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Coexpression cluster:C83

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Full id: C83_choriocarcinoma_pancreatic_placenta_chorionic_HES3GFP_testicular_amniotic



Phase1 CAGE Peaks

Hg19::chr10:123748959..123748979,+p31@TACC2
Hg19::chr10:133609735..133609740,-p@chr10:133609735..133609740
-
Hg19::chr10:48320905..48320918,+p@chr10:48320905..48320918
+
Hg19::chr10:5535686..5535697,-p@chr10:5535686..5535697
-
Hg19::chr10:5535709..5535712,-p@chr10:5535709..5535712
-
Hg19::chr10:5535718..5535735,-p@chr10:5535718..5535735
-
Hg19::chr10:5535798..5535807,-p@chr10:5535798..5535807
-
Hg19::chr10:5593064..5593072,-p@chr10:5593064..5593072
-
Hg19::chr10:5593091..5593100,-p@chr10:5593091..5593100
-
Hg19::chr10:5593123..5593133,-p@chr10:5593123..5593133
-
Hg19::chr10:98045196..98045205,-p@chr10:98045196..98045205
-
Hg19::chr11:10066129..10066131,-p21@SBF2
Hg19::chr11:10066159..10066186,-p3@SBF2
Hg19::chr11:123067131..123067134,-p@chr11:123067131..123067134
-
Hg19::chr11:35845720..35845725,+p@chr11:35845720..35845725
+
Hg19::chr11:35845729..35845739,+p@chr11:35845729..35845739
+
Hg19::chr11:35845764..35845771,+p@chr11:35845764..35845771
+
Hg19::chr11:61766893..61766898,+p@chr11:61766893..61766898
+
Hg19::chr11:76883803..76883839,+p2@MYO7A
Hg19::chr12:10063622..10063630,-p@chr12:10063622..10063630
-
Hg19::chr12:104069561..104069571,+p@chr12:104069561..104069571
+
Hg19::chr12:32197097..32197105,-p@chr12:32197097..32197105
-
Hg19::chr12:51811923..51811932,+p@chr12:51811923..51811932
+
Hg19::chr12:56349615..56349624,-p@chr12:56349615..56349624
-
Hg19::chr12:56349626..56349632,-p@chr12:56349626..56349632
-
Hg19::chr12:56349633..56349678,-p@chr12:56349633..56349678
-
Hg19::chr12:56349969..56349984,-p11@PMEL
Hg19::chr12:7308463..7308481,+p2@CLSTN3
Hg19::chr13:113559520..113559524,-p@chr13:113559520..113559524
-
Hg19::chr13:53444171..53444197,+p@chr13:53444171..53444197
+
Hg19::chr14:62137439..62137449,+p@chr14:62137439..62137449
+
Hg19::chr14:62137566..62137579,+p@chr14:62137566..62137579
+
Hg19::chr14:64228555..64228592,+p1@ENST00000554348
Hg19::chr14:70278563..70278570,+p@chr14:70278563..70278570
+
Hg19::chr14:73514888..73514898,-p@chr14:73514888..73514898
-
Hg19::chr14:93094282..93094285,-p@chr14:93094282..93094285
-
Hg19::chr15:63084847..63084861,+p@chr15:63084847..63084861
+
Hg19::chr15:63187978..63187988,+p3@ENST00000557900
Hg19::chr15:63187989..63188004,+p1@ENST00000557900
Hg19::chr15:63188009..63188017,+p2@ENST00000557900
Hg19::chr15:72452671..72452675,-p@chr15:72452671..72452675
-
Hg19::chr15:72462584..72462595,-p@chr15:72462584..72462595
-
Hg19::chr15:72462618..72462629,-p@chr15:72462618..72462629
-
Hg19::chr15:72462661..72462678,-p@chr15:72462661..72462678
-
Hg19::chr15:72462685..72462696,-p@chr15:72462685..72462696
-
Hg19::chr15:72462705..72462734,-p@chr15:72462705..72462734
-
Hg19::chr15:72462757..72462779,-p@chr15:72462757..72462779
-
Hg19::chr15:74657431..74657449,-p@chr15:74657431..74657449
-
Hg19::chr16:24895199..24895203,+p@chr16:24895199..24895203
+
Hg19::chr16:30387364..30387401,+p@chr16:30387364..30387401
+
Hg19::chr16:53447180..53447184,+p@chr16:53447180..53447184
+
Hg19::chr16:58271066..58271067,+p@chr16:58271066..58271067
+
Hg19::chr16:66411508..66411515,+p@chr16:66411508..66411515
+
Hg19::chr16:66413154..66413184,+p4@CDH5
Hg19::chr16:66413188..66413195,+p9@CDH5
Hg19::chr16:66413204..66413234,+p5@CDH5
Hg19::chr16:66413237..66413255,+p7@CDH5
Hg19::chr16:85524820..85524831,+p@chr16:85524820..85524831
+
Hg19::chr16:87982836..87982869,+p@chr16:87982836..87982869
+
Hg19::chr17:26578258..26578273,-p@chr17:26578258..26578273
-
Hg19::chr17:37202362..37202365,+p@chr17:37202362..37202365
+
Hg19::chr17:37202370..37202372,+p@chr17:37202370..37202372
+
Hg19::chr17:37202373..37202417,+p@chr17:37202373..37202417
+
Hg19::chr17:37202443..37202454,+p@chr17:37202443..37202454
+
Hg19::chr17:37202489..37202501,+p@chr17:37202489..37202501
+
Hg19::chr17:61982110..61982150,-p@chr17:61982110..61982150
-
Hg19::chr17:63456009..63456037,-p@chr17:63456009..63456037
-
Hg19::chr17:8620694..8620698,-p@chr17:8620694..8620698
-
Hg19::chr17:8620771..8620777,-p@chr17:8620771..8620777
-
Hg19::chr18:18822185..18822213,+p1@GREB1L
Hg19::chr18:18822216..18822246,+p2@GREB1L
Hg19::chr18:44448607..44448612,+p@chr18:44448607..44448612
+
Hg19::chr18:44448806..44448810,+p@chr18:44448806..44448810
+
Hg19::chr18:5410605..5410661,-p@chr18:5410605..5410661
-
Hg19::chr19:10311868..10311875,-p@chr19:10311868..10311875
-
Hg19::chr19:10311880..10311889,-p@chr19:10311880..10311889
-
Hg19::chr19:10311892..10311903,-p@chr19:10311892..10311903
-
Hg19::chr19:10311913..10311922,-p@chr19:10311913..10311922
-
Hg19::chr19:17985223..17985229,+p@chr19:17985223..17985229
+
Hg19::chr19:17985256..17985266,+p@chr19:17985256..17985266
+
Hg19::chr19:46714539..46714548,-p@chr19:46714539..46714548
-
Hg19::chr19:46743663..46743672,+p@chr19:46743663..46743672
+
Hg19::chr19:51255914..51255949,+p@chr19:51255914..51255949
+
Hg19::chr19:51267056..51267062,+p@chr19:51267056..51267062
+
Hg19::chr19:51267103..51267109,+p@chr19:51267103..51267109
+
Hg19::chr19:54151293..54151308,+p@chr19:54151293..54151308
+
Hg19::chr19:54153488..54153491,+p@chr19:54153488..54153491
+
Hg19::chr19:54163435..54163438,+p@chr19:54163435..54163438
+
Hg19::chr19:54197719..54197722,+p1@MIR526B
Hg19::chr19:54274746..54274752,+p@chr19:54274746..54274752
+
Hg19::chr19:55476646..55476685,+p2@NLRP2
Hg19::chr19:55486510..55486514,+p@chr19:55486510..55486514
+
Hg19::chr19:7844935..7844942,+p@chr19:7844935..7844942
+
Hg19::chr19:7872639..7872658,+p@chr19:7872639..7872658
+
Hg19::chr19:9150602..9150619,+p@chr19:9150602..9150619
+
Hg19::chr1:113392146..113392158,+p6@ENST00000456651
Hg19::chr1:167832811..167832845,+p@chr1:167832811..167832845
+
Hg19::chr1:167832890..167832900,+p@chr1:167832890..167832900
+
Hg19::chr1:173606833..173606850,+p1@AK303487
Hg19::chr1:173626783..173626786,+p@chr1:173626783..173626786
+
Hg19::chr1:201508829..201508877,+p@chr1:201508829..201508877
+
Hg19::chr1:204283395..204283415,-p@chr1:204283395..204283415
-
Hg19::chr1:204288638..204288673,-p@chr1:204288638..204288673
-
Hg19::chr1:229230644..229230665,-p1@ENST00000433734
Hg19::chr1:235833012..235833038,+p@chr1:235833012..235833038
+
Hg19::chr1:235833537..235833548,+p@chr1:235833537..235833548
+
Hg19::chr1:235833608..235833627,+p@chr1:235833608..235833627
+
Hg19::chr1:246960990..246961035,-p@chr1:246960990..246961035
-
Hg19::chr1:26595752..26595776,+p5@CEP85
Hg19::chr20:32317248..32317251,+p@chr20:32317248..32317251
+
Hg19::chr20:32317395..32317398,+p@chr20:32317395..32317398
+
Hg19::chr20:40398479..40398484,+p@chr20:40398479..40398484
+
Hg19::chr20:4990931..4990943,-p6@SLC23A2
Hg19::chr20:4990952..4990966,-p4@SLC23A2
Hg19::chr21:44352326..44352341,+p@chr21:44352326..44352341
+
Hg19::chr22:24551128..24551148,+p@chr22:24551128..24551148
+
Hg19::chr22:26106696..26106736,+p@chr22:26106696..26106736
+
Hg19::chr22:39861099..39861102,+p@chr22:39861099..39861102
+
Hg19::chr22:46847254..46847263,-p@chr22:46847254..46847263
-
Hg19::chr2:10091881..10091890,+p5@GRHL1
Hg19::chr2:10092022..10092062,+p@chr2:10092022..10092062
+
Hg19::chr2:106468296..106468312,+p3@NCK2
Hg19::chr2:128794706..128794716,+p@chr2:128794706..128794716
+
Hg19::chr2:174738938..174738953,-p@chr2:174738938..174738953
-
Hg19::chr2:174891341..174891354,-p@chr2:174891341..174891354
-
Hg19::chr2:238859791..238859796,-p@chr2:238859791..238859796
-
Hg19::chr2:238871320..238871337,-p@chr2:238871320..238871337
-
Hg19::chr2:27434468..27434481,-p14@SLC5A6
Hg19::chr2:74210915..74210939,+p@chr2:74210915..74210939
+
Hg19::chr2:74210964..74210982,+p@chr2:74210964..74210982
+
Hg19::chr2:75436235..75436244,+p@chr2:75436235..75436244
+
Hg19::chr2:75436260..75436266,+p@chr2:75436260..75436266
+
Hg19::chr2:86491283..86491292,-p@chr2:86491283..86491292
-
Hg19::chr2:86491324..86491329,-p@chr2:86491324..86491329
-
Hg19::chr2:86491350..86491362,-p@chr2:86491350..86491362
-
Hg19::chr2:86491368..86491379,-p@chr2:86491368..86491379
-
Hg19::chr2:86491387..86491391,-p@chr2:86491387..86491391
-
Hg19::chr2:86491395..86491399,-p@chr2:86491395..86491399
-
Hg19::chr2:99485829..99485855,-p3@C2orf55
Hg19::chr2:9954843..9954863,-p@chr2:9954843..9954863
-
Hg19::chr2:9956075..9956086,-p@chr2:9956075..9956086
-
Hg19::chr3:127987497..127987505,+p@chr3:127987497..127987505
+
Hg19::chr3:138103078..138103094,+p@chr3:138103078..138103094
+
Hg19::chr3:195869379..195869411,+p2@LOC401109
Hg19::chr3:32859762..32859795,+p2@TRIM71
Hg19::chr3:41143626..41143645,-p@chr3:41143626..41143645
-
Hg19::chr3:48514524..48514576,-p2@SHISA5
Hg19::chr4:111397216..111397250,+p8@ENPEP
Hg19::chr4:148637470..148637497,+p@chr4:148637470..148637497
+
Hg19::chr4:188963120..188963125,+p@chr4:188963120..188963125
+
Hg19::chr4:688547..688550,+p@chr4:688547..688550
+
Hg19::chr4:8562207..8562219,+p@chr4:8562207..8562219
+
Hg19::chr4:8574452..8574462,+p@chr4:8574452..8574462
+
Hg19::chr4:99942777..99942781,-p@chr4:99942777..99942781
-
Hg19::chr5:122108231..122108249,-p@chr5:122108231..122108249
-
Hg19::chr5:148650940..148650958,+p3@AFAP1L1
Hg19::chr5:149493034..149493043,-p11@CSF1R
Hg19::chr5:154258307..154258327,+p@chr5:154258307..154258327
+
Hg19::chr5:1551802..1551839,-p1@ENST00000503113
Hg19::chr5:174156632..174156640,+p@chr5:174156632..174156640
+
Hg19::chr5:414689..414704,+p@chr5:414689..414704
+
Hg19::chr5:55008072..55008098,-p3@SLC38A9
Hg19::chr5:78843442..78843462,-p@chr5:78843442..78843462
-
Hg19::chr5:80255117..80255127,+p@chr5:80255117..80255127
+
Hg19::chr5:80255208..80255217,+p@chr5:80255208..80255217
+
Hg19::chr5:80255223..80255232,+p@chr5:80255223..80255232
+
Hg19::chr5:80255251..80255268,+p@chr5:80255251..80255268
+
Hg19::chr6:105384868..105384889,+p@chr6:105384868..105384889
+
Hg19::chr6:105384893..105384944,+p@chr6:105384893..105384944
+
Hg19::chr6:118895222..118895233,-p9@CEP85L
Hg19::chr6:118895247..118895267,-p4@CEP85L
Hg19::chr6:118895275..118895291,-p8@CEP85L
Hg19::chr6:118895550..118895560,+p@chr6:118895550..118895560
+
Hg19::chr6:138709576..138709607,-p@chr6:138709576..138709607
-
Hg19::chr6:21740324..21740340,+p@chr6:21740324..21740340
+
Hg19::chr6:35531197..35531202,-p@chr6:35531197..35531202
-
Hg19::chr6:35534724..35534731,-p@chr6:35534724..35534731
-
Hg19::chr6:3777288..3777300,-p@chr6:3777288..3777300
-
Hg19::chr6:3777451..3777464,-p@chr6:3777451..3777464
-
Hg19::chr6:3789029..3789041,-p@chr6:3789029..3789041
-
Hg19::chr6:3789070..3789079,-p@chr6:3789070..3789079
-
Hg19::chr6:3789091..3789100,-p@chr6:3789091..3789100
-
Hg19::chr6:3789102..3789116,-p@chr6:3789102..3789116
-
Hg19::chr6:41703952..41703994,-p4@TFEB
Hg19::chr6:42399770..42399783,-p@chr6:42399770..42399783
-
Hg19::chr6:56258897..56258905,-p9@COL21A1
Hg19::chr6:56258920..56258931,-p6@COL21A1
Hg19::chr7:108168580..108168628,-p5@PNPLA8
Hg19::chr7:134249850..134249864,+p2@AKR1B15
Hg19::chr7:136953060..136953106,-p@chr7:136953060..136953106
-
Hg19::chr7:136953121..136953150,-p@chr7:136953121..136953150
-
Hg19::chr7:136953324..136953328,-p@chr7:136953324..136953328
-
Hg19::chr7:151124094..151124119,+p@chr7:151124094..151124119
+
Hg19::chr7:24834794..24834805,-p@chr7:24834794..24834805
-
Hg19::chr7:48153941..48153973,-p@chr7:48153941..48153973
-
Hg19::chr7:73213866..73213877,+p2@CLDN4
Hg19::chr7:73219088..73219092,+p@chr7:73219088..73219092
+
Hg19::chr7:73227794..73227798,+p@chr7:73227794..73227798
+
Hg19::chr7:75585701..75585723,+p@chr7:75585701..75585723
+
Hg19::chr8:144120622..144120629,+p7@C8orf31
Hg19::chr8:144120630..144120642,+p3@C8orf31
Hg19::chr8:38831662..38831673,+p4@HTRA4
Hg19::chr9:127358120..127358170,-p3@NR6A1
Hg19::chr9:138536853..138536859,+p@chr9:138536853..138536859
+
Hg19::chr9:139873342..139873374,+p6@PTGDS
Hg19::chr9:139893057..139893072,-p@chr9:139893057..139893072
-
Hg19::chr9:140011704..140011710,+p@chr9:140011704..140011710
+
Hg19::chr9:27421712..27421738,-p@chr9:27421712..27421738
-
Hg19::chr9:90659348..90659354,-p@chr9:90659348..90659354
-
Hg19::chr9:90959073..90959080,-p@chr9:90959073..90959080
-
Hg19::chrX:135614293..135614318,+p2@VGLL1
Hg19::chrX:135614338..135614348,+p4@VGLL1
Hg19::chrX:135614355..135614362,+p5@VGLL1
Hg19::chrX:135614364..135614387,+p1@VGLL1
Hg19::chrX:135614405..135614416,+p3@VGLL1
Hg19::chrX:135614605..135614629,+p@chrX:135614605..135614629
+
Hg19::chrX:135630768..135630780,+p@chrX:135630768..135630780
+
Hg19::chrX:135630916..135630937,+p@chrX:135630916..135630937
+
Hg19::chrX:135630943..135630952,+p@chrX:135630943..135630952
+
Hg19::chrX:135630960..135630983,+p@chrX:135630960..135630983
+
Hg19::chrX:135631090..135631102,+p@chrX:135631090..135631102
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008523sodium-dependent multivitamin transmembrane transporter activity0.000169737728278866
GO:0032501multicellular organismal process0.0274409360695467
GO:0022410circadian sleep/wake cycle process0.0274409360695467
GO:0045187regulation of circadian sleep/wake cycle, sleep0.0274409360695467
GO:0042749regulation of circadian sleep/wake cycle0.0274409360695467
GO:0004230glutamyl aminopeptidase activity0.0274409360695467
GO:0050802circadian sleep/wake cycle, sleep0.0274409360695467
GO:0015993molecular hydrogen transport0.0274409360695467
GO:0005774vacuolar membrane0.0274409360695467
GO:0044437vacuolar part0.0274409360695467
GO:0005624membrane fraction0.0274409360695467
GO:0008283cell proliferation0.0274409360695467
GO:0005515protein binding0.0274409360695467
GO:0005011macrophage colony stimulating factor receptor activity0.0274409360695467
GO:0004667prostaglandin-D synthase activity0.0274409360695467
GO:0042745circadian sleep/wake cycle0.0274409360695467
GO:0032090Pyrin domain binding0.0274409360695467
GO:0001917photoreceptor inner segment0.0274409360695467
GO:0005887integral to plasma membrane0.0274409360695467
GO:0016337cell-cell adhesion0.0274409360695467
GO:0031226intrinsic to plasma membrane0.0274409360695467
GO:0015370solute:sodium symporter activity0.0274409360695467
GO:0042802identical protein binding0.0274409360695467
GO:0046983protein dimerization activity0.0274409360695467
GO:0031402sodium ion binding0.0274409360695467
GO:0048512circadian behavior0.0274409360695467
GO:0019852L-ascorbic acid metabolic process0.0274409360695467
GO:0042752regulation of circadian rhythm0.0274409360695467
GO:0047499calcium-independent phospholipase A2 activity0.0274409360695467
GO:0007622rhythmic behavior0.0274409360695467
GO:0000267cell fraction0.0326975459035358
GO:0015294solute:cation symporter activity0.0326975459035358
GO:0015851nucleobase transport0.0332514616290853
GO:0044459plasma membrane part0.0335142285710582
GO:0022610biological adhesion0.0351589473676664
GO:0007155cell adhesion0.0351589473676664
GO:0030431sleep0.0351589473676664
GO:0015205nucleobase transmembrane transporter activity0.0351589473676664
GO:0030838positive regulation of actin filament polymerization0.0351589473676664
GO:0001750photoreceptor outer segment0.0476496838455442
GO:0042803protein homodimerization activity0.0476496838455442
GO:0050957equilibrioception0.0476496838455442
GO:0050706regulation of interleukin-1 beta secretion0.0476496838455442
GO:0008093cytoskeletal adaptor activity0.0476496838455442
GO:0050718positive regulation of interleukin-1 beta secretion0.0476496838455442
GO:0007176regulation of epidermal growth factor receptor activity0.0476496838455442
GO:0006814sodium ion transport0.0483354787294576
GO:0050716positive regulation of interleukin-1 secretion0.0483354787294576
GO:0004622lysophospholipase activity0.0483354787294576
GO:0031513nonmotile primary cilium0.0483354787294576
GO:0050704regulation of interleukin-1 secretion0.0483354787294576



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
germ line cell4.35e-377
germ cell4.35e-377
epithelial cell of pancreas1.82e-084
Uber Anatomy
Ontology termp-valuen
placenta2.26e-084
allantois2.26e-084


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
GATA3#2625202.464843109249410.0002161412948320040.00247680279690144
SETDB1#9869254.561088934164084.02130008771521e-103.96208075340461e-08
TRIM28#10155252.103000570731050.0003962839322763390.00387414561480937



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data