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Coexpression cluster:C80

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Full id: C80_immature_migratory_CD14_Dendritic_splenic_cord_Mast



Phase1 CAGE Peaks

Hg19::chr10:102793235..102793236,-p@chr10:102793235..102793236
-
Hg19::chr10:134040859..134040862,-p@chr10:134040859..134040862
-
Hg19::chr10:81032358..81032377,+p@chr10:81032358..81032377
+
Hg19::chr10:81695119..81695120,+p@chr10:81695119..81695120
+
Hg19::chr10:95326623..95326652,+p3@O3FAR1
Hg19::chr10:97149777..97149788,-p@chr10:97149777..97149788
-
Hg19::chr10:97149832..97149851,-p@chr10:97149832..97149851
-
Hg19::chr10:97457378..97457404,+p@chr10:97457378..97457404
+
Hg19::chr11:109958698..109958703,-p@chr11:109958698..109958703
-
Hg19::chr11:109958732..109958742,-p@chr11:109958732..109958742
-
Hg19::chr11:109958770..109958780,-p@chr11:109958770..109958780
-
Hg19::chr11:109959078..109959102,+p@chr11:109959078..109959102
+
Hg19::chr11:109959207..109959223,+p@chr11:109959207..109959223
+
Hg19::chr11:109959243..109959256,+p@chr11:109959243..109959256
+
Hg19::chr11:109959270..109959281,+p@chr11:109959270..109959281
+
Hg19::chr11:109963272..109963287,+p13@ZC3H12C
Hg19::chr11:109963681..109963715,+p5@ZC3H12C
Hg19::chr11:109963716..109963724,+p19@ZC3H12C
Hg19::chr11:117805926..117805937,+p@chr11:117805926..117805937
+
Hg19::chr11:12228326..12228332,+p@chr11:12228326..12228332
+
Hg19::chr11:12229172..12229186,+p9@MICAL2
Hg19::chr11:12263827..12263838,+p29@MICAL2
Hg19::chr11:12263846..12263853,+p43@MICAL2
Hg19::chr12:102174476..102174482,-p@chr12:102174476..102174482
-
Hg19::chr12:112590221..112590232,+p@chr12:112590221..112590232
+
Hg19::chr12:113573495..113573579,-p1@RASAL1
Hg19::chr12:113590909..113590922,+p4@CCDC42B
Hg19::chr12:122242766..122242781,+p8@SETD1B
Hg19::chr12:123205705..123205747,+p@chr12:123205705..123205747
+
Hg19::chr12:131576196..131576201,+p9@GPR133
Hg19::chr12:131590635..131590638,+p@chr12:131590635..131590638
+
Hg19::chr12:133005734..133005763,-p@chr12:133005734..133005763
-
Hg19::chr12:322510..322551,-p17@SLC6A12
Hg19::chr12:323920..323928,+p@chr12:323920..323928
+
Hg19::chr12:77314238..77314249,-p@chr12:77314238..77314249
-
Hg19::chr12:95211957..95211972,-p@chr12:95211957..95211972
-
Hg19::chr12:95264953..95264971,-p@chr12:95264953..95264971
-
Hg19::chr12:96649259..96649290,+p9@ELK3
Hg19::chr13:100018656..100018672,+p@chr13:100018656..100018672
+
Hg19::chr13:111855399..111855413,+p4@ARHGEF7
Hg19::chr13:111855414..111855417,+p21@ARHGEF7
Hg19::chr13:29315407..29315417,+p@chr13:29315407..29315417
+
Hg19::chr13:42969602..42969625,-p@chr13:42969602..42969625
-
Hg19::chr13:75873698..75873705,-p@chr13:75873698..75873705
-
Hg19::chr13:75873956..75873959,-p@chr13:75873956..75873959
-
Hg19::chr13:75884255..75884262,-p@chr13:75884255..75884262
-
Hg19::chr13:75884363..75884374,-p@chr13:75884363..75884374
-
Hg19::chr13:75884379..75884384,-p@chr13:75884379..75884384
-
Hg19::chr13:75884392..75884395,-p@chr13:75884392..75884395
-
Hg19::chr13:75884400..75884416,-p@chr13:75884400..75884416
-
Hg19::chr13:75884448..75884459,-p@chr13:75884448..75884459
-
Hg19::chr13:99959625..99959636,-p3@GPR183
Hg19::chr13:99959671..99959686,-p2@GPR183
Hg19::chr14:67878918..67878936,-p2@PLEK2
Hg19::chr14:67878948..67878953,-p4@PLEK2
Hg19::chr15:31696853..31696856,+p@chr15:31696853..31696856
+
Hg19::chr15:50411908..50411922,-p6@ATP8B4
Hg19::chr15:86125028..86125038,+p52@AKAP13
Hg19::chr15:86125058..86125067,+p69@AKAP13
Hg19::chr16:10960056..10960069,+p1@AB463580
Hg19::chr16:3647506..3647511,-p@chr16:3647506..3647511
-
Hg19::chr17:1576806..1576810,-p@chr17:1576806..1576810
-
Hg19::chr17:30002739..30002743,-p@chr17:30002739..30002743
-
Hg19::chr17:37880326..37880328,-p@chr17:37880326..37880328
-
Hg19::chr17:55693327..55693338,+p@chr17:55693327..55693338
+
Hg19::chr17:76136828..76136842,+p2@TMC8
Hg19::chr17:817943..817953,-p@chr17:817943..817953
-
Hg19::chr18:13611885..13611899,+p6@C18orf1
Hg19::chr18:13611909..13611923,+p10@C18orf1
Hg19::chr18:22537624..22537627,-p@chr18:22537624..22537627
-
Hg19::chr18:46523734..46523740,+p@chr18:46523734..46523740
+
Hg19::chr18:53545759..53545802,+p@chr18:53545759..53545802
+
Hg19::chr19:10515604..10515629,+p@chr19:10515604..10515629
+
Hg19::chr19:10531150..10531237,+p3@PDE4A
Hg19::chr19:2085219..2085230,-p10@MOB3A
Hg19::chr19:35481583..35481590,-p@chr19:35481583..35481590
-
Hg19::chr19:35485281..35485283,+p20@GRAMD1A
Hg19::chr19:35485440..35485460,+p13@GRAMD1A
Hg19::chr19:35485484..35485496,+p16@GRAMD1A
Hg19::chr19:36393258..36393271,+p6@HCST
Hg19::chr19:38085954..38085963,-p12@ZNF571
Hg19::chr19:51830316..51830333,+p@chr19:51830316..51830333
+
Hg19::chr19:59055602..59055605,+p17@TRIM28
Hg19::chr1:114448027..114448070,+p2@DCLRE1B
Hg19::chr1:117087402..117087404,+p@chr1:117087402..117087404
+
Hg19::chr1:157952996..157953024,+p@chr1:157952996..157953024
+
Hg19::chr1:158224204..158224231,+p1@CD1A
Hg19::chr1:158224254..158224274,+p5@CD1A
Hg19::chr1:158224278..158224289,+p9@CD1A
Hg19::chr1:183442432..183442460,+p@chr1:183442432..183442460
+
Hg19::chr1:192458942..192458949,-p@chr1:192458942..192458949
-
Hg19::chr1:192578585..192578597,+p@chr1:192578585..192578597
+
Hg19::chr1:19578116..19578131,+p4@MRTO4
Hg19::chr1:19578147..19578153,+p6@MRTO4
Hg19::chr1:201376546..201376550,+p@chr1:201376546..201376550
+
Hg19::chr1:206756587..206756605,+p8@RASSF5
Hg19::chr1:206756636..206756643,+p23@RASSF5
Hg19::chr1:206756646..206756652,+p21@RASSF5
Hg19::chr1:219632969..219632980,-p@chr1:219632969..219632980
-
Hg19::chr1:229182494..229182507,-p@chr1:229182494..229182507
-
Hg19::chr1:229182544..229182560,-p@chr1:229182544..229182560
-
Hg19::chr1:229182571..229182583,-p@chr1:229182571..229182583
-
Hg19::chr1:25291461..25291472,-p11@RUNX3
Hg19::chr1:25291475..25291511,-p2@RUNX3
Hg19::chr1:42619540..42619567,+p@chr1:42619540..42619567
+
Hg19::chr1:6341268..6341339,-p@chr1:6341268..6341339
-
Hg19::chr1:762210..762220,+p@chr1:762210..762220
+
Hg19::chr1:763094..763106,+p1@ENST00000416570
Hg19::chr1:85462749..85462760,-p3@MCOLN2
Hg19::chr1:85462762..85462804,-p1@MCOLN2
Hg19::chr1:85462813..85462824,-p2@MCOLN2
Hg19::chr20:44639404..44639426,+p@chr20:44639404..44639426
+
Hg19::chr20:44639498..44639509,+p@chr20:44639498..44639509
+
Hg19::chr20:44639714..44639732,+p@chr20:44639714..44639732
+
Hg19::chr20:44639733..44639737,+p@chr20:44639733..44639737
+
Hg19::chr20:44640603..44640610,+p8@MMP9
Hg19::chr20:44640676..44640696,+p6@MMP9
Hg19::chr20:44640717..44640734,+p5@MMP9
Hg19::chr20:62482031..62482052,-p@chr20:62482031..62482052
-
Hg19::chr21:19165749..19165765,+p2@CHODL
Hg19::chr21:46285621..46285636,-p12@PTTG1IP
Hg19::chr22:37260997..37261033,+p@chr22:37260997..37261033
+
Hg19::chr22:43366166..43366179,-p@chr22:43366166..43366179
-
Hg19::chr2:102758751..102758779,+p15@IL1R1
Hg19::chr2:102760015..102760032,+p1@CR936696
Hg19::chr2:102803477..102803511,+p1@IL1RL2
Hg19::chr2:128146426..128146444,+p2@ENST00000433673
Hg19::chr2:128146510..128146519,+p4@ENST00000433673
Hg19::chr2:128405655..128405692,+p5@GPR17
Hg19::chr2:128408404..128408428,-p34@LIMS2
Hg19::chr2:135532029..135532035,-p@chr2:135532029..135532035
-
Hg19::chr2:135821386..135821432,+p@chr2:135821386..135821432
+
Hg19::chr2:191756900..191756912,+p@chr2:191756900..191756912
+
Hg19::chr2:201997651..201997669,+p39@CFLAR
Hg19::chr2:201997681..201997696,+p31@CFLAR
Hg19::chr2:204398121..204398132,-p18@RAPH1
Hg19::chr2:204398141..204398180,-p7@RAPH1
Hg19::chr2:235214861..235214870,+p@chr2:235214861..235214870
+
Hg19::chr2:235217777..235217792,+p@chr2:235217777..235217792
+
Hg19::chr2:235218388..235218394,+p@chr2:235218388..235218394
+
Hg19::chr2:235311862..235311891,-p@chr2:235311862..235311891
-
Hg19::chr2:235312015..235312040,+p@chr2:235312015..235312040
+
Hg19::chr2:238807387..238807393,-p@chr2:238807387..238807393
-
Hg19::chr2:242169465..242169480,-p68@HDLBP
Hg19::chr2:242169538..242169541,-p71@HDLBP
Hg19::chr2:2725835..2725840,-p@chr2:2725835..2725840
-
Hg19::chr2:61081135..61081167,+p@chr2:61081135..61081167
+
Hg19::chr2:61108878..61108891,+p5@REL
Hg19::chr2:61110552..61110562,+p@chr2:61110552..61110562
+
Hg19::chr2:64552666..64552692,-p@chr2:64552666..64552692
-
Hg19::chr2:65593758..65593771,-p9@SPRED2
Hg19::chr2:65593786..65593817,-p8@SPRED2
Hg19::chr2:70780545..70780558,-p4@TGFA
Hg19::chr2:70780572..70780583,-p6@TGFA
Hg19::chr2:71056916..71056934,+p@chr2:71056916..71056934
+
Hg19::chr2:71062938..71062952,-p1@CD207
Hg19::chr2:8724165..8724187,+p@chr2:8724165..8724187
+
Hg19::chr2:8724189..8724204,+p@chr2:8724189..8724204
+
Hg19::chr3:119182394..119182405,-p9@TMEM39A
Hg19::chr3:119188104..119188112,-p15@TMEM39A
Hg19::chr3:119188119..119188129,-p18@TMEM39A
Hg19::chr3:119188142..119188154,-p6@TMEM39A
Hg19::chr3:197687656..197687667,+p@chr3:197687656..197687667
+
Hg19::chr3:5068581..5068590,+p@chr3:5068581..5068590
+
Hg19::chr3:7961529..7961534,-p@chr3:7961529..7961534
-
Hg19::chr3:7961538..7961548,-p@chr3:7961538..7961548
-
Hg19::chr4:100737885..100737901,+p2@DAPP1
Hg19::chr4:103514596..103514605,+p44@NFKB1
Hg19::chr4:103514644..103514652,+p45@NFKB1
Hg19::chr4:148605150..148605161,-p5@PRMT10
Hg19::chr4:148605163..148605168,-p9@PRMT10
Hg19::chr4:148605177..148605178,-p10@PRMT10
Hg19::chr4:148605203..148605214,-p7@PRMT10
Hg19::chr4:148605219..148605264,-p2@PRMT10
Hg19::chr4:152330409..152330416,+p5@FAM160A1
Hg19::chr4:3372015..3372020,+p33@RGS12
Hg19::chr4:84457529..84457541,+p8@AGPAT9
Hg19::chr4:84457628..84457666,+p3@AGPAT9
Hg19::chr4:84495829..84495833,+p@chr4:84495829..84495833
+
Hg19::chr5:125695881..125695907,+p18@GRAMD3
Hg19::chr5:125695908..125695916,+p38@GRAMD3
Hg19::chr5:125695985..125695996,+p19@GRAMD3
Hg19::chr5:146381093..146381133,+p@chr5:146381093..146381133
+
Hg19::chr5:14664896..14664901,+p12@FAM105B
Hg19::chr5:14664913..14664916,+p10@FAM105B
Hg19::chr5:14664971..14664983,+p7@FAM105B
Hg19::chr5:14668684..14668705,+p@chr5:14668684..14668705
+
Hg19::chr5:14993035..14993045,+p@chr5:14993035..14993045
+
Hg19::chr5:446253..446280,+p4@EXOC3
Hg19::chr6:10529918..10529924,+p31@GCNT2
Hg19::chr6:10529946..10529970,+p7@GCNT2
Hg19::chr6:10529983..10530000,+p13@GCNT2
Hg19::chr6:116989837..116989843,-p2@ZUFSP
Hg19::chr6:123038689..123038700,+p8@PKIB
Hg19::chr6:149806523..149806601,-p3@ZC3H12D
Hg19::chr6:16700759..16700768,-p@chr6:16700759..16700768
-
Hg19::chr6:167536616..167536629,+p7@CCR6
Hg19::chr6:169588737..169588744,-p@chr6:169588737..169588744
-
Hg19::chr6:169770365..169770377,-p@chr6:169770365..169770377
-
Hg19::chr6:32726761..32726781,-p@chr6:32726761..32726781
-
Hg19::chr6:32729529..32729536,-p3@M95729
Hg19::chr6:32731284..32731295,-p2@HLA-DQB2
Hg19::chr6:32731299..32731316,-p1@HLA-DQB2
Hg19::chr6:32731327..32731340,-p3@HLA-DQB2
Hg19::chr6:32782930..32782943,-p@chr6:32782930..32782943
-
Hg19::chr6:33041605..33041651,-p9@HLA-DPA1
Hg19::chr6:33084930..33084937,+p@chr6:33084930..33084937
+
Hg19::chr6:4337610..4337616,+p@chr6:4337610..4337616
+
Hg19::chr6:4778354..4778387,-p@chr6:4778354..4778387
-
Hg19::chr6:6841284..6841289,+p@chr6:6841284..6841289
+
Hg19::chr7:106681868..106681884,+p@chr7:106681868..106681884
+
Hg19::chr7:111726607..111726620,-p@chr7:111726607..111726620
-
Hg19::chr7:111726632..111726641,-p@chr7:111726632..111726641
-
Hg19::chr7:151182048..151182088,-p@chr7:151182048..151182088
-
Hg19::chr7:20345503..20345510,+p1@ENST00000455373
Hg19::chr7:20346998..20347015,+p@chr7:20346998..20347015
+
Hg19::chr7:20479783..20479785,-p@chr7:20479783..20479785
-
Hg19::chr7:45025791..45025805,-p3@SNHG15
Hg19::chr7:45025815..45025835,-p5@SNHG15
Hg19::chr7:73985353..73985386,+p@chr7:73985353..73985386
+
Hg19::chr8:118169907..118169924,+p@chr8:118169907..118169924
+
Hg19::chr8:120974832..120974840,+p@chr8:120974832..120974840
+
Hg19::chr8:144261092..144261101,-p@chr8:144261092..144261101
-
Hg19::chr8:21039080..21039110,+p@chr8:21039080..21039110
+
Hg19::chr8:39806500..39806509,+p7@IDO2
Hg19::chr8:39806514..39806522,+p3@IDO2
Hg19::chr9:124260983..124260993,-p@chr9:124260983..124260993
-
Hg19::chr9:134505689..134505701,-p@chr9:134505689..134505701
-
Hg19::chr9:134505710..134505715,-p@chr9:134505710..134505715
-
Hg19::chr9:137277968..137277982,+p@chr9:137277968..137277982
+
Hg19::chr9:140565510..140565515,-p@chr9:140565510..140565515
-
Hg19::chr9:16130228..16130236,+p@chr9:16130228..16130236
+
Hg19::chr9:72874205..72874219,-p2@LOC100507299
Hg19::chr9:8384123..8384141,-p@chr9:8384123..8384141
-
Hg19::chr9:8384143..8384151,-p@chr9:8384143..8384151
-
Hg19::chr9:8384168..8384183,-p@chr9:8384168..8384183
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0016020membrane0.000105235823592114
GO:0007165signal transduction0.000263923243027088
GO:0019967interleukin-1, Type I, activating binding0.000263923243027088
GO:0004909interleukin-1, Type I, activating receptor activity0.000263923243027088
GO:0016021integral to membrane0.000388151579910662
GO:0031224intrinsic to membrane0.000388151579910662
GO:0005886plasma membrane0.000445817853965356
GO:0007154cell communication0.000592963730833206
GO:0019955cytokine binding0.000748096547069645
GO:0009966regulation of signal transduction0.000908395813011878
GO:0044425membrane part0.00118037107450795
GO:0004908interleukin-1 receptor activity0.00244968562877753
GO:0019966interleukin-1 binding0.00362745201820771
GO:0044464cell part0.0106103564106766
GO:0032395MHC class II receptor activity0.0106103564106766
GO:0044459plasma membrane part0.0108276233204398
GO:0048522positive regulation of cellular process0.012610481102895
GO:0002504antigen processing and presentation of peptide or polysaccharide antigen via MHC class II0.0157127403102284
GO:0005887integral to plasma membrane0.0159087146232872
GO:0031226intrinsic to plasma membrane0.016347366000458
GO:0002376immune system process0.0183931877997928
GO:0048518positive regulation of biological process0.0183931877997928
GO:0050678regulation of epithelial cell proliferation0.0194577073126878
GO:0042613MHC class II protein complex0.0213494954829092
GO:0050673epithelial cell proliferation0.0216683139545059
GO:0004907interleukin receptor activity0.0221167401078648
GO:0001637G-protein chemoattractant receptor activity0.0230205144243584
GO:0004950chemokine receptor activity0.0230205144243584
GO:0019956chemokine binding0.0233857044042336
GO:0009967positive regulation of signal transduction0.0233857044042336
GO:0004229gelatinase B activity0.0233857044042336
GO:0008289lipid binding0.0233857044042336
GO:0006955immune response0.0233857044042336
GO:0019965interleukin binding0.0233857044042336
GO:0007242intracellular signaling cascade0.026418327612655
GO:0042611MHC protein complex0.0275690204112421
GO:0007243protein kinase cascade0.0295782410065911
GO:0006366transcription from RNA polymerase II promoter0.0306455066607598
GO:0032502developmental process0.0312703727157884
GO:0032422purine-rich negative regulatory element binding0.0372490842101476
GO:0019882antigen processing and presentation0.0372490842101476
GO:0006469negative regulation of protein kinase activity0.0372490842101476
GO:0033673negative regulation of kinase activity0.0372490842101476
GO:0051348negative regulation of transferase activity0.0380882760862701
GO:0019992diacylglycerol binding0.0380882760862701
GO:0005155epidermal growth factor receptor activating ligand activity0.0486580109550228
GO:0004896hematopoietin/interferon-class (D200-domain) cytokine receptor activity0.0495449646998222
GO:0004871signal transducer activity0.0496095695228863
GO:0060089molecular transducer activity0.0496095695228863
GO:0045859regulation of protein kinase activity0.0496095695228863
GO:0006968cellular defense response0.0496095695228863



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br><br>



Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
BATF#10538191.961009466329530.004315403675799550.0204880645739081
BCL11A#53335182.163771999427660.001954338054176470.0114784114295431
EBF1#1879451.698266983455950.0002793891684559920.00297412347002093
IRF4#3662201.857162092096960.006193101277547370.0273697234396483
NFKB1#4790591.372015856048460.005757644211490460.025928018446182
SPI1#6688491.703440050498360.0001309681174388420.00172290958775604



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data