MCL coexpression mm9:1092
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr11:85644728..85644768,+ | p@chr11:85644728..85644768 + |
| Mm9::chr11:85645796..85645812,- | p1@ENSMUST00000136117 p1@uc007krx.1 p1@uc007kry.1 |
| Mm9::chr11:85646263..85646278,+ | p2@Tbx2 |
| Mm9::chr11:85646303..85646329,+ | p1@Tbx2 |
| Mm9::chr11:85646341..85646352,+ | p3@Tbx2 |
| Mm9::chr11:85646427..85646451,+ | p4@Tbx2 |
| Mm9::chr11:85646469..85646488,+ | p5@Tbx2 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0007521 | muscle cell fate determination | 0.00427327014737304 |
| GO:0042693 | muscle cell fate commitment | 0.00427327014737304 |
| GO:0048738 | cardiac muscle development | 0.0128198104421191 |
| GO:0007569 | cell aging | 0.0138881279789624 |
| GO:0030879 | mammary gland development | 0.0170930805894921 |
| GO:0001709 | cell fate determination | 0.0170930805894921 |
| GO:0007568 | aging | 0.0170930805894921 |
| GO:0003007 | heart morphogenesis | 0.0181613981263354 |
| GO:0042692 | muscle cell differentiation | 0.0299128910316112 |
| GO:0048732 | gland development | 0.0316221990905605 |
| GO:0045165 | cell fate commitment | 0.038847910430664 |
| GO:0014706 | striated muscle development | 0.0434449131649592 |
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 0.0454034953158385 |
| GO:0016564 | transcription repressor activity | 0.0454034953158385 |
| GO:0007517 | muscle development | 0.0454034953158385 |
| GO:0007507 | heart development | 0.0454034953158385 |
| GO:0045892 | negative regulation of transcription, DNA-dependent | 0.0470059716211034 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| autonomic neuron | 3.45e-07 | 9 |
| Ontology term | p-value | n |
|---|---|---|
| lung | 3.63e-10 | 14 |
| respiratory tube | 3.63e-10 | 14 |
| respiration organ | 3.63e-10 | 14 |
| pair of lungs | 3.63e-10 | 14 |
| lung primordium | 3.63e-10 | 14 |
| lung bud | 3.63e-10 | 14 |
| multi-cellular organism | 4.57e-10 | 333 |
| epithelial fold | 1.29e-09 | 20 |
| anatomical space | 2.10e-08 | 57 |
| kidney | 4.08e-08 | 14 |
| kidney mesenchyme | 4.08e-08 | 14 |
| upper urinary tract | 4.08e-08 | 14 |
| kidney rudiment | 4.08e-08 | 14 |
| kidney field | 4.08e-08 | 14 |
| renal system | 6.12e-08 | 19 |
| epithelial bud | 9.85e-08 | 17 |
| trunk region element | 1.11e-07 | 79 |
| peripheral nervous system | 1.19e-07 | 11 |
| urinary system structure | 1.31e-07 | 18 |
| thoracic cavity element | 1.41e-07 | 17 |
| thoracic segment organ | 1.41e-07 | 17 |
| thoracic cavity | 1.41e-07 | 17 |
| thoracic segment of trunk | 1.41e-07 | 17 |
| respiratory primordium | 1.41e-07 | 17 |
| endoderm of foregut | 1.41e-07 | 17 |
| autonomic nervous system | 3.45e-07 | 9 |
| embryo | 3.62e-07 | 320 |
| subdivision of trunk | 5.62e-07 | 66 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 3.65284 |
| MA0004.1 | 0.481116 |
| MA0006.1 | 0.837454 |
| MA0007.1 | 1.17655 |
| MA0009.1 | 0.92425 |
| MA0014.1 | 0.222567 |
| MA0017.1 | 0.337808 |
| MA0019.1 | 0.740036 |
| MA0024.1 | 0.880057 |
| MA0025.1 | 1.15921 |
| MA0027.1 | 2.57545 |
| MA0028.1 | 0.321735 |
| MA0029.1 | 0.858105 |
| MA0030.1 | 0.864739 |
| MA0031.1 | 0.828781 |
| MA0038.1 | 0.62758 |
| MA0040.1 | 0.936879 |
| MA0041.1 | 0.404721 |
| MA0042.1 | 0.391504 |
| MA0043.1 | 1.02178 |
| MA0046.1 | 3.62248 |
| MA0048.1 | 0.128106 |
| MA0050.1 | 0.520357 |
| MA0051.1 | 0.636645 |
| MA0052.1 | 0.945011 |
| MA0055.1 | 0.157978 |
| MA0056.1 | 0 |
| MA0057.1 | 0.376102 |
| MA0058.1 | 0.384683 |
| MA0059.1 | 0.397033 |
| MA0060.1 | 1.22438 |
| MA0061.1 | 0.261749 |
| MA0063.1 | 0 |
| MA0066.1 | 0.616444 |
| MA0067.1 | 1.27078 |
| MA0068.1 | 0.385183 |
| MA0069.1 | 0.945354 |
| MA0070.1 | 0.93557 |
| MA0071.1 | 0.519509 |
| MA0072.1 | 0.927016 |
| MA0073.1 | 0.152496 |
| MA0074.1 | 0.580087 |
| MA0076.1 | 0.356883 |
| MA0077.1 | 0.905143 |
| MA0078.1 | 0.670113 |
| MA0081.1 | 0.420276 |
| MA0083.1 | 1.02098 |
| MA0084.1 | 1.59945 |
| MA0087.1 | 0.977537 |
| MA0088.1 | 0.285759 |
| MA0089.1 | 0 |
| MA0090.1 | 0.446539 |
| MA0091.1 | 0.494398 |
| MA0092.1 | 0.446857 |
| MA0093.1 | 0.329976 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.568369 |
| MA0101.1 | 0.406019 |
| MA0103.1 | 0.348572 |
| MA0105.1 | 0.162418 |
| MA0106.1 | 5.30337 |
| MA0107.1 | 0.342432 |
| MA0108.2 | 0.763162 |
| MA0109.1 | 0 |
| MA0111.1 | 0.460823 |
| MA0113.1 | 0.649407 |
| MA0114.1 | 0.259463 |
| MA0115.1 | 1.0246 |
| MA0116.1 | 3.18843 |
| MA0117.1 | 0.992087 |
| MA0119.1 | 0.40661 |
| MA0122.1 | 1.01209 |
| MA0124.1 | 1.21735 |
| MA0125.1 | 1.14291 |
| MA0130.1 | 0 |
| MA0131.1 | 0.735438 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.05845 |
| MA0136.1 | 0.600242 |
| MA0139.1 | 0.202522 |
| MA0140.1 | 0.568252 |
| MA0141.1 | 0.368264 |
| MA0142.1 | 0.814115 |
| MA0143.1 | 0.665982 |
| MA0144.1 | 0.262477 |
| MA0145.1 | 16.8711 |
| MA0146.1 | 3.11443 |
| MA0147.1 | 0.753844 |
| MA0148.1 | 0.49752 |
| MA0149.1 | 0.411562 |
| MA0062.2 | 0.167299 |
| MA0035.2 | 0.573016 |
| MA0039.2 | 1.72008 |
| MA0138.2 | 0.727395 |
| MA0002.2 | 0.205289 |
| MA0137.2 | 0.365364 |
| MA0104.2 | 1.17226 |
| MA0047.2 | 0.626803 |
| MA0112.2 | 2.13872 |
| MA0065.2 | 2.14244 |
| MA0150.1 | 0.465855 |
| MA0151.1 | 0 |
| MA0152.1 | 1.5176 |
| MA0153.1 | 1.07519 |
| MA0154.1 | 1.29007 |
| MA0155.1 | 2.94388 |
| MA0156.1 | 0.356017 |
| MA0157.1 | 0.781683 |
| MA0158.1 | 0 |
| MA0159.1 | 0.776527 |
| MA0160.1 | 0.50056 |
| MA0161.1 | 0 |
| MA0162.1 | 4.62777 |
| MA0163.1 | 1.63182 |
| MA0164.1 | 0.600609 |
| MA0080.2 | 0.343316 |
| MA0018.2 | 0.610433 |
| MA0099.2 | 0.721008 |
| MA0079.2 | 3.46801 |
| MA0102.2 | 1.65195 |
| MA0258.1 | 1.27611 |
| MA0259.1 | 0.26402 |
| MA0442.1 | 0 |
