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Coexpression cluster:C2107

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Full id: C2107_Fibroblast_Preadipocyte_mesenchymal_Chondrocyte_glioblastoma_Saos2_Smooth



Phase1 CAGE Peaks

Hg19::chr11:121972870..121972938,-p5@MIR100HG
Hg19::chr15:33021589..33021598,+p@chr15:33021589..33021598
+
Hg19::chr1:240726634..240726648,-p@chr1:240726634..240726648
-
Hg19::chr3:194090463..194090479,-p1@LRRC15


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
organism subdivision8.05e-19365
somite1.19e-1683
paraxial mesoderm1.19e-1683
presomitic mesoderm1.19e-1683
presumptive segmental plate1.19e-1683
trunk paraxial mesoderm1.19e-1683
presumptive paraxial mesoderm1.19e-1683
dermomyotome4.80e-1470
muscle tissue3.87e-1263
musculature3.87e-1263
musculature of body3.87e-1263
skeletal muscle tissue4.15e-1261
striated muscle tissue4.15e-1261
myotome4.15e-1261
multi-cellular organism5.35e-12659
multilaminar epithelium7.86e-1282
integument3.25e-1145
integumental system3.25e-1145
skin of body1.25e-0940
surface structure1.69e-0995
multi-tissue structure4.83e-09347
anatomical system1.04e-08625
anatomical group1.12e-08626
artery7.35e-0842
arterial blood vessel7.35e-0842
arterial system7.35e-0842
cell layer1.07e-07312
epithelium1.33e-07309
trunk mesenchyme1.37e-07143
systemic artery1.63e-0733
systemic arterial system1.63e-0733
splanchnic layer of lateral plate mesoderm3.62e-0784
anterior region of body6.30e-07129
craniocervical region6.30e-07129
Disease
Ontology termp-valuen
ovarian cancer2.45e-0714


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.