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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000467!1.23e-13!308;UBERON:0000480!1.23e-13!308;UBERON:0005423!2.61e-12!304;UBERON:0007023!2.08e-10!51;UBERON:0000923!2.50e-10!291;UBERON:0010316!2.50e-10!291;UBERON:0005291!2.50e-10!291;UBERON:0006598!2.50e-10!291;UBERON:0010317!2.50e-10!291;UBERON:0002532!2.50e-10!291;UBERON:0002050!2.55e-10!294;UBERON:0000477!1.12e-08!244
|ontology_enrichment_uberon=UBERON:0000467!1.23e-13!308;UBERON:0000480!1.23e-13!308;UBERON:0005423!2.61e-12!304;UBERON:0007023!2.08e-10!51;UBERON:0000923!2.50e-10!291;UBERON:0010316!2.50e-10!291;UBERON:0005291!2.50e-10!291;UBERON:0006598!2.50e-10!291;UBERON:0010317!2.50e-10!291;UBERON:0002532!2.50e-10!291;UBERON:0002050!2.55e-10!294;UBERON:0000477!1.12e-08!244
|tfbs_overrepresentation_for_novel_motifs=0.393008,0.121181,0.367606,0.434198,0.720982,0.448401,0.538088,0.515265,0.535519,0.0447303,0.494602,0.526159,0.173454,0.550255,0.756943,0,0.742571,0.703873,0.483643,0.0887261,0.332107,0.0622758,0.549359,0.258745,0.374936,0.577606,0.466037,0.469052,0.303071,0.376624,0.455168,0.843667,0.699026,0.425071,0.276324,0.185086,0.242032,0.522578,0.631914,0.195877,0.712303,0.460258,0.204736,0.27776,0.209497,0.423266,0.662995,0.484612,0.386968,0.305876,0.725127,0.604356,0.362495,0.985264,1.00271,0.557354,0.314394,0.513517,0.447041,0.555328,0.823643,0.613749,0.192045,0.713876,0.568415,0.754324,1.139,1.48833,0.818971,1.34113,0.349355,0.527912,0.0665967,1.03623,0.140213,0.409836,0.42492,0.651651,0.806481,0.336166,0.530481,0.759925,1.48701,0.167672,0.920903,0.025519,0.0299392,0.757533,0.667883,1.65055,1.20871,0.925879,0.856465,0.265734,0.218233,1.10739,0.982739,0.859272,0.663249,0.101559,1.26039,0.843387,0.967837,0.725721,0.724668,0.459825,0.784351,0.480639,0.340849,0.333829,1.00333,0.96962,0.337254,1.24884,1.21576,0.708441,0.143112,0.437894,0.743872,0.238599,1.04163,0.692953,0.579418,0.650748,1.26989,0.810177,0.546178,0.849691,1.13749,0.268537,0.950857,1.09252,1.10792,0.570914,1.23736,0.061199,0.401212,0.461647,1.18819,2.01886,1.6187,1.14372,0.591394,0.854131,0.718197,0.460705,0.666107,1.9792,0.403515,0.261837,0.120154,0.0553085,0.986833,0.207643,0.569994,1.06851,0.605358,0.287226,0.39061,0.400939,1.1977,0.920047,0.810622,0.383936,0.714896,0.562634,0.240994,0.524587,0.166768
}}
}}

Revision as of 19:06, 26 November 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:60043268..60043282,-p@chr11:60043268..60043282
-
Mm9::chr11:98216623..98216634,+p@chr11:98216623..98216634
+
Mm9::chr11:98218352..98218393,+p@chr11:98218352..98218393
+
Mm9::chr12:101444635..101444669,+p@chr12:101444635..101444669
+
Mm9::chr14:22652104..22652140,+p3@Vdac2
Mm9::chr3:101396429..101396470,-p@chr3:101396429..101396470
-
Mm9::chr4:154932366..154932388,+p@chr4:154932366..154932388
+
Mm9::chr6:17616260..17616279,+p@chr6:17616260..17616279
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:00038694-nitrophenylphosphatase activity0.0121607183681279
GO:0031944negative regulation of glucocorticoid metabolic process0.0121607183681279
GO:0031947negative regulation of glucocorticoid biosynthetic process0.0121607183681279
GO:0048521negative regulation of behavior0.0121607183681279
GO:0045989positive regulation of striated muscle contraction0.0121607183681279
GO:0007621negative regulation of female receptivity0.0121607183681279
GO:0005890sodium:potassium-exchanging ATPase complex0.0121607183681279
GO:0007603phototransduction, visible light0.0121607183681279
GO:0050795regulation of behavior0.0121607183681279
GO:0060181female receptivity0.0121607183681279
GO:0045924regulation of female receptivity0.0121607183681279
GO:0031946regulation of glucocorticoid biosynthetic process0.0121607183681279
GO:0006942regulation of striated muscle contraction0.0121607183681279
GO:0060180female mating behavior0.0121607183681279
GO:0030641cellular hydrogen ion homeostasis0.0159587566872052
GO:0031943regulation of glucocorticoid metabolic process0.0159587566872052
GO:0004865type 1 serine/threonine specific protein phosphatase inhibitor activity0.0170180109904335
GO:0007213acetylcholine receptor signaling, muscarinic pathway0.0170180109904335
GO:0006891intra-Golgi vesicle-mediated transport0.0170180109904335
GO:0043388positive regulation of DNA binding0.0170180109904335
GO:0045933positive regulation of muscle contraction0.0170180109904335
GO:0006704glucocorticoid biosynthetic process0.0170180109904335
GO:0045823positive regulation of heart contraction0.0170180109904335
GO:0008599protein phosphatase type 1 regulator activity0.0170180109904335
GO:0008308voltage-gated ion-selective channel activity0.0170180109904335
GO:0045822negative regulation of heart contraction0.0180444616373082
GO:0022892substrate-specific transporter activity0.0180444616373082
GO:0051099positive regulation of binding0.0180444616373082
GO:0019218regulation of steroid metabolic process0.0180444616373082
GO:0030004cellular monovalent inorganic cation homeostasis0.0180444616373082
GO:0015991ATP hydrolysis coupled proton transport0.0180444616373082
GO:0033057reproductive behavior in a multicellular organism0.0180444616373082
GO:0055067monovalent inorganic cation homeostasis0.0180444616373082
GO:0015988energy coupled proton transport, against electrochemical gradient0.0200129639191323
GO:0007617mating behavior0.021260861824116
GO:0008211glucocorticoid metabolic process0.021260861824116
GO:0005391sodium:potassium-exchanging ATPase activity0.0223767893786798
GO:0051101regulation of DNA binding0.0223767893786798
GO:0005795Golgi stack0.0239800433466738
GO:0002026regulation of the force of heart contraction0.0269502260834755
GO:0007618mating0.0269502260834755
GO:0019098reproductive behavior0.0283284086761825
GO:0004864protein phosphatase inhibitor activity0.0316137486258903
GO:0019212phosphatase inhibitor activity0.0350785630125739
GO:0019216regulation of lipid metabolic process0.0350785630125739
GO:0005741mitochondrial outer membrane0.0350785630125739
GO:0051098regulation of binding0.0361342198503228
GO:0030317sperm motility0.0366201476483536
GO:0031968organelle outer membrane0.0366201476483536
GO:0051705behavioral interaction between organisms0.0366201476483536
GO:0007602phototransduction0.0366201476483536
GO:0009584detection of visible light0.0377195160290655
GO:0050962detection of light stimulus during sensory perception0.0377195160290655
GO:0050908detection of light stimulus during visual perception0.0377195160290655
GO:0017111nucleoside-triphosphatase activity0.0393926317897043
GO:0009583detection of light stimulus0.0393926317897043
GO:0042383sarcolemma0.0396695758421618
GO:0016462pyrophosphatase activity0.0396695758421618
GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides0.0396695758421618
GO:0016817hydrolase activity, acting on acid anhydrides0.0396695758421618
GO:0051241negative regulation of multicellular organismal process0.0396695758421618
GO:0006941striated muscle contraction0.0396695758421618
GO:0042493response to drug0.0397496267172885
GO:0007200G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)0.0397496267172885
GO:0019888protein phosphatase regulator activity0.0417358677902161
GO:0006937regulation of muscle contraction0.0417496164970557
GO:0005834heterotrimeric G-protein complex0.0417496164970557
GO:0019208phosphatase regulator activity0.0435752009425995
GO:0042446hormone biosynthetic process0.0435752009425995
GO:0008016regulation of heart contraction0.0435752009425995
GO:0048193Golgi vesicle transport0.0453357959224003
GO:0008217regulation of blood pressure0.0470462002640027
GO:0048015phosphoinositide-mediated signaling0.048363880397671
GO:0003015heart process0.048363880397671
GO:0050909sensory perception of taste0.048363880397671
GO:0009582detection of abiotic stimulus0.048363880397671
GO:0060047heart contraction0.048363880397671
GO:0019867outer membrane0.0499003376276443



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
anatomical system1.23e-13308
anatomical group1.23e-13308
developing anatomical structure2.61e-12304
adult organism2.08e-1051
germ layer2.50e-10291
germ layer / neural crest2.50e-10291
embryonic tissue2.50e-10291
presumptive structure2.50e-10291
germ layer / neural crest derived structure2.50e-10291
epiblast (generic)2.50e-10291
embryonic structure2.55e-10294
anatomical cluster1.12e-08244


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}