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{{Coexpression_clusters
{
|coexpression_dpi_cluster_scores_median=0,0

Latest revision as of 10:30, 17 September 2013


Full id: C97_small_smallcell_gastrointestinal_argyrophil_putamen_duodenum_brain



Phase1 CAGE Peaks

Hg19::chr10:113748431..113748441,-p@chr10:113748431..113748441
-
Hg19::chr10:120355149..120355165,-p1@PRLHR
Hg19::chr11:129305906..129305908,+p7@BARX2
Hg19::chr11:1643561..1643566,+p@chr11:1643561..1643566
+
Hg19::chr11:18034532..18034548,-p4@SERGEF
Hg19::chr11:26618692..26618727,-p@chr11:26618692..26618727
-
Hg19::chr11:26618988..26619017,-p@chr11:26618988..26619017
-
Hg19::chr11:42912594..42912599,-p@chr11:42912594..42912599
-
Hg19::chr11:42912793..42912802,-p@chr11:42912793..42912802
-
Hg19::chr11:4665150..4665166,+p2@OR51E1
Hg19::chr11:4665183..4665193,+p3@OR51E1
Hg19::chr11:4665195..4665219,+p1@OR51E1
Hg19::chr11:4726012..4726018,+p1@MMP26
Hg19::chr11:4726112..4726125,+p2@MMP26
Hg19::chr11:4807754..4807756,+p1@OR51N1P
Hg19::chr11:5445690..5445716,+p@chr11:5445690..5445716
+
Hg19::chr11:67402354..67402359,-p@chr11:67402354..67402359
-
Hg19::chr11:67402368..67402378,-p@chr11:67402368..67402378
-
Hg19::chr11:78177190..78177210,-p@chr11:78177190..78177210
-
Hg19::chr12:127545156..127545162,+p@chr12:127545156..127545162
+
Hg19::chr12:132556644..132556656,+p@chr12:132556644..132556656
+
Hg19::chr12:51116443..51116452,+p@chr12:51116443..51116452
+
Hg19::chr12:53686428..53686432,+p@chr12:53686428..53686432
+
Hg19::chr12:53686472..53686482,+p@chr12:53686472..53686482
+
Hg19::chr12:58158560..58158567,-p@chr12:58158560..58158567
-
Hg19::chr12:76206813..76206837,-p@chr12:76206813..76206837
-
Hg19::chr13:25269076..25269105,-p@chr13:25269076..25269105
-
Hg19::chr13:25269257..25269262,+p@chr13:25269257..25269262
+
Hg19::chr14:36966895..36966899,-p@chr14:36966895..36966899
-
Hg19::chr14:57127818..57127825,+p@chr14:57127818..57127825
+
Hg19::chr14:57127856..57127863,+p@chr14:57127856..57127863
+
Hg19::chr15:62007373..62007374,-p2@ENST00000559590
Hg19::chr15:62007379..62007390,-p1@ENST00000559590
Hg19::chr16:11846874..11846885,-p14@ZC3H7A
Hg19::chr16:19396252..19396261,+p@chr16:19396252..19396261
+
Hg19::chr16:30015874..30015893,+p@chr16:30015874..30015893
+
Hg19::chr16:7354032..7354043,+p@chr16:7354032..7354043
+
Hg19::chr16:7354527..7354551,-p@chr16:7354527..7354551
-
Hg19::chr16:7354636..7354645,-p@chr16:7354636..7354645
-
Hg19::chr16:7354657..7354690,-p@chr16:7354657..7354690
-
Hg19::chr16:7428243..7428259,+p@chr16:7428243..7428259
+
Hg19::chr16:83649377..83649388,+p@chr16:83649377..83649388
+
Hg19::chr16:83649482..83649491,+p@chr16:83649482..83649491
+
Hg19::chr16:8524660..8524680,-p@chr16:8524660..8524680
-
Hg19::chr17:27308382..27308398,+p@chr17:27308382..27308398
+
Hg19::chr17:27333028..27333089,-p1@SEZ6
Hg19::chr17:27333187..27333207,-p13@SEZ6
Hg19::chr17:27333311..27333318,-p21@SEZ6
Hg19::chr17:39140393..39140399,-p3@KRT40
Hg19::chr17:39140411..39140419,-p5@KRT40
Hg19::chr17:39140424..39140431,-p4@KRT40
Hg19::chr17:39140549..39140579,-p1@KRT40
Hg19::chr17:43749913..43749923,+p@chr17:43749913..43749923
+
Hg19::chr17:78560489..78560497,+p@chr17:78560489..78560497
+
Hg19::chr18:31185530..31185578,+p@chr18:31185530..31185578
+
Hg19::chr18:33311016..33311032,-p@chr18:33311016..33311032
-
Hg19::chr18:35250432..35250444,+p@chr18:35250432..35250444
+
Hg19::chr18:73967160..73967162,-p@chr18:73967160..73967162
-
Hg19::chr18:73967189..73967200,-p@chr18:73967189..73967200
-
Hg19::chr18:73967203..73967220,-p@chr18:73967203..73967220
-
Hg19::chr18:74671119..74671124,+p@chr18:74671119..74671124
+
Hg19::chr18:8331753..8331793,+p@chr18:8331753..8331793
+
Hg19::chr19:46520090..46520102,-p@chr19:46520090..46520102
-
Hg19::chr19:46531064..46531073,+p@chr19:46531064..46531073
+
Hg19::chr19:46531131..46531136,+p@chr19:46531131..46531136
+
Hg19::chr19:46763326..46763349,+p@chr19:46763326..46763349
+
Hg19::chr19:46763651..46763662,+p@chr19:46763651..46763662
+
Hg19::chr19:46763803..46763808,-p@chr19:46763803..46763808
-
Hg19::chr19:51586029..51586039,-p2@KLK14
Hg19::chr19:56681707..56681748,-p@chr19:56681707..56681748
-
Hg19::chr19:9811101..9811112,-p3@ZNF812
Hg19::chr19:9811125..9811144,-p2@ZNF812
Hg19::chr1:11908185..11908202,-p6@NPPA
Hg19::chr1:11908227..11908236,-p8@NPPA
Hg19::chr1:15904346..15904358,-p@chr1:15904346..15904358
-
Hg19::chr1:194327155..194327162,-p@chr1:194327155..194327162
-
Hg19::chr1:223276523..223276530,-p@chr1:223276523..223276530
-
Hg19::chr1:223919301..223919303,+p@chr1:223919301..223919303
+
Hg19::chr1:225650299..225650317,-p@chr1:225650299..225650317
-
Hg19::chr1:226071797..226071822,-p@chr1:226071797..226071822
-
Hg19::chr1:28384655..28384680,-p7@EYA3
Hg19::chr1:6534668..6534704,-p@chr1:6534668..6534704
-
Hg19::chr1:67021937..67021942,+p@chr1:67021937..67021942
+
Hg19::chr1:79654075..79654086,-p@chr1:79654075..79654086
-
Hg19::chr21:29774393..29774422,-p@chr21:29774393..29774422
-
Hg19::chr21:29774431..29774441,-p@chr21:29774431..29774441
-
Hg19::chr21:39465959..39465961,+p@chr21:39465959..39465961
+
Hg19::chr21:43917055..43917058,-p@chr21:43917055..43917058
-
Hg19::chr22:38539185..38539224,-p9@PLA2G6
Hg19::chr22:38539262..38539297,-p11@PLA2G6
Hg19::chr2:120488121..120488144,-p@chr2:120488121..120488144
-
Hg19::chr2:148259693..148259714,-p@chr2:148259693..148259714
-
Hg19::chr2:170573896..170573900,-p@chr2:170573896..170573900
-
Hg19::chr2:176962389..176962394,-p@chr2:176962389..176962394
-
Hg19::chr2:21444025..21444055,+p1@ENST00000435237
Hg19::chr2:234862280..234862298,+p9@TRPM8
Hg19::chr2:234862313..234862320,+p15@TRPM8
Hg19::chr2:234862392..234862408,+p5@TRPM8
Hg19::chr2:234862409..234862414,+p14@TRPM8
Hg19::chr2:234862417..234862434,+p6@TRPM8
Hg19::chr2:234862436..234862439,+p16@TRPM8
Hg19::chr2:235841327..235841336,+p@chr2:235841327..235841336
+
Hg19::chr2:238385078..238385087,-p@chr2:238385078..238385087
-
Hg19::chr2:241625343..241625356,+p4@ENST00000407635
Hg19::chr2:241625364..241625374,+p5@ENST00000407635
Hg19::chr2:241625384..241625391,+p10@ENST00000407635
Hg19::chr2:241625475..241625482,+p8@ENST00000407635
Hg19::chr2:241625540..241625541,+p14@ENST00000407635
Hg19::chr2:241625548..241625569,+p1@ENST00000407635
Hg19::chr2:241625621..241625629,+p2@ENST00000407635
Hg19::chr2:241625689..241625696,+p7@ENST00000407635
Hg19::chr2:241625703..241625706,+p12@ENST00000407635
Hg19::chr2:28785672..28785682,+p@chr2:28785672..28785682
+
Hg19::chr2:28785693..28785704,+p@chr2:28785693..28785704
+
Hg19::chr2:28785707..28785729,+p@chr2:28785707..28785729
+
Hg19::chr2:3131535..3131547,-p@chr2:3131535..3131547
-
Hg19::chr3:102635374..102635381,-p@chr3:102635374..102635381
-
Hg19::chr3:102635409..102635414,-p@chr3:102635409..102635414
-
Hg19::chr3:102635473..102635480,-p@chr3:102635473..102635480
-
Hg19::chr3:142338164..142338210,+p@chr3:142338164..142338210
+
Hg19::chr3:145094664..145094665,+p@chr3:145094664..145094665
+
Hg19::chr4:10734349..10734351,-p@chr4:10734349..10734351
-
Hg19::chr4:185018490..185018512,-p@chr4:185018490..185018512
-
Hg19::chr4:185426203..185426209,-p@chr4:185426203..185426209
-
Hg19::chr4:23882555..23882575,-p4@HQ695733
Hg19::chr4:3310694..3310716,-p@chr4:3310694..3310716
-
Hg19::chr4:3344392..3344399,+p@chr4:3344392..3344399
+
Hg19::chr4:3344412..3344423,+p@chr4:3344412..3344423
+
Hg19::chr4:3344434..3344441,+p@chr4:3344434..3344441
+
Hg19::chr4:3344577..3344588,+p@chr4:3344577..3344588
+
Hg19::chr5:102141951..102141981,+p@chr5:102141951..102141981
+
Hg19::chr5:102143544..102143550,+p42@PAM
Hg19::chr5:102143894..102143910,+p6@PAM
Hg19::chr5:1445539..1445558,-p1@SLC6A3
Hg19::chr5:30198094..30198099,+p@chr5:30198094..30198099
+
Hg19::chr5:79097476..79097484,+p@chr5:79097476..79097484
+
Hg19::chr6:104852320..104852330,-p@chr6:104852320..104852330
-
Hg19::chr6:154707166..154707170,-p@chr6:154707166..154707170
-
Hg19::chr6:154710410..154710428,-p@chr6:154710410..154710428
-
Hg19::chr6:154715743..154715749,-p@chr6:154715743..154715749
-
Hg19::chr6:154831779..154831801,-p1@CNKSR3
Hg19::chr6:154831810..154831825,-p3@CNKSR3
Hg19::chr6:154858334..154858342,-p@chr6:154858334..154858342
-
Hg19::chr6:154858693..154858698,+p@chr6:154858693..154858698
+
Hg19::chr6:154858754..154858762,+p@chr6:154858754..154858762
+
Hg19::chr6:1608025..1608034,+p@chr6:1608025..1608034
+
Hg19::chr6:161637770..161637773,-p@chr6:161637770..161637773
-
Hg19::chr6:169224860..169224875,+p@chr6:169224860..169224875
+
Hg19::chr6:21200990..21201016,+p3@CDKAL1
Hg19::chr6:21201020..21201041,+p4@CDKAL1
Hg19::chr6:39526005..39526014,-p@chr6:39526005..39526014
-
Hg19::chr7:128514881..128514892,-p@chr7:128514881..128514892
-
Hg19::chr7:138721040..138721056,+p@chr7:138721040..138721056
+
Hg19::chr7:147741638..147741652,+p@chr7:147741638..147741652
+
Hg19::chr7:147741662..147741672,+p@chr7:147741662..147741672
+
Hg19::chr7:147741674..147741689,+p@chr7:147741674..147741689
+
Hg19::chr7:147741691..147741703,+p@chr7:147741691..147741703
+
Hg19::chr7:157944243..157944249,-p@chr7:157944243..157944249
-
Hg19::chr7:1965161..1965171,-p@chr7:1965161..1965171
-
Hg19::chr7:1968200..1968208,-p@chr7:1968200..1968208
-
Hg19::chr7:1968236..1968246,-p@chr7:1968236..1968246
-
Hg19::chr7:1968249..1968274,-p@chr7:1968249..1968274
-
Hg19::chr7:1968292..1968302,-p@chr7:1968292..1968302
-
Hg19::chr7:1968315..1968322,-p@chr7:1968315..1968322
-
Hg19::chr7:1968325..1968349,-p@chr7:1968325..1968349
-
Hg19::chr7:26415872..26415875,-p4@ENST00000451368
Hg19::chr7:26415877..26415903,-p1@ENST00000451368
Hg19::chr7:26416577..26416604,-p5@ENST00000451264
Hg19::chr7:26439057..26439073,-p@chr7:26439057..26439073
-
Hg19::chr7:26565580..26565622,+p@chr7:26565580..26565622
+
Hg19::chr7:26589319..26589327,+p@chr7:26589319..26589327
+
Hg19::chr7:26590563..26590574,-p@chr7:26590563..26590574
-
Hg19::chr7:26590581..26590596,-p@chr7:26590581..26590596
-
Hg19::chr7:26590606..26590616,-p@chr7:26590606..26590616
-
Hg19::chr7:26657673..26657685,-p@chr7:26657673..26657685
-
Hg19::chr7:26657707..26657715,-p@chr7:26657707..26657715
-
Hg19::chr7:44574294..44574303,-p@chr7:44574294..44574303
-
Hg19::chr7:44574304..44574314,-p@chr7:44574304..44574314
-
Hg19::chr7:44574327..44574332,-p@chr7:44574327..44574332
-
Hg19::chr8:143295119..143295149,-p@chr8:143295119..143295149
-
Hg19::chr8:145731609..145731641,+p@chr8:145731609..145731641
+
Hg19::chr8:20487277..20487282,+p@chr8:20487277..20487282
+
Hg19::chr8:81084875..81084896,-p@chr8:81084875..81084896
-
Hg19::chr8:82275651..82275662,+p@chr8:82275651..82275662
+
Hg19::chr9:118982149..118982158,+p@chr9:118982149..118982158
+
Hg19::chr9:138661786..138661830,+p@chr9:138661786..138661830
+
Hg19::chr9:138999405..138999415,-p@chr9:138999405..138999415
-
Hg19::chr9:95426545..95426559,-p@chr9:95426545..95426559
-
Hg19::chrX:154251771..154251775,-p@chrX:154251771..154251775
-
Hg19::chrX:39923656..39923670,-p@chrX:39923656..39923670
-
Hg19::chrX:52840308..52840338,+p@chrX:52840308..52840338
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005329dopamine transmembrane transporter activity0.0361027159925986
GO:0004598peptidylamidoglycolate lyase activity0.0361027159925986
GO:0005330dopamine:sodium symporter activity0.0361027159925986
GO:0060134prepulse inhibition0.0361027159925986
GO:0042637catagen0.0361027159925986
GO:0042424catecholamine catabolic process0.0361027159925986
GO:0021984adenohypophysis development0.0361027159925986
GO:0042420dopamine catabolic process0.0361027159925986
GO:0004504peptidylglycine monooxygenase activity0.0361027159925986
GO:0048585negative regulation of response to stimulus0.0361027159925986
GO:0042069regulation of catecholamine metabolic process0.0361027159925986
GO:0005087Ran guanyl-nucleotide exchange factor activity0.0361027159925986
GO:0001964startle response0.0361027159925986
GO:0015872dopamine transport0.0361027159925986
GO:0042416dopamine biosynthetic process0.0361027159925986
GO:0032102negative regulation of response to external stimulus0.0361027159925986
GO:0042053regulation of dopamine metabolic process0.0361027159925986
GO:0008504monoamine transmembrane transporter activity0.0426118536849584
GO:0050709negative regulation of protein secretion0.0460106438605772
GO:0015844monoamine transport0.0460106438605772
GO:0048820hair follicle maturation0.0487883969281202
GO:0032101regulation of response to external stimulus0.0487883969281202



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
epithelial cell of lung6.95e-1219
Uber Anatomy
Ontology termp-valuen
respiratory tract epithelium6.95e-1219
lung epithelium6.95e-1219
lung1.80e-1022
respiratory tube1.80e-1022
respiration organ1.80e-1022
pair of lungs1.80e-1022
lung primordium1.80e-1022
lung bud1.80e-1022
respiratory system epithelium1.52e-0828
thoracic cavity element2.74e-0734
thoracic cavity2.74e-0734
thoracic segment organ4.03e-0735
epithelial bud8.21e-0737
Disease
Ontology termp-valuen
lung small cell carcinoma3.10e-504
bronchus cancer1.78e-297
bronchogenic carcinoma1.78e-297
lung carcinoma2.62e-239
lung cancer1.22e-1415
respiratory system cancer8.02e-1416


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.13.46676e-14
MA0004.14.9755
MA0006.10.163858
MA0007.10.0720426
MA0009.11.43127
MA0014.11.09451e-07
MA0017.10.0628997
MA0019.11.3246
MA0024.10.119605
MA0025.10.736344
MA0027.11.16868
MA0028.10.0647622
MA0029.10.480232
MA0030.10.126364
MA0031.14.58495
MA0038.10.183994
MA0040.10.289127
MA0041.12.57367
MA0042.12.15664
MA0043.10.434828
MA0046.10.412673
MA0048.10.0200015
MA0050.10.0789549
MA0051.10.280818
MA0052.11.45139
MA0055.10.252787
MA0056.10
MA0057.10.0012661
MA0058.16.04725
MA0059.11.41321
MA0060.10.0186448
MA0061.10.00164472
MA0063.10
MA0066.10.105969
MA0067.10.119562
MA0068.10.807559
MA0069.10.405175
MA0070.10.197412
MA0071.10.442098
MA0072.10.0745112
MA0073.10.000256202
MA0074.10.00675896
MA0076.11.37995
MA0077.11.253
MA0078.10.254211
MA0081.10.0972287
MA0083.10.237029
MA0084.11.18478
MA0087.10.919007
MA0088.10.038647
MA0089.10
MA0090.10.0601801
MA0091.11.02162
MA0092.10.23301
MA0093.17.8728
MA0095.10
MA0098.10
MA0100.10.210046
MA0101.10.00833278
MA0103.18.70407
MA0105.10.0207017
MA0106.10.0137474
MA0107.10.0123686
MA0108.20.495219
MA0109.10
MA0111.10.274886
MA0113.10.101666
MA0114.10.152259
MA0115.10.0867211
MA0116.10.0622779
MA0117.10.114427
MA0119.12.45351
MA0122.11.74522
MA0124.10.249606
MA0125.10.172595
MA0130.10
MA0131.10.00953387
MA0132.10
MA0133.10
MA0135.10.496866
MA0136.10.834269
MA0139.10.00316067
MA0140.10.0301395
MA0141.10.145238
MA0142.12.27345
MA0143.10.871494
MA0144.10.632773
MA0145.10.42843
MA0146.12.84854e-05
MA0147.11.41249
MA0148.118.031
MA0149.10.397422
MA0062.20.0709407
MA0035.20.429666
MA0039.22.39433e-09
MA0138.21.69851
MA0002.20.535587
MA0137.20.319792
MA0104.21.34015
MA0047.214.5224
MA0112.20.00119382
MA0065.20.0524186
MA0150.10.0920815
MA0151.10
MA0152.10.456769
MA0153.10.651251
MA0154.10.00318151
MA0155.11.07827
MA0156.11.19171
MA0157.14.88011
MA0158.10
MA0159.10.0274554
MA0160.10.498497
MA0161.10
MA0162.18.60952e-10
MA0163.13.6029e-09
MA0164.11.20333
MA0080.20.321647
MA0018.20.411653
MA0099.20.127951
MA0079.20
MA0102.20.245955
MA0258.10.0384837
MA0259.10.484001
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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