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MCL coexpression mm9:1743

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Phase1 CAGE Peaks

 Short description
Mm9::chr1:166726889..166726900,+p@chr1:166726889..166726900
+
Mm9::chr3:58934984..58935003,-p4@P2ry14
Mm9::chr3:58935005..58935016,-p11@P2ry14
Mm9::chr3:58935044..58935063,-p3@P2ry14
Mm9::chr3:58935149..58935161,-p8@P2ry14


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0045028purinergic nucleotide receptor activity, G-protein coupled0.0256150376404581
GO:0001608nucleotide receptor activity, G-protein coupled0.0256150376404581
GO:0016502nucleotide receptor activity0.0256150376404581
GO:0001614purinergic nucleotide receptor activity0.0256150376404581



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
lung5.50e-1314
respiratory tube5.50e-1314
respiration organ5.50e-1314
pair of lungs5.50e-1314
lung primordium5.50e-1314
lung bud5.50e-1314
subdivision of digestive tract4.32e-10114
epithelial bud7.82e-1017
thoracic cavity element7.82e-1017
thoracic segment organ7.82e-1017
thoracic cavity7.82e-1017
thoracic segment of trunk7.82e-1017
respiratory primordium7.82e-1017
endoderm of foregut7.82e-1017
gastrointestinal system8.59e-1047
digestive system1.20e-09116
digestive tract1.20e-09116
primitive gut1.20e-09116
endoderm-derived structure3.18e-09118
endoderm3.18e-09118
presumptive endoderm3.18e-09118
subdivision of trunk6.33e-0966
stomach1.43e-0816
food storage organ1.43e-0816
epithelial fold1.14e-0720
trunk region element1.33e-0779


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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