0018.20.0746891
MA0099.20.617433
MA0079.20
MA0102.20.194619
MA0258.10.623268
MA0259.10.00250218
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data