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Coexpression cluster:C605

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Full id: C605_hepatic_normal_osteoclastoma_tenocyte_neurofibroma_Ewing_mesothelioma



Phase1 CAGE Peaks

Hg19::chr3:120113800..120113812,-p14@FSTL1
Hg19::chr3:120114219..120114235,-p2@FSTL1
Hg19::chr3:120114674..120114689,-p3@MIR198
Hg19::chr3:120114721..120114737,-p1@MIR198
Hg19::chr3:120114861..120114881,-p2@MIR198
Hg19::chr3:120115113..120115129,-p5@FSTL1
Hg19::chr3:120115138..120115175,-p9@FSTL1
Hg19::chr3:120115192..120115245,-p3@FSTL1
Hg19::chr3:120115609..120115624,-p@chr3:120115609..120115624
-
Hg19::chr3:120115780..120115817,+p@chr3:120115780..120115817
+
Hg19::chr3:120121735..120121755,-p@chr3:120121735..120121755
-
Hg19::chr3:120122172..120122207,-p11@FSTL1
Hg19::chr3:120128408..120128463,-p@chr3:120128408..120128463
-
Hg19::chr3:120128496..120128516,-p@chr3:120128496..120128516
-
Hg19::chr3:120169828..120169850,-p1@FSTL1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008201heparin binding0.0102805251383492
GO:0005539glycosaminoglycan binding0.0102805251383492
GO:0030247polysaccharide binding0.0102805251383492
GO:0001871pattern binding0.0102805251383492
GO:0030246carbohydrate binding0.0284940539267632
GO:0005615extracellular space0.0284940539267632
GO:0044421extracellular region part0.0420934887554456



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
skeletal muscle tissue2.49e-1262
striated muscle tissue2.49e-1262
myotome2.49e-1262
muscle tissue4.25e-1264
musculature4.25e-1264
musculature of body4.25e-1264
dense mesenchyme tissue1.82e-1173
somite2.37e-1171
presomitic mesoderm2.37e-1171
presumptive segmental plate2.37e-1171
dermomyotome2.37e-1171
trunk paraxial mesoderm2.37e-1171
multilaminar epithelium3.98e-1183
paraxial mesoderm6.37e-1172
presumptive paraxial mesoderm6.37e-1172
epithelial vesicle1.74e-0978
splanchnic layer of lateral plate mesoderm1.82e-0983
vasculature1.75e-0878
vascular system1.75e-0878
mesenchyme1.76e-08160
entire embryonic mesenchyme1.76e-08160
trunk mesenchyme4.30e-08122
artery4.69e-0842
arterial blood vessel4.69e-0842
arterial system4.69e-0842
organ component layer2.20e-0766
circulatory system6.68e-07112
epithelial tube open at both ends9.41e-0759
blood vessel9.41e-0759
blood vasculature9.41e-0759
vascular cord9.41e-0759


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.000385441
MA0004.10.256222
MA0006.10.137644
MA0007.10.67744
MA0009.10.669377
MA0014.10.0332175
MA0017.10.16476
MA0019.10.38027
MA0024.10.570967
MA0025.10.796882
MA0027.12.25966
MA0028.10.148561
MA0029.10.588958
MA0030.10.578277
MA0031.10.518602
MA0038.10.34128
MA0040.10.594421
MA0041.11.36862
MA0042.11.27338
MA0043.10.669676
MA0046.10.659066
MA0048.10.0212749
MA0050.10.246257
MA0051.10.896276
MA0052.10.598036
MA0055.10.120131
MA0056.10
MA0057.10.420982
MA0058.10.182945
MA0059.10.182001
MA0060.10.237888
MA0061.10.767139
MA0063.10
MA0066.10.341645
MA0067.10.975379
MA0068.10.341559
MA0069.11.57719
MA0070.10.644843
MA0071.10.308534
MA0072.10.640598
MA0073.18.00756e-06
MA0074.11.60579
MA0076.10.194691
MA0077.10.633326
MA0078.10.424186
MA0081.10.536866
MA0083.11.62113
MA0084.11.15904
MA0087.10.63829
MA0088.10.426561
MA0089.10
MA0090.10.205547
MA0091.10.258318
MA0092.10.647316
MA0093.10.139688
MA0095.10
MA0098.10
MA0100.10.353174
MA0101.10.141917
MA0103.10.131472
MA0105.10.192891
MA0106.10.37688
MA0107.10.315431
MA0108.20.515791
MA0109.10
MA0111.10.215855
MA0113.10.39123
MA0114.10.0920489
MA0115.10.900969
MA0116.10.660297
MA0117.11.6806
MA0119.10.170362
MA0122.10.729811
MA0124.10.860724
MA0125.10.779672
MA0130.10
MA0131.10.440395
MA0132.10
MA0133.10
MA0135.10.698212
MA0136.10.347318
MA0139.10.0481205
MA0140.10.30631
MA0141.10.180729
MA0142.11.2271
MA0143.11.79503
MA0144.10.0838502
MA0145.10.0493052
MA0146.10.000217915
MA0147.10.0991954
MA0148.12.13038
MA0149.10.298252
MA0062.20.0512998
MA0035.20.305721
MA0039.20.00240387
MA0138.20.425279
MA0002.20.220677
MA0137.20.153033
MA0104.20.0667907
MA0047.20.959769
MA0112.20.00868143
MA0065.20.0514203
MA0150.10.201098
MA0151.10
MA0152.10.311809
MA0153.10.763487
MA0154.10.187751
MA0155.10.0403226
MA0156.10.154615
MA0157.10.46471
MA0158.10
MA0159.10.0995776
MA0160.10.288813
MA0161.10
MA0162.10.0065085
MA0163.10.393441
MA0164.11.03839
MA0080.20.139746
MA0018.20.378086
MA0099.20.312108
MA0079.23.69917e-05
MA0102.21.1957
MA0258.10.0785319
MA0259.10.104286
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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