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Coexpression cluster:C1722

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Full id: C1722_Nucleus_Anulus_parotid_Fibroblast_salivary_Olfactory_trachea



Phase1 CAGE Peaks

Hg19::chr14:37126141..37126157,-p@chr14:37126141..37126157
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Hg19::chr14:37126765..37126799,+p2@PAX9
Hg19::chr14:37126814..37126834,+p4@PAX9
Hg19::chr14:37126852..37126863,+p2@ENST00000555639
Hg19::chr14:37126870..37126882,+p1@ENST00000555639


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007492endoderm development0.00980219003885553



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
mouth5.34e-2828
stomodeum5.34e-2828
mixed ectoderm/mesoderm/endoderm-derived structure3.62e-2318
oral opening6.68e-1721
subdivision of head1.21e-1648
respiratory system3.52e-1572
orifice2.41e-1435
saliva-secreting gland9.35e-136
gland of oral region9.35e-136
gland of foregut9.35e-136
oral gland9.35e-136
oral cavity9.35e-136
gland of gut9.41e-1310
periodontium2.77e-126
dentition2.77e-126
endoderm-derived structure3.47e-12169
endoderm3.47e-12169
presumptive endoderm3.47e-12169
subdivision of skeletal system6.14e-1213
skeleton6.14e-1213
sclerotome6.14e-1213
digestive system2.64e-11155
digestive tract2.64e-11155
primitive gut2.64e-11155
surface structure1.12e-0995
mixed endoderm/mesoderm-derived structure1.77e-09130
skull1.53e-0811
nucleus pulposus2.08e-073
axial mesoderm2.08e-073
notochord2.08e-073
chordamesoderm2.08e-073
respiratory tract4.47e-0753
anterior region of body5.53e-07129
craniocervical region5.53e-07129


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.