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Coexpression cluster:C97

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Full id: C97_small_smallcell_gastrointestinal_argyrophil_putamen_duodenum_brain



Phase1 CAGE Peaks

Hg19::chr10:113748431..113748441,-p@chr10:113748431..113748441
-
Hg19::chr10:120355149..120355165,-p1@PRLHR
Hg19::chr11:129305906..129305908,+p7@BARX2
Hg19::chr11:1643561..1643566,+p@chr11:1643561..1643566
+
Hg19::chr11:18034532..18034548,-p4@SERGEF
Hg19::chr11:26618692..26618727,-p@chr11:26618692..26618727
-
Hg19::chr11:26618988..26619017,-p@chr11:26618988..26619017
-
Hg19::chr11:42912594..42912599,-p@chr11:42912594..42912599
-
Hg19::chr11:42912793..42912802,-p@chr11:42912793..42912802
-
Hg19::chr11:4665150..4665166,+p2@OR51E1
Hg19::chr11:4665183..4665193,+p3@OR51E1
Hg19::chr11:4665195..4665219,+p1@OR51E1
Hg19::chr11:4726012..4726018,+p1@MMP26
Hg19::chr11:4726112..4726125,+p2@MMP26
Hg19::chr11:4807754..4807756,+p1@OR51N1P
Hg19::chr11:5445690..5445716,+p@chr11:5445690..5445716
+
Hg19::chr11:67402354..67402359,-p@chr11:67402354..67402359
-
Hg19::chr11:67402368..67402378,-p@chr11:67402368..67402378
-
Hg19::chr11:78177190..78177210,-p@chr11:78177190..78177210
-
Hg19::chr12:127545156..127545162,+p@chr12:127545156..127545162
+
Hg19::chr12:132556644..132556656,+p@chr12:132556644..132556656
+
Hg19::chr12:51116443..51116452,+p@chr12:51116443..51116452
+
Hg19::chr12:53686428..53686432,+p@chr12:53686428..53686432
+
Hg19::chr12:53686472..53686482,+p@chr12:53686472..53686482
+
Hg19::chr12:58158560..58158567,-p@chr12:58158560..58158567
-
Hg19::chr12:76206813..76206837,-p@chr12:76206813..76206837
-
Hg19::chr13:25269076..25269105,-p@chr13:25269076..25269105
-
Hg19::chr13:25269257..25269262,+p@chr13:25269257..25269262
+
Hg19::chr14:36966895..36966899,-p@chr14:36966895..36966899
-
Hg19::chr14:57127818..57127825,+p@chr14:57127818..57127825
+
Hg19::chr14:57127856..57127863,+p@chr14:57127856..57127863
+
Hg19::chr15:62007373..62007374,-p2@ENST00000559590
Hg19::chr15:62007379..62007390,-p1@ENST00000559590
Hg19::chr16:11846874..11846885,-p14@ZC3H7A
Hg19::chr16:19396252..19396261,+p@chr16:19396252..19396261
+
Hg19::chr16:30015874..30015893,+p@chr16:30015874..30015893
+
Hg19::chr16:7354032..7354043,+p@chr16:7354032..7354043
+
Hg19::chr16:7354527..7354551,-p@chr16:7354527..7354551
-
Hg19::chr16:7354636..7354645,-p@chr16:7354636..7354645
-
Hg19::chr16:7354657..7354690,-p@chr16:7354657..7354690
-
Hg19::chr16:7428243..7428259,+p@chr16:7428243..7428259
+
Hg19::chr16:83649377..83649388,+p@chr16:83649377..83649388
+
Hg19::chr16:83649482..83649491,+p@chr16:83649482..83649491
+
Hg19::chr16:8524660..8524680,-p@chr16:8524660..8524680
-
Hg19::chr17:27308382..27308398,+p@chr17:27308382..27308398
+
Hg19::chr17:27333028..27333089,-p1@SEZ6
Hg19::chr17:27333187..27333207,-p13@SEZ6
Hg19::chr17:27333311..27333318,-p21@SEZ6
Hg19::chr17:39140393..39140399,-p3@KRT40
Hg19::chr17:39140411..39140419,-p5@KRT40
Hg19::chr17:39140424..39140431,-p4@KRT40
Hg19::chr17:39140549..39140579,-p1@KRT40
Hg19::chr17:43749913..43749923,+p@chr17:43749913..43749923
+
Hg19::chr17:78560489..78560497,+p@chr17:78560489..78560497
+
Hg19::chr18:31185530..31185578,+p@chr18:31185530..31185578
+
Hg19::chr18:33311016..33311032,-p@chr18:33311016..33311032
-
Hg19::chr18:35250432..35250444,+p@chr18:35250432..35250444
+
Hg19::chr18:73967160..73967162,-p@chr18:73967160..73967162
-
Hg19::chr18:73967189..73967200,-p@chr18:73967189..73967200
-
Hg19::chr18:73967203..73967220,-p@chr18:73967203..73967220
-
Hg19::chr18:74671119..74671124,+p@chr18:74671119..74671124
+
Hg19::chr18:8331753..8331793,+p@chr18:8331753..8331793
+
Hg19::chr19:46520090..46520102,-p@chr19:46520090..46520102
-
Hg19::chr19:46531064..46531073,+p@chr19:46531064..46531073
+
Hg19::chr19:46531131..46531136,+p@chr19:46531131..46531136
+
Hg19::chr19:46763326..46763349,+p@chr19:46763326..46763349
+
Hg19::chr19:46763651..46763662,+p@chr19:46763651..46763662
+
Hg19::chr19:46763803..46763808,-p@chr19:46763803..46763808
-
Hg19::chr19:51586029..51586039,-p2@KLK14
Hg19::chr19:56681707..56681748,-p@chr19:56681707..56681748
-
Hg19::chr19:9811101..9811112,-p3@ZNF812
Hg19::chr19:9811125..9811144,-p2@ZNF812
Hg19::chr1:11908185..11908202,-p6@NPPA
Hg19::chr1:11908227..11908236,-p8@NPPA
Hg19::chr1:15904346..15904358,-p@chr1:15904346..15904358
-
Hg19::chr1:194327155..194327162,-p@chr1:194327155..194327162
-
Hg19::chr1:223276523..223276530,-p@chr1:223276523..223276530
-
Hg19::chr1:223919301..223919303,+p@chr1:223919301..223919303
+
Hg19::chr1:225650299..225650317,-p@chr1:225650299..225650317
-
Hg19::chr1:226071797..226071822,-p@chr1:226071797..226071822
-
Hg19::chr1:28384655..28384680,-p7@EYA3
Hg19::chr1:6534668..6534704,-p@chr1:6534668..6534704
-
Hg19::chr1:67021937..67021942,+p@chr1:67021937..67021942
+
Hg19::chr1:79654075..79654086,-p@chr1:79654075..79654086
-
Hg19::chr21:29774393..29774422,-p@chr21:29774393..29774422
-
Hg19::chr21:29774431..29774441,-p@chr21:29774431..29774441
-
Hg19::chr21:39465959..39465961,+p@chr21:39465959..39465961
+
Hg19::chr21:43917055..43917058,-p@chr21:43917055..43917058
-
Hg19::chr22:38539185..38539224,-p9@PLA2G6
Hg19::chr22:38539262..38539297,-p11@PLA2G6
Hg19::chr2:120488121..120488144,-p@chr2:120488121..120488144
-
Hg19::chr2:148259693..148259714,-p@chr2:148259693..148259714
-
Hg19::chr2:170573896..170573900,-p@chr2:170573896..170573900
-
Hg19::chr2:176962389..176962394,-p@chr2:176962389..176962394
-
Hg19::chr2:21444025..21444055,+p1@ENST00000435237
Hg19::chr2:234862280..234862298,+p9@TRPM8
Hg19::chr2:234862313..234862320,+p15@TRPM8
Hg19::chr2:234862392..234862408,+p5@TRPM8
Hg19::chr2:234862409..234862414,+p14@TRPM8
Hg19::chr2:234862417..234862434,+p6@TRPM8
Hg19::chr2:234862436..234862439,+p16@TRPM8
Hg19::chr2:235841327..235841336,+p@chr2:235841327..235841336
+
Hg19::chr2:238385078..238385087,-p@chr2:238385078..238385087
-
Hg19::chr2:241625343..241625356,+p4@ENST00000407635
Hg19::chr2:241625364..241625374,+p5@ENST00000407635
Hg19::chr2:241625384..241625391,+p10@ENST00000407635
Hg19::chr2:241625475..241625482,+p8@ENST00000407635
Hg19::chr2:241625540..241625541,+p14@ENST00000407635
Hg19::chr2:241625548..241625569,+p1@ENST00000407635
Hg19::chr2:241625621..241625629,+p2@ENST00000407635
Hg19::chr2:241625689..241625696,+p7@ENST00000407635
Hg19::chr2:241625703..241625706,+p12@ENST00000407635
Hg19::chr2:28785672..28785682,+p@chr2:28785672..28785682
+
Hg19::chr2:28785693..28785704,+p@chr2:28785693..28785704
+
Hg19::chr2:28785707..28785729,+p@chr2:28785707..28785729
+
Hg19::chr2:3131535..3131547,-p@chr2:3131535..3131547
-
Hg19::chr3:102635374..102635381,-p@chr3:102635374..102635381
-
Hg19::chr3:102635409..102635414,-p@chr3:102635409..102635414
-
Hg19::chr3:102635473..102635480,-p@chr3:102635473..102635480
-
Hg19::chr3:142338164..142338210,+p@chr3:142338164..142338210
+
Hg19::chr3:145094664..145094665,+p@chr3:145094664..145094665
+
Hg19::chr4:10734349..10734351,-p@chr4:10734349..10734351
-
Hg19::chr4:185018490..185018512,-p@chr4:185018490..185018512
-
Hg19::chr4:185426203..185426209,-p@chr4:185426203..185426209
-
Hg19::chr4:23882555..23882575,-p4@HQ695733
Hg19::chr4:3310694..3310716,-p@chr4:3310694..3310716
-
Hg19::chr4:3344392..3344399,+p@chr4:3344392..3344399
+
Hg19::chr4:3344412..3344423,+p@chr4:3344412..3344423
+
Hg19::chr4:3344434..3344441,+p@chr4:3344434..3344441
+
Hg19::chr4:3344577..3344588,+p@chr4:3344577..3344588
+
Hg19::chr5:102141951..102141981,+p@chr5:102141951..102141981
+
Hg19::chr5:102143544..102143550,+p42@PAM
Hg19::chr5:102143894..102143910,+p6@PAM
Hg19::chr5:1445539..1445558,-p1@SLC6A3
Hg19::chr5:30198094..30198099,+p@chr5:30198094..30198099
+
Hg19::chr5:79097476..79097484,+p@chr5:79097476..79097484
+
Hg19::chr6:104852320..104852330,-p@chr6:104852320..104852330
-
Hg19::chr6:154707166..154707170,-p@chr6:154707166..154707170
-
Hg19::chr6:154710410..154710428,-p@chr6:154710410..154710428
-
Hg19::chr6:154715743..154715749,-p@chr6:154715743..154715749
-
Hg19::chr6:154831779..154831801,-p1@CNKSR3
Hg19::chr6:154831810..154831825,-p3@CNKSR3
Hg19::chr6:154858334..154858342,-p@chr6:154858334..154858342
-
Hg19::chr6:154858693..154858698,+p@chr6:154858693..154858698
+
Hg19::chr6:154858754..154858762,+p@chr6:154858754..154858762
+
Hg19::chr6:1608025..1608034,+p@chr6:1608025..1608034
+
Hg19::chr6:161637770..161637773,-p@chr6:161637770..161637773
-
Hg19::chr6:169224860..169224875,+p@chr6:169224860..169224875
+
Hg19::chr6:21200990..21201016,+p3@CDKAL1
Hg19::chr6:21201020..21201041,+p4@CDKAL1
Hg19::chr6:39526005..39526014,-p@chr6:39526005..39526014
-
Hg19::chr7:128514881..128514892,-p@chr7:128514881..128514892
-
Hg19::chr7:138721040..138721056,+p@chr7:138721040..138721056
+
Hg19::chr7:147741638..147741652,+p@chr7:147741638..147741652
+
Hg19::chr7:147741662..147741672,+p@chr7:147741662..147741672
+
Hg19::chr7:147741674..147741689,+p@chr7:147741674..147741689
+
Hg19::chr7:147741691..147741703,+p@chr7:147741691..147741703
+
Hg19::chr7:157944243..157944249,-p@chr7:157944243..157944249
-
Hg19::chr7:1965161..1965171,-p@chr7:1965161..1965171
-
Hg19::chr7:1968200..1968208,-p@chr7:1968200..1968208
-
Hg19::chr7:1968236..1968246,-p@chr7:1968236..1968246
-
Hg19::chr7:1968249..1968274,-p@chr7:1968249..1968274
-
Hg19::chr7:1968292..1968302,-p@chr7:1968292..1968302
-
Hg19::chr7:1968315..1968322,-p@chr7:1968315..1968322
-
Hg19::chr7:1968325..1968349,-p@chr7:1968325..1968349
-
Hg19::chr7:26415872..26415875,-p4@ENST00000451368
Hg19::chr7:26415877..26415903,-p1@ENST00000451368
Hg19::chr7:26416577..26416604,-p5@ENST00000451264
Hg19::chr7:26439057..26439073,-p@chr7:26439057..26439073
-
Hg19::chr7:26565580..26565622,+p@chr7:26565580..26565622
+
Hg19::chr7:26589319..26589327,+p@chr7:26589319..26589327
+
Hg19::chr7:26590563..26590574,-p@chr7:26590563..26590574
-
Hg19::chr7:26590581..26590596,-p@chr7:26590581..26590596
-
Hg19::chr7:26590606..26590616,-p@chr7:26590606..26590616
-
Hg19::chr7:26657673..26657685,-p@chr7:26657673..26657685
-
Hg19::chr7:26657707..26657715,-p@chr7:26657707..26657715
-
Hg19::chr7:44574294..44574303,-p@chr7:44574294..44574303
-
Hg19::chr7:44574304..44574314,-p@chr7:44574304..44574314
-
Hg19::chr7:44574327..44574332,-p@chr7:44574327..44574332
-
Hg19::chr8:143295119..143295149,-p@chr8:143295119..143295149
-
Hg19::chr8:145731609..145731641,+p@chr8:145731609..145731641
+
Hg19::chr8:20487277..20487282,+p@chr8:20487277..20487282
+
Hg19::chr8:81084875..81084896,-p@chr8:81084875..81084896
-
Hg19::chr8:82275651..82275662,+p@chr8:82275651..82275662
+
Hg19::chr9:118982149..118982158,+p@chr9:118982149..118982158
+
Hg19::chr9:138661786..138661830,+p@chr9:138661786..138661830
+
Hg19::chr9:138999405..138999415,-p@chr9:138999405..138999415
-
Hg19::chr9:95426545..95426559,-p@chr9:95426545..95426559
-
Hg19::chrX:154251771..154251775,-p@chrX:154251771..154251775
-
Hg19::chrX:39923656..39923670,-p@chrX:39923656..39923670
-
Hg19::chrX:52840308..52840338,+p@chrX:52840308..52840338
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005329dopamine transmembrane transporter activity0.0361027159925986
GO:0004598peptidylamidoglycolate lyase activity0.0361027159925986
GO:0005330dopamine:sodium symporter activity0.0361027159925986
GO:0060134prepulse inhibition0.0361027159925986
GO:0042637catagen0.0361027159925986
GO:0042424catecholamine catabolic process0.0361027159925986
GO:0021984adenohypophysis development0.0361027159925986
GO:0042420dopamine catabolic process0.0361027159925986
GO:0004504peptidylglycine monooxygenase activity0.0361027159925986
GO:0048585negative regulation of response to stimulus0.0361027159925986
GO:0042069regulation of catecholamine metabolic process0.0361027159925986
GO:0005087Ran guanyl-nucleotide exchange factor activity0.0361027159925986
GO:0001964startle response0.0361027159925986
GO:0015872dopamine transport0.0361027159925986
GO:0042416dopamine biosynthetic process0.0361027159925986
GO:0032102negative regulation of response to external stimulus0.0361027159925986
GO:0042053regulation of dopamine metabolic process0.0361027159925986
GO:0008504monoamine transmembrane transporter activity0.0426118536849584
GO:0050709negative regulation of protein secretion0.0460106438605772
GO:0015844monoamine transport0.0460106438605772
GO:0048820hair follicle maturation0.0487883969281202
GO:0032101regulation of response to external stimulus0.0487883969281202



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
epithelial cell of lung6.95e-1219
Uber Anatomy
Ontology termp-valuen
respiratory tract epithelium6.95e-1219
lung epithelium6.95e-1219
lung1.80e-1022
respiratory tube1.80e-1022
respiration organ1.80e-1022
pair of lungs1.80e-1022
lung primordium1.80e-1022
lung bud1.80e-1022
respiratory system epithelium1.52e-0828
thoracic cavity element2.74e-0734
thoracic cavity2.74e-0734
thoracic segment organ4.03e-0735
epithelial bud8.21e-0737
Disease
Ontology termp-valuen
lung small cell carcinoma3.10e-504
bronchus cancer1.78e-297
bronchogenic carcinoma1.78e-297
lung carcinoma2.62e-239
lung cancer1.22e-1415
respiratory system cancer8.02e-1416


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data