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DOID:162

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Name:cancer
Namespace:FANTOM
Definition:"A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis." [stedman:rlc, url:http://en.wikipedia.org/wiki/cancer, url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book
Xrefs:
links:

ICD9CM:239.4
SNOMEDCT_2010_1_31:189535002

UMLS_CUI:C0027639
Synonyms: "malignant neoplasm" EXACT []
"malignant tumor " EXACT []
"primary cancer" EXACT []

Ontology association
Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.

link to ontology dataset
data


Parents

is_a:DOID:14566(disease of cellular proliferation)



Children


is a:DOID:0050686 (organ system cancer),DOID:0050687 (cell type cancer)


Ontology Tree: Loaded from BioPortal

FF samples

Human (Homo sapiens)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10408-106B3 (lung adenocarcinoma cell line:PC-14)
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10410-106B5 (extraskeletal myxoid chondrosarcoma cell line:H-EMC-SS)
  • 10411-106B6 (renal cell carcinoma cell line:OS-RC-2)
  • 10412-106B7 (malignant trichilemmal cyst cell line:DJM-1)
  • 10413-106B8 (glioma cell line:GI-1)
  • 10414-106B9 (maxillary sinus tumor cell line:HSQ-89)

... further results Mouse (Mus musculus)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10408-106B3 (lung adenocarcinoma cell line:PC-14)
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10410-106B5 (extraskeletal myxoid chondrosarcoma cell line:H-EMC-SS)
  • 10411-106B6 (renal cell carcinoma cell line:OS-RC-2)
  • 10412-106B7 (malignant trichilemmal cyst cell line:DJM-1)
  • 10413-106B8 (glioma cell line:GI-1)
  • 10414-106B9 (maxillary sinus tumor cell line:HSQ-89)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:162 (cancer), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
9.96e-79FFCP PHASE1:Hg19::chrX:153991088..153991168,+#_d8b0c3734cef3039c71d0551d9b5e18ap1@DKC1
9.96e-79FFCP PHASE2:Hg19::chrX:153991088..153991168,+#_d8b0c3734cef3039c71d0551d9b5e18ap1@DKC1
3.44e-74FFCP PHASE1:Hg19::chr11:1372935..1372952,+#_fd802cbbc82d54ab0bf78af791833584p@chr11:1372935..1372952, +
3.44e-74FFCP PHASE2:Hg19::chr11:1372935..1372952,+#_fd802cbbc82d54ab0bf78af791833584p@chr11:1372935..1372952, +
3.08e-67FFCP PHASE1:Hg19::chr2:197504410..197504471,+#_e9298da4595f179c91c66c17da6e7dfap1@CCDC150
3.08e-67FFCP PHASE2:Hg19::chr2:197504410..197504471,+#_e9298da4595f179c91c66c17da6e7dfap1@CCDC150
1.07e-65FFCP PHASE2:Hg19::chr17:38444115..38444194,+#_bab7d919aabe45a070d1cf235b5fbf5dp1@CDC6
1.07e-65FFCP PHASE1:Hg19::chr17:38444115..38444194,+#_bab7d919aabe45a070d1cf235b5fbf5dp1@CDC6
2.66e-65FFCP PHASE2:Hg19::chr17:41277372..41277418,-#_cbce78e758ac3c3d8ea488d5193def09p1@BRCA1
2.66e-65FFCP PHASE1:Hg19::chr17:41277372..41277418,-#_cbce78e758ac3c3d8ea488d5193def09p1@BRCA1
7.18e-65FFCP PHASE1:Hg19::chr3:179280702..179280769,+#_1a497aec0d33d0b0f0a19e36cba51db8p1@ACTL6A
7.18e-65FFCP PHASE2:Hg19::chr3:179280702..179280769,+#_1a497aec0d33d0b0f0a19e36cba51db8p1@ACTL6A
2.18e-64FFCP PHASE2:Hg19::chr1:214776516..214776565,+#_b23a7c4cde54316bdb0f4ff3873a48f2p1@CENPF
2.18e-64FFCP PHASE1:Hg19::chr1:214776516..214776565,+#_b23a7c4cde54316bdb0f4ff3873a48f2p1@CENPF
2.34e-64FFCP PHASE1:Hg19::chr20:57617831..57617909,-#_2f8d7f2ac11d92089f8cf64ea32ea01ep1@SLMO2
2.34e-64FFCP PHASE2:Hg19::chr20:57617831..57617909,-#_2f8d7f2ac11d92089f8cf64ea32ea01ep1@SLMO2
2.6e-64FFCP PHASE2:Hg19::chr8:124408630..124408647,-#_5fda194305cf9524b8765479dac01648p2@ATAD2
2.6e-64FFCP PHASE1:Hg19::chr8:124408630..124408647,-#_5fda194305cf9524b8765479dac01648p2@ATAD2
4.32e-64FFCP PHASE1:Hg19::chrX:153991175..153991226,+#_5d00841d22f38297704bc07fc3c0c6cfp2@DKC1
4.32e-64FFCP PHASE2:Hg19::chrX:153991175..153991226,+#_5d00841d22f38297704bc07fc3c0c6cfp2@DKC1
7.63e-64FFCP PHASE2:Hg19::chr7:105162652..105162709,-#_f1db6a0286e916743ee2a21ed04a8139p1@PUS7
7.63e-64FFCP PHASE1:Hg19::chr7:105162652..105162709,-#_f1db6a0286e916743ee2a21ed04a8139p1@PUS7
1.13e-63FFCP PHASE1:Hg19::chr1:154947126..154947147,+#_a15a8b5c70555bb6cab45bd2ddc8fb17p2@CKS1B
1.13e-63FFCP PHASE2:Hg19::chr1:154947126..154947147,+#_a15a8b5c70555bb6cab45bd2ddc8fb17p2@CKS1B
2.95e-63FFCP PHASE2:Hg19::chr1:154947148..154947175,+#_14ac35d2bfee7cf4d392799cb8c84045p1@CKS1B
2.95e-63FFCP PHASE1:Hg19::chr1:154947148..154947175,+#_14ac35d2bfee7cf4d392799cb8c84045p1@CKS1B
3.81e-63FFCP PHASE2:Hg19::chr8:124408652..124408712,-#_c13c877baac7f299173faf1dff1e9b20p1@ATAD2
3.81e-63FFCP PHASE1:Hg19::chr8:124408652..124408712,-#_c13c877baac7f299173faf1dff1e9b20p1@ATAD2
1.66e-62FFCP PHASE2:Hg19::chr1:214776570..214776593,+#_1093b2b699893358a8b0516c6b403362p2@CENPF
1.66e-62FFCP PHASE1:Hg19::chr1:214776570..214776593,+#_1093b2b699893358a8b0516c6b403362p2@CENPF
2.3e-62FFCP PHASE2:Hg19::chr4:57301645..57301675,-#_bfa11d4a54514d6f221f7bce9fad8712p2@PPAT
2.3e-62FFCP PHASE1:Hg19::chr4:57301645..57301675,-#_bfa11d4a54514d6f221f7bce9fad8712p2@PPAT
2.38e-62FFCP PHASE1:Hg19::chr1:211848955..211848981,-#_eba171b59f0a24c932a449db92fbfbb8p1@NEK2
2.38e-62FFCP PHASE2:Hg19::chr1:211848955..211848981,-#_eba171b59f0a24c932a449db92fbfbb8p1@NEK2
5.44e-62FFCP PHASE2:Hg19::chr17:38574169..38574180,-#_b43fc8c57b6e5112fdc9cc5993e9de98p2@TOP2A
5.44e-62FFCP PHASE1:Hg19::chr17:38574169..38574180,-#_b43fc8c57b6e5112fdc9cc5993e9de98p2@TOP2A
6.99e-62FFCP PHASE2:Hg19::chr5:34915805..34915847,+#_2bea4c8579e8ee77eeb206ed3ba1350cp1@BRIX1
6.99e-62FFCP PHASE1:Hg19::chr5:34915805..34915847,+#_2bea4c8579e8ee77eeb206ed3ba1350cp1@BRIX1
8.22e-62FFCP PHASE1:Hg19::chr3:172468505..172468582,+#_0aa2b79ecc1294441bf0699168559251p1@ECT2
8.22e-62FFCP PHASE2:Hg19::chr3:172468505..172468582,+#_0aa2b79ecc1294441bf0699168559251p1@ECT2
8.85e-62FFCP PHASE2:Hg19::chr2:198364552..198364576,-#_c29cfad6f7ecaf1fd9bdc8c56f05401bp1@HSPD1
8.85e-62FFCP PHASE1:Hg19::chr2:198364552..198364576,-#_c29cfad6f7ecaf1fd9bdc8c56f05401bp1@HSPD1
9.36e-62FFCP PHASE2:Hg19::chr12:4647995..4648087,+#_e82e53e664a9e6aca2b896a7cffc4f74p1@RAD51AP1
9.36e-62FFCP PHASE1:Hg19::chr12:4647995..4648087,+#_e82e53e664a9e6aca2b896a7cffc4f74p1@RAD51AP1
9.57e-62FFCP PHASE1:Hg19::chr11:125495862..125495882,+#_9dd1f94d374b079eaa9e41918d62bdc6p1@CHEK1
9.57e-62FFCP PHASE2:Hg19::chr11:125495862..125495882,+#_9dd1f94d374b079eaa9e41918d62bdc6p1@CHEK1
1.63e-61FFCP PHASE1:Hg19::chr12:118454500..118454585,+#_ec3bb1ab3e2c7b77f070a9a752cc84aap1@RFC5
1.63e-61FFCP PHASE2:Hg19::chr12:118454500..118454585,+#_ec3bb1ab3e2c7b77f070a9a752cc84aap1@RFC5
1.64e-61FFCP PHASE1:Hg19::chr17:38574125..38574168,-#_4676515ba606590fa409795b095ee3f1p1@TOP2A
1.64e-61FFCP PHASE2:Hg19::chr17:38574125..38574168,-#_4676515ba606590fa409795b095ee3f1p1@TOP2A
2.18e-61FFCP PHASE1:Hg19::chr7:56119449..56119492,+#_1234d05a38a605e77fd0013dd0828226p1@CCT6A
2.18e-61FFCP PHASE2:Hg19::chr7:56119449..56119492,+#_1234d05a38a605e77fd0013dd0828226p1@CCT6A
7.19e-61FFCP PHASE1:Hg19::chr5:37288836..37288849,-#_9ca35e41650acdb579efd3be2bddd47bp@chr5:37288836..37288849, -
7.19e-61FFCP PHASE2:Hg19::chr5:37288836..37288849,-#_9ca35e41650acdb579efd3be2bddd47bp@chr5:37288836..37288849, -
7.2e-61FFCP PHASE1:Hg19::chr1:242011485..242011542,+#_0064c5c08ea96464bcf816c2e12270dcp1@EXO1
7.2e-61FFCP PHASE2:Hg19::chr1:242011485..242011542,+#_0064c5c08ea96464bcf816c2e12270dcp1@EXO1
9.06e-61FFCP PHASE1:Hg19::chr10:96363899..96363904,+#_8f61d266262a5bcac520455551e38ebap@chr10:96363899..96363904, +
9.06e-61FFCP PHASE2:Hg19::chr10:96363899..96363904,+#_8f61d266262a5bcac520455551e38ebap@chr10:96363899..96363904, +
1.15e-60FFCP PHASE1:Hg19::chr2:29117521..29117569,+#_cf6b6bf6d2688af83e9d2dc7cde44f11p1@WDR43
1.15e-60FFCP PHASE2:Hg19::chr2:29117521..29117569,+#_cf6b6bf6d2688af83e9d2dc7cde44f11p1@WDR43
3.12e-60FFCP PHASE2:Hg19::chr2:70529150..70529179,-#_2348b90e0f4a82abc44b2055b92d07d2p1@FAM136A
3.12e-60FFCP PHASE1:Hg19::chr2:70529150..70529179,-#_2348b90e0f4a82abc44b2055b92d07d2p1@FAM136A
5.18e-60FFCP PHASE2:Hg19::chr8:130951991..130952083,-#_c0069b8820d5ee577d979c5b680d6b34p1@FAM49B
5.18e-60FFCP PHASE1:Hg19::chr8:130951991..130952083,-#_c0069b8820d5ee577d979c5b680d6b34p1@FAM49B
6.2e-60FFCP PHASE2:Hg19::chr5:37371163..37371231,-#_bb10e28ecc2f48ab5085148de102b8bfp1@NUP155
6.2e-60FFCP PHASE1:Hg19::chr5:37371163..37371231,-#_bb10e28ecc2f48ab5085148de102b8bfp1@NUP155
7.13e-60FFCP PHASE2:Hg19::chr18:19192235..19192337,+#_dae9cbc994193a6ff8644275dd8f6738p1@SNRPD1
7.13e-60FFCP PHASE1:Hg19::chr18:19192235..19192337,+#_dae9cbc994193a6ff8644275dd8f6738p1@SNRPD1
1.32e-59FFCP PHASE1:Hg19::chr1:68962744..68962772,-#_6ec1996ff7754008226a84bb47b8b366p1@DEPDC1
1.32e-59FFCP PHASE2:Hg19::chr1:68962744..68962772,-#_6ec1996ff7754008226a84bb47b8b366p1@DEPDC1
1.54e-59FFCP PHASE1:Hg19::chr15:40453204..40453304,+#_9fd37529bdb1fa16f012c03396fa4321p1@BUB1B
1.54e-59FFCP PHASE2:Hg19::chr15:40453204..40453304,+#_9fd37529bdb1fa16f012c03396fa4321p1@BUB1B
1.97e-59FFCP PHASE2:Hg19::chr15:41625060..41625088,+#_28c02d1a08d19c6820a441d5ad4439f2p1@NUSAP1
1.97e-59FFCP PHASE1:Hg19::chr15:41625060..41625088,+#_28c02d1a08d19c6820a441d5ad4439f2p1@NUSAP1
4.08e-59FFCP PHASE1:Hg19::chr12:57146095..57146149,-#_e0f4d3e6943a38bde428db1b8b02f915p1@PRIM1
4.08e-59FFCP PHASE2:Hg19::chr12:57146095..57146149,-#_e0f4d3e6943a38bde428db1b8b02f915p1@PRIM1
4.93e-59FFCP PHASE1:Hg19::chr15:91537809..91537824,-#_b22b28d8c476f7bce74c81601317e2a1p2@PRC1
4.93e-59FFCP PHASE2:Hg19::chr15:91537809..91537824,-#_b22b28d8c476f7bce74c81601317e2a1p2@PRC1
5.19e-59FFCP PHASE2:Hg19::chr15:89787185..89787263,+#_77c7995359dd9eb90391b080cc4e838bp1@FANCI
5.19e-59FFCP PHASE1:Hg19::chr15:89787185..89787263,+#_77c7995359dd9eb90391b080cc4e838bp1@FANCI
5.72e-59FFCP PHASE2:Hg19::chr7:152373216..152373260,-#_d4341dda3ea184ea62d141fe9c1bd306p1@XRCC2
5.72e-59FFCP PHASE1:Hg19::chr7:152373216..152373260,-#_d4341dda3ea184ea62d141fe9c1bd306p1@XRCC2
6.59e-59FFCP PHASE2:Hg19::chr4:154265825..154265875,+#_956b476bdb576b8b46ba0e905d63cb06p1@MND1
6.59e-59FFCP PHASE1:Hg19::chr4:154265825..154265875,+#_956b476bdb576b8b46ba0e905d63cb06p1@MND1
7.67e-59FFCP PHASE1:Hg19::chr17:48450575..48450618,+#_d2249659e41ae7160acacd35d933fff0p1@EME1
7.67e-59FFCP PHASE2:Hg19::chr17:48450575..48450618,+#_d2249659e41ae7160acacd35d933fff0p1@EME1
1.11e-58FFCP PHASE1:Hg19::chr15:69706740..69706754,+#_47359bd07ca880b84506d9d2fd3d39edp2@KIF23
1.11e-58FFCP PHASE2:Hg19::chr15:69706740..69706754,+#_47359bd07ca880b84506d9d2fd3d39edp2@KIF23
2.3e-58FFCP PHASE2:Hg19::chr6:20402102..20402152,+#_7bf6948701bd615c0268be70b9e253a6p1@E2F3
2.3e-58FFCP PHASE1:Hg19::chr6:20402102..20402152,+#_7bf6948701bd615c0268be70b9e253a6p1@E2F3
4.85e-58FFCP PHASE2:Hg19::chr10:62538228..62538244,+#_97190b1e8fdcc55f8a1018aca2af1780p1@CDK1
4.85e-58FFCP PHASE1:Hg19::chr10:62538228..62538244,+#_97190b1e8fdcc55f8a1018aca2af1780p1@CDK1
5.95e-58FFCP PHASE2:Hg19::chr2:113522177..113522228,-#_46abf9e813609327fe05eed4f71fd17bp1@CKAP2L
5.95e-58FFCP PHASE1:Hg19::chr2:113522177..113522228,-#_46abf9e813609327fe05eed4f71fd17bp1@CKAP2L
7.72e-58FFCP PHASE1:Hg19::chr17:57233087..57233146,+#_ae213e1e27bfbbc6ef55b9bedf09e998p1@PRR11
7.72e-58FFCP PHASE2:Hg19::chr17:57233087..57233146,+#_ae213e1e27bfbbc6ef55b9bedf09e998p1@PRR11
9.18e-58FFCP PHASE1:Hg19::chr17:38552615..38552637,-#_29b6fdb9d877203762ac6ea3bd20c130p@chr17:38552615..38552637, -
9.18e-58FFCP PHASE2:Hg19::chr17:38552615..38552637,-#_29b6fdb9d877203762ac6ea3bd20c130p@chr17:38552615..38552637, -
9.86e-58FFCP PHASE1:Hg19::chr3:186524234..186524303,-#_e2294347da69e94f736bbd5a84cebe4ap1@RFC4
9.86e-58FFCP PHASE2:Hg19::chr3:186524234..186524303,-#_e2294347da69e94f736bbd5a84cebe4ap1@RFC4