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Coexpression cluster:C1052

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Full id: C1052_signet_colon_mucinous_papillotubular_adenocarcinoma_gall_thyroid



Phase1 CAGE Peaks

  Short description
Hg19::chr17:55185128..55185169,+ p@chr17:55185128..55185169
+
Hg19::chr19:10142131..10142138,- p@chr19:10142131..10142138
-
Hg19::chr7:960463..960466,- p25@ADAP1
Hg19::chr7:960507..960519,- p9@ADAP1
Hg19::chr7:960521..960533,- p15@ADAP1
Hg19::chr9:140189285..140189325,+ +
p@chr9:140189285..140189325
Hg19::chr9:85678229..85678237,+ p@chr9:85678229..85678237
+
Hg19::chr9:85678281..85678294,+ +
p@chr9:85678281..85678294


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data
disease_data


Cell Type
Ontology termp-valuen
epithelial cell of gall bladder1.86e-092
epithelial cell of stomach5.80e-073
pneumocyte7.70e-073
Uber Anatomy
Ontology termp-valuen
biliary system1.43e-299
biliary tree1.43e-299
biliary bud1.43e-299
gallbladder5.76e-233
gall bladder primordium5.76e-233
hepatopancreatic ampulla5.26e-181
extrahepatic bile duct5.26e-181
common bile duct5.26e-181
duodenal papilla5.26e-181
maxillary sinus1.03e-171
paranasal sinus1.03e-171
small intestine4.11e-144
bile duct5.68e-126
digestive system duct5.68e-126
epithelium of foregut-midgut junction6.75e-1125
anatomical boundary6.75e-1125
hepatobiliary system6.75e-1125
foregut-midgut junction6.75e-1125
septum transversum6.75e-1125
gastrointestinal system1.60e-1025
bronchoalveolar duct junction1.22e-092
alveolar duct1.22e-092
bronchiole1.22e-092
intestine7.65e-0917
duct1.89e-0819
duodenum7.28e-072
pulmonary alveolus epithelium7.70e-073
alveolus7.70e-073
pulmonary lobule7.70e-073
lobule7.70e-073
alveolus of lung7.70e-073
alveolar system7.70e-073
pulmonary acinus7.70e-073
alveolar sac7.70e-073
alveolar wall7.70e-073


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.140538
MA0004.12.01344
MA0006.10.300178
MA0007.10.437331
MA0009.10.918715
MA0014.10.275152
MA0017.11.60885
MA0019.10.602411
MA0024.11.90464
MA0025.11.05265
MA0027.12.5321
MA0028.10.315574
MA0029.10.832916
MA0030.10.821423
MA0031.10.756713
MA0038.10.557409
MA0040.10.838784
MA0041.10.474018
MA0042.10.442535
MA0043.10.919032
MA0046.10.90778
MA0048.12.19172
MA0050.10.443405
MA0051.10.553205
MA0052.10.842664
MA0055.10.028436
MA0056.10
MA0057.10.0912556
MA0058.10.950944
MA0059.10.361075
MA0060.10.190336
MA0061.10.165998
MA0063.10
MA0066.10.557833
MA0067.11.23721
MA0068.10.133123
MA0069.10.903908
MA0070.10.892666
MA0071.10.518907
MA0072.10.888148
MA0073.10.0719479
MA0074.10.552456
MA0076.10.377799
MA0077.10.880402
MA0078.10.652193
MA0081.10.361233
MA0083.10.926258
MA0084.11.42483
MA0087.10.885691
MA0088.10.199853
MA0089.10
MA0090.10.391903
MA0091.10.458301
MA0092.10.421159
MA0093.13.13688
MA0095.10
MA0098.10
MA0100.10.571227
MA0101.10.30624
MA0103.12.20626
MA0105.10.279181
MA0106.10.59853
MA0107.10.236528
MA0108.20.753643
MA0109.10
MA0111.10.405141
MA0113.10.614917
MA0114.13.50771
MA0115.11.1606
MA0116.10.239768
MA0117.10.956472
MA0119.10.913661
MA0122.10.982472
MA0124.11.11898
MA0125.11.0347
MA0130.10
MA0131.10.670358
MA0132.10
MA0133.10
MA0135.10.949204
MA0136.10.564434
MA0139.10.155155
MA0140.10.516266
MA0141.10.944441
MA0142.10.724856
MA0143.10.615094
MA0144.10.218541
MA0145.11.25866
MA0146.10.934908
MA0147.10.243042
MA0148.10.480298
MA0149.10.506665
MA0062.21.50503
MA0035.20.515566
MA0039.20.164269
MA0138.20.653421
MA0002.21.61227
MA0137.20.321796
MA0104.20.55506
MA0047.20.586412
MA0112.21.21228
MA0065.21.27835
MA0150.10.386144
MA0151.10
MA0152.11.29801
MA0153.11.01778
MA0154.10.577214
MA0155.10.764865
MA0156.10.323987
MA0157.10.697424
MA0158.10
MA0159.10.243637
MA0160.10.495355
MA0161.10
MA0162.10.0752715
MA0163.10.0517199
MA0164.10.627336
MA0080.20.818924
MA0018.20.599912
MA0099.21.29876
MA0079.20.000390427
MA0102.21.46209
MA0258.11.13653
MA0259.10.699589
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.